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Correlation between psychological traits and the use of smart medical services in young and middle-aged adults: An observational study
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作者 Hu Zhang Yan Liu Rui Gu 《World Journal of Psychiatry》 SCIE 2024年第8期1224-1232,共9页
BACKGROUND Psychological problems affect economic development.However,there is a huge gap between mental health service resources and mental health service needs.Existing mental health service technology and platforms... BACKGROUND Psychological problems affect economic development.However,there is a huge gap between mental health service resources and mental health service needs.Existing mental health service technology and platforms cannot meet all the diverse mental health needs of people.Smart medicine is a new medical system based online that can effectively improve the quality and efficiency of medical services and make mental health services accessible.AIM To explore the level of intelligent medical use among young and middle-aged people and its correlation with psychological factors.METHODS Convenience sampling was used to select 200 young and middle-aged patients with medical experience at the Third People's Hospital of Chengdu between January 2022 and January 2023 as the research subjects.The general condition Questionnaire,Eysenck Personality Questionnaire,Symptom Checklist-90,General Health Questionnaire,and Smart Medical Service Use Intention Questionnaire were used to collect data.Pearson’s correlation was used to analyze the correlation between the participants’willingness to use smart medical services and their personality characteristics,psychological symptoms,and mental health.RESULTS The results revealed that the mental health of young and middle-aged people was poor,and some had psycho-logical problems such as anxiety,depression,and physical discomfort.Familiarity,acceptance,and usage of smart healthcare in this population are at a medium level,and these levels correlate with psychological characteristics.Acceptance was positively correlated with E,and negatively correlated with P,anxiety,fear,anxiety/insomnia,and social dysfunction.The degree of use was negatively correlated with P,obsessive-compulsive symptoms,depression,anxiety,hostility,paranoia,and somatic symptoms.CONCLUSION The familiarity,acceptance,and usage of smart medical services among the middle-aged and young groups are related to various psychological characteristics. 展开更多
关键词 young and middle-aged people Smart healthcare Willingness to serve Psychological characteristics Questionnaire survey RELEVANCE
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Study on the association of multimorbidity with sleep and diet in young and middle-aged adults in Chongqing region,China
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作者 Mei Zhao Hai-Hang Qin +3 位作者 Rong Sun Jing Zhang Xue-Qin Yan Wei-Wei Liu 《Medical Data Mining》 2024年第4期50-55,共6页
Background:The prevalence of multimorbidity is increasing,with a notable shift towards younger age groups.Methods:Convenience sampling was employed to select 15,988 young and middle-aged adults in Chongqing as the stu... Background:The prevalence of multimorbidity is increasing,with a notable shift towards younger age groups.Methods:Convenience sampling was employed to select 15,988 young and middle-aged adults in Chongqing as the study population.The Apriori algorithm was used to identify the multimorbidity patterns within this