A comparison of the HPLC retention behaviour of the anti-progestins RU 38486 and ZK 98734 under reverse-phase conditions indicates some significant differences in their physico-chemical properties. A number of these p...A comparison of the HPLC retention behaviour of the anti-progestins RU 38486 and ZK 98734 under reverse-phase conditions indicates some significant differences in their physico-chemical properties. A number of these properties (e. g. basicities,solubilities and partition coefficients) are analysed and considered in connection with the differences in biological activity of these two anti-progestins.展开更多
文摘A comparison of the HPLC retention behaviour of the anti-progestins RU 38486 and ZK 98734 under reverse-phase conditions indicates some significant differences in their physico-chemical properties. A number of these properties (e. g. basicities,solubilities and partition coefficients) are analysed and considered in connection with the differences in biological activity of these two anti-progestins.