School of Chemical and Biological Science and Engineering of YTU

The school consists of four first-level interdisciplines： chemistry, biological science, chemical engineering and technology, and food science and engineering. There are three basic teaching divisions： chemistry, biological science and chemical engineering; four research institutes： biological science and technology, food science and technology, chemical materials, and applied chemistry; four basic experimental teaching centers： biology, chemistry, chemical engineering and technique, and food science and engineering; and one food quality and safety testing and detecting center.

归芎益母散治疗奶牛血瘀型胎衣不下的扩大临床试验研究

在实验性临床研究基础上,进一步验证归芎益母散推荐有效剂量400 g/头治疗奶牛血瘀型胎衣不下的临床疗效。将纳入研究的193头血瘀型奶牛随机分为2组,其中药物对照组96头和归芎益母散组97头,以滞留胎衣排出为主要疗效评价指标,以受试奶牛产褥期子宫炎继发感染率和产后180 d内繁育性能为次要疗效评价指标,综合评价归芎益母散的临床效果。与阳性药物对照组比较,归芎益母散组中受试奶牛的首次给药72 h内滞留胎衣排出率提高(89.7%vs.72.9%,P<0.01),一次给药滞留胎衣排出率提高(70.7%vs.50.0%,P=0.013),而给药次数减少(1.7±0.9 vs.2.0±1.4,P<0.05);产褥期子宫炎感染率降低(15.5%vs.24.0%,P<0.01),同时可提高受试奶牛的繁育性能,包括产后首次配种时间提前(66.6±19.1 d vs.78.7±25.6 d,P<0.01),首次配种怀孕率提高(70.6%vs.26.4%,P<0.01),配种次数降低(1.8±1.3 vs.2.6±1.3,P<0.01),产后180 d内总怀孕率提高(90.6%vs.71.9%,P<0.01),同时空怀时间缩短(87.3±42.7 d vs.120.9±47.3 d,P<0.01)。试验期间未发现药物相关不良反应。以归芎益母散推荐有效剂量(400 g/头)治疗奶牛血瘀型胎衣不下,可有效促进滞留胎衣排出,降低产褥期子宫炎的发生风险,并能有效改善患牛的繁育性能,临床疗效确切,安全性好。