Objective To observe the efficacy difference of renal colic treated with electroacupuncture in comparison with intramuscular injection with Fortanodyn. Methods Fifty-one patients with renal colic were randomly divided...Objective To observe the efficacy difference of renal colic treated with electroacupuncture in comparison with intramuscular injection with Fortanodyn. Methods Fifty-one patients with renal colic were randomly divided into an electroacupuncture group （26 cases） and a medicine group （25 cases）. In the electroacupuncture group, electroacupuncture was applied to the Xi-cleft points of kidney and bladder meridians, named Shuǐquán （水泉 KI 5） and Jīnmén （金门 BL 63） as well as the relevant Front-mu points, Jīngmén （京门 GB 25） and Zhōngjí （中极 CV 3）. In the medicine group, intramuscular injection with Fortanodyn （100 mg） was administered. Once treatment was applied for immediate analgesia in each group. Before and after treatment, the Simplified McGill Pain Questionnaire （SF-MPQ） and the Visual Analogy Scale （VAS） were adopted for pain assessment respectively. The clinical efficacy and the recurrence of the disease were observed in the two groups. Results The clinically cured and remarkably effective rate was 69.2% （18/26） in the electroacupuncture group, which was superior to 44.0% （11/25） in the medicine group （P0.05）. Separately, in 10 min, 30 min, 60 min and 120 min after treatment, in either group, SF-MPQ and VAS scores were obviously reduced as compared with those before treatment （all P0.05）. The scores in 10 min and 30 min after treatment in the electroacupuncture group were reduced more remarkably as compared with those in the medicine group （both P0.05）. The complete remission time in the electroacupuncture group was shorter apparently than that in the medicine group [（131.19±152.12） min vs （184.29±84.04） min, P0.05]. The recurrence rate of renal colic in 24 h was 8.0% （2/25） in the electroacupuncture group, which was lower slightly than 31.6% （6/19） in the medicine group （P0.05）. Conclusion Renal colic can be effectively relieved in the treatment with either electroacupuncture at the Xi-cleft points and the Front-mu points of kidney and bladder meridians or intramuscular injection with Fortanodyn. But, the electroacupuncture therapy achieves much better efficacy.展开更多
目的观察针刺四关穴和郄穴联合蠲痹汤治疗膝骨关节炎的临床疗效及对患者关节疼痛和关节功能的影响。方法选取100例膝骨关节炎患者,随机分为对照组(50例)和观察组(50例)。对照组予口服蠲痹汤治疗,观察组在对照组治疗基础上联合针刺四关...目的观察针刺四关穴和郄穴联合蠲痹汤治疗膝骨关节炎的临床疗效及对患者关节疼痛和关节功能的影响。方法选取100例膝骨关节炎患者,随机分为对照组(50例)和观察组(50例)。对照组予口服蠲痹汤治疗,观察组在对照组治疗基础上联合针刺四关穴和郄穴治疗。比较两组临床疗效,比较两组治疗前后疼痛视觉模拟量表(visual analog scale,VAS)评分、西安大略与麦克马斯特大学骨关节炎指数(Western Ontario and McMaster Universities osteoarthritis index,WOMAC)评分和美国特种外科医院关节功能(Hospital for Special Surgery,HSS)评分,观察两组治疗前后骨代谢指标[血清骨钙素(osteocalcin,OC)和破骨细胞抑制因子(osteoclastogenesis inhibitory factor,OPG)]和炎症因子指标[血清白介素-6(interleukin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)和白介素-1(interleukin-1,IL-1)]的变化。结果观察组总有效率为94.0%,高于对照组的72.0%(P<0.05)。治疗后,两组VAS评分和WOMAC总分以及血清IL-6、TNF-α和IL-1水平均较治疗前降低(P<0.05),且观察组低于对照组(P<0.05);两组HSS评分以及血清OC和OPG水平均较治疗前升高(P<0.05),且观察组高于对照组(P<0.05)。结论针刺四关穴和郄穴联合蠲痹汤治疗膝骨关节炎可有效减轻患者膝关节疼痛,改善膝关节功能及骨代谢水平,降低炎症因子水平,疗效优于单一中药治疗。展开更多
