Background The World Health Organization End TB Strategy meant that compared with 2015 baseline,the reduction in pulmonary tuberculosis(PTB)incidence should be 20 and 50%in 2020 and 2025,respectively.The case number o...Background The World Health Organization End TB Strategy meant that compared with 2015 baseline,the reduction in pulmonary tuberculosis(PTB)incidence should be 20 and 50%in 2020 and 2025,respectively.The case number of PTB in China accounted for 9%of the global total in 2018,which ranked the second high in the world.From 2007 to 2019,854672 active PTB cases were registered and treated in Henan Province,China.This study was to assess whether the WHO milestones could be achieved in Henan Province.Methods The active PTB numbers in Henan Province from 2007 to 2019,registered in Chinese Tuberculosis Information Management System were analyzed to predict the active PTB registration rates in 2020 and 2025,which is conductive to early response measures to ensure the achievement of the WHO milestones.The time series model was created by monthly active PTB registration rates from 2007 to 2016,and the optimal model was verified by data from 2017 to 2019.The Ljung-Box Q statistic was used to evaluate the model.The statistically significant level isα=0.05.Monthly active PTB registration rates and 95%confidence interval(CI)from 2020 to 2025 were predicted.Results High active PTB registration rates in March,April,May and June showed the seasonal variations.The exponential smoothing winter’s multiplication model was selected as the best-fitting model.The predicted values were approximately consistent with the observed ones from 2017 to 2019.The annual active PTB registration rates were predicted as 49.1(95%CI:36.2–62.0)per 100000 population and 34.4(95%CI:18.6–50.2)per 100000 population in 2020 and 2025,respectively.Compared with the active PTB registration rate in 2015,the reduction will reach 23.7%(95%CI,3.2–44.1%)and 46.8%(95%CI,21.4–72.1%)in 2020 and 2025,respectively.Conclusions The high active PTB registration rates in spring and early summer indicate that high risk of tuberculosis infection in late autumn and winter in Henan Province.Without regard to the CI,the first milestone of WHO End TB Strategy in 2020 will be achieved.However,the second milestone in 2025 will not be easily achieved unless there are early response measures in Henan Province,China.展开更多
The main aim of this research work is to be aware of the road traffic accident scenario, injurious effects and pattern in Bangladesh. Moreover we are interested to forecast the magnitude of road traffic accidents for ...The main aim of this research work is to be aware of the road traffic accident scenario, injurious effects and pattern in Bangladesh. Moreover we are interested to forecast the magnitude of road traffic accidents for the future so that decision makers can make appropriate decision for precaution. This study also provides an assessment of road traffic accidents in Bangladesh and its impact based on data collected for the period of 1971 to 2017. In this study we have tried to pick up the main reasons of road accidents and to observe the tremendous situation. The study observed that the general trends of road traffic accident (RTA), deaths and injuries reveal that the number of RTA, deaths and injuries increased gradually with little fluctuations form 1971 to 2007 and after 2007 there is a slow decreasing trend. Although the number of RTA and deaths observed decreasing trend in recent years, the ratio of number of deaths to number of accident increased significantly. The rate of register vehicles per 10,000 people increased moderately throughout the period but a sharp increment is exhibited from 2009. Highest percentage of RTA (34%) and deaths is due to RTA (32%) in Dhaka division while the lowest percentage of RTA (4%) in Barisal and Sylhet divisions and deaths is due to RTA (3%) in Barisal division. It is noticed that the maximum number of injuries occurred between ages 21 and 30 while the maximum number of deaths occurred between ages 11 and 30. Most of the RTA and deaths due to RTA are caused by run over by vehicles and head to head collision. The severity of occurring road accident and number of deaths are higher during the festive periods because of involving higher frequency of traveling than usual. The time plot shows that the graph maintains a decreasing movement from 2012 to 2015 but increases from 2015 to 2017. In the research an additive time series model approach is applied. It included the estimation of trend, seasonal variation and random variation using triple exponential smoothing method. We performed forecasting of RTA eliminating seasonal impact for the next three consecutive years (2018-2020) with 95% confidence interval using Holt-Winters exponential technique.展开更多
