In this paper,the scientific research status of Zexie(Rhizoma Alismatis)was comprehensively expounded from the aspects of plant characteristics,source,chemical composition,pharmacological research and quality control ...In this paper,the scientific research status of Zexie(Rhizoma Alismatis)was comprehensively expounded from the aspects of plant characteristics,source,chemical composition,pharmacological research and quality control methods,etc.The market situation of Rhizoma Alismatis was systematically analyzed from historical and current perspectives;aiming at the problems of poor quality and irregular processing of Chinese medicinal herbs Rhizoma Alismatis,some ideas were put forward to improve the quality and market value of medicinal materials of Rhizoma Alismatis,so as to make the Chinese herbal medicine industry develop towards a healthy and efficient direction.展开更多
Objective: To investigate the effects of fluidized bed granulation with dextrin on moisture sorption and diffusion of Zexie Decoction granules.Methods: The particle characterization was studied by the particle size, s...Objective: To investigate the effects of fluidized bed granulation with dextrin on moisture sorption and diffusion of Zexie Decoction granules.Methods: The particle characterization was studied by the particle size, scanning electron microscopy(SEM), differential scanning calorimetry(DSC), and Fourier transform infrared(FTIR). The moisture sorption isotherm, equilibrium moisture content(EMC), and moisture diffusion coefficients were determined by using the saturated salt solution method.Results: The particle size increased from 6.04 μm(powder) to 1201.47 μm(granule). The glass transition temperature of dextrin, Zexie Decoction powder, and granule was 107.13 °C, 94.82 °C, and 126.25 °C. As the increase of temperature, the initial rate of moisture sorption become higher. Furthermore, the initial rate of moisture sorption of Zexie Decoction granules was lower than those of powders and dextrin. The EMC and moisture diffusion coefficients were reduced significantly after granulation(P < 0.01). Critical relative humidity and diffusion activation energy of granules were higher than powders.Conclusion: Results suggested that fluidized bed granulation with dextrin could reduce the hygroscopicity of the Zexie Decoction extract powders and inhibited moisture diffusion, which is mainly related to the microstructure reorganization by fluidized bed granulation and anti-plasticizing effects of dextrin.展开更多
基金Supported by the Project of Guangxi Natural Science Foundation(2017-GXNSFBA198239)Guangxi Major Special Project(Gui Ke Zhong 1598005-10)
文摘In this paper,the scientific research status of Zexie(Rhizoma Alismatis)was comprehensively expounded from the aspects of plant characteristics,source,chemical composition,pharmacological research and quality control methods,etc.The market situation of Rhizoma Alismatis was systematically analyzed from historical and current perspectives;aiming at the problems of poor quality and irregular processing of Chinese medicinal herbs Rhizoma Alismatis,some ideas were put forward to improve the quality and market value of medicinal materials of Rhizoma Alismatis,so as to make the Chinese herbal medicine industry develop towards a healthy and efficient direction.
基金financial support provided for this research by Tianjin Municipal Education Commission Research Project(Grant No.2017KJ134)
文摘Objective: To investigate the effects of fluidized bed granulation with dextrin on moisture sorption and diffusion of Zexie Decoction granules.Methods: The particle characterization was studied by the particle size, scanning electron microscopy(SEM), differential scanning calorimetry(DSC), and Fourier transform infrared(FTIR). The moisture sorption isotherm, equilibrium moisture content(EMC), and moisture diffusion coefficients were determined by using the saturated salt solution method.Results: The particle size increased from 6.04 μm(powder) to 1201.47 μm(granule). The glass transition temperature of dextrin, Zexie Decoction powder, and granule was 107.13 °C, 94.82 °C, and 126.25 °C. As the increase of temperature, the initial rate of moisture sorption become higher. Furthermore, the initial rate of moisture sorption of Zexie Decoction granules was lower than those of powders and dextrin. The EMC and moisture diffusion coefficients were reduced significantly after granulation(P < 0.01). Critical relative humidity and diffusion activation energy of granules were higher than powders.Conclusion: Results suggested that fluidized bed granulation with dextrin could reduce the hygroscopicity of the Zexie Decoction extract powders and inhibited moisture diffusion, which is mainly related to the microstructure reorganization by fluidized bed granulation and anti-plasticizing effects of dextrin.
