Ⅰ. INTRODUCTION von Willebrand factor (vWF), a large adhesive plasma glycoprotein, plays a central role in the adhesion of platelets to injured vessel wall and also serves as a carrier protein for coagulant factor Ⅷ...Ⅰ. INTRODUCTION von Willebrand factor (vWF), a large adhesive plasma glycoprotein, plays a central role in the adhesion of platelets to injured vessel wall and also serves as a carrier protein for coagulant factor Ⅷ (FⅧ), stabilizing the activity of FⅧ in plasma. The vWF gene of 178 kb in length is localized at chromosome 12p12-pter. The gene contains 52展开更多
基金Project supported by the National Natural Science Foundation of China and the Fund for Excellent Young University Teachers of the State Education Commission (FEYUT, SEDC, China).
文摘Ⅰ. INTRODUCTION von Willebrand factor (vWF), a large adhesive plasma glycoprotein, plays a central role in the adhesion of platelets to injured vessel wall and also serves as a carrier protein for coagulant factor Ⅷ (FⅧ), stabilizing the activity of FⅧ in plasma. The vWF gene of 178 kb in length is localized at chromosome 12p12-pter. The gene contains 52
