Treatment of perianal infection in acute leukemia hematopoietic stem celltransplantation with Xiongzhen ointment mixed with furacilin powder

Objective： To investigate the effect of Xiongzhen ointment mixed with furaicillin powder on perianal care of patientswith acute myeloid leukemia M2a hematopoietic stem cell transplantation.Methods： A case of acute myeloid leukemia M2a hematopoietic stem cell transplantation was used as the research object.The method and effect of peristaltic nursing were recorded in the patients with hematopoietic stem cell transplantation byusing Xiongzhen ointment mixed with furazolidone powder.Results： After treatment with Xuelong ointment mixed with furacilin powder, the patients did not show obvious perianalinfection during the transplantation process. After 24 days, the transplant was successfully transferred into thetransitional ward.Conclusion： In the perianal care of laminar flow chamber, the addition of Xiongzhen ointment mixed with furaicillinpowder can reduce the incidence of perianal infection.

熊珍软膏联合碘伏预防急性白血病患者肛周感染的效果观察

目的探讨熊珍软膏+碘伏预防急性白血病患者肛周感染的效果。方法观察组采用碘伏擦洗肛周,然后涂抹熊珍软膏;对照组采用1∶5000高锰酸钾溶液坐浴,观察两组患者对两种方法的依从性及肛周感染发生率。结果观察组较对照组依从性高,肛周感染发生率明显降低,两组间有统计学意义。结论熊珍软膏+碘伏擦拭预防急性白血病患者肛周感染有效,依从性优于用高锰酸钾溶液坐浴,是预防肛周感染简便、经济有效的方法之一,值得临床推广应用。

熊珍膏对大鼠CRP及TNF-ɑ的调节作用及对皮肤创面愈合影响的实验研究

目的:观察熊珍膏在大鼠皮肤创面愈合过程中对大鼠血清CRP及TNF-ɑ的干预情况,探讨其抗炎及促进创面愈合的作用机理。方法:建立大鼠皮肤创面模型后分为4组,模型组、贝复济对照组(西药组)、熊珍膏组(中药组)、熊珍膏+贝复济组(中西组)各18只。各创面给予相应药物;每日定时换药2次。于造模后第3、7、14天取材,采用双抗体夹心ABC-ELISA法检测大鼠血清中CRP变化情况;采用双抗体夹心ABC-ELISA法检测大鼠血清TNF-ɑ变化情况。实验所得数据均采用-x±s表示,所有结果采用SPSS18.0统计软件进行统计学处理。结果:熊珍膏可以显著降低模型大鼠血清CRP水平,且与中西组无差异;熊珍膏可以显著降低模型大鼠血清TNF-ɑ水平,且与中西组无差异。结论:熊珍膏促进大鼠皮肤切口创面的愈合其机制可能与降低了CRP及TNF-ɑ水平,减少炎症反应有关。