期刊文献+
共找到280,797篇文章
< 1 2 250 >
每页显示 20 50 100
Wigner-Ville distribution and cross Wigner-Ville distribution of noisy signals 被引量:4
1
作者 Chen Guanghua Ma Shiwei Liu Ming Zhu Jingming Zeng Weimin 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2008年第5期1053-1057,共5页
The Wigner-Ville distribution (WVD) and the cross Wigner-Ville distribution (XWVD) have been shown to be efficient in the estimation of instantaneous frequency (IF). But the statistical result of the IF estimati... The Wigner-Ville distribution (WVD) and the cross Wigner-Ville distribution (XWVD) have been shown to be efficient in the estimation of instantaneous frequency (IF). But the statistical result of the IF estimation from XWVD peak is much better than using WVD peak. The reason is given from a statistical point of view. Theoretical studies show that XWVD of the analyzed signal can be estimated from XWVD of the noise-contaminated signal. The estimation is unbiased, and the variance is equal to that of noise. In this case, WVD cannot be estimated from W-VD of the noise-contaminated signal. Therefore, higher SNR is required when WVD is used to analyze signals. 展开更多
关键词 wigner-ville distribution cross wigner-ville distribution instantaneous frequency EXPECTATION variance.
下载PDF
Statistical Performance of the Wigner-Ville Distribution and the Cross Wigner-Ville Distribution 被引量:2
2
作者 陈光化 曹家麟 《Journal of Shanghai University(English Edition)》 CAS 2003年第4期379-383,共5页
This paper analyzes statistical performances of the Wigner-Ville distribution (WVD) and the cross Wigner-Ville distribution (XWVD). Theoretical studies show that XWVD of the analyzed signal can be estimated from XWVD ... This paper analyzes statistical performances of the Wigner-Ville distribution (WVD) and the cross Wigner-Ville distribution (XWVD). Theoretical studies show that XWVD of the analyzed signal can be estimated from XWVD of the noise-contaminated signal . The estimation is unbiased, and the variance is equal to that of noise. In this case, WVD cannot be estimated from WVD of the noise-contaminated signal . Therefore higher SNR is required when using WVD. 展开更多
关键词 wigner-ville distribution cross wigner-ville distribution instantaneous frequency variance.
下载PDF
Improvement on polynomial Wigner-Ville distribution for detecting higher-order polynomial phase signal 被引量:4
3
作者 Tan Xiaogang Wei Ping Li Liping 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2009年第2期234-240,共7页
To detect higher order polynomial phase signals (HOPPSs), the smoothed-pseudo polynomial Wigner-Ville distribution (SP-PVCVD), an improved version of the polynomial Wigner-Ville distribution (PVCVD), is presente... To detect higher order polynomial phase signals (HOPPSs), the smoothed-pseudo polynomial Wigner-Ville distribution (SP-PVCVD), an improved version of the polynomial Wigner-Ville distribution (PVCVD), is presented using a separable kernel. By adjusting the lengths of the functions in the kernel, the balance between resolution retaining and interference suppressing can be adjusted conveniently. The proposed method with merits of interference terms reduction and noise suppression can provide time frequency representation of better readability and more accurate instantaneous frequency (IF) estimation with higher order SP-PVfVD. The performance of the SP-PWVD is verified by computer simulations. 展开更多
关键词 signal processing polynomial wigner-ville distribution polynomial phase signal instantaneous frequency estimation
下载PDF
SORTING RADAR SIGNAL BASED ON WAVELET CHARACTERISTICS OF WIGNER-VILLE DISTRIBUTION 被引量:4
4
作者 Liang Huadong Han Jianghong 《Journal of Electronics(China)》 2013年第5期454-462,共9页
