Objective To observe the value of artificial intelligence(AI)models based on non-contrast chest CT for measuring bone mineral density(BMD).Methods Totally 380 subjects who underwent both non-contrast chest CT and quan...Objective To observe the value of artificial intelligence(AI)models based on non-contrast chest CT for measuring bone mineral density(BMD).Methods Totally 380 subjects who underwent both non-contrast chest CT and quantitative CT(QCT)BMD examination were retrospectively enrolled and divided into training set(n=304)and test set(n=76)at a ratio of 8∶2.The mean BMD of L1—L3 vertebrae were measured based on QCT.Spongy bones of T5—T10 vertebrae were segmented as ROI,radiomics(Rad)features were extracted,and machine learning(ML),Rad and deep learning(DL)models were constructed for classification of osteoporosis(OP)and evaluating BMD,respectively.Receiver operating characteristic curves were drawn,and area under the curves(AUC)were calculated to evaluate the efficacy of each model for classification of OP.Bland-Altman analysis and Pearson correlation analysis were performed to explore the consistency and correlation of each model with QCT for measuring BMD.Results Among ML and Rad models,ML Bagging-OP and Rad Bagging-OP had the best performances for classification of OP.In test set,AUC of ML Bagging-OP,Rad Bagging-OP and DL OP for classification of OP was 0.943,0.944 and 0.947,respectively,with no significant difference(all P>0.05).BMD obtained with all the above models had good consistency with those measured with QCT(most of the differences were within the range of Ax-G±1.96 s),which were highly positively correlated(r=0.910—0.974,all P<0.001).Conclusion AI models based on non-contrast chest CT had high efficacy for classification of OP,and good consistency of BMD measurements were found between AI models and QCT.展开更多
Objective To observe the value of self-supervised deep learning artificial intelligence(AI)noise reduction technology based on the nearest adjacent layer applicated in ultra-low dose CT(ULDCT)for urinary calculi.Metho...Objective To observe the value of self-supervised deep learning artificial intelligence(AI)noise reduction technology based on the nearest adjacent layer applicated in ultra-low dose CT(ULDCT)for urinary calculi.Methods Eighty-eight urinary calculi patients were prospectively enrolled.Low dose CT(LDCT)and ULDCT scanning were performed,and the effective dose(ED)of each scanning protocol were calculated.The patients were then randomly divided into training set(n=75)and test set(n=13),and a self-supervised deep learning AI noise reduction system based on the nearest adjacent layer constructed with ULDCT images in training set was used for reducing noise of ULDCT images in test set.In test set,the quality of ULDCT images before and after AI noise reduction were compared with LDCT images,i.e.Blind/Referenceless Image Spatial Quality Evaluator(BRISQUE)scores,image noise(SD ROI)and signal-to-noise ratio(SNR).Results The tube current,the volume CT dose index and the dose length product of abdominal ULDCT scanning protocol were all lower compared with those of LDCT scanning protocol(all P<0.05),with a decrease of ED for approximately 82.66%.For 13 patients with urinary calculi in test set,BRISQUE score showed that the quality level of ULDCT images before AI noise reduction reached 54.42%level but raised to 95.76%level of LDCT images after AI noise reduction.Both ULDCT images after AI noise reduction and LDCT images had lower SD ROI and higher SNR than ULDCT images before AI noise reduction(all adjusted P<0.05),whereas no significant difference was found between the former two(both adjusted P>0.05).Conclusion Self-supervised learning AI noise reduction technology based on the nearest adjacent layer could effectively reduce noise and improve image quality of urinary calculi ULDCT images,being conducive for clinical application of ULDCT.展开更多
