Background:To investigate the factors associating with the cumulative clinical pregnancy outcome of in vitro fertilization-embryo transfer(IVF-ET)in women aged 35 years and older with normal ovarian reserve.Methods:A ...Background:To investigate the factors associating with the cumulative clinical pregnancy outcome of in vitro fertilization-embryo transfer(IVF-ET)in women aged 35 years and older with normal ovarian reserve.Methods:A total of 358 patients undergoing IVF-ET at the Department of Reproductive Medicine,the First Affiliated Hospital of Xinjiang Medical University between January 2014 and June 2016 were analyzed by the Kaplan-Meier method and Cox proportional hazards model.Results:The probability of pregnancy in women 35-37 years of age and 38-40 years of age was 75.9%(95%confidence interval[CI]:75.1%-76.7%)and 66.9%(95%CI:65.6%-68.2%),respectively,and it was 37.8%(95%CI:34.7%-41.1%)in women aged 40 years and older.Univariate analysis(hazard ratio[HR]:2.50,95%CI:1.647-3.774)and multivariate analysis(HR:2.17,95%CI:1.427-3.268)showed a correlation between the number of retrieved oocytes and successful pregnancy.Conclusions:The number of retrieved oocytes plays a key role in the pregnancy outcome of women aged 35 years and older with normal ovarian reserve.We recommend the number of retrieved oocytes be increased for women aged 35 years and older with normal ovarian reserve.展开更多
目的分析湖南省40岁及以上女性艾滋病自愿咨询检测(voluntary counseling and testing,VCT)意愿的现状及相关影响因素。方法采用分层整群抽样方法,选择湖南省城乡958名40岁及以上女性,采用一般资料问卷、接受VCT服务意愿及相关知识问卷...目的分析湖南省40岁及以上女性艾滋病自愿咨询检测(voluntary counseling and testing,VCT)意愿的现状及相关影响因素。方法采用分层整群抽样方法,选择湖南省城乡958名40岁及以上女性,采用一般资料问卷、接受VCT服务意愿及相关知识问卷和HIV/AIDS相关知识、态度和行为问卷开展调查,采用单因素Logistic回归模型和多因素二项Logistic回归模型,分析40岁及以上女性愿意接受VCT服务的影响因素。结果958名调查对象中,52.4%(502人)的女性愿意接受VCT服务,VCT相关知识得分为(4.35±2.49)分,HIV/AIDS相关知识知晓率较低为51.7%;单因素分析显示,年龄(OR=0.926,95%CI:0.911~0.942)、居住地(OR=1.321,95%CI:1.025~1.704)、感知HIV感染风险(OR=2.483,95%CI:1.809~3.409)和HIV/AIDS相关知识(OR=1.136,95%CI:1.100~1.173)是影响女性接受VCT服务意愿的主要因素(P<0.05);多因素分析显示,年龄(OR=0.976,95%CI:0.954~0.999)、是否接受过VCT服务(OR=0.087,95%CI:0.042~0.177)、现在有无性生活(OR=1.697,95%CI:1.120~2.572)、感知HIV感染风险(OR=1.601,95%CI:1.114~2.302)、VCT相关知识得分(OR=1.102,95%CI:1.026~1.183)和HIV/AIDS相关知识得分(OR=1.095,95%CI:1.050~1.143)是女性愿意接受VCT服务的影响因素(P<0.05)。结论40岁及以上女性愿意接受VCT服务处于中等水平;应针对中老年女性人群普及VCT服务,提高其接受VCT服务的意愿,需要时能积极寻求VCT服务,预防艾滋病在此人群中进一步传播。展开更多
文摘Background:To investigate the factors associating with the cumulative clinical pregnancy outcome of in vitro fertilization-embryo transfer(IVF-ET)in women aged 35 years and older with normal ovarian reserve.Methods:A total of 358 patients undergoing IVF-ET at the Department of Reproductive Medicine,the First Affiliated Hospital of Xinjiang Medical University between January 2014 and June 2016 were analyzed by the Kaplan-Meier method and Cox proportional hazards model.Results:The probability of pregnancy in women 35-37 years of age and 38-40 years of age was 75.9%(95%confidence interval[CI]:75.1%-76.7%)and 66.9%(95%CI:65.6%-68.2%),respectively,and it was 37.8%(95%CI:34.7%-41.1%)in women aged 40 years and older.Univariate analysis(hazard ratio[HR]:2.50,95%CI:1.647-3.774)and multivariate analysis(HR:2.17,95%CI:1.427-3.268)showed a correlation between the number of retrieved oocytes and successful pregnancy.Conclusions:The number of retrieved oocytes plays a key role in the pregnancy outcome of women aged 35 years and older with normal ovarian reserve.We recommend the number of retrieved oocytes be increased for women aged 35 years and older with normal ovarian reserve.
文摘目的分析湖南省40岁及以上女性艾滋病自愿咨询检测(voluntary counseling and testing,VCT)意愿的现状及相关影响因素。方法采用分层整群抽样方法,选择湖南省城乡958名40岁及以上女性,采用一般资料问卷、接受VCT服务意愿及相关知识问卷和HIV/AIDS相关知识、态度和行为问卷开展调查,采用单因素Logistic回归模型和多因素二项Logistic回归模型,分析40岁及以上女性愿意接受VCT服务的影响因素。结果958名调查对象中,52.4%(502人)的女性愿意接受VCT服务,VCT相关知识得分为(4.35±2.49)分,HIV/AIDS相关知识知晓率较低为51.7%;单因素分析显示,年龄(OR=0.926,95%CI:0.911~0.942)、居住地(OR=1.321,95%CI:1.025~1.704)、感知HIV感染风险(OR=2.483,95%CI:1.809~3.409)和HIV/AIDS相关知识(OR=1.136,95%CI:1.100~1.173)是影响女性接受VCT服务意愿的主要因素(P<0.05);多因素分析显示,年龄(OR=0.976,95%CI:0.954~0.999)、是否接受过VCT服务(OR=0.087,95%CI:0.042~0.177)、现在有无性生活(OR=1.697,95%CI:1.120~2.572)、感知HIV感染风险(OR=1.601,95%CI:1.114~2.302)、VCT相关知识得分(OR=1.102,95%CI:1.026~1.183)和HIV/AIDS相关知识得分(OR=1.095,95%CI:1.050~1.143)是女性愿意接受VCT服务的影响因素(P<0.05)。结论40岁及以上女性愿意接受VCT服务处于中等水平;应针对中老年女性人群普及VCT服务,提高其接受VCT服务的意愿,需要时能积极寻求VCT服务,预防艾滋病在此人群中进一步传播。