Common sorting method have low sorting rates and is sensitive to the Signal-to-Noise Ratio(SNR),wavelet characteristics of Wigner-Ville distribution are applied to sort unknown complicated radar signal,high sorting ac... Common sorting method have low sorting rates and is sensitive to the Signal-to-Noise Ratio(SNR),wavelet characteristics of Wigner-Ville distribution are applied to sort unknown complicated radar signal,high sorting accuracy can be got.The Wigner-Ville distribution of received signal is calculated,then it is predigested to two-dimensional characteristics.Using wavelet transformation to extract characteristics from two-dimensional of Wigner-Ville distribution,the best characteristics are selected to be used as sorting parameters.Experiment results demonstrated that the characteristics of eight typical radar emitter signals extracted by this method showed good performance of noise-resistance and clustering at large-scale SNR. 展开更多
关键词 SORTING wigner-ville distribution WAVELET Wavelet packet Normative correlation coefficient
下载PDF
Feature Extraction Method Based on Pseudo-Wigner-Ville Distribution for Rotational Machinery in Variable Operating Conditions 被引量:8
5
作者 WANG Huaqing LIKe +1 位作者 SUN Hao CHEN Peng 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2011年第4期661-668,共8页
In the case of fault diagnosis for roller bearings, the conventional diagnosis approaches by using the time interval of energy impacts in time-frequency distribution or the pass-frequencies are based on the assumption... In the case of fault diagnosis for roller bearings, the conventional diagnosis approaches by using the time interval of energy impacts in time-frequency distribution or the pass-frequencies are based on the assumption that machinery operates under a constant rotational speed. However, when the rotational speed varies in the broader range, the pass-frequencies vary with the change of rotational speed and bearing faults cannot be identified by the interval of impacts. Researches related to automatic diagnosis for rotational machinery in variable operating conditions were quite few. A novel automatic feature extraction method is proposed based on a pseudo-Wigner-Ville distribution (PWVD) and an extraction of symptom parameter (SP). An extraction method for instantaneous feature spectrum is presented using the relative crossing information (RCI) and sequential inference approach, by which the feature spectrum from time-frequency distribution can be automatically, sequentially extracted. The SPs are considered in the frequency domain using the extracted feature spectrum to identify among the conditions of a machine. A method to obtain the synthetic symptom parameter is also proposed by the least squares mapping (LSM) technique for increasing the diagnosis sensitivity of SP. Practical examples of diagnosis for bearings are given in order to verify the effectiveness of the proposed method. The verification results show that the features of bearing faults, such as the outer-race, inner-race and roller element defects have been effectively extracted, and the proposed method can be used for condition diagnosis of a machine under the variable rotational speed. 展开更多
关键词 feature extraction pseudo-wigner-ville distribution variable operating condition sequential diagnosis
下载PDF
A microscopic ancient river channel identification method based on maximum entropy principle and Wigner-Ville Distribution and its application
6
作者 XU Tianji CHENG Bingjie +2 位作者 NIU Shuangchen QIN Zhengye WANG Zhenzhen 《Petroleum Exploration and Development》 CSCD 2021年第6期1354-1366,共13页
In view of the problem of fine characterization of narrow and thin channels,the maximum entropy criterion is used to enhance the focusing characteristics of Wigner-Ville Distribution.On the basis of effectively improv... In view of the problem of fine characterization of narrow and thin channels,the maximum entropy criterion is used to enhance the focusing characteristics of Wigner-Ville Distribution.On the basis of effectively improving the time-frequency resolution of seismic signal,a new method of microscopic ancient river channel identification is established.Based on the principle of the equivalence between the maximum entropy power spectrum and the AR model power spectrum,the prediction error and the autoregression coefficient of AR model are obtained using the Burg algorithm and Levinson-Durbin recurrence rule.Under the condition of the first derivative of autocorrelation function being 0,the Wigner-Ville Distribution of seismic