A chest radiology scan can significantly aid the early diagnosis and management of COVID-19 since the virus attacks the lungs.Chest X-ray(CXR)gained much interest after the COVID-19 outbreak thanks to its rapid imagin...A chest radiology scan can significantly aid the early diagnosis and management of COVID-19 since the virus attacks the lungs.Chest X-ray(CXR)gained much interest after the COVID-19 outbreak thanks to its rapid imaging time,widespread availability,low cost,and portability.In radiological investigations,computer-aided diagnostic tools are implemented to reduce intra-and inter-observer variability.Using lately industrialized Artificial Intelligence(AI)algorithms and radiological techniques to diagnose and classify disease is advantageous.The current study develops an automatic identification and classification model for CXR pictures using Gaussian Fil-tering based Optimized Synergic Deep Learning using Remora Optimization Algorithm(GF-OSDL-ROA).This method is inclusive of preprocessing and classification based on optimization.The data is preprocessed using Gaussian filtering(GF)to remove any extraneous noise from the image’s edges.Then,the OSDL model is applied to classify the CXRs under different severity levels based on CXR data.The learning rate of OSDL is optimized with the help of ROA for COVID-19 diagnosis showing the novelty of the work.OSDL model,applied in this study,was validated using the COVID-19 dataset.The experiments were conducted upon the proposed OSDL model,which achieved a classification accuracy of 99.83%,while the current Convolutional Neural Network achieved less classification accuracy,i.e.,98.14%.展开更多
Sensitive and reliable X-ray detectors are essential for medical radiography,industrial inspection and security screening.Lowering the radiation dose allows reduced health risks and increased frequency and fidelity of...Sensitive and reliable X-ray detectors are essential for medical radiography,industrial inspection and security screening.Lowering the radiation dose allows reduced health risks and increased frequency and fidelity of diagnostic technologies for earlier detection of disease and its recurrence.Three-dimensional(3 D)organic-inorganic hybrid lead halide perovskites are promising for direct X-ray detection-they show improved sensitivity compared to conventional X-ray detectors.However,their high and unstable dark current,caused by ion migration and high dark carrier concentration in the 3 D hybrid perovskites,limits their performance and long-term operation stability.Here we report ultrasensitive,stable X-ray detectors made using zero-dimensional(0 D)methylammonium bismuth iodide perovskite(MA3Bi2I9)single crystals.The 0 D crystal structure leads to a high activation energy(Ea)for ion migration(0.46 e V)and is also accompanied by a low dark carrier concentration(~10^6 cm^-3).The X-ray detectors exhibit sensitivity of 10,620μC Gy-1 air cm-2,a limit of detection(Lo D)of 0.62 nG yairs-1,and stable operation even under high applied biases;no deterioration in detection performance was observed following sensing of an integrated X-ray irradiation dose of^23,800 m Gyair,equivalent to>200,000 times the dose required for a single commercial X-ray chest radiograph.Regulating the ion migration channels and decreasing the dark carrier concentration in perovskites provide routes for stable and ultrasensitive X-ray detectors.展开更多
The latest studies with radiological imaging techniques indicate that X-ray images provide valuable details on the Coronavirus disease 2019(COVID-19).The usage of sophisticated artificial intelligence technology(AI)an...The latest studies with radiological imaging techniques indicate that X-ray images provide valuable details on the Coronavirus disease 2019(COVID-19).The usage of sophisticated artificial intelligence technology(AI)and the radiological images can help in diagnosing the disease reliably and addressing the problem of the shortage of trained doctors in remote villages.In this research,the automated diagnosis of Coronavirus disease was performed using a dataset of X-ray images of patients with severe bacterial pneumonia,reported COVID-19 disease,and normal cases.The goal of the study is to analyze the achievements for medical image recognition of state-of-the-art neural networking architectures.Transfer Learning technique has been implemented in this work.Transfer learning is an ambitious task,but it results in impressive outcomes for identifying distinct patterns in tiny datasets of medical images.The findings indicate that deep learning with X-ray imagery could retrieve important biomarkers relevant for COVID-19 disease detection.Since all diagnostic measures show failure levels that pose questions,the scientific profession should determine the probability of integration of X-rays with the clinical treatment,utilizing the results.The proposed model achieved 96.73%accuracy outperforming the ResNet50 and traditional Resnet18 models.Based on our findings,the proposed system can help the specialist doctors in making verdicts for COVID-19 detection.展开更多
