Analysis of fibronectin, fibronectin receptor and interleukin 1 in patients with cirrhosis treated by Yanggan Jieyu decoction

AIM To investigate the adjusting effects of the Yanggan Jieyu (YGJY, nourishing the liver and alleviate mental depression) decoction on the plasma concentration of fibronectin (FN), fibronectin receptor (FNR), tumor necrosis factor alpha (TNF α) and the activity of interleukin 1 (IL 1) in patients with cirrhosis. METHODS Thirty four cases of cirrhosis (in decompensation) were divided into YGJY decotion treated group and control group treated by routine method. FN, FNR and TNF α were measured with ELESA and expressed as mg/L (FN, FNR) and ng/L (TNF α), and IL 1 was measured by mice thymocyte proliferation using β scintillation counter and expressed as cpm. RESULTS In YGJY decoction treated group, before treatment, FN was 247 9±97 2, FNR 5 6±2 7, TNF α 83 9±7 1 and IL 1 was 2760 8±813 6, and after treatment. FN was 298 3±93 2 ( P <0 01), FNR 4 3±2 3 ( P <0 05, TNF α 93 6±12 0 ( P <0 05) and IL 1 was 1922 3±847 0 ( P <0 05). The FN and TNF α plasma level after treatment increased remarkably, while FNR and IL 1 decreased obviously. In the control group before treatment, FN was 248 8±101 9, FNR 5 5±1 9, TNF α 126 1±48 1 and IL 1 was 2540 6±603 2, and after treatment was 241 6±77 1 ( P >0 05), FNR 5 4±1 2 ( P >0 05), TNF α 100 6±15 5 ( P >0 05) and IL 1 was 2360 6±860 0 ( P >0 05), the plasma levels of FN, TNF α, FNR and IL 1 did not change signifiantly. CONCLUSION YGJY decoction could prevent the process of the hepatic fibrosis by readjusting the plasma levels of FN, FNR, TNF α and IL 1 mediating acivities in cirrhosis, which is of clinical significance.

Delicious Food in Nanyang-Xinye Board Noodles

Nanyang,a city with a long history,offers many kinds of delicious food.Xinye board noodles stand out as a remarkable(显著的)one.With unique taste and local features,they have become a significant(重要的)symbol of Nanyang cuisine.

Influence of Chinese and Western Culture on Modern Church Architecture in Yan’an Area

Based on the historical records and field investigation, this paper aims at elaborating the architectural styles, interior space design and architectural landscape of modern church architecture in Yan’an, analyzing the influence of Chinese and western culture on modern church architecture in Yan’an and expounding the historical and cultural value as church architecture, which will play a great role in the protection, inheritance and utilization of modern architecture in Yan’an area.

Breeding and Application of Indica PTGMS Line Yan 220S in Rice

Yan 220S, which is derived from a natural variant plant discovered among the population of Guangzhan 63S and developed by Jiangsu Agricultural Research Institute for Coastal Regions through pedigree selection over years, is an indica photo- and thermo-sensitive genic male sterile （PTGMS） line in rice. In 2013, it was technically identified by Jiangsu Crop Variety Appraisal Committee. Its hybrid Yan-liangyou 2208 （Yan 220S/Yanhui 888）, a new two-line hybrid rice combination with high yield and good grain quality, was subsequently developed and released for commercial production by the National Crop Variety Appraisal Committee in 2013.

Breeding and Application of Indica PTGMS Line Yan 161S and Its Hybrid Yanliangyou 1618 in Rice

In 2006, the indica photoperiod- and thermo-sensitive genic male sterile （PTGMS） line Yan 161S was successful y bred by crossing the Guangzhan 63S （♀） and the medium indica breeding material Yan 229 （♂）, which was bred by the Institute of Agricultural Sciences in Coastal Region of Jiangsu Province, after years＇ and generations’ selection in different areas. It passed the identification by Jiangsu Provincial Crop Variety Appraisal Committee in 2013. Crossing the Yan 161S with Yanhui 888, a new high-yielding and high-quality two-line hybrid rice combination Yanliangyou 1618 was developed, and it passed the variety identification in 2014. This paper introduced the breeding processes and characteristics of Yan 161S and Yanliangyou 1618 and the cultivation and seed production techniques of Yanliangyou 1618.

