Huaihe River Basin(HRB) is located in China’s north-south climatic transition zone,which is very sensitive to global climate change.Based on the daily maximum temperature,minimum temperature,and precipitation data of...Huaihe River Basin(HRB) is located in China’s north-south climatic transition zone,which is very sensitive to global climate change.Based on the daily maximum temperature,minimum temperature,and precipitation data of 40 meteorological stations and nine monthly large-scale ocean-atmospheric circulation indices data during 1959–2019,we present an assessment of the spatial and temporal variations of extreme temperature and precipitation events in the HRB using nine extreme climate indices,and analyze the teleconnection relationship between extreme climate indices and large-scale ocean-atmospheric circulation indices.The results show that warm extreme indices show a significant(P < 0.05) increasing trend,while cold extreme indices(except for cold spell duration) and diurnal temperature range(DTR) show a significant decreasing trend.Furthermore,all extreme temperature indices show significant mutations during 1959-2019.Spatially,a stronger warming trend occurs in eastern HRB than western HRB,while maximum 5-d precipitation(Rx5day) and rainstorm days(R25) show an increasing trend in the southern,central,and northwestern regions of HRB.Arctic oscillation(AO),Atlantic multidecadal oscillation(AMO),and East Atlantic/Western Russia(EA/WR) have a stronger correlation with extreme climate indices compared to other circulation indices.AO and AMO(EA/WR) exhibit a significant(P < 0.05) negative(positive)correlation with frost days and diurnal temperature range.Extreme warm events are strongly correlated with the variability of AMO and EA/WR in most parts of HRB,while extreme cold events are closely related to the variability of AO and AMO in eastern HRB.In contrast,AMO,AO,and EA/WR show limited impacts on extreme precipitation events in most parts of HRB.展开更多
The Walker circulation is one of the major components of the large-scale tropical atmospheric circulation and variations in its strength are critical to equatorial Pacific Ocean circulation. It has been argued in the ...The Walker circulation is one of the major components of the large-scale tropical atmospheric circulation and variations in its strength are critical to equatorial Pacific Ocean circulation. It has been argued in the literature that during the 20th century the Walker circulation weakened, and that this weakening was attributable to anthropogenic climate change. By using updated observations, we show that there has been a rapid interdecadal enhancement of the Walker circulation since the late 1990s. Associated with this enhancement is enhanced precipitation in the tropical western Pacific, anomalous westerlies in the upper troposphere, descent in the central and eastern tropical Pacific, and anomalous surface easterlies in the western and central tropical Pacific. The characteristics of associated oceanic changes are a strengthened thermocline slope and an enhanced zonal SST gradient across the tropical Pacific. Many characteristics of these changes are similar to those associated with the mid-1970s climate shift with an opposite sign. We also show that the interdecadal variability of the Walker circulation in the tropical Pacific is inversely correlated to the interdecadal variability of the zonal circulation in the tropical Atlantic. An enhancement of the Walker circulation in the tropical Pacific is associated with a weakening zonal circulation in the tropical Atlantic and vise versa, implying an inter-Atlantic-Pacific connection of the zonal overturning circulation variation. Whether these recent changes will be sustained is not yet clear, but our research highlights the importance of understanding the interdecadal variability, as well as the long-term trends, that influence tropical circulation.展开更多
