Because of their economy and applicability,high-power thyristor devices are widely used in the power supply systems for large fusion devices.When high-dose neutrons produced by deuterium–tritium(D–T)fusion reactions...Because of their economy and applicability,high-power thyristor devices are widely used in the power supply systems for large fusion devices.When high-dose neutrons produced by deuterium–tritium(D–T)fusion reactions are irradiated on a thyristor device for a long time,the electrical characteristics of the device change,which may eventually cause irreversible damage.In this study,with the thyristor switch of the commutation circuit in the quench protection system(QPS)of a fusion device as the study object,the relationship between the internal physical structure and external electrical parameters of the irradiated thyristor is established.Subsequently,a series of targeted thyristor physical simulations and neutron irradiation experiments are conducted to verify the accuracy of the theoretical analysis.In addition,the effect of irradiated thyristor electrical characteristic changes on the entire QPS is studied by accurate simulation,providing valuable guidelines for the maintenance and renovation of the QPS.展开更多
Space objects such as spacecraft or missiles may be exposed to intense X-rays in outer space,leading to severe damage.The reinforcement of these objects to reduce the damage caused by X-ray irradiation is a significan...Space objects such as spacecraft or missiles may be exposed to intense X-rays in outer space,leading to severe damage.The reinforcement of these objects to reduce the damage caused by X-ray irradiation is a significant concern.The blow-off impulse(BOI)is a crucial physical quantity for investigating material damage induced by X-ray irradiation.However,the accurate calculation of BOI is challenging,particularly for large deformations of materials with complex configurations.In this study,we develop a novel two-dimensional particle-in-cell code,Xablation2D,to calculate BOIs under far-field X-ray irradiation.This significantly reduces the dependence of the numerical simulation on the grid shape.The reliability of this code is verified by simulation results from open-source codes,and the calculated BOIs are consistent with the experimental and analytical results.展开更多
Silicon neutron transmutation doping remains one of the most viable nuclear applications for research reactors.Providing this kind of product involves an irradiation method capable of fulfilling the quality requiremen...Silicon neutron transmutation doping remains one of the most viable nuclear applications for research reactors.Providing this kind of product involves an irradiation method capable of fulfilling the quality requirements of doping and alleviating the challenges related to the design and safety of the irradiation device.In this paper,we propose an irradiation device prototype for neutron transmutation doping of silicon ingots with diameters of 2 to 3 in.based on the Es-Salam research reactor.The thermal hydraulic analysis of the proposed irradiation device was performed to determine the optimum conditions for cooling.The effect of the mechanical vibrations induced by the circulation of coolant in the device was quantified via experimental measurements under different flow rates.The results show that the maximum temperature reached by the silicon ingots is below the temperature limit,effectively validating the design of the irradiation device.Other investigations are prospected to further optimize the design and the irradiation conditions.The irradiation of silicon ingots with a large diameter will be considered.展开更多
In a deuterium operation on the Large Helical Device, the measurement and control equipment placed in the toms hall must survive under an environment of radiation, To study the effects of gamma-ray irradiation on the ...In a deuterium operation on the Large Helical Device, the measurement and control equipment placed in the toms hall must survive under an environment of radiation, To study the effects of gamma-ray irradiation on the equipment, an irradiation experiment is performed at the Cobalt-60 irradiation facility of Nagoya University. Transient and permanent effects on a personal computer, media converters, programmable logic controllers, isolation amplifiers, a web camera, optical flow meters, and water sealing gaskets are experimentally surveyed. Transient noise appears on the web camera. Offset of the signal increases with an increase of the integrated dose on the programmable logic controller. The DeviceNet module on the programmable logic controller is broken at the integrated dose of 72 Gy, which is the expected range of the integrated dose of the toms hall. The other equipment can survive under the gamma-ray field in the toms hall.展开更多
In this review,the application of light ion irradiation is discussed for tailoring novel functional materials and for improving the performance in SiC or Si based electrical power devices.The deep traps and electronic...In this review,the application of light ion irradiation is discussed for tailoring novel functional materials and for improving the performance in SiC or Si based electrical power devices.The deep traps and electronic disorder produced by light ion irradiation can modify the electrical,magnetic,and optical properties of films(e.g.,dilute ferromagnetic semiconductors and topological materials).Additionally,benefiting from the high reproducibility,precise manipulation of functional depth and density of defects,as well as the flexible patternability,the helium or proton ion irradiation has been successfully employed in improving the dynamic performance of SiC and Si based PiN diode power devices by reducing their majority carrier lifetime,although the static performance is sacrificed due to deep level traps.Such a trade-off has been regarded as the key point to compromise the static and dynamic performances of power devices.As a result,herein the light ion irradiation is highlighted in both exploring new physics and optimizing the performance in functional materials and electrical devices.展开更多