signal is calculated,and the Wigner-Ville Distribution time-frequency power spectrum(MEWVD)is obtained under the maxi-mum entropy criterion of the microscopic ancient river channel.Through analysis of emulational seismic signal and forward numerical simulation signal of narrow thin model,it is found that MEWVD can effectively avoid the interference of cross term of Wigner-Ville Distribution,and obtain more accurate spectral characteristics than STFT and CWT signal analysis methods.It is also proved that the narrow and thin river channels of different scales can be identified effectively by MEWVD of different frequencies.The method is applied to the third member of Jurassic Shaximiao Formation(J2s33-2)gas reservoir of the Zhongji-ang gas field in Sichuan Basin.The spatial information of width and direction of narrow and thin river channels with width less than 500 m and sandstone thickness less than 35 m is accurately identified,providing bases for well deployment and horizontal well fracturing section selection. 展开更多
关键词 maximum entropy principle wigner-ville distribution spectral focusing high resolution SEISMIC fluvial facies narrow and thin ancient channel
下载PDF
Time-Frequency Analysis on Wigner-Ville Distribution of Seismic Signal Based on Time-Frequency Rearrangement 被引量:2
7
作者 Wu Xiao-yang Liu Tian-you 《石油地球物理勘探》 EI CSCD 北大核心 2009年第A02期86-91,共6页
关键词 时频分析方法 时频重排 维格纳分布 地震信号 区域能源 高斯窗函数 火成岩储层 能量分布
下载PDF
Application of spectral decomposition technology in shallow gas detection based on Wigner-Ville distribution
8
作者 CHI Huanzhao LIU Cai +2 位作者 SHAN Xuanlong WANG Dian LU Qi 《Global Geology》 2014年第4期243-246,共4页
Shallow gas is composed of all kinds of shallow buried natural gas resources( < 1500 m) with relatively small reserve for each gas resource. It has some advantages such as shallow burial depth,good physical propert... Shallow gas is composed of all kinds of shallow buried natural gas resources( < 1500 m) with relatively small reserve for each gas resource. It has some advantages such as shallow burial depth,good physical properties and the huge accumulations. Based on the Wigner-Vill distribution,a general spectral decomposition method is applied in the shallow gas detection. Cone-shaped kernel function filtering method is used to suppress cross-terms of the Wigner-Ville distribution,which is tested on field seismic data. Because of shallow gas reservoir has a characteristic that low frequency energy is stronger and high frequency energy is weaker,it indicates the presence of shallow gas successfully. 展开更多
关键词 浅层气藏 维格纳分布 分解技术 应用 检测 天然气资源 基础 物理性能
下载PDF
Nonexistence of cross-term free time-frequency distribution with concentration of Wigner-Ville distribution 被引量:7
9
作者 邹红星 卢旭光 +1 位作者 戴琼海 李衍达 《Science in China(Series F)》 2002年第3期174-180,共7页
Wigner-Ville distribution (WVD) is recognized as being a powerful tool and a nucleus in time-frequency representation (TFR) which gives an excellent time-frequency concentration, and more importantly, has many desirab... Wigner-Ville distribution (WVD) is recognized as being a powerful tool and a nucleus in time-frequency representation (TFR) which gives an excellent time-frequency concentration, and more importantly, has many desirable properties. A major shortcoming of WVD is the inherent cross-term (CT) interference. Although solutions to this problem from the bulk of contributions to the literature concerning TFR are currently available, none has been able to completely eliminate the CT’s in WVD. It is therefore a common belief that if there exists an auxiliary time-frequency distribution (TFD) which has the same auto-terms (AT’s) as that in WVD, but has CT’s with the opposite sign, then, by adding the auxiliary TFD to WVD, an ideal TFD, which preserves the concentration of WVD while annihilating the CT’s, is readily obtained. However, we prove that the auxiliary TFD does not exist. Moreover, it is found that in general, CT free joint distributions with their concentrations close to that of WVD do not exist either. 展开更多
关键词 time-frequency analysis wigner-ville distribution cross-term cancellation.