Atmospheric or climate phenomena are usually a combination of elementary events whose scales range from the very small (microscopic) to the infinitely large (synoptic). This means that build reasoning from ground- or ...Atmospheric or climate phenomena are usually a combination of elementary events whose scales range from the very small (microscopic) to the infinitely large (synoptic). This means that build reasoning from ground- or space-based observations only, regardless of the physics of elementary processes, inevitably leads to erroneous results. Given the fact that plots of Troposphere Tricellular Circulation are only based on weather mean conditions measured near the ground (i.e.: pressure and winds fields observed at the surface of the earth), we want to improve these representations of the general circulation of the atmosphere, by using both Clausius-Clapeyron Relation and Carnot Principle derived respectively in 1832 and 1824. Indeed, Clausius-Clapeyron relation shows precisely that, unlike the dry water vapor that can be assimilated to the ideal gas at many circumstances, the saturated water vapor has, in an air parcel at the same time cold (temperature below 0.0098°C) and rich in moisture (vapor pressure above 6.11 mb), thermoelastic properties diametrically opposed to those of ideal gas (including dry water vapor). Vertical profiles of temperature and water vapor in the atmosphere provided by ground- or space-based observations lead to the location of a troposphere region in which the ideal gas assumption should be banned: hence appropriate and unique plot of earth’s atmosphere tricellular circulation.展开更多
A real case study for the transformation of Tropical Storm (TS) Haima (2004) into an extratropical cyclone (EC) is carried out numerically since,after landfall,Haima (2004) (as an EC) brought severe weather ...A real case study for the transformation of Tropical Storm (TS) Haima (2004) into an extratropical cyclone (EC) is carried out numerically since,after landfall,Haima (2004) (as an EC) brought severe weather to a large area (from the south to the north) in China during 13-16 September 2004.With the linear diagnostic model (derived in a previous study) for the tangentially-averaged radial-vertical circulation within vortices moving on the spherical Earth,Haima's (2004) life cycle is reconstructed noticeably well.Therefore,the major contributor could be identified confidently for Haima's (2004) extratropical transition based on the diagnostic model outputs.The quantitative comparison shows that up to a 90% contribution to the innerregion updraft and a 55% contribution to the upper-layer outflow come from latent heating during Haima's (2004) TS stage.Up to a 90% contribution to the inner-region updraft and nearly a 100% contribution to the upper-layer outflow come from the upper-layer eddy angular momentum advection (EAMA) during Haima's (2004) EC stage.Representing the asymmetric structure of the storm,the predominantly positive contribution of the upper-layer EAMA to Haima's (2004) transformation is closely associated with the Sshaped westerlies in the upper layer with two jets.One jet in the cyclonic-curvature area carries cyclonic angular momentum into the storm,and the other jet in the anticyclonic-curvature area carries anticyclonic angular momentum out of the storm.Consequently,the newly-increased cyclonic tangential wind is deflected by the Coriolis force to the right to form the upper-layer outflow accompanied by the central-area rising motion,leading to Haima's (2004) extratropical transition after its landfall.展开更多
The aim of this study was to systematically review the evidence for the effectiveness of Buerger’s exercise on the peripheral circulation or diabetic foot ulceration. A systematic search and 18 electronic databases w...The aim of this study was to systematically review the evidence for the effectiveness of Buerger’s exercise on the peripheral circulation or diabetic foot ulceration. A systematic search and 18 electronic databases were conducted. The intervention was predominantly focused on Buerger’s exercise as an outcome. Due to high heterogeneity, data were synthesized in a narrative format rather than by statistical methods. Nine studies that covered 592 participants were selected in the analysis, of which 8 of the 9 found an effect of Buerger’s exercise on peripheral circulation. The positive effects were indicative of improving blood flow, walking ability, reducing necrosis, reducing venous embolism, pain, swelling, cyanosis and the bed-rest times. However, the study design and quality appraisal were limited to Jadad score 2 and the sample size was small. Findings provide some evidence of the beneficial effects of Buerger’s exercises. It was seen as a low cost and low risk physical activity that most diabetic patients could undertake at home. This review highlighted a need for further investigation of standardized procedures of Buerger’s exercises. More high quality studies on the prevention of diabetic foot are required regarding Buerger’s exercises.展开更多