Objective To observe the effects of signal factors of corticosterone (CS), cAMP, cGMP, Ca^2+ and protein kinase C (PKC) on lymphocyte apoptosis in mouse thymus induced by X-rays of 4 Gy in vitro. Methods The DNA ...Objective To observe the effects of signal factors of corticosterone (CS), cAMP, cGMP, Ca^2+ and protein kinase C (PKC) on lymphocyte apoptosis in mouse thymus induced by X-rays of 4 Gy in vitro. Methods The DNA lyric rate for thymocytes was measured by fluomspectrophotometry. Results The DNA lyric rate for thymocytes 4-8 hours after irradiation with 2-8 Gy was significantly higher than that in the control (P〈0.01). As compared with the control, the DNA lyric rate for thymocytes treated with 0.01 μnol/L CS (P〈0.01), 50 ng/mL cAMP (P〈0.01), 0.05-0.4 μg/mL ionomycin (Iono, P〈0.05 or P〈0.01) or 0.05-0.4 ng/mL phorbol myristate acetate (PMA, P〈0.05 or P〈0.01), respectively, was significantly increased, while the rate for thymocytes treated with 50 ng/mL cGMP was not significantly increased. The DNA lyric rate for thymocytes treated with 0.01 μmol/L CS (P〈0.01), 50 ng/mL cAMP (P〈0.01), 0.2 and 0.4 μg/mL Iono (P〈0.05), and 0.2 and 0.4 ng/mL PMA (P〈0.05) plus 4-Gy irradiation, respectively, was significantly higher than that treated with single 4-Gy irradiation, while the rate for thymocytes treated with 50 ng/mL cGMP plus 4-Gy irradiation was not increased. When both 0.4 I.tg/mL Iono and 0.4 ng/mL PMA acted on the thymocytes, the DNA lyric rate for thymocytes was significantly higher than that in the control (P〈0.01), the DNA lytic rate for thymocytes treated with both 0.4 μg/mL Iono and 0.4 ng/mL PMA plus 4-Gy irradiation was significantly higher than that treated with single 4-Gy irradiation (P〈0.05), but was Iono plus 4-Gy irradiation or 0.4 ng/mL PMA plus 4-Gy irradiation. can promote thymocyte apoptosis induced by larger dose X-rays. not significantly higher than that treated with 0.4 μg/mL Conclusion CS, cAMP, Ca^2+, and PKC signal factors can promote thymocyte apoptosis induced by larger dose X-rays.展开更多
Commercially available AlGaN/GaN high-electron-mobility transistors(HEMTs)are beginning to enter the public scene froma range of suppliers.Based on previous studies,commercial GaN-based electronics are expected to be ...Commercially available AlGaN/GaN high-electron-mobility transistors(HEMTs)are beginning to enter the public scene froma range of suppliers.Based on previous studies,commercial GaN-based electronics are expected to be tolerant to different types of irradiation in space.To test this assumption,we compared the characteristic electrical curves obtained at different X-ray irradiation doses for GaN HEMT devices manufactured by Infineon and Transphorm.The p-GaN-based device was found to be more robust with a stable threshold voltage,whereas the threshold voltage of the device with ametal-insulator-semiconductor gatewas found to shift first in the negative and then the positive direction.This dynamic phenomenon is caused by the releasing and trapping effects of radiation-induced charges in the dielectric layer and at the interface of irradiated devices.As such,the p-GaNgate-based GaN HEMT provides a promising solution for use as an electric source in space.展开更多
The multi-radiation of X-rays was investigated with special attention to their energy spectrum in a Mather-type plasma focus device (operated with argon gas). The analysis is based on the effect of anomalous resista...The multi-radiation of X-rays was investigated with special attention to their energy spectrum in a Mather-type plasma focus device (operated with argon gas). The analysis is based on the effect of anomalous resistances. To study the energy spectrum, a four-channel diode X-ray spectrometer was used along with a special set of filters. The filters were suitable for detection of medium range X-rays as well as hard X-rays with energy exceeding 30 keV. The results indicate that the anomalous resistivity effect during the post pinch phase may cause multi-radiation of X-rays with a total duration of 300 ± 50 ns. The significant contribution of Cu-Kα was due to the medium range X-rays, nonetheless, hard X-rays with energies greater than 15 keV also participate in the process. The total emitted X-ray energy in the forms of Cu-K and Cu-K/3 was around 0.14 ± 0.02 (J/Sr) and 0.04 ±0.01 (J/Sr), respectively. The total energy of the emitted hard X-ray (〉 15 keV) was around 0.12± 0.02 (J/Sr).展开更多
Based on the two-dimensional model, this paper compares the hydrodynamics of slab x-ray laser plasma produced by different nonuniform line focused irradiations. It finds that the average intensity and the duration of ...Based on the two-dimensional model, this paper compares the hydrodynamics of slab x-ray laser plasma produced by different nonuniform line focused irradiations. It finds that the average intensity and the duration of laser pulse and the overall shape of the intensity distribution in the focal line have different influences on the plasma. Calculations show that the evolution of temperature variation is more sensitive to the pulse duration and the electron density variation is more sensitive to the pulse intensity. Pulses with duration of 200 ps to 500 ps and with intensity of 0.2 TW/cm2 to 1.0 TW/cm2 are proved acceptable in slab x-ray lasers.展开更多