population,while an unordered binary logistic regression model was applied to assess the association between sleep,diet and the risk of multimorbidity.Results:The study population had an average age of 39.2±10.1 years.Apriori association rules revealed that the most prevalent binary chronic disease multimorbidity pattern was dyslipidaemia+hypertension(14.78%),while the most common ternary chronic disease multimorbidity pattern was diabetes+dyslipidaemia+hypertension(9.66%).The logistic regression analysis revealed that a lower rating of sleep quality was associated with an elevated risk of multimorbidity(odds ratio(OR)=1.17,95%confidence interval(CI):1.01,1.36).Individuals who adhere to a meat-based diet(OR=1.45,95%CI:1.25,1.68)and those with elevated salt intake(OR=1.22,95%CI:1.01,1.47)were also observed to have an increased risk of multimorbidity.Additionally,a greater likelihood of multimorbidity was observed among those following a spicy diet(OR=1.3,95%CI:1.11,1.52)and consuming more oil(OR=1.16,95%CI:1.01,1.33).Conclusion:A poor sleep quality and a dietary preference for meat-based,salt,spicy and oils were found to be associated with an increased risk of multimorbidity progression among young and middle-aged populations.It is recommended that young and middle-aged adults should pay attention not only to sleep duration but also to sleep quality and improve dietary habits to reduce the likelihood of multimorbidity. 展开更多
关键词 young and middle-aged adults SLEEP DIET MULTIMORBIDITY
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The Relationship between Mental Health Literacy and Subjective Well-Being of Young and Middle-Aged Residents: Perceived the Mediating Role of Social Support and Its Urban-Rural Differences 被引量:2
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作者 Zhen Zhang Suyan Chen +4 位作者 Xiaoxuan Wang Jun Liu Yilin Zhang Yongxia Mei Zhenxiang Zhang 《International Journal of Mental Health Promotion》 2023年第4期471-483,共13页
This study investigates mental health literacy among young and middle-aged urban and rural residents and the differences in mental health literacy,perceived social support and subjective well-being.From January to Feb... This study investigates mental health literacy among young and middle-aged urban and rural residents and the differences in mental health literacy,perceived social support and subjective well-being.From January to February 2022,620 participants(320 rural and 300 urban residents)from three provinces of China were selected by con-venience sampling.A general data questionnaire,mental health literacy scale,perceived social support scale and subjective well-being scale were administered.The mental health literacy scores of urban residents were 3.34±0.57 and those of rural residents were 2.73±0.79.The results of multiple regression analysis showed that the mental health literacy scores of rural residents were more significant than those of urban residents in terms of sex and age,while urban residents’mental health literacy scores were more significant than those of rural resi-dents in terms of monthly income.Mental health literacy,perceived social support and subjective well-being of young and middle-aged urban and rural residents were all positively correlated(P<0.01).While the level of mental health literacy is better among urban residents than rural residents,perceived social support plays a partial mediating role between mental health literacy and subjective well-being of both urban and rural residents,and should be the focus of researchers seeking to improve the level of well-being of residents. 展开更多
