This paper reports the effects of the Yh^(3+) and its four complexes on cultured cells.The results indicate that the 5 mmol YbCl_3 has evident toxicity on cultured cells,and after it is coordinated with ligands,its to...This paper reports the effects of the Yh^(3+) and its four complexes on cultured cells.The results indicate that the 5 mmol YbCl_3 has evident toxicity on cultured cells,and after it is coordinated with ligands,its toxicity is decreased.These.four complexes neither destroy the growth nor inhibit the adliesion of diploid cell to the surface of the flasket,but they inhibit the adhesion of cancer cells,and result in cell death.The complex of Yb~?(3+) with ligand(1) can destroy the cancer cells in division phase.forming aberrant mitotic cells,but the other three complexes of Yb^(3+) with ligands can destroy the cancer cells in interphase.These effects depend on the dose of the complex.展开更多
Yb 3+ complexes with two nitrilotriacetic acid molecules were prepared and their compositions were determined as K 3[Yb(nta) 2(H 2O)]·5H 2O and Na 3[Yb(nta) 2]·6H 2O by elemental analyses. Their structures w...Yb 3+ complexes with two nitrilotriacetic acid molecules were prepared and their compositions were determined as K 3[Yb(nta) 2(H 2O)]·5H 2O and Na 3[Yb(nta) 2]·6H 2O by elemental analyses. Their structures were characterized by single crystal X ray diffraction analyses. In complex K 3[Yb(nta) 2(H 2O)]·5H 2O, the YbN 2O 7 part forms a nine coordinate monocapped square antiprismatic structure. In complex Na 3[Yb(nta) 2]·6H 2O, the YbN 2O 6 part forms an eight coordinate square antiprismatic structure. It can be seen that the outer cations (K + and Na +) greatly affect the coordination number and coordinate structure from these results.展开更多
A new Cd（II） complex [Cd（C12H6OaN2）（Phen）ffH2O）]＇3H2O with 2,2＂-bipyridine- 3,3＂-dicarboxylic acid as a ligand has been synthesized. Crystal data for the title complex are as follows： monoclinic, space grou...A new Cd（II） complex [Cd（C12H6OaN2）（Phen）ffH2O）]＇3H2O with 2,2＂-bipyridine- 3,3＂-dicarboxylic acid as a ligand has been synthesized. Crystal data for the title complex are as follows： monoclinic, space group P2dn, a = 12.8458（5）, b = 17.9131（7）, c = 15.2960（6） A, β = 111.7430（10）°, V = 3269.3（2） A3, Dc = 1.581 g/cm3, Z = 4,/a（MoKa） = 0.731 mm-1, F（000） = 1580, the R = 0.0244 and wR = 0.0605. In the title complex, the central Cd（ll） ion is located in a distorted octahedral coordination environment. The electrochemical and fluorescent properties of the title complex were studied. The results show that the electron transfer of the title complex is irreversible in the electrode reaction and it has a broad emission peak in the range of 470-508 nm with the excitation wavelength of 488 nm.展开更多
A dinuclear copper complex [Cu2LCl2]（ClO4）2 （L = 2,2＇-（piperazine-1,4-diyl）bis- （N,N-bis（pyridine-2-ylmethyl）ethan-1-amine）） has been synthesized and structurally characterized. It crystallizes in triclinic...A dinuclear copper complex [Cu2LCl2]（ClO4）2 （L = 2,2＇-（piperazine-1,4-diyl）bis- （N,N-bis（pyridine-2-ylmethyl）ethan-1-amine）） has been synthesized and structurally characterized. It crystallizes in triclinic, space group Pī with α = 8.5707（9）, b = 10.5083（12）, c = 11.4878（13） A, α = 76.197（2）, β = 88.271（2）, γ = 87.855（2）o, V = 1003.81（19） A3, Z = 1, F（000） = 478, Dc = 1.544 Mg/m3, Mr = 933.60, μ = 1.383 mm^-1, the final R = 0.0669 and wR = 0.1486 for 3675 observed reflections with I 〉 2σ（I）. Its catechol oxidase mimic activity was studied spectroscopically by using 3,5-di-tert-butylcatechol （3,5-DTBC） as the substrate. The results showed that the kinetics of catechol catalyzed by the complex accorded with the Michaelis-Mentent equation, and the catechol oxidase catalytic activity of the complex increased with increasing the pH values.展开更多