A method to measure the detailed performance of polycapillary x-ray optics by a pinhole and charge coupled device(CCD)detector was proposed in this study.The pinhole was located between the x-ray source and the polyca...A method to measure the detailed performance of polycapillary x-ray optics by a pinhole and charge coupled device(CCD)detector was proposed in this study.The pinhole was located between the x-ray source and the polycapillary x-ray optics to determine the illuminating region of the incident x-ray beam on the input side of the optics.The CCD detector placed downstream of the polycapillary x-ray optics ensured that the incident x-ray beam controlled by the pinhole irradiated a specific region of the input surface of the optics.The intensity of the output beam of the polycapillary x-ray optics was obtained from the far-field image of the output beam of the optics captured by CCD detector.As an application example,the focal spot size,gain in power density,transmission efficiency,and beam divergence of different parts of a polycapillary focusing x-ray lenses(PFXRL)were measured by a pinhole and CCD detector.Three pinholes with diameters of 500,1000,and 2000μm were used to adjust the diameter of the incident x-ray beam illuminating the PFXRL from 500μm to the entire surface of the input side of the PFXRL.The focal spot size of the PFXRL,gain in power density,transmission efficiency,and beam divergence ranged from 27.1μm to 34.6μm,400 to 3460,26.70%to 5.38%,and 16.8 mrad to 84.86 mrad,respectively.展开更多
The hematological effects of space radiation contribute to the compromised immune defense in astronauts observed in the space environment as well as upon landing[1]. The complications associated with the hematopoietic...The hematological effects of space radiation contribute to the compromised immune defense in astronauts observed in the space environment as well as upon landing[1]. The complications associated with the hematopoietic syndrome include infection and internal hemorrhage. The decrease in peripheral blood cell counts after radiation serves not only as a marker for the severity of the exposure, but also as a marker for treatment and prognosis[2]. In the present research, we investigated the effects of whole-body heavy-ion (80 MeV/u carbon-ion) radiation and conventional X-ray (6 MV) radiation on peripheral blood cell counts in mice model. Time effects were determined to compare the effects of the different types of radiation.展开更多
This paper mainly reports the permanent impact of displacement damage induced by heavy-ion strikes on the deepsubmicron MOSFETs. Upon the heavy ion track through the device, it can lead to displacement damage, includi...This paper mainly reports the permanent impact of displacement damage induced by heavy-ion strikes on the deepsubmicron MOSFETs. Upon the heavy ion track through the device, it can lead to displacement damage, including the vacancies and the interstitials. As the featured size of device scales down, the damage can change the dopant distribution in the channel and source/drain regions through the generation of radiation-induced defects and thus have significant impacts on their electrical characteristics. The measured results show that the radiation-induced damage can cause DC characteristics degradations including the threshold voltage, subthreshold swing, saturation drain current, transconductanee, etc. The radiation-induced displacement damage may become the dominant issue while it was the secondary concern for the traditional devices after the heavy ion irradiation. The samples are also irradiated by Co- 60 gamma ray for comparison with the heavy ion irradiation results. Corresponding explanations and analysis are discussed.展开更多
AIM: To evaluate αB-crystallin malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione peroxidase (GPx) changes in X-ray irradiated rat lens. METHODS: Eight-week-old Sprague-Dawley male rats received X-ray ...AIM: To evaluate αB-crystallin malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione peroxidase (GPx) changes in X-ray irradiated rat lens. METHODS: Eight-week-old Sprague-Dawley male rats received X-ray irradiation to the head with rest of the body protected. The exposure dose ranged from 2 to 25 Grays (Gy). The cataract status were examined by slit lamp and rated with 'four-grade systems' post-irradiation. The lens MDA level, and the activities of SOD and GPx were measured in a short-term experiment post-irradiation, and αB-crystallin protein levels were quantified. RESULTS: The lenses of normal control and the X-ray irradiated groups with the dose up to 10 Gy remained transparent throughout the experiment. The lens first appeared tiny scatters, and even lamellar opacities in the posterior capsule 45 days post-irradiation with the dose of 15 Gy, and progressed slowly to the advance stage of cataract; while, for the higher dose (25 Gy), the opacity of lens appeared much earlier, and progressed more rapidly to mature stage of cataract within 1 month. At the end of the observation (90 days post-irradiation), almost all lenses became complete opacity with the higher dose (25 Gy). The degree of lens opacity was rated accordingly. The lens MDA level was increased, and SOD and GPx activities were decreased with a dose-dependent manner post-irradiation. The αB-crystallin protein level was decreased dose-dependently at the end point of observation. CONCLUSION: Oxidative events and αB-crystallin may play important roles in the pathogenesis of cataract in X-ray irradiated rat lens.展开更多
The total dose effect of ^(60)Co γ-rays on 0.8μm H-gate partially depleted-silicon-on-insulator NMOS devices was investigated at different irradiation doses. The results show that the shift in saturation current at ...The total dose effect of ^(60)Co γ-rays on 0.8μm H-gate partially depleted-silicon-on-insulator NMOS devices was investigated at different irradiation doses. The results show that the shift in saturation current at high dose rate is greater than that at low dose rate, due to increase in interface-state density with decreasing dose rate; the scattering effect of interface state on electrons in the channel causes degradation in carrier mobility; and the body current and transconductance of the back gate enhance low-doserate sensitivity when the irradiation is under OFF-bias. A double transconductance peak is observed at 3 kGy(Si)under high dose rates.展开更多