关键词 young and middle-aged people mental health literacy perceived social support subjective well-being mediating role
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Effect of Age and Sex on Stroke Mortality of Young and Middle-aged Adults in China,2002–2019,and Predictions to 2030
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作者 ZHAI Yi SI Xiang +1 位作者 WANG Wen Zhi ZHAO Wen Hua 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2023年第4期305-312,共8页
Objective This study aimed to examine the trends in stroke mortality among young and middle-aged adults in China.Methods Data were obtained from the China national vital registration system.Significant changes in mort... Objective This study aimed to examine the trends in stroke mortality among young and middle-aged adults in China.Methods Data were obtained from the China national vital registration system.Significant changes in mortality were assessed by Joinpoint regression.Age-period-cohort analysis was used to explain the reasons for the changes.Future mortality and counts were predicted by the Bayesian age-period-cohort model.Results Between 2002 and 2019,a total of 6,253,951 stroke mortality in young and middle-aged adults were recorded.The age-adjusted mortality rates(AAMRs)of women showed a downward trend.The annual percent changes(APC)were-3.5%(-5.2%,-1.7%)for urban women and-2.8%(-3.7%,-1.9%)for rural women.By contrast,the AAMRs per 100,000 for rural men aged 25–44 years continued to rise from 9.40 to 15.46.The AAMRS for urban men aged 25–44 years and urban and rural men aged 45–64years did not change significantly.Between 2020 and 2030,the projected stroke deaths are 1,423,584 in men and 401,712 in women.Conclusion Significant sex and age disparities in the trends of stroke mortality among young and middle-aged adults were identified in China.Targeted health policy measures are needed to address the burden of stroke in the young generation,especially for rural men,with a focus on the prevention and management of high risk factors. 展开更多
关键词 STROKE MORTALITY young and middle-aged Joinpoint regression Age-period-cohort analysis
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Influencing factors of fatigue in young and middle-aged patients with coronary heart disease:a cross-sectional study
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作者 Lu Yu Yao-Yao Hu +3 位作者 Jing Zhang Fang-Ying Mao Qing Wu Lin Liu 《Life Research》 2023年第2期20-29,共10页
Objective:To examine the present state of fatigue in young and middle-aged patients with coronary heart disease(CHD)and to identify the elements that may be affecting it.Methods:From December 2020 to June 2021,240 you... Objective:To examine the present state of fatigue in young and middle-aged patients with coronary heart disease(CHD)and to identify the elements that may be affecting it.Methods:From December 2020 to June 2021,240 young and middle-aged patients with CHD who were being treated in the cardiology department of a tertiary care hospital in Suzhou were chosen using a convenience sampling method in order to gather data on the patients’sociodemographic status,fatigue,social support,and stress.Results:Of the 240 disseminated questionnaires,220 valid responses were returned,resulting in an effective recovery rate of 91.67%.The frequency of exhaustion was 51.8%,and the fatigue score was(5.27±2.77).The stress score was(11.15±3.36),while the overall social support score