The Relationship between Jurassic Coal Measures and Sandstone-type Uranium Deposits in the Northeastern Ordos Basin,China

Outcrop and drill hole data show that the Jurassic coal measures in the northeastern Ordos Basin are composed mainly of the Yan’an Formation and the lowstand system tract of the Zhiluo Formation, and there is a regional unconformity between them. The Dongsheng uranium deposit is associated with the Jurassic coal measures. Research data indicate that the Jurassic coal measures in the study area have a certain hydrocarbon-generating capacity, although the metamorphic grade is low （Ro=0.40%–0.58%）. In the Dongsheng region alone, the accumulative amount of generated coalbed methane （CBM） is about 2028.29 × 108 –2218.72 × 108 m3; the residual amount is about 50.92 × 108 m3, and the lost amount is about 1977 × 108 m3. Analysis of the burial history of the host rocks and the evolutionary history of the Dongsheng uranium deposit suggests that the Jurassic coal measures generated hydrocarbon mainly from Middle Jurassic to Early Crataceous, which is the main mineralization phase of the Dongsheng uranium deposit. By the Late Cretaceous, a mass of CBM dissipated due to the strong tectonic uplift, and the Dongsheng uranium deposit stepped into the preservation phase. Therefore, the low-mature hydrocarbon-containing fluid in the Jurassic coal measures not only served as a reducing agent for the formation of sandstone-type uranium deposits, but also rendered the second reduction of paleo-interlayer oxidation zone and become the primary reducing agent for ore conservation. Regional strata correlation reveals that the sandstone-type uranium reservoir at the bottom of the Zhiluo Formation is in contact with the underlying industrial coal seams in the Yan’an Formation through incision or in the form of an unconformity surface. In the Dongsheng region with poorly developed fault systems, the unconformity surface and scour surface served as the main migration pathways for low-mature hydrocarbon-containing fluid migrating to the uranium reservoir.

Seed Selection and Application of New Hemerocallis ‘Jin-yan'

It is to introduce seed selection and main points of cultivation technology for new Hemerocallis'jin yan'. We selected some quality resources from 300 types of domestic and foreign seed,carried out the seed resistance experiment. From comparison of parent strain and filial generation in agronomic traits,ornamental traits,and stress resistance,we obtained special traits of Hemerocallis'jin yan'. Flower diameter of'jin yan' is larger than that of parent strain; seed stalk is higher than parent strain; it inherited evergreen feature of parent strain; the flower color is brighter than parent strain; the flowering stage is about 45 days,and it has reflowering phenomenon; in winter,it keeps evergreen; it is high in stress resistance,and suitable for planting in Yangtze River Delta region. The new Hemerocallis'jin yan'has high afforestation and promotional value in Yangtze River Delta region.

Protective Effects of Jin Bai Mei Yan Prescription on Oxidative Damage and Photoaging Induced by Ultraviolet B in HaCaT Cells

Objective Ultraviolet B(UVB)mainly acts on the skin epidermis,causing oxidative damage and apoptosis of keratinocytes.Jin Bai Mei Yan Prescription(JBMYP)comprises a variety of antioxidant traditional Chinese medicines(TCM).In this study,we aimed to evaluate the effects of JBMYP on the oxidative damage induced by UVB in human immortalized epidermal keratinocytes(HaCaT)cells.Methods HaCaT cells were divided into six groups:control group,model(UVB)group,positive(UVB+vitamin E)group,UVB+JBMYP low dose group(160μg/mL),UVB+JBMYP moderate dose group(800μg/mL),and UVB+JBMYP high dose group(1600μg/mL).HaCaT cells were irradiated with UVB and treated with JBMYP for 24 h.Methyl thiazolyl tetrazolium(MTT)assay and real-time unlabeled cell function analyzer were used to assess the cell survival and proliferation rates,respectively.At the same time,the levels of intracellular reactive oxygen species(ROS),lipid peroxide malondialdehyde(MDA),glutathione(GSH),and hydroxyproline(HYP),as well as the activities of antioxidant enzyme superoxide dismutase(SOD)and catalase(CAT)were evaluated using enzyme linked immunosorbent assay(ELISA).Results Compared with the model group,the survival rate of HaCaT cells in each dosage group of JBMYP was significantly improved(P<0.05).Further,JBMYP could promote the proliferation of HaCaT cells,leading to a reduction in the contents of MDA and ROS,and increase in the contents of SOD,CAT,GSH and HYP in HaCaT cells.Conclusions JBMYP has enhanced protective effect on oxidative damage induced by UVB in HaCaT cells.

EXPERIMENTAL AND CLINICAL STUDIES OF “SHEN YAN LING” IN TREATMENT OF CHRONIC GLOMERULONEPHRITIS

“Shen Yan Ling”(SYL 肾炎灵) is a compoundherbal preparation consisting of 16 ingredients:HerbaEcliptae,Radix Rhemanniae,Rhizoma Cibotii,RadixAngelica Sinensis,Rhizoma Ligustici Chuanxiong,Radix Paeoniac Rubra,Rhizoma Diosocoreae,Poria,Radix Sanguisorbae,Radix Rubiae,Herba Portulacae,Fructus Gardeniae,Herba Cirsii Japonici,HerbaCephalanoploris.etc.In animal experiments,SYLwas shown to have therapeutic effect for Masugi’snephritis models.It has also been used with satis-factory results in the treatment of 314 cases of chronicglomerulonephritis of the common type with manifes-tations of Yin deficiency and endogenous heat.