Between October 1985 and June 1992 Postoperative kelolds of 125 Patients were treated with superficial X-ray (100-140 Kv) and electron beam (6 and 9 MeV ), in an attempt to prevent their recurrence, 100 patients with ...Between October 1985 and June 1992 Postoperative kelolds of 125 Patients were treated with superficial X-ray (100-140 Kv) and electron beam (6 and 9 MeV ), in an attempt to prevent their recurrence, 100 patients with 129 sites received a dose of 1200-4000 cGy at 200-300 cGy per fraction within one to four weeks and at intervals of one to three weeks between excision and irradiation. Rate of success In the prevention of kelold was only 28. 6% (37/ 129). However, 25 patients with 25 sites received a total dose of 1500 cGy at 500 cGy per fraction starting within one week after excision and at Intervals of 96 hours. The success rate was 84% (21/25).展开更多
The problems of agriculture in Senegal result in a low yield per hectare and poor seed quality contributing strongly to the decline in productivity. Mutagenesis by X- or Y-ray irradiation makes it possible to obtain g...The problems of agriculture in Senegal result in a low yield per hectare and poor seed quality contributing strongly to the decline in productivity. Mutagenesis by X- or Y-ray irradiation makes it possible to obtain genetic mutants necessary to improve production. It is in this context that we undertook this study to evaluate the effects induced on the cultivation of peanut seeds irradiated by X-rays at low doses applied in radiotherapy. X-ray irradiation of four (2, 3, 4, 5) lots of peanuts are performed with respectively 0.5, 1.5, 2 and 4 Gray using the cobalt 60 therapy device (Alcyon II). The seeding of the seeds and then the following-up of the crops during 35 days allowed us to study the parameters of germination, growth and yield. The results obtained after monitoring revealed that the irradiation did not have any significant impact on germination and would appear to temporarily inhibit the growth rate compared to the control batch. However, the decrease in weight of the harvested seeds can be explained by the absence of fertilizer during the cultivation.展开更多
A high-efficiency synthesis method for a latent pigment of red pigment diketo-pyrrolo-pyrrole (Pig. Red 272:272DPP), which is important as a functional organic pigment, was investigated, and the investigation results ...A high-efficiency synthesis method for a latent pigment of red pigment diketo-pyrrolo-pyrrole (Pig. Red 272:272DPP), which is important as a functional organic pigment, was investigated, and the investigation results revealed that irradiation of microwaves (MWs) for several seconds to 272 DPP in NMP (N-methyl-2-pyrrolidone) solvent yielded DPP latent pigment (272DPP-BOC) at a high yield of 86.2%. Two kinds of latent-pigment crystals, namely, red and yellow, were obtained by recrystallization, and it was found that the fluorescence-emission properties of the two kinds differ significantly. Single-crystal X-ray structural analysis showed that the difference in the fluorescence-emission properties of the two types is derived from the difference in their crystal structures.展开更多
TRISO (Tri-structural iso-tropic)-coated particle fuel is being developed to support the development of a VHTR (very high temperature reactor) in Korea. From August 2013, the first irradiation testing of coated pa...TRISO (Tri-structural iso-tropic)-coated particle fuel is being developed to support the development of a VHTR (very high temperature reactor) in Korea. From August 2013, the first irradiation testing of coated particle fuel was begun to demonstrate and qualify TRISO fuel for use in the VHTR in HANARO (high-flux advanced neutron application reactor) at KAERI (Korea Atomic Energy Research Institute). This experiment is currently undergoing under an atmosphere of a mixed inert gas without on-line temperature monitoring and control combined with on-line fission product monitoring of the sweep gas. The irradiation device contains two test rods, one contains nine fuel compacts and the other five compacts and eight graphite specimens. Each compact has 263 coated particles. After a peak bum-up of about 4% and a peak fast neutron fluence of about 1.7 × 1021 n/cm2, PIE (post irradiation examination) will be carried out at KAERI's irradiated material examination facility. This paper describes the characteristics of coated particle fuels, and the design of the test rod and irradiation device for the coated particle fuels, and discusses the technical results of irradiation testing at HANARO.展开更多
Experimental study is performed to design and develop a cylindrical micro-pump driven by expansion and contraction of the heat deformation material, whose variation is caused with the aid of heating and cooling proper...Experimental study is performed to design and develop a cylindrical micro-pump driven by expansion and contraction of the heat deformation material, whose variation is caused with the aid of heating and cooling properties of Peltier devices. The pump consists of the diffuser valve unit, the heat deformation material unit, the nozzle valve unit, the Peltier devices and the cover. The input current of the Peltier devices is controlled by the bipolar power supply so that the Peltier devices are heated and cooled periodically. The working fluid flow in the micro-pump is caused by the periodical thermal deformation of material which is caused by the periodical heating and cooling of the Peltier devices. In order to measure the fluid flow in the micro-pump, micro air bubbles are employed as a tracer. The corresponding movement is recorded by X-ray apparatus and its velocity is measured by PIV (particle image velocimetry). It is found that, the micro-pump developed here can make the working fluid flow. The corresponding fluid flow in the micro pump is confirmed by the numerical method.展开更多