was(39.13±4.72).Binary logistic regression analysis indicated that age,exercise,staying up late,stress,social support,high-sensitivity troponin T,high-density lipoprotein,and ejection fraction were independent risk factors for fatigue in young and middle-aged patients with CHD(P<0.05).Conclusions:Fatigue is more prevalent in young and middle-aged patients with CHD.Clinical nurses can create a unique management plan for patients based on their lifestyle and behavioral patterns,stress levels,social support,and clinical signs to reduce fatigue. 展开更多
关键词 young and middle-aged adults coronary heart disease FATIGUE influencing factors symptom experience model
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Association of fatigue with short-term prognosis in young and middle-aged patients with coronary heart disease
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作者 Fang-Ying Mao Lu Yu +1 位作者 Qing Wu Jing Zhang 《Psychosomatic Medicine Research》 2023年第2期1-8,共8页
Background:To investigate the effect of fatigue on the short-term prognosis of young and middle-aged patients with coronary heart disease(CHD).Methods:A cross-sectional,observational survey was distributed at a tertia... Background:To investigate the effect of fatigue on the short-term prognosis of young and middle-aged patients with coronary heart disease(CHD).Methods:A cross-sectional,observational survey was distributed at a tertiary hospital in Suzhou,China.Patients were assessed for fatigue and their prognosis was assessed at 3 and 6 months after discharge.General Information Questionnaire,Fatigue Scale and Seattle Angina Questionnaire(SAQ)were used for the survey.The Cox proportional hazard model was used to analyze the impact of fatigue on the occurrence of major adverse cardiac events(MACEs)at 3 and 6 months after discharge.Multiple linear regression models were used to analyze the effect of fatigue on health-related quality of life(HRQoL)at 3 and 6 months after discharge.Results:199 patients were followed up with in the end.43 patients(21.6%)with MACE three months after discharge had a total SAQ score of(399.76±39.61).The overall SAQ score was(425.14±22.66)and 52 patients(26.1%)experienced MACE six months after discharge.Fatigue was identified as a risk factor for MACE 6 months after discharge by the Cox proportional hazard model(HR=2.939,95%CI:0.177~0.655,P=0.001)and as an independent risk factor for quality of life 3 and 6 months after discharge by multiple linear regression(P<0.001).Conclusions:In individuals who are young or middle-aged and have coronary heart disease,fatigue is a risk factor for the short-term prognosis.It is advised that clinical professionals prioritize patient fatigue assessment and improve management of fatigue symptoms. 展开更多
关键词 coronary heart disease FATIGUE major adverse cardiovascular events quality of life young and middle-aged
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Factors associated with financial support in old age for young and middle-aged rural residents in China
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作者 Suyan Shen Fang Li John Kipkorir Tanui 《Chinese Journal of Population,Resources and Environment》 2015年第2期169-176,共8页
