With the modern advancement of treatment approaches in medical science, the application of biomaterials in tissue engineering provides a remarkable opportunity to overcome graft rejection as well as proper wound heali...With the modern advancement of treatment approaches in medical science, the application of biomaterials in tissue engineering provides a remarkable opportunity to overcome graft rejection as well as proper wound healing. In this study, novel hybrid films have been synthesized by incorporation of polyvinyl alcohol (PVA), gelatin, and gelatin with glycerin along with different concentrations of pre-prepared hydroxyapatite (HAP) by solution casting method at room temperature in a biosafety cabinet. Glutaraldehyde has been added as a crosslinker in this whole procedure. Fourier-transform infrared spectroscopy (FTIR), X-Ray Diffraction (XRD) have been conducted to observe and compare the structural and chemical stability of the synthesized hybrid film properties. The FTIR results and X-Ray Diffraction analyses confirmed the chemical interactions between HAP, PVA, gelatin, and glycerin have occurred. The crystallinity of HAP also remains in all the prepared hybrid film samples that are observed in XRD. It is expected that these newly synthesized hybrid films could be a better opportunity for various sectors of tissue engineering such as skin, bone, tendon, and cartilage. These synthesized hybrid films can be suitable for wound healing covering. These studies could be a new scope for long-term drug delivery directly on wound sites in diabetic gangrene foot or burn patients as well as cartilage or joint replacement therapy.展开更多
Microwave heating contributes to coal fracturing and gas desorption. However, problems of low penetration depth, local overheating and fracture closure exist. Coal demineralisation by acids has advantages in coal unbl...Microwave heating contributes to coal fracturing and gas desorption. However, problems of low penetration depth, local overheating and fracture closure exist. Coal demineralisation by acids has advantages in coal unblocking and permeability improvement, while it is difficult for acid to enter microcracks.Microwave-asisted acidification may offer an alternative. In this work, XRD,^(1)H-NMR, and SEM were used to evaluate the effect of microwave-assisted acidification on the microstructure of coal. Results show that kaolinite, calcite, and dolomite can be dissolved by acid. After microwave irradiation, the graphitization of microcrystalline structure of carbon improves. Microwave-assisted acidification erodes minerals in coal and enhances the graphitization degree of microcrystalline structure. Compared to individual microwave irradiation or acidification, the pore volume and pore connectivity can be greatly enhanced by microwave-assisted acidification. The NMR permeability of coal increased by 28.05%. This study demonstrates the potential of microwave-assisted acidification for coalbed methane recovery.展开更多
文摘With the modern advancement of treatment approaches in medical science, the application of biomaterials in tissue engineering provides a remarkable opportunity to overcome graft rejection as well as proper wound healing. In this study, novel hybrid films have been synthesized by incorporation of polyvinyl alcohol (PVA), gelatin, and gelatin with glycerin along with different concentrations of pre-prepared hydroxyapatite (HAP) by solution casting method at room temperature in a biosafety cabinet. Glutaraldehyde has been added as a crosslinker in this whole procedure. Fourier-transform infrared spectroscopy (FTIR), X-Ray Diffraction (XRD) have been conducted to observe and compare the structural and chemical stability of the synthesized hybrid film properties. The FTIR results and X-Ray Diffraction analyses confirmed the chemical interactions between HAP, PVA, gelatin, and glycerin have occurred. The crystallinity of HAP also remains in all the prepared hybrid film samples that are observed in XRD. It is expected that these newly synthesized hybrid films could be a better opportunity for various sectors of tissue engineering such as skin, bone, tendon, and cartilage. These synthesized hybrid films can be suitable for wound healing covering. These studies could be a new scope for long-term drug delivery directly on wound sites in diabetic gangrene foot or burn patients as well as cartilage or joint replacement therapy.
基金supported by the National Natural Science Foundation of China (Nos. 52274195, 52274196, 51904103, and 52174180)the Science and Technology Innovation Program of Hunan Province (No. 2022RC1178)+1 种基金Hunan Provincial Natural Science Foundation of China (Nos. 2022JJ20024, and 2021JJ30254)Scientific Research Foundation of Hunan Provincial Education Department (No. 21B0465)。
文摘Microwave heating contributes to coal fracturing and gas desorption. However, problems of low penetration depth, local overheating and fracture closure exist. Coal demineralisation by acids has advantages in coal unblocking and permeability improvement, while it is difficult for acid to enter microcracks.Microwave-asisted acidification may offer an alternative. In this work, XRD,^(1)H-NMR, and SEM were used to evaluate the effect of microwave-assisted acidification on the microstructure of coal. Results show that kaolinite, calcite, and dolomite can be dissolved by acid. After microwave irradiation, the graphitization of microcrystalline structure of carbon improves. Microwave-assisted acidification erodes minerals in coal and enhances the graphitization degree of microcrystalline structure. Compared to individual microwave irradiation or acidification, the pore volume and pore connectivity can be greatly enhanced by microwave-assisted acidification. The NMR permeability of coal increased by 28.05%. This study demonstrates the potential of microwave-assisted acidification for coalbed methane recovery.