基金supported by the Fundamental Research Funds for the Central University(No.JZ2023HGTA0182)Comprehensive Research Facility for Fusion Technology Program of China(No.2018-000052-73-01-001228)。
文摘Because of their economy and applicability,high-power thyristor devices are widely used in the power supply systems for large fusion devices.When high-dose neutrons produced by deuterium–tritium(D–T)fusion reactions are irradiated on a thyristor device for a long time,the electrical characteristics of the device change,which may eventually cause irreversible damage.In this study,with the thyristor switch of the commutation circuit in the quench protection system(QPS)of a fusion device as the study object,the relationship between the internal physical structure and external electrical parameters of the irradiated thyristor is established.Subsequently,a series of targeted thyristor physical simulations and neutron irradiation experiments are conducted to verify the accuracy of the theoretical analysis.In addition,the effect of irradiated thyristor electrical characteristic changes on the entire QPS is studied by accurate simulation,providing valuable guidelines for the maintenance and renovation of the QPS.
基金supported by the National Science Foundation of China(No.12347103)the Fundamental Research Funds for the Central Universities(No.226-2022-00216)。
文摘Space objects such as spacecraft or missiles may be exposed to intense X-rays in outer space,leading to severe damage.The reinforcement of these objects to reduce the damage caused by X-ray irradiation is a significant concern.The blow-off impulse(BOI)is a crucial physical quantity for investigating material damage induced by X-ray irradiation.However,the accurate calculation of BOI is challenging,particularly for large deformations of materials with complex configurations.In this study,we develop a novel two-dimensional particle-in-cell code,Xablation2D,to calculate BOIs under far-field X-ray irradiation.This significantly reduces the dependence of the numerical simulation on the grid shape.The reliability of this code is verified by simulation results from open-source codes,and the calculated BOIs are consistent with the experimental and analytical results.
基金supported by the Nuclear Research Centre of Birine of Algerian Atomic Energy Commission.
文摘Silicon neutron transmutation doping remains one of the most viable nuclear applications for research reactors.Providing this kind of product involves an irradiation method capable of fulfilling the quality requirements of doping and alleviating the challenges related to the design and safety of the irradiation device.In this paper,we propose an irradiation device prototype for neutron transmutation doping of silicon ingots with diameters of 2 to 3 in.based on the Es-Salam research reactor.The thermal hydraulic analysis of the proposed irradiation device was performed to determine the optimum conditions for cooling.The effect of the mechanical vibrations induced by the circulation of coolant in the device was quantified via experimental measurements under different flow rates.The results show that the maximum temperature reached by the silicon ingots is below the temperature limit,effectively validating the design of the irradiation device.Other investigations are prospected to further optimize the design and the irradiation conditions.The irradiation of silicon ingots with a large diameter will be considered.
基金supported partly by the LHD project budget(NIFS15ULHH003 and NIFS15ULGG801)
文摘In a deuterium operation on the Large Helical Device, the measurement and control equipment placed in the toms hall must survive under an environment of radiation, To study the effects of gamma-ray irradiation on the equipment, an irradiation experiment is performed at the Cobalt-60 irradiation facility of Nagoya University. Transient and permanent effects on a personal computer, media converters, programmable logic controllers, isolation amplifiers, a web camera, optical flow meters, and water sealing gaskets are experimentally surveyed. Transient noise appears on the web camera. Offset of the signal increases with an increase of the integrated dose on the programmable logic controller. The DeviceNet module on the programmable logic controller is broken at the integrated dose of 72 Gy, which is the expected range of the integrated dose of the toms hall. The other equipment can survive under the gamma-ray field in the toms hall.
基金This work was supported by Key-Area Research and Development Program of Guangdong Province(No.2019B 010132001)This work was also partially funded by Guangdong Basic and Applied Basic Research Foundation(2020A1515110891).
文摘In this review,the application of light ion irradiation is discussed for tailoring novel functional materials and for improving the performance in SiC or Si based electrical power devices.The deep traps and electronic disorder produced by light ion irradiation can modify the electrical,magnetic,and optical properties of films(e.g.,dilute ferromagnetic semiconductors and topological materials).Additionally,benefiting from the high reproducibility,precise manipulation of functional depth and density of defects,as well as the flexible patternability,the helium or proton ion irradiation has been successfully employed in improving the dynamic performance of SiC and Si based PiN diode power devices by reducing their majority carrier lifetime,although the static performance is sacrificed due to deep level traps.Such a trade-off has been regarded as the key point to compromise the static and dynamic performances of power devices.As a result,herein the light ion irradiation is highlighted in both exploring new physics and optimizing the performance in functional materials and electrical devices.
