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Experimental Study on Effect of Compound Biejia Ruangan Prescription (复方鳖甲软肝方) on High Resolution Computerized Tomographic Images in Bleomycin Induced Pulmonary Fibrosis Rats 被引量:2
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作者 张东伟 王继峰 +2 位作者 牛建昭 高宝华 李贡宇 《Chinese Journal of Integrated Traditional and Western Medicine》 2003年第4期270-275,共6页
Objective: To study the therapeutic effect of Com pound Biejia Ruangan prescription (CBRP) on rat model with pulmonary fibrosis in duced by bleomycin. Methods: Fifty four male Sprague Dawley rats were rando mly divide... Objective: To study the therapeutic effect of Com pound Biejia Ruangan prescription (CBRP) on rat model with pulmonary fibrosis in duced by bleomycin. Methods: Fifty four male Sprague Dawley rats were rando mly divided into 6 groups (9 rats in each group). From the first day to the 28th day of the experiment, except to those in the sham model control group that were treated with normal saline, the same amount of bleomycin injection as the n ormal saline given to the control group was given through endotracheal instillat ion to all the rats in all the other groups. From the 29th day of the modeling, CBRP solution of different dosages was respectively injected into the rats in th e high, moderate and low CBRP dose group, while equal volume of normal saline w as given to those in the sham model control group and the model control group , and an equal volume of prednisone solution was given to rats in the prednisone group. On the 80th day, the high resolution computerized tomographic (HRCT) images were observed on an equal footing, and HRCT pathology was correlativel y studied. Results: Different HRCT pathological changes were shown in th e rats with pulmonary fibrosis, such as lung consolidation, thickening of interl obular septum and interlobular mesenchyma as well as lobular deformation, nodule shadow, abnormal brochiovascular tract, thickened pleura with irregular junctio n and polished glass like dense shadows. Honeycomb lung was observed in some cases. Pathological sections showed fibrotic proliferation of lung tissues and noticeable pulmonary interstitial fibrosis. CBRP could improve HRCT images of rats with pulmonary fibrosis, and lower fibrotic p roliferation of the lung tissue.Conclusion: CBRP plays its therapeutic role possibly through its effect on the structure of the lung in rats with pulmonary fibrosis. 展开更多
关键词 Compound Biejia Ruangan prescription rat s pulmonary fibrosis high resolution computerizd tomography
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Opioid Prescriptions in Women: Is the Data Accurate?
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作者 Keren Khromchenko Jonathan D. Baum 《Open Journal of Obstetrics and Gynecology》 CAS 2022年第9期934-940,共7页
Background: In 2012, U.S. health care providers wrote more than 259 million opioid prescriptions, which is twice as many as in 1998. Approximately 1 in 10 women report the use of opioids for pain management during pre... Background: In 2012, U.S. health care providers wrote more than 259 million opioid prescriptions, which is twice as many as in 1998. Approximately 1 in 10 women report the use of opioids for pain management during pregnancy. The Centers for Disease Control and Prevention (CDC) estimated that between 2008 and 2012, 39% of reproductive-aged women on Medicaid had filled a prescription for opioid medication each year, as did 28% of women with private insurance. The opioid epidemic extends to the state of New Jersey (NJ);however, limited data is available regarding opioid prescriptions among Medicaid and private insurance patients within the state. Objective: Evaluate opioid prescriptions filled in reproductive-aged women presenting in labor at a community teaching hospital in suburban New Jersey. Methods: We performed a retrospective cohort study using data obtained from patient records and the New Jersey Prescription Monitoring Program (NJPMP) database. We enrolled 200 patients that were admitted in labor between May 2015 and May 2016. Data was collected from reproductive-aged women during the one year preceding labor admission. We compared our findings to national data reported by the CDC using Chi-square analysis. Maternal demographic data were extracted from patient records and included age, insurance status (private insurance, Medicaid, and no insurance), race, and ethnicity. The primary outcome was opioid prescriptions filled. Results: Of the 200 women admitted in labor, 129 had private insurance, 63 had Medicaid, and 8 had no insurance. We found that 5.4% (7/129) of patients with private insurance, 4.8% (3/63) of patients with Medicaid, and 12.5% (1/8) of patients with no insurance filled opioid prescriptions. Overall, 5.5% (11/200) of women filled opioid prescriptions during the study period. Opioid prescriptions confirmed via NJPMP were significantly lower than rates reported by the CDC in Medicaid (4.8% vs. 41.4%, p-value 0.001) and private insurance (5.4% vs. 29.1%, p-value < 0.001) patients, respectively. Conclusion: Rates of opioid prescriptions filled were lower among our suburban cohort of women in New Jersey than national rates reported by the CDC. We did not confirm that patients with Medicaid filled more prescriptions than patients with private insurance. These discrepancies raise the question of whether a federal prescription monitoring program would better capture data than state-wide programs. Further research is needed to ensure that prescription monitoring programs are actually capturing accurate data. 展开更多
