This paper examines the educational implications of two curriculum initiatives in China that have produced curricular materials promoting education for sustainable development(ESD)in minority-populated ethnic autonomo...This paper examines the educational implications of two curriculum initiatives in China that have produced curricular materials promoting education for sustainable development(ESD)in minority-populated ethnic autonomous areas in China.The two curriculum projects present distinctive discourses,conceptions,models,frameworks and scopes of ESD in the country.Nonetheless,there is a likelihood that the actual implementation of the curriculum initiatives,especially the enactment of the curriculum materials produced,might be thwarted due to structural and systemic educational constraints,an anthropocentric approach to sustainable development,poor teacher support and teacher training,omissions of the affective learning components in curricular contents,as well as loopholes and weaknesses in the development of the curriculum materials themselves.展开更多
Background:The prevalence of hypertension is high among Chinese adults,thus,identifying non-hypertensive individuals at high risk for intervention will help to improve the efficiency of primary prevention strategies.M...Background:The prevalence of hypertension is high among Chinese adults,thus,identifying non-hypertensive individuals at high risk for intervention will help to improve the efficiency of primary prevention strategies.Methods:The cross-sectional data on 9699 participants aged 20 to 80 years were collected from the China National Health Survey in Gansu and Hebei provinces in 2016 to 2017,and they were nonrandomly split into the training set and validation set based on location.Multivariable logistic regression analysis was performed to develop the diagnostic prediction model,which was presented as a nomogram and a website with risk classification.Predictive performances of the model were evaluated using discrimination and calibration,and were further compared with a previously published model.Decision curve analysis was used to calculate the standardized net benefit for assessing the clinical usefulness of the model.Results:The Lasso regression analysis identified the significant predictors of hypertension in the training set,and a diagnostic model was developed using logistic regression.A nomogram with risk classification was constructed to visualize the model,and a website(https://chris-yu.shinyapps.io/hypertension_risk_prediction/)was developed to calculate the exact probabilities of hypertension.The model showed good discrimination and calibration,with the C-index of 0.789(95%confidence interval[CI]:0.768,0.810)through internal validation and 0.829(95%CI:0.816,0.842)through external validation.Decision curve analysis demonstrated that the model was clinically useful.The model had a higher area under receiver operating characteristic curves in training and validation sets compared with a previously published diagnostic model based on Northern China population.Conclusion:This study developed and validated a diagnostic model for hypertension prediction in Gansu Province.A nomogram and a website were developed to make the model conveniently used to facilitate the individualized prediction of hypertension in the general population of Han and Yugur.展开更多
文摘This paper examines the educational implications of two curriculum initiatives in China that have produced curricular materials promoting education for sustainable development(ESD)in minority-populated ethnic autonomous areas in China.The two curriculum projects present distinctive discourses,conceptions,models,frameworks and scopes of ESD in the country.Nonetheless,there is a likelihood that the actual implementation of the curriculum initiatives,especially the enactment of the curriculum materials produced,might be thwarted due to structural and systemic educational constraints,an anthropocentric approach to sustainable development,poor teacher support and teacher training,omissions of the affective learning components in curricular contents,as well as loopholes and weaknesses in the development of the curriculum materials themselves.
基金CAMS Innovation Fund for Medical Sciences(Nos.2020-I2M-2-009,2020-I2M-2-003)
文摘Background:The prevalence of hypertension is high among Chinese adults,thus,identifying non-hypertensive individuals at high risk for intervention will help to improve the efficiency of primary prevention strategies.Methods:The cross-sectional data on 9699 participants aged 20 to 80 years were collected from the China National Health Survey in Gansu and Hebei provinces in 2016 to 2017,and they were nonrandomly split into the training set and validation set based on location.Multivariable logistic regression analysis was performed to develop the diagnostic prediction model,which was presented as a nomogram and a website with risk classification.Predictive performances of the model were evaluated using discrimination and calibration,and were further compared with a previously published model.Decision curve analysis was used to calculate the standardized net benefit for assessing the clinical usefulness of the model.Results:The Lasso regression analysis identified the significant predictors of hypertension in the training set,and a diagnostic model was developed using logistic regression.A nomogram with risk classification was constructed to visualize the model,and a website(https://chris-yu.shinyapps.io/hypertension_risk_prediction/)was developed to calculate the exact probabilities of hypertension.The model showed good discrimination and calibration,with the C-index of 0.789(95%confidence interval[CI]:0.768,0.810)through internal validation and 0.829(95%CI:0.816,0.842)through external validation.Decision curve analysis demonstrated that the model was clinically useful.The model had a higher area under receiver operating characteristic curves in training and validation sets compared with a previously published diagnostic model based on Northern China population.Conclusion:This study developed and validated a diagnostic model for hypertension prediction in Gansu Province.A nomogram and a website were developed to make the model conveniently used to facilitate the individualized prediction of hypertension in the general population of Han and Yugur.