基金This study was supported by a grant from the National Natural Science Foundation of China (No. 391702750)
文摘Objective To observe the effects of signal factors of corticosterone (CS), cAMP, cGMP, Ca^2+ and protein kinase C (PKC) on lymphocyte apoptosis in mouse thymus induced by X-rays of 4 Gy in vitro. Methods The DNA lyric rate for thymocytes was measured by fluomspectrophotometry. Results The DNA lyric rate for thymocytes 4-8 hours after irradiation with 2-8 Gy was significantly higher than that in the control (P〈0.01). As compared with the control, the DNA lyric rate for thymocytes treated with 0.01 μnol/L CS (P〈0.01), 50 ng/mL cAMP (P〈0.01), 0.05-0.4 μg/mL ionomycin (Iono, P〈0.05 or P〈0.01) or 0.05-0.4 ng/mL phorbol myristate acetate (PMA, P〈0.05 or P〈0.01), respectively, was significantly increased, while the rate for thymocytes treated with 50 ng/mL cGMP was not significantly increased. The DNA lyric rate for thymocytes treated with 0.01 μmol/L CS (P〈0.01), 50 ng/mL cAMP (P〈0.01), 0.2 and 0.4 μg/mL Iono (P〈0.05), and 0.2 and 0.4 ng/mL PMA (P〈0.05) plus 4-Gy irradiation, respectively, was significantly higher than that treated with single 4-Gy irradiation, while the rate for thymocytes treated with 50 ng/mL cGMP plus 4-Gy irradiation was not increased. When both 0.4 I.tg/mL Iono and 0.4 ng/mL PMA acted on the thymocytes, the DNA lyric rate for thymocytes was significantly higher than that in the control (P〈0.01), the DNA lytic rate for thymocytes treated with both 0.4 μg/mL Iono and 0.4 ng/mL PMA plus 4-Gy irradiation was significantly higher than that treated with single 4-Gy irradiation (P〈0.05), but was Iono plus 4-Gy irradiation or 0.4 ng/mL PMA plus 4-Gy irradiation. can promote thymocyte apoptosis induced by larger dose X-rays. not significantly higher than that treated with 0.4 μg/mL Conclusion CS, cAMP, Ca^2+, and PKC signal factors can promote thymocyte apoptosis induced by larger dose X-rays.
基金Thisworkwas supported by the National Key R&D Programof China(No.2017YFB0402800,2017YFB0402802).
文摘Commercially available AlGaN/GaN high-electron-mobility transistors(HEMTs)are beginning to enter the public scene froma range of suppliers.Based on previous studies,commercial GaN-based electronics are expected to be tolerant to different types of irradiation in space.To test this assumption,we compared the characteristic electrical curves obtained at different X-ray irradiation doses for GaN HEMT devices manufactured by Infineon and Transphorm.The p-GaN-based device was found to be more robust with a stable threshold voltage,whereas the threshold voltage of the device with ametal-insulator-semiconductor gatewas found to shift first in the negative and then the positive direction.This dynamic phenomenon is caused by the releasing and trapping effects of radiation-induced charges in the dielectric layer and at the interface of irradiated devices.As such,the p-GaNgate-based GaN HEMT provides a promising solution for use as an electric source in space.
文摘The multi-radiation of X-rays was investigated with special attention to their energy spectrum in a Mather-type plasma focus device (operated with argon gas). The analysis is based on the effect of anomalous resistances. To study the energy spectrum, a four-channel diode X-ray spectrometer was used along with a special set of filters. The filters were suitable for detection of medium range X-rays as well as hard X-rays with energy exceeding 30 keV. The results indicate that the anomalous resistivity effect during the post pinch phase may cause multi-radiation of X-rays with a total duration of 300 ± 50 ns. The significant contribution of Cu-Kα was due to the medium range X-rays, nonetheless, hard X-rays with energies greater than 15 keV also participate in the process. The total emitted X-ray energy in the forms of Cu-K and Cu-K/3 was around 0.14 ± 0.02 (J/Sr) and 0.04 ±0.01 (J/Sr), respectively. The total energy of the emitted hard X-ray (〉 15 keV) was around 0.12± 0.02 (J/Sr).