The coronavirus disease 2019(COVID-19)pandemic has had a devastating impact on the health and welfare of the global population.A key measure to combat COVID-19 has been the effective screening of infected patients.A v...The coronavirus disease 2019(COVID-19)pandemic has had a devastating impact on the health and welfare of the global population.A key measure to combat COVID-19 has been the effective screening of infected patients.A vital screening process is the chest radiograph.Initial studies have shown irregularities in the chest radiographs of COVID-19 patients.The use of the chest X-ray(CXR),a leading diagnostic technique,has been encouraged and driven by several ongoing projects to combat this disease because of its historical effectiveness in providing clinical insights on lung diseases.This study introduces a dilated bi-branched convoluted neural network(CNN)architecture,VGG-COVIDNet,to detect COVID-19 cases from CXR images.The front end of the VGG-COVIDNet consists of the first 10 layers of VGG-16,where the convolutional layers in these layers are reduced to two to minimize latency during the training phase.The last two branches of the proposed architecture consist of dilated convolutional layers to reduce the model’s computational complexity while retaining the feature maps’spatial information.The simulation results show that the proposed architecture is superior to all the state-of-the-art architecture in accuracy and sensitivity.The proposed architecture’s accuracy and sensitivity are 96.5%and 96%,respectively,for each infection type.展开更多
Ten soil samples from Jabal Al Qur, Wadi Baba, and Wadi Sieh in Sinai, Egypt, were analyzed by XRD spectroscopy. The XRD spectroscopy results indicate that the major, minor and trace constituents varied from one sampl...Ten soil samples from Jabal Al Qur, Wadi Baba, and Wadi Sieh in Sinai, Egypt, were analyzed by XRD spectroscopy. The XRD spectroscopy results indicate that the major, minor and trace constituents varied from one sample to another. Samples were also analyzed by HPGe gamma spectrometer to determine the activity concentration of U-238, Th-232 series and K-40. The concentrations for 238U ranged from 57.03 to 4220.41 Bq/kg with an average 1110.75 Bq/kg, for 232Th, ranged from 13.55 to130.46 Bq/kg with an average 71.85 Bq/Kg. The concentrations for 40K were in the range from 12.18 to 948.93 Bq/kg with an average value 457.09 Bq/kg. The average activity concentration values of 226Ra, 232Th, and 40K, in all the collected samples were higher than the world average. The radium equivalent (Req), absorbed dose rate (DR), the effective dose rate (Deff), and hazard indices resulted due to the natural radionuclides in soil are also calculated. The Results show that the study area is not safe for human and environments.展开更多
Igneous and sedimentary rocks contain an amount of natural radioactivity (NORM). U-238, Th-232 and their decay products, and K-40 are important sources of gamma-radiation. Knowledge of the radionuclide content of rock...Igneous and sedimentary rocks contain an amount of natural radioactivity (NORM). U-238, Th-232 and their decay products, and K-40 are important sources of gamma-radiation. Knowledge of the radionuclide content of rocks is necessary to estimate the exposure of the population to the radiation. Many types of rocks are used in building and industries, thus the radiation detection is important, it provides a baseline map of levels of the radioactivity in the study region. The purpose of this study is to evaluate the activity concentrations of the natural radionuclides (U-238 (Ra-226), Th-232 and K-40) and the fallout nuclide (Cs-137) (if found) in thirty samples of igneous and sedimentary rocks of Al-Atawilah (Al-Baha). The samples were collected and prepared during 2018/2019, and analyzed with a good experimental instrument (High energy resolution γ-ray spectroscopy with HPGe detector), also these rock samples were analyzed