Objective:To evaluate the curative effect of surgical treatment of vocal cord polyp under self-retaining fibrolaryngoscope and fibrolaryngoscope.Methods: A total of 118 patients with vocal cord polyp who received surg...Objective:To evaluate the curative effect of surgical treatment of vocal cord polyp under self-retaining fibrolaryngoscope and fibrolaryngoscope.Methods: A total of 118 patients with vocal cord polyp who received surgical treatment in our hospital between August 2013 and August 2015 were included in the study, the treatment process was retrospectively analyzed, and according to different operation methods, patients were divided into observation group (n=61) who received surgical treatment under self-retaining fibrolaryngoscope and control group (n=57) who received surgical treatment under fibrolaryngoscope. Differences in voice electroglottography parameters, oxidative stress system indexes, trauma-related indexes and so on were compared between two groups of patients 2 weeks after operation.Results:Jitter, Shimmer and NNE levels of observation group were significantly lower than those of control group while HNR and SNR levels were significantly higher than those of control group;SOD T, SOD Cu-Zn and T-AOC content in serum of observation group were significantly higher than those of control group while H2O2 and AOPP content were significantly lower than those of control group;NPY,β-EP, PGI2, HMGB-1 and HSP72 content in serum of observation group were significantly lower than those of control group.Conclusions:Surgery under self-retaining fibrolaryngoscope can better realize the accurate resection of vocal cord polyp, protect the normal vocal cord function and also reduce the body trauma, and it is a more ideal way of surgery.展开更多
The geometric and biomechanical properties of the larynx strongly influence voice quality and efficiency. A physical understanding of phonation natures in pathological conditions is important for predictions of how vo...The geometric and biomechanical properties of the larynx strongly influence voice quality and efficiency. A physical understanding of phonation natures in pathological conditions is important for predictions of how voice disorders can be treated using therapy and rehabilitation. Here, we present a continuum-based numerical model of phonation that considers complex fluid-structure interactions occurring in the airway. This model considers a three-dimensional geometry of vocal folds, muscle contractions, and viscoelastic properties to provide a realistic framework of phonation. The vocal fold motion is coupled to an unsteady compressible respiratory flow, allowing numerical simulations of normal and diseased phonations to derive clear relationships between actual laryngeal structures and model parameters such as muscle activity. As a pilot analysis of diseased phonation, we model vocal nodules, the mass lesions that can appear bilaterally on both sides of the vocal folds. Comparison of simulations with and without the nodules demonstrates how the lesions affect vocal fold motion, consequently restricting voice quality. Furthermore, we found that the minimum lung pressure required for voice production increases as nodules move closer to the center of the vocal fold. Thus, simulations using the developed model may provide essential insight into complex phonation phenomena and further elucidate the etiologic mechanisms of voice disorders.展开更多
文摘Objective:To evaluate the curative effect of surgical treatment of vocal cord polyp under self-retaining fibrolaryngoscope and fibrolaryngoscope.Methods: A total of 118 patients with vocal cord polyp who received surgical treatment in our hospital between August 2013 and August 2015 were included in the study, the treatment process was retrospectively analyzed, and according to different operation methods, patients were divided into observation group (n=61) who received surgical treatment under self-retaining fibrolaryngoscope and control group (n=57) who received surgical treatment under fibrolaryngoscope. Differences in voice electroglottography parameters, oxidative stress system indexes, trauma-related indexes and so on were compared between two groups of patients 2 weeks after operation.Results:Jitter, Shimmer and NNE levels of observation group were significantly lower than those of control group while HNR and SNR levels were significantly higher than those of control group;SOD T, SOD Cu-Zn and T-AOC content in serum of observation group were significantly higher than those of control group while H2O2 and AOPP content were significantly lower than those of control group;NPY,β-EP, PGI2, HMGB-1 and HSP72 content in serum of observation group were significantly lower than those of control group.Conclusions:Surgery under self-retaining fibrolaryngoscope can better realize the accurate resection of vocal cord polyp, protect the normal vocal cord function and also reduce the body trauma, and it is a more ideal way of surgery.
文摘The geometric and biomechanical properties of the larynx strongly influence voice quality and efficiency. A physical understanding of phonation natures in pathological conditions is important for predictions of how voice disorders can be treated using therapy and rehabilitation. Here, we present a continuum-based numerical model of phonation that considers complex fluid-structure interactions occurring in the airway. This model considers a three-dimensional geometry of vocal folds, muscle contractions, and viscoelastic properties to provide a realistic framework of phonation. The vocal fold motion is coupled to an unsteady compressible respiratory flow, allowing numerical simulations of normal and diseased phonations to derive clear relationships between actual laryngeal structures and model parameters such as muscle activity. As a pilot analysis of diseased phonation, we model vocal nodules, the mass lesions that can appear bilaterally on both sides of the vocal folds. Comparison of simulations with and without the nodules demonstrates how the lesions affect vocal fold motion, consequently restricting voice quality. Furthermore, we found that the minimum lung pressure required for voice production increases as nodules move closer to the center of the vocal fold. Thus, simulations using the developed model may provide essential insight into complex phonation phenomena and further elucidate the etiologic mechanisms of voice disorders.
