目的探讨血清CC趋化因子配体20(CCL20)及白介素-17(IL-17)水平与子痫前期的相关性及其对子痫前期的诊断效能。方法选择2021年1月至2022年12月陕西省人民医院产科收治的150例子痫前期孕妇为子痫前期组,另选取同期90例健康妊娠妇女为对照...目的探讨血清CC趋化因子配体20(CCL20)及白介素-17(IL-17)水平与子痫前期的相关性及其对子痫前期的诊断效能。方法选择2021年1月至2022年12月陕西省人民医院产科收治的150例子痫前期孕妇为子痫前期组,另选取同期90例健康妊娠妇女为对照组。采用酶联免疫吸附法(ELISA)检测血清CCL20及IL-17的表达水平,采用Pearson相关法分析血清CCL20及IL-17与子痫前期患者临床参数的相关性;采用受试者工作特征曲线(ROC)分析血清CCL20及IL-17对子痫前期的诊断价值。结果子痫前期组孕妇血清CCL20及IL-17水平均显著高于对照组(P<0.001)。子痫前期组孕妇血清CCL20及IL-17的表达均与收缩压(分别为r=0.463、r=0.545)、舒张压(分别为r=0.475、r=0.467)及尿蛋白(分别为r=0.302、r=0.342)呈显著正相关(P<0.001),而与终止妊娠孕周(分别为r=-0.281、r=-0.188)、新生儿出生体重(分别为r=-0.299、r=-0.200)及1 min Apgar评分(分别为r=-0.215、r=-0.194)呈显著负相关(P<0.05)。子痫前期组孕妇血清CCL20与IL-17水平呈显著正相关(r=0.615,P<0.001)。血清CCL20及IL-17诊断子痫前期的临界值分别为50.025 pg/ml及48.825 pg/ml,血清CCL20+IL-17联合诊断子痫前期的曲线下面积最大,灵敏度及特异度分别为87.3%及94.4%。结论子痫前期孕妇血清CCL20及IL-17的水平显著高于健康孕妇,且CCL20及IL-17水平与患者的血压、尿蛋白、妊娠结局及新生儿情况均存在显著相关性,两指标联合应用对子痫前期有一定的诊断价值。展开更多
Various features of the atmospheric environment affect the number of migratory insects, besides their initial population. However, little is known about the impact of atmospheric low-frequency oscillation(10 to 90 day...Various features of the atmospheric environment affect the number of migratory insects, besides their initial population. However, little is known about the impact of atmospheric low-frequency oscillation(10 to 90 days) on insect migration. A case study was conducted to ascertain the influence of low-frequency atmospheric oscillation on the immigration of brown planthopper, Nilaparvata lugens(Stl), in Hunan and Jiangxi provinces. The results showed the following:(1) The number of immigrating N. lugens from April to June of 2007 through 2016 mainly exhibited a periodic oscillation of 10 to 20 days.(2) The 10-20 d low-frequency number of immigrating N. lugens was significantly correlated with a low-frequency wind field and a geopotential height field at 850 h Pa.(3) During the peak phase of immigration, southwest or south winds served as a driving force and carried N. lugens populations northward, and when in the back of the trough and the front of the ridge, the downward airflow created a favorable condition for N. lugens to land in the study area. In conclusion, the northward migration of N. lugens was influenced by a low-frequency atmospheric circulation based on the analysis of dynamics. This study was the first research connecting atmospheric low-frequency oscillation to insect migration.展开更多
文摘目的探讨血清CC趋化因子配体20(CCL20)及白介素-17(IL-17)水平与子痫前期的相关性及其对子痫前期的诊断效能。方法选择2021年1月至2022年12月陕西省人民医院产科收治的150例子痫前期孕妇为子痫前期组,另选取同期90例健康妊娠妇女为对照组。采用酶联免疫吸附法(ELISA)检测血清CCL20及IL-17的表达水平,采用Pearson相关法分析血清CCL20及IL-17与子痫前期患者临床参数的相关性;采用受试者工作特征曲线(ROC)分析血清CCL20及IL-17对子痫前期的诊断价值。结果子痫前期组孕妇血清CCL20及IL-17水平均显著高于对照组(P<0.001)。子痫前期组孕妇血清CCL20及IL-17的表达均与收缩压(分别为r=0.463、r=0.545)、舒张压(分别为r=0.475、r=0.467)及尿蛋白(分别为r=0.302、r=0.342)呈显著正相关(P<0.001),而与终止妊娠孕周(分别为r=-0.281、r=-0.188)、新生儿出生体重(分别为r=-0.299、r=-0.200)及1 min Apgar评分(分别为r=-0.215、r=-0.194)呈显著负相关(P<0.05)。子痫前期组孕妇血清CCL20与IL-17水平呈显著正相关(r=0.615,P<0.001)。血清CCL20及IL-17诊断子痫前期的临界值分别为50.025 pg/ml及48.825 pg/ml,血清CCL20+IL-17联合诊断子痫前期的曲线下面积最大,灵敏度及特异度分别为87.3%及94.4%。结论子痫前期孕妇血清CCL20及IL-17的水平显著高于健康孕妇,且CCL20及IL-17水平与患者的血压、尿蛋白、妊娠结局及新生儿情况均存在显著相关性,两指标联合应用对子痫前期有一定的诊断价值。
基金National Science Foundation of China(41075086,41475106)Science Research Program of Universities and Colleges in Jiangsu Province(14KJA170003)Priority Academic Program Development of Jiangsu Higher Education Institutions(IRT1147)
文摘Various features of the atmospheric environment affect the number of migratory insects, besides their initial population. However, little is known about the impact of atmospheric low-frequency oscillation(10 to 90 days) on insect migration. A case study was conducted to ascertain the influence of low-frequency atmospheric oscillation on the immigration of brown planthopper, Nilaparvata lugens(Stl), in Hunan and Jiangxi provinces. The results showed the following:(1) The number of immigrating N. lugens from April to June of 2007 through 2016 mainly exhibited a periodic oscillation of 10 to 20 days.(2) The 10-20 d low-frequency number of immigrating N. lugens was significantly correlated with a low-frequency wind field and a geopotential height field at 850 h Pa.(3) During the peak phase of immigration, southwest or south winds served as a driving force and carried N. lugens populations northward, and when in the back of the trough and the front of the ridge, the downward airflow created a favorable condition for N. lugens to land in the study area. In conclusion, the northward migration of N. lugens was influenced by a low-frequency atmospheric circulation based on the analysis of dynamics. This study was the first research connecting atmospheric low-frequency oscillation to insect migration.