with X-ray fluorescence to subdivided these rocks based on the major oxides proportions contained of each sample. The mean activity concentrations of naturally radionuclides were found in the igneous rock samples varied depending on the type of the igneous rock. For sedimentary rock samples, the activity concentrations were found high for quartz sandstone sample, which may be due to its high proportion of SiO<sub>2</sub> and K<sub>2</sub>O. The estimated mean values of absorbed dose rate are within the permissible limit value. The findings indicate high dose level values in granite (rhyolite) and most of diorite (andesite) igneous rock samples while gabbro (basalt) igneous rock samples (except for one sample) record low levels of dose rate. All sedimentary rock samples have low dose rate (except for the quartz sand-stone sample).展开更多
文摘Objective To observe the value of artificial intelligence(AI)models based on non-contrast chest CT for measuring bone mineral density(BMD).Methods Totally 380 subjects who underwent both non-contrast chest CT and quantitative CT(QCT)BMD examination were retrospectively enrolled and divided into training set(n=304)and test set(n=76)at a ratio of 8∶2.The mean BMD of L1—L3 vertebrae were measured based on QCT.Spongy bones of T5—T10 vertebrae were segmented as ROI,radiomics(Rad)features were extracted,and machine learning(ML),Rad and deep learning(DL)models were constructed for classification of osteoporosis(OP)and evaluating BMD,respectively.Receiver operating characteristic curves were drawn,and area under the curves(AUC)were calculated to evaluate the efficacy of each model for classification of OP.Bland-Altman analysis and Pearson correlation analysis were performed to explore the consistency and correlation of each model with QCT for measuring BMD.Results Among ML and Rad models,ML Bagging-OP and Rad Bagging-OP had the best performances for classification of OP.In test set,AUC of ML Bagging-OP,Rad Bagging-OP and DL OP for classification of OP was 0.943,0.944 and 0.947,respectively,with no significant difference(all P>0.05).BMD obtained with all the above models had good consistency with those measured with QCT(most of the differences were within the range of Ax-G±1.96 s),which were highly positively correlated(r=0.910—0.974,all P<0.001).Conclusion AI models based on non-contrast chest CT had high efficacy for classification of OP,and good consistency of BMD measurements were found between AI models and QCT.
文摘Objective To observe the value of self-supervised deep learning artificial intelligence(AI)noise reduction technology based on the nearest adjacent layer applicated in ultra-low dose CT(ULDCT)for urinary calculi.Methods Eighty-eight urinary calculi patients were prospectively enrolled.Low dose CT(LDCT)and ULDCT scanning were performed,and the effective dose(ED)of each scanning protocol were calculated.The patients were then randomly divided into training set(n=75)and test set(n=13),and a self-supervised deep learning AI noise reduction system based on the nearest adjacent layer constructed with ULDCT images in training set was used for reducing noise of ULDCT images in test set.In test set,the quality of ULDCT images before and after AI noise reduction were compared with LDCT images,i.e.Blind/Referenceless Image Spatial Quality Evaluator(BRISQUE)scores,image noise(SD ROI)and signal-to-noise ratio(SNR).Results The tube current,the volume CT dose index and the dose length product of abdominal ULDCT scanning protocol were all lower compared with those of LDCT scanning protocol(all P<0.05),with a decrease of ED for approximately 82.66%.For 13 patients with urinary calculi in test set,BRISQUE score showed that the quality level of ULDCT images before AI noise reduction reached 54.42%level but raised to 95.76%level of LDCT images after AI noise reduction.Both ULDCT images after AI noise reduction and LDCT images had lower SD ROI and higher SNR than ULDCT images before AI noise reduction(all adjusted P<0.05),whereas no significant difference was found between the former two(both adjusted P>0.05).Conclusion Self-supervised learning AI noise reduction technology based on the nearest adjacent layer could effectively reduce noise and improve image quality of urinary calculi ULDCT images,being conducive for clinical application of ULDCT.
