<strong>Introduction:</strong> Stroke is the main cause of adult disability and the second most leading cause of death worldwide. The number of deaths due to stroke is 5.54 million worldwide. Globally, 70%...<strong>Introduction:</strong> Stroke is the main cause of adult disability and the second most leading cause of death worldwide. The number of deaths due to stroke is 5.54 million worldwide. Globally, 70% of strokes and 87% of both stroke-related deaths and disability-adjusted life years occur in low and middle-income countries. <strong>Method:</strong> This was a prospective observational cross-sectional study conducted at Indoor, Outdoor, Stroke and Neuro-Intervention clinic of the Department of Neurology, Bangabandhu Sheikh Mujib Medical University Hospital (BSMMU), Dhaka, Bangladesh, from June-2019 to May-2020. A total of 220 ischemic stroke patients aged above 30 years confirmed by CT scan/MRI of brain. Data were collected with a pre-structured questionnaire from the patients, investigations reports and face-to-face interviews and analyzed using IBM SPSS software version 23.0. Proper consent was taken from the participants. The collected data were ANNOVA tests and association within the risk factors and the patterns of subtypes of ischemic stroke where P < 0.05 considered significant. <strong>Results:</strong> Among the 220 stroke patients, large-artery atherosclerosis (LAA), cardio-embolism (CE), small-vessel occlusion (SVO, stroke of other determined etiology (SODE) and stroke of undetermined etiology (SUDE) were being observed 84 (38.18%), 14 (6.36%), 63 (28.64%), 12 (5.45%) and 47 (18.18%). Eighty-Six (39.09%) prevalence of subtypes was found in rural areas whereas 134 (60.91%) were in urban areas. The significant risk factors are associated with the prevalence of various subtypes (p < 0.05). <strong>Conclusion:</strong> This study prevails the people of Bangladesh are vulnerable to various subtypes of ischemic stroke. The higher prevalence of large-artery atherosclerosis (LAA) in our patients suggests the presence of uncontrolled hypertension, diabetes mellitus, smoking habit and dyslipidemia.展开更多
目的调查青年卒中患者各危险因素及影像学检查情况,探讨青年卒中住院患者的危险因素及病因学特点。方法回顾性收集首都医科大学附属北京安贞医院神经内科2002年1月至2010年12月期间连续登记住院的青年卒中(18~44岁)患者的病历资料入组...目的调查青年卒中患者各危险因素及影像学检查情况,探讨青年卒中住院患者的危险因素及病因学特点。方法回顾性收集首都医科大学附属北京安贞医院神经内科2002年1月至2010年12月期间连续登记住院的青年卒中(18~44岁)患者的病历资料入组274例,并分层随机抽取同期住院的中老年卒中(45岁及以上)患者入组300例,分析其众多危险因素及病因学构成特点。结果①青年卒中组中,缺血性卒中229例(83.58%),男性211例(77.01%);年龄在40~44岁的患者160例(58.39%);②青年卒中组,合并高血压179例(65.33%)、吸烟162例(59.12%)、饮酒123例(44.89%)、高同型半胱氨酸血症100例(39.84%)、肥胖86例(31.39%),与中老年卒中组对比,差异有显著性(P<0.05);合并高脂血症156例(56.93%),两组间差异无显著性(P>0.05);③缺血性卒中经TOAST(Trial of Org 10 172 in Acute Stroke Treatment)病因学分型,青年组大动脉粥样硬化性卒中100例(44.25%)和小动脉闭塞性卒中66例(29.20%),与中老年组对比,差异有显著性(P<0.05);④青年组颅内外血管情况优于中老年组,主要动脉无异常的患者比率(26.55%)高于中老年组(15.79%),轻、中度和重度狭窄率(46.02%和7.96%)低于中老年组(50.20%和17.81%),两组间差异有显著性(P<0.05)。结论①青年卒中以缺血性卒中、男性为主,其中40~44岁的患者占1/2以上;②青年卒中主要的危险因素依次是高血压、吸烟、高脂血症、饮酒、高同型半胱氨酸血症、肥胖,其中高血压、吸烟、高脂血症、高同型半胱氨酸血症的百分率随年份的增长有逐渐增高趋势;③青年缺血性卒中主要的病因是大动脉粥样硬化性卒中、小动脉闭塞性卒中,其他病因多样化;④青年卒中患者的颅内外血管情况优于中老年卒中患者。展开更多