This study examined the factors associated with financial support in old age from three primary mechanisms-personal savings,family support,and social insurance-to explore the implications for the future development of... This study examined the factors associated with financial support in old age from three primary mechanisms-personal savings,family support,and social insurance-to explore the implications for the future development of China's rural social welfare system.Cross-sectional surveys of 1392 young and middle-aged rural residents were conducted in July and August2012.The results showed that while social insurance was increasingly acceptable,personal savings and family support still had fundamental value.Combining the three mechanisms,the rural old-age welfare system presented nontraditional features.China's new rural endowment insurance is discussed as a means to address the need for financial support among the rural aging population. 展开更多
关键词 OLD-AGE financial SUPPORT young and middle-aged rural RESIDENTS personal SAVINGS family SUPPORT social INSURANCE
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Psychosocial Adaptation Level and Work Participation Rate of Young and Middle-aged Patients with Coronary Heart Disease after PCI
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作者 Hongyun ZHENG Yan ZHAN Li ZHANG 《Medicinal Plant》 CAS 2022年第3期68-70,74,共4页
[Objectives]The research aimed to understand the psychosocial adjustment to illness of young and middle-aged patients with coronary heart disease after PCI and their participation situation in work.[Methods]210 young ... [Objectives]The research aimed to understand the psychosocial adjustment to illness of young and middle-aged patients with coronary heart disease after PCI and their participation situation in work.[Methods]210 young and middle-aged patients aged 18-59 years with coronary heart disease treated by PCI in a tertiary hospital of Suzhou from July of 2020 to November of 2022 were selected,and general information of patients in three days after operation was registered.Self-report psychosocial adjustment to illness scale(PAIS-SR)was used to investigate the psychosocial adjustment to illness of patients in 1,3 and 6 months after operation and the participation rate of work.[Results]The psychosocial adjustment to illness of young and middle-aged patients with coronary heart disease after PCI was different in gender,age,education level,marital status,hypertension,diabetes,postoperative cardiac color Doppler ultrasound results(left ventricular ejection fraction)and the number of stents(P<0.05).[Conclusions]The psychosocial adjustment to illness of young and middle-aged patients with coronary heart disease after PCI needs to be improved.The psychosocial adjustment to illness of men is higher than that of women.The older the age is,the lower the psychosocial adjustment to illness is.The psychosocial adjustment to illness of patients with high educational background is higher than those with low educational background,while the psychosocial adjustment to illness of married people is higher than unmarried people.The psychosocial adjustment to illness of patients with hypertension and/or diabetes is lower. 展开更多
关键词 young and middle-aged Coronary heart disease PCI PSYCHOLOGY
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Correlation of blood uric acid level with the degree of anxiety as well as the neurotransmitter and cytokine secretion in young and middle-aged patients with anxiety disorder
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作者 Xiao-Bei Liu Xiao-Jun Hou 《Journal of Hainan Medical University》 2019年第2期62-65,共4页