原文传递
Integrative biogeography: Validating hypotheses of species distribution 被引量:1
10
作者 Zhong-E Hou Shu-Qiang Li 《Zoological Research(Diversity and Conservation)》 2024年第1期86-88,共3页
DEAR EDITOR,Biogeography is a scientific field dedicated to the investigation of the origins and distribution patterns of organisms,as well as predicting future alterations in their geographical distributions(Cox&... DEAR EDITOR,Biogeography is a scientific field dedicated to the investigation of the origins and distribution patterns of organisms,as well as predicting future alterations in their geographical distributions(Cox&Moore,2005).However,the majority of conclusions drawn within the field of biogeography are hypothetical.Rigorous testing of these biogeographic hypotheses remains a considerable challenge.This paper presents the concept of“integrative biogeography”,which emphasizes the experimental testing of biogeographic hypotheses through studies on geological history,as well as biotic and abiotic factors(Figure 1). 展开更多
关键词 BIOGEOGRAPHY distribution DATING
下载PDF
Neural stem cell-derived exosomes promote mitochondrial biogenesis and restore abnormal protein distribution in a mouse model of Alzheimer's disease 被引量:1
11
作者 Bo Li Yujie Chen +10 位作者 Yan Zhou Xuanran Feng Guojun Gu Shuang Han Nianhao Cheng Yawen Sun Yiming Zhang Jiahui Cheng Qi Zhang Wei Zhang Jianhui Liu 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第7期1593-1601,共9页
Mitochondrial dysfunction is a hallmark of Alzheimer’s disease.We previously showed that neural stem cell-derived extracellular vesicles improved mitochondrial function in the cortex of AP P/PS1 mice.Because Alzheime... Mitochondrial dysfunction is a hallmark of Alzheimer’s disease.We previously showed that neural stem cell-derived extracellular vesicles improved mitochondrial function in the cortex of AP P/PS1 mice.Because Alzheimer’s disease affects the entire brain,further research is needed to elucidate alterations in mitochondrial metabolism in the brain as a whole.Here,we investigated the expression of several important mitochondrial biogenesis-related cytokines in multiple brain regions after treatment with neural stem cell-derived exosomes and used a combination of whole brain clearing,immunostaining,and lightsheet imaging to clarify their spatial distribution.Additionally,to clarify whether the sirtuin 1(SIRT1)-related pathway plays a regulatory role in neural stem cell-de rived exosomes interfering with mitochondrial functional changes,we generated a novel nervous system-SIRT1 conditional knoc kout AP P/PS1mouse model.Our findings demonstrate that neural stem cell-de rived exosomes significantly increase SIRT1 levels,enhance the production of mitochondrial biogenesis-related fa ctors,and inhibit astrocyte activation,but do not suppress amyloid-βproduction.Thus,neural stem cell-derived exosomes may be a useful therapeutic strategy for Alzheimer’s disease that activates the SIRT1-PGC1αsignaling pathway and increases NRF1 and COXIV synthesis to improve mitochondrial biogenesis.In addition,we showed that the spatial distribution of mitochondrial biogenesis-related factors is disrupted in Alzheimer’s disease,and that neural stem cell-derived exosome treatment can reverse this effect,indicating that neural stem cell-derived exosomes promote mitochondrial biogenesis. 展开更多
关键词 Alzheimer’s disease mitochondrial biogenesis neural stem cell-derived exosome SIRT1-PGC1α regional brain distribution whole brain clearing and imaging
下载PDF
Influence of Topography on the Distribution and Structure of Woody Plants in the Senegalese Sahel (Sandy Ferlo)
12
作者 Moustapha Bassimbe Sagna Aïssatou Ndong Thiam +5 位作者 Khoudia Niang Oumar Sarr Aly Diallo Sekouna Diatta Daouda Ngom Aliou Guissé 《American Journal of Plant Sciences》 CAS 2024年第1期14-28,共15页
This study describes the floristic composition and structure of a woody stand in the Senegalese Sahel, paying particular attention to the edaphic factors of its floristic composition. A stratified inventory considerin... This study describes the floristic composition and structure of a woody stand in the Senegalese Sahel, paying particular attention to the edaphic factors of its floristic composition. A stratified inventory considering the different relief units was adopted. Woody vegetation was surveyed using a dendrometric approach. The results obtained show that the flora is dominated by a few species adapted to drought, such as Balanites aegyptiaca (L.) Del., Calotropis procera Ait. and Boscia senegalensis (Pers.). The distribution of this flora and the structure of the ligneous plants are linked to the topography. In the lowlands, the flora is more diversified and the ligneous plants reach their optimum level of development compared with the higher relief areas. In the lowlands, there are a few woody species which, in the past, were indicative of better climatic conditions. These are Anogeissus leiocarpus (DC.), Commiphora africana (A. Rich.), Feretia apodanthera Del., Loeseneriella africana (A. Smith), Mitragyna inermis (Willd.) and Sclerocarya birrea (A. Rich). It is important that their reintroduction into reforestation projects takes account of their edaphic preference. 展开更多
