X-ray-induced acoustic computed tomography(XACT)is a hybrid imaging modality for detecting X-ray absorption distribution via ultrasound emission.It facilitates imaging from a single projection X-ray illumination,thus ...X-ray-induced acoustic computed tomography(XACT)is a hybrid imaging modality for detecting X-ray absorption distribution via ultrasound emission.It facilitates imaging from a single projection X-ray illumination,thus reducing the radiation exposure and improving imaging speed.Nonuniform detector response caused by the interference between multichannel data acquisition for ring array transducers and amplifier systems yields ring artifacts in the reconstructed XACT images,which compromises the image quality.We propose model-based algorithms for ring artifacts corrected XACT imaging and demonstrate their effcacy on numerical and experimental measurements.The corrected reconstructions indicate significantly reduced ring artifacts as compared to their conventional counterparts.展开更多
This study examined ionizing radiation-induced tumor necrosis factor （ligand） superfamily, member 4 （TNFSF4） mRNA expression changes in human peripheral blood cells and their distribution in a normal population. T...This study examined ionizing radiation-induced tumor necrosis factor （ligand） superfamily, member 4 （TNFSF4） mRNA expression changes in human peripheral blood cells and their distribution in a normal population. The results showed that expression level of TNFSF4 mRNA exhibited a dose- dependent response after different irradiation doses, but that was independent of incubation time post-irradiation. Moreover, it was not affected by age and gender in 51 healthy donors. Our studies indicate that TNFSF4 can be considered as a candidate gene to develop a new biodosimeter.展开更多
基金supported by the National Cancer Institute of the National Institutes of Health under Award No.(R37CA240806).
文摘X-ray-induced acoustic computed tomography(XACT)is a hybrid imaging modality for detecting X-ray absorption distribution via ultrasound emission.It facilitates imaging from a single projection X-ray illumination,thus reducing the radiation exposure and improving imaging speed.Nonuniform detector response caused by the interference between multichannel data acquisition for ring array transducers and amplifier systems yields ring artifacts in the reconstructed XACT images,which compromises the image quality.We propose model-based algorithms for ring artifacts corrected XACT imaging and demonstrate their effcacy on numerical and experimental measurements.The corrected reconstructions indicate significantly reduced ring artifacts as compared to their conventional counterparts.
基金supported by the National Key Clinical Special Department of China(Grant No.2011-17)the Medical Science and Technology Foundation of Henan Province(Grant No.201003146 and No.201303202)
文摘This study examined ionizing radiation-induced tumor necrosis factor （ligand） superfamily, member 4 （TNFSF4） mRNA expression changes in human peripheral blood cells and their distribution in a normal population. The results showed that expression level of TNFSF4 mRNA exhibited a dose- dependent response after different irradiation doses, but that was independent of incubation time post-irradiation. Moreover, it was not affected by age and gender in 51 healthy donors. Our studies indicate that TNFSF4 can be considered as a candidate gene to develop a new biodosimeter.