A study of TCM master Yan Zhenghua’s medication rule in prescriptions for digestive system diseases based on Apriori and complex system entropy cluster

Objective:To explore Yan Zhenghua’s drug selection rule for treating digestive system diseases using data mining.Methods:The 609 medical records of digestive system diseases treated by Yan Zhenghua were collected and the herbs in these recipes were examined using a data mining technique.The correlativity between herb pairs and association rules was studied using an Apriori algorithm and the correlativity among multi-herbs was studied using a complex system entropy cluster technique.Results:Yan Zhenghua’s treatment of digestive system diseases featured 15 herbs prescribed at least 159 times each,22 herb pairs prescribed at least 155 times each,and eight frequently used herb core combinations.A confidence greater than 0.91 and a support level greater than 20%were achieved using the modified mutual information method.Conclusion:The data mining results conformed to findings from clinical practice.The data mining method is a valuable technique with which to study the experience of famous,elderly traditional Chinese medicine physicians.

Research Advance in the Efficacy and Mechanism of Qing Fei Xiao Yan Wan for the Treatment of Respiratory Diseases

Qing Fei Xiao Yan Wan had been incorporated into the existing “Chinese Pharmacopoeia”, protected by patents. The manufacturing process of it was scientific and its compatibility was reasonable. It was also shown by clinical trials that the efficacy is exact. Clinical trials and experiment studies had confirmed the efficacy and some mechanism for the treatment of respiratory diseases, which were summaried in this paper. Combined with the experimental results (published in another paper), the other prospect application was further discussed.

Tuo Shan Yan Dam and City Ningbo： Exploring the Historical Logic of Urban Water Management through a Big City of China

Tuo Shan Yan Dam is a small darn which was built above Yinjiang River at the Yinjiang Town, Ningbo City, Zhejiang Province of China in 833 AD, but it is greatly contributed to Ningbo City, a current big port city of China. The dam and the matched system had become a key hydro-infrastructure to the city＇s existence and development, and irrigation of the countryside nearby the city from ninth century up to 1987, a big dam was built at upper reach to control water of the river. Tuo Shan Yan Dam functioned an important role in the local water management and met a series of purposes perfectly, mainly as： （a） regulation of the river water; （b） save the flood; （c） stop the salinization; （d） urban water supply; （e） storage of flesh water; （f） irrigation; （g） ship transportation. And it is a miracle that it has been functioned for more than one thousand years. This dam also influenced the local social life and people＇s spiritual world simultaneously. The construction of the dam and its matched hydro-system is in line with the Chinese ancient logic of urban water management to manage river to meet a multi-proposes of urban development by a key project and a systemic engineering design. It is an important case for better understanding of ancient Chinese urban water management and to learn from the history for current water sustainability. Accordingly, the dam＇s design, construction and its influence on the local societies are studied in this article.

When History Becomes A Standing Joke：Mo Yan＇s Reflection on China＇s Historical Changes Throughout the 20th Century

Since the end of the 20th century, Mo Yan has made an attempt to reflect on China＇s historical changes throughout the 20th century as a whole. Centered on such several novels as Big Breasts and Wide Hips, Life and Death Are Wearing Me Out and Frog, this paper explores the author＇s thinking of the interruption and repetition phenomena in China＇s 20th century history. Differing from viewing the history in a modem linear progressive perspective, Mo Yan regards the interruption of history as a sign of human degradation, which derives from the loss of folk history subjectivity. When history is treated rudely, its repetition will occur, and the one who treats history as laughingstocks will be written into history as part of a ＂farce＂.

The Origin of the“Cultural Strategy”Perspective in Yan’an Literature and Art Research

The field relationship of literature in the Yan’an period is the first thing worthy of attention.In order to become an independent literary history,the literature of Yan’an period must be able to be distinguished from“Sui literary literature”and“new Chinese literature”.The complex field relationship in the Yan’an period makes the“cultural strategy”an indispensable perspective for studying literature in this period.

New Ways to Deepen Reform in Foreign Trade Enterprises An interview with Yan Junxiu, General Manager of the Beijing Garment I/E shareholding Corp.

The Beijing Garment Import and Export Shareholding Corporation, Ltd. was the first shareholding corporation in Beijing which was set up in February 18, 1994. Its predecessor, the Beijing Garment Import and Export Corporation, had registered annual import and export earnings of US$300 million, ranking first among the foreign trade corporations in Beijing. Its change into a shareholding corporation has aroused keen interest in garment

Peking University Campus:From Ruined Garden to Yan Yuan

The current location of Peking University used to be the campus of Yenching University which was called Yan Yuan. It is situated in the northwestern suburb of Beijing, neighboring the well-known Qing-Dynasty imperial resorts "Summer Palace" and "Fragrant Hill" and the celebrated Tsinghua University.With the naturally endowed landscape, the northwest of Beijing became famous as ideal scenic resorts as early as 800 years ago. During the Ming and Qing dynasties, a cluster of imperial and private gardens were built on the site of