Objective:To study the correlation of blood uric acid level with the degree of anxiety as well as the neurotransmitter and cytokine secretion in young and middle-aged patients with anxiety disorder.Methods: The young ... Objective:To study the correlation of blood uric acid level with the degree of anxiety as well as the neurotransmitter and cytokine secretion in young and middle-aged patients with anxiety disorder.Methods: The young and middle-aged patients diagnosed with generalized anxiety disorder in our hospital between March 2015 and February 2018 were selected as the anxiety group, and the healthy subjects receiving physical examination during the same period were selected as the control group. Peripheral blood was collected to determine the contents of uric acid, neurotransmitters and cytokines, and Hamilton Anxiety Scale (HAMA) was adopted to judge the degree of anxiety.Results: The blood uric acid level of anxiety group was obviously higher than that of control group and the higher the HAMA scores, the more significant the rising of blood uric acid levels;serum 5-hydroxytryptamine (5-HT), norepinephrine (NE), dopamine (DA), interleukin-1α (IL-1α), IL-17 and interferon-γ (IFN-γ) contents of anxiety group were significantly higher than those of control group whereas neuropeptide Y (NPY), IL-4 and transforming growth factor-β (TGF-β) contents were significantly lower than those of control group;blood uric acid level of the anxiety group was positively correlated with 5-HT, NE, DA, IL-1 , IL-17 and IFN-γ contents, and negatively correlated with NPY, IL-4 and TGF-β contents.Conclusion: The rise of blood uric acid level in young and middle-aged patients with anxiety disorder is related to the aggravation of anxiety degree as well as the abnormal secretion of neurotransmitters and cytokines. 展开更多
关键词 ANXIETY disorder in the young and middle-aged BLOOD uric acid NEUROTRANSMITTER CYTOKINE
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Experience of Treating Hypertension from Liver and Spleen Among Middle-Aged and Young Patients:A Summary
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作者 Caiying Li 《Journal of Clinical and Nursing Research》 2022年第2期25-29,共5页
Qi deficiency of the spleen and stomach,transportation,phlegm and dampness generate endogenous and turbid phlegm that violates the position of yang clearance.As a result,dizziness cis resulted.The author believes that... Qi deficiency of the spleen and stomach,transportation,phlegm and dampness generate endogenous and turbid phlegm that violates the position of yang clearance.As a result,dizziness cis resulted.The author believes that the incidence of middle-aged and young patients with hypertension is mostly related to the dysfunction of liver and spleen.Liver depression and qi stagnation is the beginning of the onset;spleen deficiency and dyskinesia is the norm of the onset;and liver and spleen imbalance is the origin of the onset.It is advocated that regulating the liver and spleen to restore the rise and fall,harmonizing qi and blood and preventing lesions are the main treatment methods for the treatment of middle-aged and young people’s hypertension,which is conducive to the development of more clinical diagnosis and treatment ideas for hypertension amomg middle-aged and young people. 展开更多
关键词 HYPERTENSION young and middle-aged Liver and spleen Clinical experience
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321例青年初治肺结核患者社会疏离感现状及影响因素研究 被引量:3
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作者 吴茜 蒋宇 +3 位作者 金梦杰 范恩 施莉 王梅新 《护理学报》 2024年第4期65-69,共5页