关键词 Woody Plants distribution TOPOGRAPHY Ferlo Senegal
下载PDF
Boosting Adversarial Training with Learnable Distribution
13
作者 Kai Chen Jinwei Wang +2 位作者 James Msughter Adeke Guangjie Liu Yuewei Dai 《Computers, Materials & Continua》 SCIE EI 2024年第3期3247-3265,共19页
In recent years,various adversarial defense methods have been proposed to improve the robustness of deep neural networks.Adversarial training is one of the most potent methods to defend against adversarial attacks.How... In recent years,various adversarial defense methods have been proposed to improve the robustness of deep neural networks.Adversarial training is one of the most potent methods to defend against adversarial attacks.However,the difference in the feature space between natural and adversarial examples hinders the accuracy and robustness of the model in adversarial training.This paper proposes a learnable distribution adversarial training method,aiming to construct the same distribution for training data utilizing the Gaussian mixture model.The distribution centroid is built to classify samples and constrain the distribution of the sample features.The natural and adversarial examples are pushed to the same distribution centroid to improve the accuracy and robustness of the model.The proposed method generates adversarial examples to close the distribution gap between the natural and adversarial examples through an attack algorithm explicitly designed for adversarial training.This algorithm gradually increases the accuracy and robustness of the model by scaling perturbation.Finally,the proposed method outputs the predicted labels and the distance between the sample and the distribution centroid.The distribution characteristics of the samples can be utilized to detect adversarial cases that can potentially evade the model defense.The effectiveness of the proposed method is demonstrated through comprehensive experiments. 展开更多
关键词 Adversarial training feature space learnable distribution distribution centroid
下载PDF
Diversity of Orchids in Terms of Their Distribution, Uses and Conservation in Annapurna Conservation Area of Nepal
14
作者 Babu Lal Tiruwa Basu Dev Neupane +2 位作者 Rabin Kadariya Chiranjibi Prasad Pokheral Bijaya Pant 《American Journal of Plant Sciences》 CAS 2024年第6期422-440,共19页
The Annapurna Conservation Area (ACA), the first conservation area and the largest protected area (PA) in Nepal, is incredibly rich in biodiversity. Notwithstanding this, orchids in the ACA have not been explored enou... The Annapurna Conservation Area (ACA), the first conservation area and the largest protected area (PA) in Nepal, is incredibly rich in biodiversity. Notwithstanding this, orchids in the ACA have not been explored enough yet thus making the need for ambitious research to be carried out. Previous study only included 81 species of orchids within ACA. This study aims to update the record of species and genera richness in the ACA. In total 198 species of orchids, belonging to 67 genera (40% and 62% of the total recorded orchid species and genera in Nepal) has been recorded in ACA. This represents an increase of 144% in species and 56% in genera over the previous data. Out of the 198 species, 99 were epiphytes, 6 were holomycotrophic and 93 were terrestrial. Among the 67 genera, Bulbophyllum (17) species were dominant, followed by Dendrobium (16), Herminium (10), Coelogyne, Plantanthera (9 each), Eria, Habenaria, Oberonia (8 each), Calanthe (7), and Liparis (6). Fifty-six species were found to be ornamentally significant and 85 species medicinally significant. 展开更多
关键词 ORCHIDS Annapurna Conservation Area DIVERSITY distribution USES
下载PDF
Simulation of Haloxylon Ammodendron Stand Basic Diameter Structure Based on Fuzzy Distribution Function
15
作者 Shaohua Wang Chuanqiang Liu Ting Yang 《Agricultural Sciences》 2024年第1期132-145,共14页
