X-ray-induced acoustic computed tomography(XACT)is a hybrid imaging modality for detecting X-ray absorption distribution via ultrasound emission.It facilitates imaging from a single projection X-ray illumination,thus ...X-ray-induced acoustic computed tomography(XACT)is a hybrid imaging modality for detecting X-ray absorption distribution via ultrasound emission.It facilitates imaging from a single projection X-ray illumination,thus reducing the radiation exposure and improving imaging speed.Nonuniform detector response caused by the interference between multichannel data acquisition for ring array transducers and amplifier systems yields ring artifacts in the reconstructed XACT images,which compromises the image quality.We propose model-based algorithms for ring artifacts corrected XACT imaging and demonstrate their effcacy on numerical and experimental measurements.The corrected reconstructions indicate significantly reduced ring artifacts as compared to their conventional counterparts.展开更多
Two novel ultrasound imaging techniques with imaging contrast mechanisms are in the works:X-ray-induced acoustic computed tomography(XACT),and nanoscale photoacoustic tomogra-phy(nPAT).XACT has incredible potential in...Two novel ultrasound imaging techniques with imaging contrast mechanisms are in the works:X-ray-induced acoustic computed tomography(XACT),and nanoscale photoacoustic tomogra-phy(nPAT).XACT has incredible potential in:(1)biomedical imaging,through which a 3D image can be generated using only a single X-ray projection,and(2)radiation dosimetry.nPATas a new alternative of super-resolution microscopy can break through the optical difraction limitand is capable of exploring sub-celular structures without reliance on fuorescence labeling.We expect these new imaging techniques to find widespread applications in both pre-clinical andclinical biomedical research.展开更多
基金supported by the National Cancer Institute of the National Institutes of Health under Award No.(R37CA240806).
文摘X-ray-induced acoustic computed tomography(XACT)is a hybrid imaging modality for detecting X-ray absorption distribution via ultrasound emission.It facilitates imaging from a single projection X-ray illumination,thus reducing the radiation exposure and improving imaging speed.Nonuniform detector response caused by the interference between multichannel data acquisition for ring array transducers and amplifier systems yields ring artifacts in the reconstructed XACT images,which compromises the image quality.We propose model-based algorithms for ring artifacts corrected XACT imaging and demonstrate their effcacy on numerical and experimental measurements.The corrected reconstructions indicate significantly reduced ring artifacts as compared to their conventional counterparts.
文摘Two novel ultrasound imaging techniques with imaging contrast mechanisms are in the works:X-ray-induced acoustic computed tomography(XACT),and nanoscale photoacoustic tomogra-phy(nPAT).XACT has incredible potential in:(1)biomedical imaging,through which a 3D image can be generated using only a single X-ray projection,and(2)radiation dosimetry.nPATas a new alternative of super-resolution microscopy can break through the optical difraction limitand is capable of exploring sub-celular structures without reliance on fuorescence labeling.We expect these new imaging techniques to find widespread applications in both pre-clinical andclinical biomedical research.