基金suported by the National Natural Science Foundation of China (Grant No. 10874242)the National Basic Research Program of China (973 Program) (Grant No. 2007CB815105)Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20070290008)
文摘Based on the two-dimensional model, this paper compares the hydrodynamics of slab x-ray laser plasma produced by different nonuniform line focused irradiations. It finds that the average intensity and the duration of laser pulse and the overall shape of the intensity distribution in the focal line have different influences on the plasma. Calculations show that the evolution of temperature variation is more sensitive to the pulse duration and the electron density variation is more sensitive to the pulse intensity. Pulses with duration of 200 ps to 500 ps and with intensity of 0.2 TW/cm2 to 1.0 TW/cm2 are proved acceptable in slab x-ray lasers.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11675019,12105020,and 12075031)the Bud Project of Beijing Academy of Science and Technology(Grant No.BGS202106)the National Key Research and Development Program of China(Grant No.2021YFF0701202)
文摘A method to measure the detailed performance of polycapillary x-ray optics by a pinhole and charge coupled device(CCD)detector was proposed in this study.The pinhole was located between the x-ray source and the polycapillary x-ray optics to determine the illuminating region of the incident x-ray beam on the input side of the optics.The CCD detector placed downstream of the polycapillary x-ray optics ensured that the incident x-ray beam controlled by the pinhole irradiated a specific region of the input surface of the optics.The intensity of the output beam of the polycapillary x-ray optics was obtained from the far-field image of the output beam of the optics captured by CCD detector.As an application example,the focal spot size,gain in power density,transmission efficiency,and beam divergence of different parts of a polycapillary focusing x-ray lenses(PFXRL)were measured by a pinhole and CCD detector.Three pinholes with diameters of 500,1000,and 2000μm were used to adjust the diameter of the incident x-ray beam illuminating the PFXRL from 500μm to the entire surface of the input side of the PFXRL.The focal spot size of the PFXRL,gain in power density,transmission efficiency,and beam divergence ranged from 27.1μm to 34.6μm,400 to 3460,26.70%to 5.38%,and 16.8 mrad to 84.86 mrad,respectively.
文摘The hematological effects of space radiation contribute to the compromised immune defense in astronauts observed in the space environment as well as upon landing[1]. The complications associated with the hematopoietic syndrome include infection and internal hemorrhage. The decrease in peripheral blood cell counts after radiation serves not only as a marker for the severity of the exposure, but also as a marker for treatment and prognosis[2]. In the present research, we investigated the effects of whole-body heavy-ion (80 MeV/u carbon-ion) radiation and conventional X-ray (6 MV) radiation on peripheral blood cell counts in mice model. Time effects were determined to compare the effects of the different types of radiation.
基金Project supported by the National Natural Science Foundation of China (Grants No. 60625403,60836004,60925015 and 90207004)the Major State Basic Research Development Program of China (973 Program) (Grant No. 2006CB302701)
文摘This paper mainly reports the permanent impact of displacement damage induced by heavy-ion strikes on the deepsubmicron MOSFETs. Upon the heavy ion track through the device, it can lead to displacement damage, including the vacancies and the interstitials. As the featured size of device scales down, the damage can change the dopant distribution in the channel and source/drain regions through the generation of radiation-induced defects and thus have significant impacts on their electrical characteristics. The measured results show that the radiation-induced damage can cause DC characteristics degradations including the threshold voltage, subthreshold swing, saturation drain current, transconductanee, etc. The radiation-induced displacement damage may become the dominant issue while it was the secondary concern for the traditional devices after the heavy ion irradiation. The samples are also irradiated by Co- 60 gamma ray for comparison with the heavy ion irradiation results. Corresponding explanations and analysis are discussed.
基金Scientific Research Foundation for Returned Scholars, the Second Hospital Affiliated to Soochow University (No.SDFEY-2007-10)National Natural Science Foundation of China (No.81000383)+2 种基金Research Fund for the Doctoral Program of Higher Education of China (No.20100072120051)Program of Tongji University (No.1500219024 No.2010QH04 and No. 2010YF02)
文摘AIM: To evaluate αB-crystallin malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione peroxidase (GPx) changes in X-ray irradiated rat lens. METHODS: Eight-week-old Sprague-Dawley male rats received X-ray irradiation to the head with rest of the body protected. The exposure dose ranged from 2 to 25 Grays (Gy). The cataract status were examined by slit lamp and rated with 'four-grade systems' post-irradiation. The lens MDA level, and the activities of SOD and GPx were measured in a short-term experiment post-irradiation, and αB-crystallin protein levels were quantified. RESULTS: The lenses of normal control and the X-ray irradiated groups with the dose up to 10 Gy remained transparent throughout the experiment. The lens first appeared tiny scatters, and even lamellar opacities in the posterior capsule 45 days post-irradiation with the dose of 15 Gy, and progressed slowly to the advance stage of cataract; while, for the higher dose (25 Gy), the opacity of lens appeared much earlier, and progressed more rapidly to mature stage of cataract within 1 month. At the end of the observation (90 days post-irradiation), almost all lenses became complete opacity with the higher dose (25 Gy). The degree of lens opacity was rated accordingly. The lens MDA level was increased, and SOD and GPx activities were decreased with a dose-dependent manner post-irradiation. The αB-crystallin protein level was decreased dose-dependently at the end point of observation. CONCLUSION: Oxidative events and αB-crystallin may play important roles in the pathogenesis of cataract in X-ray irradiated rat lens.