While China’s internal market potential is getting more and more tempting, Minister Zhang Haoruo of Internal Trade says in the years to come the retail, wholesale and material sectors will be freed up for foreign inv...While China’s internal market potential is getting more and more tempting, Minister Zhang Haoruo of Internal Trade says in the years to come the retail, wholesale and material sectors will be freed up for foreign investment. Foreign businessmen will be welcome to compete in China. The Minister disclose "t that 11 cities had been approved to experiment展开更多
AIM:Microcirculatory disturbances are important early pathophysiological events in various organs during acute pancreatitis.The aim of the study was to evaluate changes in microperfusion of the pancreas,liver,kidney,s...AIM:Microcirculatory disturbances are important early pathophysiological events in various organs during acute pancreatitis.The aim of the study was to evaluate changes in microperfusion of the pancreas,liver,kidney,stomach, colon,skeletal muscle,and to investigate the influence of heparin on the organ microcirculation in caerulein-induced experimental acute pancreatitis. METHODS:Acute pancreatitis was induced by 4 intraperitoneal injections of caerulein(Cn)(15 μg/kg).The organ microcirculation was measured by laser Doppler flowmetry.Serum interleukin 6 and hematocrit levels were analysed. RESULTS:Acute pancreatitis resulted in a significant drop of microperfusion in all examined organs.Heparin administration(2×2.5 mg/kg)improved the microcirculation in pancreas(36.9±4% vs 75.9±10%),liver(56.6±6% vs 75.2±16%),kidney (45.1±6% vs 79.3±5%),stomach (65.2±8% vs 78.1±19%),colon(69.8±6% vs 102.5±19%), and skeletal muscle (59.2±6% vs 77.9±13%).Heparin treatment lowered IL-6(359.0±66 U/mL vs 288.5±58 U/mL) and hematocrit level(53±4% vs 46±3%). CONCLUSION:Heparin administration has a positive influence on organ microcirculatory disturbances accompanying experimental Cn-induced acute pancreatitis.展开更多
α-Synuclein is a protein that mainly exists in the presynaptic terminals.Abnormal folding and accumulation of α-synuclein are found in several neurodegenerative diseases,including Parkinson’s disease.Aggregated and...α-Synuclein is a protein that mainly exists in the presynaptic terminals.Abnormal folding and accumulation of α-synuclein are found in several neurodegenerative diseases,including Parkinson’s disease.Aggregated and highly phospho rylated a-synuclein constitutes the main component of Lewy bodies in the brain,the pathological hallmark of Parkinson s disease.For decades,much attention has been focused on the accumulation of α-synuclein in the brain parenchyma rather than considering Parkinson s disease as a systemic disease.Recent evidence demonstrates that,at least in some patients,the initial α-synuclein pathology originates in the peripheral organs and spreads to the brain.Injection of α-synuclein preformed fibrils into the gastrointestinal tra ct trigge rs the gutto-brain propagation of α-synuclein pathology.However,whether α-synuclein pathology can occur spontaneously in peripheral organs independent of exogenous α-synuclein preformed fibrils or pathological α-synuclein leakage from the central nervous system remains under investigation.In this review,we aimed to summarize the role of peripheral α-synuclein pathology in the pathogenesis of Parkinson’s disease.We also discuss the pathways by which α-synuclein pathology spreads from the body to the brain.展开更多
Symmetric circulant matrices (or shortly symmetric circulants) are a very special class of matrices sometimes arising in problems of discrete periodic convolutions with symmetric kernel. First, we collect major proper...Symmetric circulant matrices (or shortly symmetric circulants) are a very special class of matrices sometimes arising in problems of discrete periodic convolutions with symmetric kernel. First, we collect major properties of symmetric circulants scattered through the literature. Second, we report two new applications of these matrices to isotropic Markov chain models and electrical impedance tomography on a homogeneous disk with equidistant electrodes. A new special function is introduced for computation of the Ohm’s matrix. The latter application is illustrated with estimation of the resistivity of gelatin using an electrical impedance tomography setup.展开更多