文摘<strong>Introduction:</strong> Stroke is the main cause of adult disability and the second most leading cause of death worldwide. The number of deaths due to stroke is 5.54 million worldwide. Globally, 70% of strokes and 87% of both stroke-related deaths and disability-adjusted life years occur in low and middle-income countries. <strong>Method:</strong> This was a prospective observational cross-sectional study conducted at Indoor, Outdoor, Stroke and Neuro-Intervention clinic of the Department of Neurology, Bangabandhu Sheikh Mujib Medical University Hospital (BSMMU), Dhaka, Bangladesh, from June-2019 to May-2020. A total of 220 ischemic stroke patients aged above 30 years confirmed by CT scan/MRI of brain. Data were collected with a pre-structured questionnaire from the patients, investigations reports and face-to-face interviews and analyzed using IBM SPSS software version 23.0. Proper consent was taken from the participants. The collected data were ANNOVA tests and association within the risk factors and the patterns of subtypes of ischemic stroke where P < 0.05 considered significant. <strong>Results:</strong> Among the 220 stroke patients, large-artery atherosclerosis (LAA), cardio-embolism (CE), small-vessel occlusion (SVO, stroke of other determined etiology (SODE) and stroke of undetermined etiology (SUDE) were being observed 84 (38.18%), 14 (6.36%), 63 (28.64%), 12 (5.45%) and 47 (18.18%). Eighty-Six (39.09%) prevalence of subtypes was found in rural areas whereas 134 (60.91%) were in urban areas. The significant risk factors are associated with the prevalence of various subtypes (p < 0.05). <strong>Conclusion:</strong> This study prevails the people of Bangladesh are vulnerable to various subtypes of ischemic stroke. The higher prevalence of large-artery atherosclerosis (LAA) in our patients suggests the presence of uncontrolled hypertension, diabetes mellitus, smoking habit and dyslipidemia.
文摘目的调查青年卒中患者各危险因素及影像学检查情况,探讨青年卒中住院患者的危险因素及病因学特点。方法回顾性收集首都医科大学附属北京安贞医院神经内科2002年1月至2010年12月期间连续登记住院的青年卒中(18~44岁)患者的病历资料入组274例,并分层随机抽取同期住院的中老年卒中(45岁及以上)患者入组300例,分析其众多危险因素及病因学构成特点。结果①青年卒中组中,缺血性卒中229例(83.58%),男性211例(77.01%);年龄在40~44岁的患者160例(58.39%);②青年卒中组,合并高血压179例(65.33%)、吸烟162例(59.12%)、饮酒123例(44.89%)、高同型半胱氨酸血症100例(39.84%)、肥胖86例(31.39%),与中老年卒中组对比,差异有显著性(P<0.05);合并高脂血症156例(56.93%),两组间差异无显著性(P>0.05);③缺血性卒中经TOAST(Trial of Org 10 172 in Acute Stroke Treatment)病因学分型,青年组大动脉粥样硬化性卒中100例(44.25%)和小动脉闭塞性卒中66例(29.20%),与中老年组对比,差异有显著性(P<0.05);④青年组颅内外血管情况优于中老年组,主要动脉无异常的患者比率(26.55%)高于中老年组(15.79%),轻、中度和重度狭窄率(46.02%和7.96%)低于中老年组(50.20%和17.81%),两组间差异有显著性(P<0.05)。结论①青年卒中以缺血性卒中、男性为主,其中40~44岁的患者占1/2以上;②青年卒中主要的危险因素依次是高血压、吸烟、高脂血症、饮酒、高同型半胱氨酸血症、肥胖,其中高血压、吸烟、高脂血症、高同型半胱氨酸血症的百分率随年份的增长有逐渐增高趋势;③青年缺血性卒中主要的病因是大动脉粥样硬化性卒中、小动脉闭塞性卒中,其他病因多样化;④青年卒中患者的颅内外血管情况优于中老年卒中患者。