文摘A chest radiology scan can significantly aid the early diagnosis and management of COVID-19 since the virus attacks the lungs.Chest X-ray(CXR)gained much interest after the COVID-19 outbreak thanks to its rapid imaging time,widespread availability,low cost,and portability.In radiological investigations,computer-aided diagnostic tools are implemented to reduce intra-and inter-observer variability.Using lately industrialized Artificial Intelligence(AI)algorithms and radiological techniques to diagnose and classify disease is advantageous.The current study develops an automatic identification and classification model for CXR pictures using Gaussian Fil-tering based Optimized Synergic Deep Learning using Remora Optimization Algorithm(GF-OSDL-ROA).This method is inclusive of preprocessing and classification based on optimization.The data is preprocessed using Gaussian filtering(GF)to remove any extraneous noise from the image’s edges.Then,the OSDL model is applied to classify the CXRs under different severity levels based on CXR data.The learning rate of OSDL is optimized with the help of ROA for COVID-19 diagnosis showing the novelty of the work.OSDL model,applied in this study,was validated using the COVID-19 dataset.The experiments were conducted upon the proposed OSDL model,which achieved a classification accuracy of 99.83%,while the current Convolutional Neural Network achieved less classification accuracy,i.e.,98.14%.
基金supported by the National Natural Science Foundation of China(Grant nos.21773218,61974063)the Sichuan Province(Grant no.2018JY0206)the China Academy of Engineering Physics(Grant no.YZJJLX2018007)。
文摘Sensitive and reliable X-ray detectors are essential for medical radiography,industrial inspection and security screening.Lowering the radiation dose allows reduced health risks and increased frequency and fidelity of diagnostic technologies for earlier detection of disease and its recurrence.Three-dimensional(3 D)organic-inorganic hybrid lead halide perovskites are promising for direct X-ray detection-they show improved sensitivity compared to conventional X-ray detectors.However,their high and unstable dark current,caused by ion migration and high dark carrier concentration in the 3 D hybrid perovskites,limits their performance and long-term operation stability.Here we report ultrasensitive,stable X-ray detectors made using zero-dimensional(0 D)methylammonium bismuth iodide perovskite(MA3Bi2I9)single crystals.The 0 D crystal structure leads to a high activation energy(Ea)for ion migration(0.46 e V)and is also accompanied by a low dark carrier concentration(~10^6 cm^-3).The X-ray detectors exhibit sensitivity of 10,620μC Gy-1 air cm-2,a limit of detection(Lo D)of 0.62 nG yairs-1,and stable operation even under high applied biases;no deterioration in detection performance was observed following sensing of an integrated X-ray irradiation dose of^23,800 m Gyair,equivalent to>200,000 times the dose required for a single commercial X-ray chest radiograph.Regulating the ion migration channels and decreasing the dark carrier concentration in perovskites provide routes for stable and ultrasensitive X-ray detectors.
文摘The latest studies with radiological imaging techniques indicate that X-ray images provide valuable details on the Coronavirus disease 2019(COVID-19).The usage of sophisticated artificial intelligence technology(AI)and the radiological images can help in diagnosing the disease reliably and addressing the problem of the shortage of trained doctors in remote villages.In this research,the automated diagnosis of Coronavirus disease was performed using a dataset of X-ray images of patients with severe bacterial pneumonia,reported COVID-19 disease,and normal cases.The goal of the study is to analyze the achievements for medical image recognition of state-of-the-art neural networking architectures.Transfer Learning technique has been implemented in this work.Transfer learning is an ambitious task,but it results in impressive outcomes for identifying distinct patterns in tiny datasets of medical images.The findings indicate that deep learning with X-ray imagery could retrieve important biomarkers relevant for COVID-19 disease detection.Since all diagnostic measures show failure levels that pose questions,the scientific profession should determine the probability of integration of X-rays with the clinical treatment,utilizing the results.The proposed model achieved 96.73%accuracy outperforming the ResNet50 and traditional Resnet18 models.Based on our findings,the proposed system can help the specialist doctors in making verdicts for COVID-19 detection.