基金supported by the National Natural Science Foundation of China(No.61376099)the Foundation for Fundamental Research of China(No.JSZL2016110B003)the Major Fundamental Research Program of Shaanxi(No.2017ZDJC-26)
文摘The total dose effect of ^(60)Co γ-rays on 0.8μm H-gate partially depleted-silicon-on-insulator NMOS devices was investigated at different irradiation doses. The results show that the shift in saturation current at high dose rate is greater than that at low dose rate, due to increase in interface-state density with decreasing dose rate; the scattering effect of interface state on electrons in the channel causes degradation in carrier mobility; and the body current and transconductance of the back gate enhance low-doserate sensitivity when the irradiation is under OFF-bias. A double transconductance peak is observed at 3 kGy(Si)under high dose rates.
文摘Between October 1985 and June 1992 Postoperative kelolds of 125 Patients were treated with superficial X-ray (100-140 Kv) and electron beam (6 and 9 MeV ), in an attempt to prevent their recurrence, 100 patients with 129 sites received a dose of 1200-4000 cGy at 200-300 cGy per fraction within one to four weeks and at intervals of one to three weeks between excision and irradiation. Rate of success In the prevention of kelold was only 28. 6% (37/ 129). However, 25 patients with 25 sites received a total dose of 1500 cGy at 500 cGy per fraction starting within one week after excision and at Intervals of 96 hours. The success rate was 84% (21/25).
文摘The problems of agriculture in Senegal result in a low yield per hectare and poor seed quality contributing strongly to the decline in productivity. Mutagenesis by X- or Y-ray irradiation makes it possible to obtain genetic mutants necessary to improve production. It is in this context that we undertook this study to evaluate the effects induced on the cultivation of peanut seeds irradiated by X-rays at low doses applied in radiotherapy. X-ray irradiation of four (2, 3, 4, 5) lots of peanuts are performed with respectively 0.5, 1.5, 2 and 4 Gray using the cobalt 60 therapy device (Alcyon II). The seeding of the seeds and then the following-up of the crops during 35 days allowed us to study the parameters of germination, growth and yield. The results obtained after monitoring revealed that the irradiation did not have any significant impact on germination and would appear to temporarily inhibit the growth rate compared to the control batch. However, the decrease in weight of the harvested seeds can be explained by the absence of fertilizer during the cultivation.
文摘A high-efficiency synthesis method for a latent pigment of red pigment diketo-pyrrolo-pyrrole (Pig. Red 272:272DPP), which is important as a functional organic pigment, was investigated, and the investigation results revealed that irradiation of microwaves (MWs) for several seconds to 272 DPP in NMP (N-methyl-2-pyrrolidone) solvent yielded DPP latent pigment (272DPP-BOC) at a high yield of 86.2%. Two kinds of latent-pigment crystals, namely, red and yellow, were obtained by recrystallization, and it was found that the fluorescence-emission properties of the two kinds differ significantly. Single-crystal X-ray structural analysis showed that the difference in the fluorescence-emission properties of the two types is derived from the difference in their crystal structures.
文摘TRISO (Tri-structural iso-tropic)-coated particle fuel is being developed to support the development of a VHTR (very high temperature reactor) in Korea. From August 2013, the first irradiation testing of coated particle fuel was begun to demonstrate and qualify TRISO fuel for use in the VHTR in HANARO (high-flux advanced neutron application reactor) at KAERI (Korea Atomic Energy Research Institute). This experiment is currently undergoing under an atmosphere of a mixed inert gas without on-line temperature monitoring and control combined with on-line fission product monitoring of the sweep gas. The irradiation device contains two test rods, one contains nine fuel compacts and the other five compacts and eight graphite specimens. Each compact has 263 coated particles. After a peak bum-up of about 4% and a peak fast neutron fluence of about 1.7 × 1021 n/cm2, PIE (post irradiation examination) will be carried out at KAERI's irradiated material examination facility. This paper describes the characteristics of coated particle fuels, and the design of the test rod and irradiation device for the coated particle fuels, and discusses the technical results of irradiation testing at HANARO.
文摘Experimental study is performed to design and develop a cylindrical micro-pump driven by expansion and contraction of the heat deformation material, whose variation is caused with the aid of heating and cooling properties of Peltier devices. The pump consists of the diffuser valve unit, the heat deformation material unit, the nozzle valve unit, the Peltier devices and the cover. The input current of the Peltier devices is controlled by the bipolar power supply so that the Peltier devices are heated and cooled periodically. The working fluid flow in the micro-pump is caused by the periodical thermal deformation of material which is caused by the periodical heating and cooling of the Peltier devices. In order to measure the fluid flow in the micro-pump, micro air bubbles are employed as a tracer. The corresponding movement is recorded by X-ray apparatus and its velocity is measured by PIV (particle image velocimetry). It is found that, the micro-pump developed here can make the working fluid flow. The corresponding fluid flow in the micro pump is confirmed by the numerical method.