The Xinjiang Production andConstruction Corps (XPCC) was foundedin October 1954. Since 1990, its plan hasbeen listed directly under the state councilof PRC.After 50 years of arduouspioneering and development, the XPCC...The Xinjiang Production andConstruction Corps (XPCC) was foundedin October 1954. Since 1990, its plan hasbeen listed directly under the state councilof PRC.After 50 years of arduouspioneering and development, the XPCChas now developed to be a specialorganization with a solid economicstrength and enterprise group superiority,which is based on the large-scale andmodernized agriculture, and guided展开更多
基金Under the auspices of National Natural Science Foundation of China(No.52279016,51909106,51879108,42002247,41471160)Natural Science Foundation of Guangdong Province,China(No.2020A1515011038,2020A1515111054)+1 种基金Special Fund for Science and Technology Development in 2016 of Department of Science and Technology of Guangdong Province,China(No.2016A020223007)the Project of Jinan Science and Technology Bureau(No.2021GXRC070)。
文摘Huaihe River Basin(HRB) is located in China’s north-south climatic transition zone,which is very sensitive to global climate change.Based on the daily maximum temperature,minimum temperature,and precipitation data of 40 meteorological stations and nine monthly large-scale ocean-atmospheric circulation indices data during 1959–2019,we present an assessment of the spatial and temporal variations of extreme temperature and precipitation events in the HRB using nine extreme climate indices,and analyze the teleconnection relationship between extreme climate indices and large-scale ocean-atmospheric circulation indices.The results show that warm extreme indices show a significant(P < 0.05) increasing trend,while cold extreme indices(except for cold spell duration) and diurnal temperature range(DTR) show a significant decreasing trend.Furthermore,all extreme temperature indices show significant mutations during 1959-2019.Spatially,a stronger warming trend occurs in eastern HRB than western HRB,while maximum 5-d precipitation(Rx5day) and rainstorm days(R25) show an increasing trend in the southern,central,and northwestern regions of HRB.Arctic oscillation(AO),Atlantic multidecadal oscillation(AMO),and East Atlantic/Western Russia(EA/WR) have a stronger correlation with extreme climate indices compared to other circulation indices.AO and AMO(EA/WR) exhibit a significant(P < 0.05) negative(positive)correlation with frost days and diurnal temperature range.Extreme warm events are strongly correlated with the variability of AMO and EA/WR in most parts of HRB,while extreme cold events are closely related to the variability of AO and AMO in eastern HRB.In contrast,AMO,AO,and EA/WR show limited impacts on extreme precipitation events in most parts of HRB.
基金supported by the National Basic Research Program of China (Grant No. 2010CB950400)
文摘The Walker circulation is one of the major components of the large-scale tropical atmospheric circulation and variations in its strength are critical to equatorial Pacific Ocean circulation. It has been argued in the literature that during the 20th century the Walker circulation weakened, and that this weakening was attributable to anthropogenic climate change. By using updated observations, we show that there has been a rapid interdecadal enhancement of the Walker circulation since the late 1990s. Associated with this enhancement is enhanced precipitation in the tropical western Pacific, anomalous westerlies in the upper troposphere, descent in the central and eastern tropical Pacific, and anomalous surface easterlies in the western and central tropical Pacific. The characteristics of associated oceanic changes are a strengthened thermocline slope and an enhanced zonal SST gradient across the tropical Pacific. Many characteristics of these changes are similar to those associated with the mid-1970s climate shift with an opposite sign. We also show that the interdecadal variability of the Walker circulation in the tropical Pacific is inversely correlated to the interdecadal variability of the zonal circulation in the tropical Atlantic. An enhancement of the Walker circulation in the tropical Pacific is associated with a weakening zonal circulation in the tropical Atlantic and vise versa, implying an inter-Atlantic-Pacific connection of the zonal overturning circulation variation. Whether these recent changes will be sustained is not yet clear, but our research highlights the importance of understanding the interdecadal variability, as well as the long-term trends, that influence tropical circulation.
