Clinical Study on the Effectiveness of Xian Fang Huo Ming Yin for Treating Cutaneous Infections and Promoting Wound Healing in Patients with Perianal Abscess

Objective:To explore the effect of the Xian Fang Huo Ming Yin(XFHM)for treating cutaneous infections and promoting wound healing in patients with perianal abscesses.Methods:Sixty-one patients with perianal abscesses who were admitted to our hospital(Xinghua City People’s Hospital)from May 2022 to May 2023 were selected and randomly divided into two groups,a control group(30 cases)and a study group(31 cases).Both groups received surgical treatment.The control group received conventional treatment and warm water fumigation,sitz bath,and surgical dressing change after surgery,while the research group received XFHM based on the control group.XFHM was taken orally and replaced with warm water for fumigation and sitz bathing.Both groups received treatment for 4 weeks but discontinued sitz bathing after 2 weeks.Various clinical indicators between the two groups were compared.Results:The total clinical effective rate and wound recovery rate of the study group were higher than that of the control group.There were differences in the wound pain scores,surrounding tissue edema,and wound secretions at different time points.Both groups experienced wound pain.The scores of wound pain,surrounding tissue edema,and wound secretions of the study group were lower than those of the control group,7 and 14 days after surgery.The serum interleukin 6(IL-6),tumor necrosis factor-alpha(TNF-α)levels,and pH values of the study group were lower than those of the control group 10 days after surgery(P<0.05).Conclusion:The application of XFHM for treating cutaneous infections and promoting wound healing in patients with perianal abscesses improved the treatment outcome,alleviated clinical symptoms,and promoted healing.

仙方活命饮加减治疗溃疡性结肠炎(活动期)84例临床观察

目的:观察仙方活命饮加减治疗溃疡性结肠炎(活动期)临床疗效。方法:采用仙方活命饮加减口服治疗本病45例;并设对照组(美沙拉嗪肠溶片,口服)观察39例,疗程4 w。结果:治疗组证候疗效有效率84.44%,对照组为71.79%(P<0.05);治疗组肠镜疗效有效率75.56%,与对照组相似(P<0.05)。结论:仙方活命饮加减治疗溃疡性结肠炎(活动期)疗效明显,开拓了中医治疗该病的临床思路。

加味仙方活命饮治疗乳腺增生病临床观察

目的:观察加味仙方活命饮治疗乳腺增生病的临床疗效。方法:以加味仙方活命饮与乳康片进行对照观察。结果:加味仙方活命饮组总有效率91.7%,对照组为78.3%,疗效比较有非常显著性差异(P<0.01)。结论:加味仙方活命饮治疗肝郁化火、痰凝乳络证型乳腺增生病可取得较好疗效。

仙方活命饮的研究报告

我们用仙方活命饮治疗家畜患疮、癀、乳痈病62例,痊愈率为83.87％,总有效率为96.77％。此方针剂实验室试验:对大肠杆菌平均抑菌圈为16.95mm,对金色葡萄球菌平均抑菌圈为18.84mm,为极度敏感,对小白鼠腹腔巨噬细胞的吞噬百分比、被吞鸡红细胞总数、吞噬指数均有提高(P<0.01)。对兔白细胞总数、枝指数、淋巴细胞、单核细胞、T淋巴细胞增加。兔血清白蛋白减少,γ球蛋白增加。我们做伊文思蓝(即T—1824)渗出豚鼠皮肤试验,此方有降低毛细血管通透性、减少炎性物渗出的功能。

中药外用配合负压引流术(VSD)后游离植皮治疗下肢慢性溃疡30例临床观察

2013年11月～2015年6月本科采用中药外洗配合VSD负压引流术治疗下肢慢性溃疡30例,待创面肉芽新鲜,达到植皮条件后,采用植皮术,观察两种治疗方法对于控制感染及促进肉芽生长,达到植皮条件的疗效。

叶腾辉名老中医仙方活命饮临床治验

仙方活命饮是临床常用方剂,被前人称之为"疮疡之圣药,外科之首方"。叶老师取其清热解毒,活血止痛之法,应用本方对热毒壅盛、气血瘀滞引起的胃脘痛、淋证、痔疮进行治疗,收效良好。

槐花散联合仙方活命饮治疗溃疡性结肠炎临床研究

目的 评价槐花散联合仙方活命饮治疗溃疡性结肠炎的临床疗效.方法 将80例热毒炽盛型溃疡性结肠炎按照随机数字表法分为2组,每组40例.对照组口服美沙拉嗪肠溶片,观察组给予槐花散联合仙方活命饮.2组均治疗8周.采用ELISA法检测血清TNF-α、IL-8;采用Mayo疾病活动指数评价疾病的严重程度,评价临床疗效.结果 治疗后,观察组TNF-α[（66.11±3.72）ng/L比（92.61±4.32）ng/L,t=29.398]、IL-8[（53.11±2.72）ng/L比（69.31±1.32）ng/L,t=33.888]均低于对照组（P〈0.01）.观察组结肠镜像积分[（0.74±0.18）分比（1.25±0.49）分,t=6.179]、Mayo指数评分[（2.07±0.57）分比（3.30±0.93）分,t=7.132]均低于对照组（P〈0.01）.观察组总有效率为92.5%（37/40）、对照组为85.0%（34/40）,2组比较差异无统计学意义（χ2=1.127,P=0.288）.观察组复发率为5.4%（2/37）、对照组为26.5%（9/34）,2组比较差异无统计学意义（χ2=6.005,P=0.013）.结论 槐花散联合仙方活命饮可降低热毒炽盛型溃疡性结肠炎患者炎症因子水平,与口服美沙拉嗪肠溶片疗效相当.

仙方活命饮对小鼠免疫功能的影响

用1g/mL的仙方活命饮煎液0.2mL给健康小鼠灌胃7d,可促进腹腔巨噬细胞吞噬功能,提高外周血T淋巴细胞比率和淋巴细胞转化率,升高血清中溶血素含量,但对脾、胸腺重量无明显影响.该方对分别由环磷酰胺或地塞米松所致小鼠免疫功能的抑制有对抗作用,使上述5项免疫学指标维持正常或接近正常水平.由此认为,仙方活命饮作为中兽医治疗疮疡痈肿类疾病的优良方剂,其机理可能与该方可广泛增强机体非特异性和特异性免疫功能,并能对抗免疫抑制剂的作用,使机体免疫功能得到保护和调节有关.