文摘Background The World Health Organization End TB Strategy meant that compared with 2015 baseline,the reduction in pulmonary tuberculosis(PTB)incidence should be 20 and 50%in 2020 and 2025,respectively.The case number of PTB in China accounted for 9%of the global total in 2018,which ranked the second high in the world.From 2007 to 2019,854672 active PTB cases were registered and treated in Henan Province,China.This study was to assess whether the WHO milestones could be achieved in Henan Province.Methods The active PTB numbers in Henan Province from 2007 to 2019,registered in Chinese Tuberculosis Information Management System were analyzed to predict the active PTB registration rates in 2020 and 2025,which is conductive to early response measures to ensure the achievement of the WHO milestones.The time series model was created by monthly active PTB registration rates from 2007 to 2016,and the optimal model was verified by data from 2017 to 2019.The Ljung-Box Q statistic was used to evaluate the model.The statistically significant level isα=0.05.Monthly active PTB registration rates and 95%confidence interval(CI)from 2020 to 2025 were predicted.Results High active PTB registration rates in March,April,May and June showed the seasonal variations.The exponential smoothing winter’s multiplication model was selected as the best-fitting model.The predicted values were approximately consistent with the observed ones from 2017 to 2019.The annual active PTB registration rates were predicted as 49.1(95%CI:36.2–62.0)per 100000 population and 34.4(95%CI:18.6–50.2)per 100000 population in 2020 and 2025,respectively.Compared with the active PTB registration rate in 2015,the reduction will reach 23.7%(95%CI,3.2–44.1%)and 46.8%(95%CI,21.4–72.1%)in 2020 and 2025,respectively.Conclusions The high active PTB registration rates in spring and early summer indicate that high risk of tuberculosis infection in late autumn and winter in Henan Province.Without regard to the CI,the first milestone of WHO End TB Strategy in 2020 will be achieved.However,the second milestone in 2025 will not be easily achieved unless there are early response measures in Henan Province,China.
文摘The main aim of this research work is to be aware of the road traffic accident scenario, injurious effects and pattern in Bangladesh. Moreover we are interested to forecast the magnitude of road traffic accidents for the future so that decision makers can make appropriate decision for precaution. This study also provides an assessment of road traffic accidents in Bangladesh and its impact based on data collected for the period of 1971 to 2017. In this study we have tried to pick up the main reasons of road accidents and to observe the tremendous situation. The study observed that the general trends of road traffic accident (RTA), deaths and injuries reveal that the number of RTA, deaths and injuries increased gradually with little fluctuations form 1971 to 2007 and after 2007 there is a slow decreasing trend. Although the number of RTA and deaths observed decreasing trend in recent years, the ratio of number of deaths to number of accident increased significantly. The rate of register vehicles per 10,000 people increased moderately throughout the period but a sharp increment is exhibited from 2009. Highest percentage of RTA (34%) and deaths is due to RTA (32%) in Dhaka division while the lowest percentage of RTA (4%) in Barisal and Sylhet divisions and deaths is due to RTA (3%) in Barisal division. It is noticed that the maximum number of injuries occurred between ages 21 and 30 while the maximum number of deaths occurred between ages 11 and 30. Most of the RTA and deaths due to RTA are caused by run over by vehicles and head to head collision. The severity of occurring road accident and number of deaths are higher during the festive periods because of involving higher frequency of traveling than usual. The time plot shows that the graph maintains a decreasing movement from 2012 to 2015 but increases from 2015 to 2017. In the research an additive time series model approach is applied. It included the estimation of trend, seasonal variation and random variation using triple exponential smoothing method. We performed forecasting of RTA eliminating seasonal impact for the next three consecutive years (2018-2020) with 95% confidence interval using Holt-Winters exponential technique.