文摘Atmospheric or climate phenomena are usually a combination of elementary events whose scales range from the very small (microscopic) to the infinitely large (synoptic). This means that build reasoning from ground- or space-based observations only, regardless of the physics of elementary processes, inevitably leads to erroneous results. Given the fact that plots of Troposphere Tricellular Circulation are only based on weather mean conditions measured near the ground (i.e.: pressure and winds fields observed at the surface of the earth), we want to improve these representations of the general circulation of the atmosphere, by using both Clausius-Clapeyron Relation and Carnot Principle derived respectively in 1832 and 1824. Indeed, Clausius-Clapeyron relation shows precisely that, unlike the dry water vapor that can be assimilated to the ideal gas at many circumstances, the saturated water vapor has, in an air parcel at the same time cold (temperature below 0.0098°C) and rich in moisture (vapor pressure above 6.11 mb), thermoelastic properties diametrically opposed to those of ideal gas (including dry water vapor). Vertical profiles of temperature and water vapor in the atmosphere provided by ground- or space-based observations lead to the location of a troposphere region in which the ideal gas assumption should be banned: hence appropriate and unique plot of earth’s atmosphere tricellular circulation.
基金sponsored by the National Key Basic Research Project of China(2009CB421404)Chinese NSF key project (Grant No.40730951)the National Natural Sciences Foundation of China (Grant No. 40575021)
文摘A real case study for the transformation of Tropical Storm (TS) Haima (2004) into an extratropical cyclone (EC) is carried out numerically since,after landfall,Haima (2004) (as an EC) brought severe weather to a large area (from the south to the north) in China during 13-16 September 2004.With the linear diagnostic model (derived in a previous study) for the tangentially-averaged radial-vertical circulation within vortices moving on the spherical Earth,Haima's (2004) life cycle is reconstructed noticeably well.Therefore,the major contributor could be identified confidently for Haima's (2004) extratropical transition based on the diagnostic model outputs.The quantitative comparison shows that up to a 90% contribution to the innerregion updraft and a 55% contribution to the upper-layer outflow come from latent heating during Haima's (2004) TS stage.Up to a 90% contribution to the inner-region updraft and nearly a 100% contribution to the upper-layer outflow come from the upper-layer eddy angular momentum advection (EAMA) during Haima's (2004) EC stage.Representing the asymmetric structure of the storm,the predominantly positive contribution of the upper-layer EAMA to Haima's (2004) transformation is closely associated with the Sshaped westerlies in the upper layer with two jets.One jet in the cyclonic-curvature area carries cyclonic angular momentum into the storm,and the other jet in the anticyclonic-curvature area carries anticyclonic angular momentum out of the storm.Consequently,the newly-increased cyclonic tangential wind is deflected by the Coriolis force to the right to form the upper-layer outflow accompanied by the central-area rising motion,leading to Haima's (2004) extratropical transition after its landfall.
文摘The aim of this study was to systematically review the evidence for the effectiveness of Buerger’s exercise on the peripheral circulation or diabetic foot ulceration. A systematic search and 18 electronic databases were conducted. The intervention was predominantly focused on Buerger’s exercise as an outcome. Due to high heterogeneity, data were synthesized in a narrative format rather than by statistical methods. Nine studies that covered 592 participants were selected in the analysis, of which 8 of the 9 found an effect of Buerger’s exercise on peripheral circulation. The positive effects were indicative of improving blood flow, walking ability, reducing necrosis, reducing venous embolism, pain, swelling, cyanosis and the bed-rest times. However, the study design and quality appraisal were limited to Jadad score 2 and the sample size was small. Findings provide some evidence of the beneficial effects of Buerger’s exercises. It was seen as a low cost and low risk physical activity that most diabetic patients could undertake at home. This review highlighted a need for further investigation of standardized procedures of Buerger’s exercises. More high quality studies on the prevention of diabetic foot are required regarding Buerger’s exercises.