Based on the investigation data of 12 Haloxylon ammodendron plots in the south edge of Gurbantunggut Desert, Fuzzy distribution was introduced into the study of Haloxylon ammodendron base diameter structure fitting ac... Based on the investigation data of 12 Haloxylon ammodendron plots in the south edge of Gurbantunggut Desert, Fuzzy distribution was introduced into the study of Haloxylon ammodendron base diameter structure fitting according to the consistency between the characteristics of Fuzzy distribution function and the distribution series of cumulative percentage of stand base diameter, and the fitting precision and effect of Fuzzy distribution function were discussed. The root mean square error RMSE and determination coefficient R<sup>2</sup> values showed that Fuzzy-Γ<sub>1</sub>, Fuzzy-Γ<sub>2</sub>, Fuzzy-Γ<sub>3</sub>, Fuzzy-Γ<sub>4</sub> had good fitting performance, among which Fuzzy-Γ<sub>1</sub> had relatively high fitting precision, and its parameters were closely related to stand age and density, Fuzzy-Γ<sub>2</sub> distribution function was the second, and Fuzzy-Γ<sub>4</sub> distribution function had the worst fitting effect. By introducing a parameter c from the similarity of four distribution function formulas, a generalized Fuzzy distribution function Fuzzy-Γ<sub>5</sub> is obtained. This function shows the highest fitting accuracy. Most of the values of parameter c are near 1 or 2, which shows that the diameter distribution is mainly approximate to Fuzzy-Γ<sub>1</sub> and Fuzzy-Γ<sub>2</sub>. 展开更多
关键词 Fuzzy distribution Function Haloxylon Ammodendron Base Diameter distribution Stand Factor
下载PDF
Heterogeneous population distribution enhances resistance to wheat lodging by optimizing the light environment
16
作者 Yibo Hu Feng Qin +6 位作者 Zhen Wu Xiaoqin Wang Xiaolong Ren Zhikuan Jia Zhenlin Wang Xiaoguang Chen Tie Cai 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第7期2211-2226,共16页
Lodging is still the key factor that limits continuous increases in wheat yields today,because the mechanical strength of culms is reduced due to low-light stress in populations under high-yield cultivation.The mechan... Lodging is still the key factor that limits continuous increases in wheat yields today,because the mechanical strength of culms is reduced due to low-light stress in populations under high-yield cultivation.The mechanical properties of the culm are mainly determined by lignin,which is affected by the light environment.However,little is known about whether the light environment can be sufficiently improved by changing the population distribution to inhibit culm lodging.Therefore,in this study,we used the wheat cultivar“Xinong 979”to establish a low-density homogeneous distribution treatment(LD),high-density homogeneous distribution treatment(HD),and high-density heterogeneous distribution treatment(HD-h)to study the regulatory effects and mechanism responsible for differences in the lodging resistance of wheat culms under different population distributions.Compared with LD,HD significantly reduced the light transmittance in the middle and basal layers of the canopy,the net photosynthetic rate in the middle and lower leaves of plants,the accumulation of lignin in the culm,and the breaking resistance of the culm,and thus the lodging index values increased significantly,with lodging rates of 67.5%in 2020–2021 and 59.3%in 2021–2022.Under HD-h,the light transmittance and other indicators in the middle and basal canopy layers were significantly higher than those under HD,and the lodging index decreased to the point that no lodging occurred.Compared with LD,the activities of phenylalanine ammonia-Lyase(PAL),4-coumarate:coenzyme A ligase(4CL),catecholO-methyltransferase(COMT),and cinnamyl-alcohol dehydrogenase(CAD)in the lignin synthesis pathway were significantly reduced in the culms under HD during the critical period for culm formation,and the relative expression levels of TaPAL,Ta4CL,TaCOMT,and TaCAD were significantly downregulated.However,the activities of lignin synthesis-related enzymes and their gene expression levels were significantly increased under HD-h compared with HD.A partial least squares path modeling analysis found significant positive effects between the canopy light environment,the photosynthetic capacity of the middle and lower leaves of plants,lignin synthesis and accumulation,and lodging resistance in the culms.Thus,under conventional high-density planting,the risk of wheat lodging was significantly higher.Accordingly,the canopy light environment can be optimized by changing the heterogeneity of the population distribution to improve the photosynthetic capacity of the middle and lower leaves of plants,promote lignin accumulation in the culm,and enhance lodging resistance in wheat.These findings provide a basis for understanding the mechanism responsible for the lower mechanical strength of the culm under high-yield wheat cultivation,and a theoretical basis and for developing technical measures to enhance lodging resistance. 展开更多