目的 调查321例青年初治肺结核患者社会疏离感现状,并分析其影响因素。方法 采用便利抽样法,选取2022年1月—2023年4月新疆喀什及和田地区结核病定点医院登记的321例青年初治肺结核患者作为研究对象。采用一般资料调查表、一般疏离感量... 目的 调查321例青年初治肺结核患者社会疏离感现状,并分析其影响因素。方法 采用便利抽样法,选取2022年1月—2023年4月新疆喀什及和田地区结核病定点医院登记的321例青年初治肺结核患者作为研究对象。采用一般资料调查表、一般疏离感量表、结核病病耻感量表、简易版疾病感知问卷进行调查。采用多重线性回归分析青年初治肺结核患者社会疏离感影响因素。结果 本组青年初治肺结核患者社会疏离感总分为[41.00(35.00,44.00)]分。多重线性回归分析结果显示,性别、文化程度、家庭人均月收入、疾病感知、病耻感是青年初治肺结核患者社会疏离感的影响因素(P<0.05),共解释总变异的39.9%。结论 321例青年初治肺结核患者社会疏离感处于中等水平。医务人员应重点关注女性、文化程度低、家庭经济收入低、疾病感知水平高、病耻感强烈的患者,整合社会资源,调动各方社会支持,关注心理状态,及时给予其心理疏导,普及结核病相关知识,纠正其负性认知。 展开更多
关键词 青年 肺结核 社会疏离感 疾病感知 病耻感
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医患视角下初治中青年肺结核患者延迟重返工作成因的质性研究
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作者 钟年好 郑镇泳 +2 位作者 吴少玲 胡亚南 谭益冰 《护理学杂志》 CSCD 北大核心 2024年第12期90-93,共4页
目的深入了解中青年肺结核患者重返工作的成因,为制定中青年肺结核患者重返工作的支持性干预策略提供参考。方法采取现象学研究方法,于2023年5-7月在广州市某专科医院,选取10名结核科医护人员和16例中青年肺结核患者进行半结构式访谈,采... 目的深入了解中青年肺结核患者重返工作的成因,为制定中青年肺结核患者重返工作的支持性干预策略提供参考。方法采取现象学研究方法,于2023年5-7月在广州市某专科医院,选取10名结核科医护人员和16例中青年肺结核患者进行半结构式访谈,采用Colaizzi七步分析法分析访谈资料。结果分析得出3个主题及7个亚主题:污名化伤害(强烈的病耻感、工作被区别对待、来自同事的疏离感)、疾病相关恐惧(持续的身体不适、复发恐惧心理)、专科宣教不足(缺乏专业建议、缺乏专业科普)。结论中青年肺结核患者普遍存在延迟重返工作现象,应通过心理干预和多元化支持,帮助中青年肺结核患者在合适的阶段重返工作。 展开更多
关键词 中青年 肺结核 重返工作 职业康复 社会融入 延迟返岗 医患视角 质性研究
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青年肺结核病人疾病获益感现状及影响因素
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作者 李新月 唐苏姚 +3 位作者 王梦梦 潘舒雯 王丹 沙莉 《循证护理》 2024年第10期1837-1843,共7页
目的:了解青年肺结核病人疾病获益感现状,并分析其影响因素。方法:选取2022年10月—2023年3月于南京市某三级结核病定点治疗医院结核科治疗的263例青年肺结核病人作为研究对象,应用一般资料调查表、疾病获益感量表、伯克利情绪表达量表... 目的:了解青年肺结核病人疾病获益感现状,并分析其影响因素。方法:选取2022年10月—2023年3月于南京市某三级结核病定点治疗医院结核科治疗的263例青年肺结核病人作为研究对象,应用一般资料调查表、疾病获益感量表、伯克利情绪表达量表、领悟社会支持评定量表、医学应对方式问卷进行调查。结果:青年肺结核病人疾病获益感得分为(65.05±14.16)分。多重线性回归分析结果显示,年龄、患病时长、自我表露、领悟社会支持、医学应对方式是青年肺结核病人疾病获益感的主要影响因素,可解释总变异的51.1%。结论:青年肺结核病人疾病获益感处于中等水平,临床医护人员应重视青年肺结核病人的积极感知,鼓励青年病人表达患病体验,引导青年病人充分利用外界支持积极应对疾病,以提高疾病获益感水平。 展开更多
关键词 肺结核 青年病人 疾病获益感 自我表露 领悟社会支持 医学应对方式
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ApoA1和AFP联合检测对中青年肺结核的临床应用价值 被引量:1
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作者 崔丹 董跃明 +2 位作者 王心静 孙立姝 孟祥红 《国际检验医学杂志》 CAS 2023年第24期2950-2953,共4页
目的探讨载脂蛋白A1(ApoA1)和甲胎蛋白(AFP)联合检测对中青年肺结核的临床应用价值。方法选取该院2020年12月至2021年12月收治的中青年肺结核患者82例作为观察组,同期于该院进行健康体检的体检健康者85例作为对照组。比较两组临床、血... 目的探讨载脂蛋白A1(ApoA1)和甲胎蛋白(AFP)联合检测对中青年肺结核的临床应用价值。方法选取该院2020年12月至2021年12月收治的中青年肺结核患者82例作为观察组,同期于该院进行健康体检的体检健康者85例作为对照组。比较两组临床、血脂、炎症及铁代谢相关指标,采用多因素Logistic回归分析中青年肺结核的影响因素,采用受试者工作特征(ROC)曲线下面积(AUC)评估ApoA1、AFP及二者联合在诊断中青年肺结核中的应用价值。结果观察组直接胆红素、肌酐、AFP、超敏C反应蛋白水平高于对照组(P<0.05),甘油三酯、总胆固醇、高密度脂蛋白胆固醇及ApoA1水平明显低于对照组(P<0.05)。多因素Logistic回归分析显示,ApoA1是中青年肺结核的独立保护因素(OR=0.119,95%CI 0.019~0.754,P=0.024),AFP是中青年肺结核的独立危险因素(OR=1.554,95%CI 1.138~2.122,P=0.006)。ApoA1、AFP及二者联合预测中青年肺结核的AUC分别为0.644(P=0.006)、0.262(P<0.001)、0.678(P=0.001)。结论中青年肺结核患者ApoA1水平较低,是中青年肺结核的独立保护因素,AFP水平较高,是中青年肺结核的独立危险因素,二者联合检测在预测中青年肺结核方面具有良好价值。 展开更多
关键词 中青年肺结核 载脂蛋白A1 甲胎蛋白
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Sun Fengyan, a model for young and middle-aged professionals
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作者 ZHANG SHENFEN 《Women of China》 1999年第9期4-5,共2页
APOPLEXY is generally acknowledgedin medical circles as a forceful killer.It resultsin ischemic damage of the nerve cells(a lackof blood supply).some of which die andothers of which survive.Can we stop thedeath ot the... APOPLEXY is generally acknowledgedin medical circles as a forceful killer.It resultsin ischemic damage of the nerve cells(a lackof blood supply).some of which die andothers of which survive.Can we stop thedeath ot these cells by medical means,or atleast raise the survival rate and rehabilitatethem?That is what Professor Sun Fengyanwith the Shanghai Medical SciencesUniversity is working on. Sun Fengyan was conferred a Doctor ofnerve pharmacologia in 1987 and three 展开更多