经过三步反应合成了红色晶体,双六甲基二硅胺基二甲基硅基环戊二烯基稀土二价镱配合物[η5-C5H4S iM e2N(S iM e3)2]2Yb(Ⅱ).2THF,X射线衍射结果表明,[η5-C5H4S iM e2N(S iM e3)2]2Yb(Ⅱ).2THF属于单斜晶系,空间群为P21/c,a=1.646 87(1...经过三步反应合成了红色晶体,双六甲基二硅胺基二甲基硅基环戊二烯基稀土二价镱配合物[η5-C5H4S iM e2N(S iM e3)2]2Yb(Ⅱ).2THF,X射线衍射结果表明,[η5-C5H4S iM e2N(S iM e3)2]2Yb(Ⅱ).2THF属于单斜晶系,空间群为P21/c,a=1.646 87(12)nm,b=0.907 70(6)nm,c=3.049 4(3)nm,β=93.642(4),°V=4.549 3(6)nm3,Z=2,C34H72N2O2S i6Yb,Mr=1 905.41,Dc=1.288 g/cm3,F(000)=1 840.00,μ(MoKα)=22.42 cm-1(λ=0.071 070 nm)。收集独立衍射点7 814个,将其中I>3.00σ(1)的用于结构解析,用全矩阵最小二乘法校正,得最终偏离因子R=0.039,Rw=0.050。8配位的中心镱原子与2个四氢呋喃的氧及2个环戊二烯基配位形成扭曲的四面体结构。展开更多
文摘This paper reports the effects of the Yh^(3+) and its four complexes on cultured cells.The results indicate that the 5 mmol YbCl_3 has evident toxicity on cultured cells,and after it is coordinated with ligands,its toxicity is decreased.These.four complexes neither destroy the growth nor inhibit the adliesion of diploid cell to the surface of the flasket,but they inhibit the adhesion of cancer cells,and result in cell death.The complex of Yb~?(3+) with ligand(1) can destroy the cancer cells in division phase.forming aberrant mitotic cells,but the other three complexes of Yb^(3+) with ligands can destroy the cancer cells in interphase.These effects depend on the dose of the complex.
基金Supported by the Natural Science Fund of L iaoning Province and Shenyang City Science and Technology Comm ittee
文摘Yb 3+ complexes with two nitrilotriacetic acid molecules were prepared and their compositions were determined as K 3[Yb(nta) 2(H 2O)]·5H 2O and Na 3[Yb(nta) 2]·6H 2O by elemental analyses. Their structures were characterized by single crystal X ray diffraction analyses. In complex K 3[Yb(nta) 2(H 2O)]·5H 2O, the YbN 2O 7 part forms a nine coordinate monocapped square antiprismatic structure. In complex Na 3[Yb(nta) 2]·6H 2O, the YbN 2O 6 part forms an eight coordinate square antiprismatic structure. It can be seen that the outer cations (K + and Na +) greatly affect the coordination number and coordinate structure from these results.
基金Fund of Science and Technology Committee of Hunan Province(No.2012GK3030)Scientific Research Fund of Hunan Provincial Education Department(No.11C0186)+1 种基金Hengyang Bureau of Science and Technology(No.2011kG28)the Key Discipline Project of Hunan Province
文摘A new Cd（II） complex [Cd（C12H6OaN2）（Phen）ffH2O）]＇3H2O with 2,2＂-bipyridine- 3,3＂-dicarboxylic acid as a ligand has been synthesized. Crystal data for the title complex are as follows： monoclinic, space group P2dn, a = 12.8458（5）, b = 17.9131（7）, c = 15.2960（6） A, β = 111.7430（10）°, V = 3269.3（2） A3, Dc = 1.581 g/cm3, Z = 4,/a（MoKa） = 0.731 mm-1, F（000） = 1580, the R = 0.0244 and wR = 0.0605. In the title complex, the central Cd（ll） ion is located in a distorted octahedral coordination environment. The electrochemical and fluorescent properties of the title complex were studied. The results show that the electron transfer of the title complex is irreversible in the electrode reaction and it has a broad emission peak in the range of 470-508 nm with the excitation wavelength of 488 nm.
基金financially supported by the National Natural Science Foundation of China(51173060)
文摘A dinuclear copper complex [Cu2LCl2]（ClO4）2 （L = 2,2＇-（piperazine-1,4-diyl）bis- （N,N-bis（pyridine-2-ylmethyl）ethan-1-amine）） has been synthesized and structurally characterized. It crystallizes in triclinic, space group Pī with α = 8.5707（9）, b = 10.5083（12）, c = 11.4878（13） A, α = 76.197（2）, β = 88.271（2）, γ = 87.855（2）o, V = 1003.81（19） A3, Z = 1, F（000） = 478, Dc = 1.544 Mg/m3, Mr = 933.60, μ = 1.383 mm^-1, the final R = 0.0669 and wR = 0.1486 for 3675 observed reflections with I 〉 2σ（I）. Its catechol oxidase mimic activity was studied spectroscopically by using 3,5-di-tert-butylcatechol （3,5-DTBC） as the substrate. The results showed that the kinetics of catechol catalyzed by the complex accorded with the Michaelis-Mentent equation, and the catechol oxidase catalytic activity of the complex increased with increasing the pH values.
基金supported by the National Natural Science Foundation of China(21573196,J1210042)Program for Zhejiang Leading Team of S&T Innovation(2011R50007)+1 种基金National High Technology Research and Development Program of China(863)(SS2015AA020601)Fundamental Research Funds of the Central Universities,China~~