文摘While China’s internal market potential is getting more and more tempting, Minister Zhang Haoruo of Internal Trade says in the years to come the retail, wholesale and material sectors will be freed up for foreign investment. Foreign businessmen will be welcome to compete in China. The Minister disclose "t that 11 cities had been approved to experiment
基金Supported by Medical University of Gda■sk,grant W-120,Poland
文摘AIM:Microcirculatory disturbances are important early pathophysiological events in various organs during acute pancreatitis.The aim of the study was to evaluate changes in microperfusion of the pancreas,liver,kidney,stomach, colon,skeletal muscle,and to investigate the influence of heparin on the organ microcirculation in caerulein-induced experimental acute pancreatitis. METHODS:Acute pancreatitis was induced by 4 intraperitoneal injections of caerulein(Cn)(15 μg/kg).The organ microcirculation was measured by laser Doppler flowmetry.Serum interleukin 6 and hematocrit levels were analysed. RESULTS:Acute pancreatitis resulted in a significant drop of microperfusion in all examined organs.Heparin administration(2×2.5 mg/kg)improved the microcirculation in pancreas(36.9±4% vs 75.9±10%),liver(56.6±6% vs 75.2±16%),kidney (45.1±6% vs 79.3±5%),stomach (65.2±8% vs 78.1±19%),colon(69.8±6% vs 102.5±19%), and skeletal muscle (59.2±6% vs 77.9±13%).Heparin treatment lowered IL-6(359.0±66 U/mL vs 288.5±58 U/mL) and hematocrit level(53±4% vs 46±3%). CONCLUSION:Heparin administration has a positive influence on organ microcirculatory disturbances accompanying experimental Cn-induced acute pancreatitis.
基金supported by the National Natural Science Foundation of China,Nos.82271447,81771382the National Key Research and Development Program of China,No.2019 YFE0115900the"New 20 Terms of Universities in Jinan,No.202228022 (all to ZZ)。
文摘α-Synuclein is a protein that mainly exists in the presynaptic terminals.Abnormal folding and accumulation of α-synuclein are found in several neurodegenerative diseases,including Parkinson’s disease.Aggregated and highly phospho rylated a-synuclein constitutes the main component of Lewy bodies in the brain,the pathological hallmark of Parkinson s disease.For decades,much attention has been focused on the accumulation of α-synuclein in the brain parenchyma rather than considering Parkinson s disease as a systemic disease.Recent evidence demonstrates that,at least in some patients,the initial α-synuclein pathology originates in the peripheral organs and spreads to the brain.Injection of α-synuclein preformed fibrils into the gastrointestinal tra ct trigge rs the gutto-brain propagation of α-synuclein pathology.However,whether α-synuclein pathology can occur spontaneously in peripheral organs independent of exogenous α-synuclein preformed fibrils or pathological α-synuclein leakage from the central nervous system remains under investigation.In this review,we aimed to summarize the role of peripheral α-synuclein pathology in the pathogenesis of Parkinson’s disease.We also discuss the pathways by which α-synuclein pathology spreads from the body to the brain.
文摘Symmetric circulant matrices (or shortly symmetric circulants) are a very special class of matrices sometimes arising in problems of discrete periodic convolutions with symmetric kernel. First, we collect major properties of symmetric circulants scattered through the literature. Second, we report two new applications of these matrices to isotropic Markov chain models and electrical impedance tomography on a homogeneous disk with equidistant electrodes. A new special function is introduced for computation of the Ohm’s matrix. The latter application is illustrated with estimation of the resistivity of gelatin using an electrical impedance tomography setup.
文摘The Xinjiang Production andConstruction Corps (XPCC) was foundedin October 1954. Since 1990, its plan hasbeen listed directly under the state councilof PRC.After 50 years of arduouspioneering and development, the XPCChas now developed to be a specialorganization with a solid economicstrength and enterprise group superiority,which is based on the large-scale andmodernized agriculture, and guided