关键词 Sun Fengyan a model for young and middle-aged professionals
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成年人肺结核患者T淋巴细胞亚群、自然杀伤细胞及免疫球蛋白的检测与分析 被引量:18
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作者 周世明 贾杰 杨建国 《中国热带医学》 CAS 2003年第6期767-769,共3页
目的 探讨老年人与青壮年人肺结核患者的免疫功能的特点 ,以指导临床治疗。 方法  93例活动性肺结核病人 ,按年龄分为青壮年组和老年组。应用流式细胞术检测 3 3例老年人肺结核、60例青壮年肺结核的T淋巴细胞亚群、自然杀伤细胞 ,比... 目的 探讨老年人与青壮年人肺结核患者的免疫功能的特点 ,以指导临床治疗。 方法  93例活动性肺结核病人 ,按年龄分为青壮年组和老年组。应用流式细胞术检测 3 3例老年人肺结核、60例青壮年肺结核的T淋巴细胞亚群、自然杀伤细胞 ,比浊法检测其血清免疫球蛋白 ,并检测 2 0例正常人T淋巴细胞亚群、自然杀伤细胞作为对照组。 结果 老年人肺结核与青壮年人比 ,CD4 、CD4 CD8比值下降与CD8、CD56 上升差异均有显著性 (P <0 0 1) ,与对照组比 ,CD8与CD56 上升、CD4 CD8比值下降差异均有显著性 (P <0 0 1) ,血清IgG、IgM、IgA水平改变差异无显著性 (P>0 0 5 )。 结论 老年人肺结核细胞免疫功能低下 。 展开更多
关键词 成年人 肺结核 T淋巴细胞亚群 自然杀伤细胞 免疫球蛋白 检测 分析
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全程护理干预对中青年肺结核患者遵医行为和生活质量影响的研究 被引量:25
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作者 杨绍平 张素芬 +2 位作者 马兰 赖冬雪 胡恩梦 《西部医学》 2011年第12期2444-2446,共3页
目的探讨全程护理干预对中青年肺结核患者遵医行为和生活质量的影响。方法将84例中青年肺结核患者,随机分为实验组(42例)和对照组(42例),两组均给予对症支持治疗和常规护理,实验组在对症支持治疗和常规护理的基础上,给予全程护理干预。... 目的探讨全程护理干预对中青年肺结核患者遵医行为和生活质量的影响。方法将84例中青年肺结核患者,随机分为实验组(42例)和对照组(42例),两组均给予对症支持治疗和常规护理,实验组在对症支持治疗和常规护理的基础上,给予全程护理干预。两组患者在出院后1、3、6个月分别进行电话回访1次。在出院后6个月时分别进行遵医行为和生活质量问卷调查(SF-36),观察对比两组患者在遵医行为和生活质量评分有无差异性。结果两组患者在干预前后社会功能无明显差异性(P>0.05),实验组在遵医行为、角色功能、情绪功能、躯体功能以及总体生活质量等方面明显高于对照组,具有显著性差异(P<0.05)。结论对中青年肺结核患者进行完善的健康宣教、加强心理指导和出院指导等全程护理干预,从疾病、心理、社会等多个方面,进行多元化、预见性护理,能有效从心理和生理两方面促进患者的康复,提高患者的依从性和生活质量,对患者的治疗具有积极的促进作用,可取得较好的经济效益和社会效益。 展开更多
关键词 中青年肺结核 全程护理干预 遵医行为 生活质量
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1∶2个体匹配青年肺结核患者耐多药临床危险因素分析 被引量:4
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作者 刘慧梅 张瑞梅 +3 位作者 刘加彬 王春颖 席向宇 张礼营 《山西医科大学学报》 CAS 2016年第9期834-836,共3页
目的探讨青年肺结核患者耐多药临床危险因素,为耐多药早期预防提供临床依据。方法采用1∶2个体匹配病例对照研究,随机抽取2014-03~2016-03于徐州市传染病医院就诊的年龄≤40岁青年肺结核患者耐多药患者60例,同时筛选同期就诊单纯青年肺... 目的探讨青年肺结核患者耐多药临床危险因素,为耐多药早期预防提供临床依据。方法采用1∶2个体匹配病例对照研究,随机抽取2014-03~2016-03于徐州市传染病医院就诊的年龄≤40岁青年肺结核患者耐多药患者60例,同时筛选同期就诊单纯青年肺结核患者120例,收集两组患者临床资料,进行危险因素统计分析。结果单因素Logistic回归分析结果显示吸烟、空洞、病程、居住地、治疗中断、联合用药、高脂血症、支气管扩张、营养不良、药物不良反应、Hb A1c升高与青年肺结核患者耐多药发生相关(P〈0.05)。多因素分析结果显示存在空洞(OR=2.539,P=0.003)、存在营养不良(OR=2.751,P=0.013)、Hb A1c值升高(OR=3.254,P=0.003)是青年肺结核患者耐多药发生的危险因素,而居住地为城市(OR=0.299,P=0.022)是青年耐多药发生的保护因素。结论青年肺结核患者发生耐多药现象是由多种因素共同所致,根据不同的危险因素临床上应当采取不同有效预防措施。 展开更多
关键词 肺结核 青年 配对研究 危险因素
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先天性结核病的研究现状 被引量:8
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作者 陈桂华 万朝敏 《临床儿科杂志》 CAS CSCD 北大核心 2007年第2期151-153,共3页
目前,结核病仍然是引发死亡的主要原因之一。先天性结核病与其他类型的结核病有不同的流行病学特点,并且在诊断治疗措施方面也有其特殊性。由于目前多数文献报道仅关注于成人结核病和年龄较长儿童结核病,故有必要对先天性结核病的一些... 目前,结核病仍然是引发死亡的主要原因之一。先天性结核病与其他类型的结核病有不同的流行病学特点,并且在诊断治疗措施方面也有其特殊性。由于目前多数文献报道仅关注于成人结核病和年龄较长儿童结核病,故有必要对先天性结核病的一些研究作一综述。 展开更多
关键词 结核病 先天性 婴幼儿 垂直传播
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莫西沙星治疗中青年耐多药肺结核的疗效 被引量:10
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作者 邓俊亮 华美香 陈键腾 《临床肺科杂志》 2016年第12期2200-2202,共3页
目的观察莫西沙星与左氧氟沙星辅助治疗中青年耐多药肺结核(MDR-PTB)的效果,并评价两药的用药安全性。方法将106例中青年MDR-PTB患者随机分为两组,在常规抗结核药物治疗基础上,A组(n=53)给予莫西沙星,B组(n=53)给予左氧氟沙星,两组均持... 目的观察莫西沙星与左氧氟沙星辅助治疗中青年耐多药肺结核(MDR-PTB)的效果,并评价两药的用药安全性。方法将106例中青年MDR-PTB患者随机分为两组,在常规抗结核药物治疗基础上,A组(n=53)给予莫西沙星,B组(n=53)给予左氧氟沙星,两组均持续治疗12个月;比较两组的效果和不良反应。结果 A组的临床总有效率、痰菌转阴率、空洞关闭率均显著高于B组(P<0.05);两组的不良反应率无显著差异(P>0.05)。结论莫西沙星辅助治疗中青年耐多药肺结核的效果更好,不良反应率更低,更有效更安全。 展开更多
关键词 莫西沙星 青年耐多药肺结核 有效
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