关键词 canopy light environment LIGNIN LODGING population distribution WHEAT
下载PDF
Red cell distribution width/platelet ratio estimates the 3-year risk of decompensation in Metabolic Dysfunction-Associated Steatotic Liver Disease-induced cirrhosis
17
作者 Marcello Dallio Mario Romeo +8 位作者 Paolo Vaia Salvatore Auletta Simone Mammone Marina Cipullo Luigi Sapio Angela Ragone Marco Niosi Silvio Naviglio Alessandro Federico 《World Journal of Gastroenterology》 SCIE CAS 2024年第7期685-704,共20页
BACKGROUND For compensated advanced chronic liver disease(cACLD)patients,the first decompensation represents a dramatically worsening prognostic event.Based on the first decompensation event(DE),the transition to deco... BACKGROUND For compensated advanced chronic liver disease(cACLD)patients,the first decompensation represents a dramatically worsening prognostic event.Based on the first decompensation event(DE),the transition to decompensated advanced chronic liver disease(dACLD)can occur through two modalities referred to as acute decompensation(AD)and non-AD(NAD),respectively.Clinically Significant Portal Hypertension(CSPH)is considered the strongest predictor of decompensation in these patients.However,due to its invasiveness and costs,CSPH is almost never evaluated in clinical practice.Therefore,recognizing noninvasively predicting tools still have more appeal across healthcare systems.The red cell distribution width to platelet ratio(RPR)has been reported to be an indicator of hepatic fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease(MASLD).However,its predictive role for the decompensation has never been explored.AIM In this observational study,we investigated the clinical usage of RPR in predicting DEs in MASLD-related cACLD patients.METHODS Fourty controls and 150 MASLD-cACLD patients were consecutively enrolled and followed up(FUP)semiannually for 3 years.At baseline,biochemical,clinical,and Liver Stiffness Measurement(LSM),Child-Pugh(CP),Model for End-Stage Liver Disease(MELD),aspartate aminotransferase/platelet count ratio index(APRI),Fibrosis-4(FIB-4),Albumin-Bilirubin(ALBI),ALBI-FIB-4,and RPR were collected.During FUP,DEs(timing and modaities)were recorded.CSPH was assessed at the baseline and on DE occurrence according to the available Clinical Practice Guidelines.RESULTS Of 150 MASLD-related cACLD patients,43(28.6%)progressed to dACLD at a median time of 28.9 months(29 NAD and 14 AD).Baseline RPR values were significantly higher in cACLD in comparison to controls,as well as MELD,CP,APRI,FIB-4,ALBI,ALBI-FIB-4,and LSM in dACLD-progressing compared to cACLD individuals[all P<0.0001,except for FIB-4(P:0.007)and ALBI(P:0.011)].Receiving operator curve analysis revealed RPR>0.472 and>0.894 as the best cut-offs in the prediction respectively of 3-year first DE,as well as its superiority compared to the other non-invasive tools examined.RPR(P:0.02)and the presence of baseline-CSPH(P:0.04)were significantly and independently associated with the DE.Patients presenting baseline-CSPH and RPR>0.472 showed higher risk of decompensation(P:0.0023).CONCLUSION Altogether these findings suggest the RPR as a valid and potentially applicable non-invasive tool in the prediction of timing and modalities of decompensation in MASLD-related cACLD patients. 展开更多
关键词 Liver cirrhosis Red blood cell distribution width Red blood cell distribution width to platelet ratio Translational Medicine Prognostic biomarker
下载PDF
Prevalence and ecological factors affecting the distribution of plant-parasitic nematodes in Prunus groves in Spain
18
作者 Ilenia Clavero-Camacho Antonio Archidona-Yuste +2 位作者 Carolina Cantalapiedra-Navarrete Pablo Castillo Juan Emilio Palomares-Rius 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第2期566-589,共24页
A wide survey was conducted to study plant-parasitic nematodes(PPNs)associated with Prunus groves in Spain.This research aimed to determine the prevalence and distribution of PPNs in Prunus groves,as well as the influ... A wide survey was conducted to study plant-parasitic nematodes(PPNs)associated with Prunus groves in Spain.This research aimed to determine the prevalence and distribution of PPNs in Prunus groves,as well as the influence of explanatory variables describing soil,climate and agricultural management in structuring the variation of PPNs community composition.A total of 218 sampling sites were surveyed and 84 PPN species belonging to 32 genera were identified based of an integrative taxonomic approach.PPN species considered as potential limiting factors in Prunus production,such as Meloidogyne arenaria,M.incognita,M.javanica,Pratylenchus penetrans and P.vulnus,were identified in this survey.Seven