文摘Objective To observe the efficacy difference of renal colic treated with electroacupuncture in comparison with intramuscular injection with Fortanodyn. Methods Fifty-one patients with renal colic were randomly divided into an electroacupuncture group （26 cases） and a medicine group （25 cases）. In the electroacupuncture group, electroacupuncture was applied to the Xi-cleft points of kidney and bladder meridians, named Shuǐquán （水泉 KI 5） and Jīnmén （金门 BL 63） as well as the relevant Front-mu points, Jīngmén （京门 GB 25） and Zhōngjí （中极 CV 3）. In the medicine group, intramuscular injection with Fortanodyn （100 mg） was administered. Once treatment was applied for immediate analgesia in each group. Before and after treatment, the Simplified McGill Pain Questionnaire （SF-MPQ） and the Visual Analogy Scale （VAS） were adopted for pain assessment respectively. The clinical efficacy and the recurrence of the disease were observed in the two groups. Results The clinically cured and remarkably effective rate was 69.2% （18/26） in the electroacupuncture group, which was superior to 44.0% （11/25） in the medicine group （P0.05）. Separately, in 10 min, 30 min, 60 min and 120 min after treatment, in either group, SF-MPQ and VAS scores were obviously reduced as compared with those before treatment （all P0.05）. The scores in 10 min and 30 min after treatment in the electroacupuncture group were reduced more remarkably as compared with those in the medicine group （both P0.05）. The complete remission time in the electroacupuncture group was shorter apparently than that in the medicine group [（131.19±152.12） min vs （184.29±84.04） min, P0.05]. The recurrence rate of renal colic in 24 h was 8.0% （2/25） in the electroacupuncture group, which was lower slightly than 31.6% （6/19） in the medicine group （P0.05）. Conclusion Renal colic can be effectively relieved in the treatment with either electroacupuncture at the Xi-cleft points and the Front-mu points of kidney and bladder meridians or intramuscular injection with Fortanodyn. But, the electroacupuncture therapy achieves much better efficacy.
文摘目的观察针刺四关穴和郄穴联合蠲痹汤治疗膝骨关节炎的临床疗效及对患者关节疼痛和关节功能的影响。方法选取100例膝骨关节炎患者,随机分为对照组(50例)和观察组(50例)。对照组予口服蠲痹汤治疗,观察组在对照组治疗基础上联合针刺四关穴和郄穴治疗。比较两组临床疗效,比较两组治疗前后疼痛视觉模拟量表(visual analog scale,VAS)评分、西安大略与麦克马斯特大学骨关节炎指数(Western Ontario and McMaster Universities osteoarthritis index,WOMAC)评分和美国特种外科医院关节功能(Hospital for Special Surgery,HSS)评分,观察两组治疗前后骨代谢指标[血清骨钙素(osteocalcin,OC)和破骨细胞抑制因子(osteoclastogenesis inhibitory factor,OPG)]和炎症因子指标[血清白介素-6(interleukin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)和白介素-1(interleukin-1,IL-1)]的变化。结果观察组总有效率为94.0%,高于对照组的72.0%(P<0.05)。治疗后,两组VAS评分和WOMAC总分以及血清IL-6、TNF-α和IL-1水平均较治疗前降低(P<0.05),且观察组低于对照组(P<0.05);两组HSS评分以及血清OC和OPG水平均较治疗前升高(P<0.05),且观察组高于对照组(P<0.05)。结论针刺四关穴和郄穴联合蠲痹汤治疗膝骨关节炎可有效减轻患者膝关节疼痛,改善膝关节功能及骨代谢水平,降低炎症因子水平,疗效优于单一中药治疗。