基金funded by Institutional Fund projects(Grant No.IFPHI-255-611-2020).
文摘The coronavirus disease 2019(COVID-19)pandemic has had a devastating impact on the health and welfare of the global population.A key measure to combat COVID-19 has been the effective screening of infected patients.A vital screening process is the chest radiograph.Initial studies have shown irregularities in the chest radiographs of COVID-19 patients.The use of the chest X-ray(CXR),a leading diagnostic technique,has been encouraged and driven by several ongoing projects to combat this disease because of its historical effectiveness in providing clinical insights on lung diseases.This study introduces a dilated bi-branched convoluted neural network(CNN)architecture,VGG-COVIDNet,to detect COVID-19 cases from CXR images.The front end of the VGG-COVIDNet consists of the first 10 layers of VGG-16,where the convolutional layers in these layers are reduced to two to minimize latency during the training phase.The last two branches of the proposed architecture consist of dilated convolutional layers to reduce the model’s computational complexity while retaining the feature maps’spatial information.The simulation results show that the proposed architecture is superior to all the state-of-the-art architecture in accuracy and sensitivity.The proposed architecture’s accuracy and sensitivity are 96.5%and 96%,respectively,for each infection type.
文摘Ten soil samples from Jabal Al Qur, Wadi Baba, and Wadi Sieh in Sinai, Egypt, were analyzed by XRD spectroscopy. The XRD spectroscopy results indicate that the major, minor and trace constituents varied from one sample to another. Samples were also analyzed by HPGe gamma spectrometer to determine the activity concentration of U-238, Th-232 series and K-40. The concentrations for 238U ranged from 57.03 to 4220.41 Bq/kg with an average 1110.75 Bq/kg, for 232Th, ranged from 13.55 to130.46 Bq/kg with an average 71.85 Bq/Kg. The concentrations for 40K were in the range from 12.18 to 948.93 Bq/kg with an average value 457.09 Bq/kg. The average activity concentration values of 226Ra, 232Th, and 40K, in all the collected samples were higher than the world average. The radium equivalent (Req), absorbed dose rate (DR), the effective dose rate (Deff), and hazard indices resulted due to the natural radionuclides in soil are also calculated. The Results show that the study area is not safe for human and environments.
文摘Igneous and sedimentary rocks contain an amount of natural radioactivity (NORM). U-238, Th-232 and their decay products, and K-40 are important sources of gamma-radiation. Knowledge of the radionuclide content of rocks is necessary to estimate the exposure of the population to the radiation. Many types of rocks are used in building and industries, thus the radiation detection is important, it provides a baseline map of levels of the radioactivity in the study region. The purpose of this study is to evaluate the activity concentrations of the natural radionuclides (U-238 (Ra-226), Th-232 and K-40) and the fallout nuclide (Cs-137) (if found) in thirty samples of igneous and sedimentary rocks of Al-Atawilah (Al-Baha). The samples were collected and prepared during 2018/2019, and analyzed with a good experimental instrument (High energy resolution γ-ray spectroscopy with HPGe detector), also these rock samples were analyzed with X-ray fluorescence to subdivided these rocks based on the major oxides proportions contained of each sample. The mean activity concentrations of naturally radionuclides were found in the igneous rock samples varied depending on the type of the igneous rock. For sedimentary rock samples, the activity concentrations were found high for quartz sandstone sample, which may be due to its high proportion of SiO<sub>2</sub> and K<sub>2</sub>O. The estimated mean values of absorbed dose rate are within the permissible limit value. The findings indicate high dose level values in granite (rhyolite) and most of diorite (andesite) igneous rock samples while gabbro (basalt) igneous rock samples (except for one sample) record low levels of dose rate. All sedimentary rock samples have low dose rate (except for the quartz sand-stone sample).