soil physico-chemical(C,Mg,N,Na,OM,P,pH and clay,loamy sand and sandy loam texture classes),four climate(Bio04,Bio05,Bio13 and Bio14)and four agricultural management variables(grove-use history less than 10 years,irrigation,apricot seedling rootstock,and Montclar rootstock)were identified as the most influential variables driving spatial patterns of PPNs communities.In particular,younger plantations showed higher values for species richness and diversity indices than groves cultivated for more than 20 years with Prunus spp.Our study increases the knowledge of the distribution and prevalence of PPNs associated with Prunus rhizosphere,as well as on the influence of explanatory variables driving the spatial structure PPNs communities,which has important implications for the successful design of sustainable management strategies in the future in this agricultural system. 展开更多
关键词 nematodes MELOIDOGYNE PRATYLENCHUS Paratylenchus ROOTSTOCK distribution soil grove-use ALMOND peach
下载PDF
The Uptake and Distribution Evidence of Nano-and Microplastics in vivo after a Single High Dose of Oral Exposure
19
作者 HONG Tao SUN Wei +9 位作者 DENG Yuan LYU Jian Da JIN Cui Hong BAI Ying Long NA Jun ZHANG Rui GAO Yuan PAN Guo Wei YANG Zuo Sen YAN Ling Jun 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2024年第1期31-41,共11页
Objective Tissue uptake and distribution of nano-/microplastics was studied at a single high dose by gavage in vivo.Methods Fluorescent microspheres(100 nm,3μm,and 10μm)were given once at a dose of 200 mg/(kg∙body w... Objective Tissue uptake and distribution of nano-/microplastics was studied at a single high dose by gavage in vivo.Methods Fluorescent microspheres(100 nm,3μm,and 10μm)were given once at a dose of 200 mg/(kg∙body weight).The fluorescence intensity(FI)in observed organs was measured using the IVIS Spectrum at 0.5,1,2,and 4 h after administration.Histopathology was performed to corroborate these findings.Results In the 100 nm group,the FI of the stomach and small intestine were highest at 0.5 h,and the FI of the large intestine,excrement,lung,kidney,liver,and skeletal muscles were highest at 4 h compared with the control group(P<0.05).In the 3μm group,the FI only increased in the lung at 2 h(P<0.05).In the 10μm group,the FI increased in the large intestine and excrement at 2 h,and in the kidney at 4 h(P<0.05).The presence of nano-/microplastics in tissues was further verified by histopathology.The peak time of nanoplastic absorption in blood was confirmed.Conclusion Nanoplastics translocated rapidly to observed organs/tissues through blood circulation;however,only small amounts of MPs could penetrate the organs. 展开更多
关键词 Microplastics Nanoplastics IVIS Spectrum small-animal imaging system Tissue distribution BLOOD
下载PDF
Tuning mechanical behaviors of highly entangled hydrogels with the random distribution of mobile entanglements
20
作者 Jinlong LIU Di LU Bin CHEN 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第2期277-294,共18页
Highly entangled hydrogels exhibit excellent mechanical properties,including high toughness,high stretchability,and low hysteresis.By considering the evolution of randomly distributed entanglements within the polymer ... Highly entangled hydrogels exhibit excellent mechanical properties,including high toughness,high stretchability,and low hysteresis.By considering the evolution of randomly distributed entanglements within the polymer network upon mechanical stretches,we develop a constitutive theory to describe the large stretch behaviors of these hydrogels.In the theory,we utilize a representative volume element(RVE)in the shape of a cube,within which there exists an averaged chain segment along each edge and a mobile entanglement at each corner.By employing an explicit method,we decouple the elasticity of the hydrogels from the sliding motion of their entanglements,and derive the stress-stretch relations for these hydrogels.The present theoretical analysis is in agreement with experiment,and highlights the significant influence of the entanglement distribution within the hydrogels on their elasticity.We also implement the present developed constitutive theory into a commercial finite element software,and the subsequent simulations demonstrate that the exact distribution of entanglements strongly affects the mechanical behaviors of the structures of these hydrogels.Overall,the present theory provides valuable insights into the deformation mechanism of highly entangled hydrogels,and can aid in the design of these hydrogels with enhanced performance. 展开更多
关键词 highly entangled hydrogel constitutive theory ENTANGLEMENT gamma distribution
下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部