关键词 Centers for Disease Control and Prevention (CDC) MEDICAID New Jersey New Jersey prescription Monitoring Program (NJPMP) Opioid(s) prescription Private Insurance REPRODUCTIVE
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Understanding of He Hongfang’s Prescription(何鸿舫方)
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作者 Jin Quan 《Chinese Medicine and Culture》 2020年第1期47-49,共3页
He Hongfang(何鸿舫),a medical scholar in the Qing Dynasty,was the 24th descendant of He’s family in Jiangnan Region.He was famous in Shanghai during the reign of Tongzhi and Guangxu for his medicine and calligraphy.T... He Hongfang(何鸿舫),a medical scholar in the Qing Dynasty,was the 24th descendant of He’s family in Jiangnan Region.He was famous in Shanghai during the reign of Tongzhi and Guangxu for his medicine and calligraphy.This article introduces two frames of prescriptions of He Hongfang in the Shanghai Museum of Traditional Chinese Medicine for appreciation。 展开更多
关键词 He Hongfang’s prescription(何鸿舫方) He’s calligraphy shanghai Museum of Traditional Chinese Medicine
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A Study of Health Prescribing for Children with Tourette’s Disorders in Children’s Health Education Specialty Care Clinics
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作者 Wenping Yang Le Wang +2 位作者 Sha Wang Nannan Ma Li Mei 《Journal of Clinical and Nursing Research》 2024年第7期261-266,共6页
Objective:This study designs and implements the health prescription of children’s health education specialized nursing clinic based on the physical and mental characteristics of children with Tourette’s syndrome.Met... Objective:This study designs and implements the health prescription of children’s health education specialized nursing clinic based on the physical and mental characteristics of children with Tourette’s syndrome.Methods:Applying the evidence-based nursing model and nursing intervention theory based on the survey research by searching China Knowledge Network,Wanfang Database and Wipro Chinese Science and Technology Journal Database,the study collected the literature on the health prescription intervention research in children’s Tourette’s disorders health education in children’s health education of specialized nursing outpatient clinic for review and combined with the specialty characteristics to formulate“Children’s Tourette’s Disorder Health Education Prescription.”Results:Tourette’s syndrome in children is a common pediatric neurological disorder,mainly manifested as involuntary,rapid and repeated muscle twitching and vocal tics,which brings serious psychological pressure and life disturbance to the affected children.Conclusion:For children with Tourette’s syndrome,healthcare professionals should give enough care and understanding to the children and their parents,provide timely and effective health education to them,help them improve their bad behavioral habits,establish correct cognitive attitudes,enhance self-confidence,improve patient compliance,reduce the frequency of recurrence,reduce the incidence of complications and promote children’s physical and mental health development. 展开更多
关键词 Children’s health education specialty care clinic Childhood Tourette’s disorder Health prescription
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嗜蓝孢孔菌新种Fomitiporia yanbeiensis S. Guo&L. Zhou液体发酵培养条件研究 被引量:4
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作者 刘晓钢 周林 +4 位作者 徐莉娜 李艳婷 周伟 郭尚 侯雷平 《山西农业大学学报(自然科学版)》 CAS 北大核心 2018年第5期71-76,共6页
[目的]本研究是对Fomitiporia yanbeiensis S.Guo&L.Zhou液体发酵培养基的营养源和培养条件进行探索。[方法]以发酵培养液中的菌球生物量、菌丝生长速度和菌球萌发活力指数为主要指标,通过单因素试验和正交试验对发酵工艺的培养的... [目的]本研究是对Fomitiporia yanbeiensis S.Guo&L.Zhou液体发酵培养基的营养源和培养条件进行探索。[方法]以发酵培养液中的菌球生物量、菌丝生长速度和菌球萌发活力指数为主要指标,通过单因素试验和正交试验对发酵工艺的培养的温度、pH值、碳源、氮源、接种量进行优化筛选,研究最佳的发酵培养基配方,并对发酵菌丝体和子实体的功能性成分测定对比。[结果]液体发酵培养中最佳的发酵培养条件为:温度27℃、起始pH为8.0、接种量为11%、碳源是海藻糖、氮源是豆粕粉,最佳的培养基配方为海藻糖2.0%、豆粕粉3.5%、KH_2PO_4(0.05%)、MgSO_4(0.025%),该条件下菌球生物量最高为2.36g·100mL^(-1)。发酵菌丝体的三萜类化合物、β-葡聚糖和黄酮含量均高于子实体。[结论]通过对发酵工艺的筛选优化,为该菌的人工驯化和功能性食品开发奠定了基础。 展开更多
关键词 Fomitiporia yanbeiensis s. Guo&L. zhou 液体发酵 培养条件
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嗜蓝孢孔菌新种Fomitiporia yanbeiensis S.Guo & L.Zhou菌丝培养条件研究 被引量:6
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作者 郭尚 李艳婷 +3 位作者 周林 南晓洁 郭霄飞 刘晓钢 《安徽农学通报》 2017年第15期25-26,50,共3页
Fomitiporia yanbeiensis S.Guo&L.Zhou是从山西雁北地区沙棘腐木上分离获得的嗜蓝孢孔菌属的新种,这个种类具有特殊功能成分,具有很高的药用价值。该研究对其菌丝培养条件即温度、pH值、碳源营养、氮源营养进行了试验和分析。结果... Fomitiporia yanbeiensis S.Guo&L.Zhou是从山西雁北地区沙棘腐木上分离获得的嗜蓝孢孔菌属的新种,这个种类具有特殊功能成分,具有很高的药用价值。该研究对其菌丝培养条件即温度、pH值、碳源营养、氮源营养进行了试验和分析。结果表明,该菌菌丝体在人工培养基上容易生长,其最适生长温度为25℃,在最适温度下30d左右可长满平皿。最适培养条件:pH为6.0,碳源为葡萄糖,氮源为蛋白胨。这些结果为该菌的人工驯化栽培和功能食品开发提供了参考和依据。 展开更多
关键词 Fomitiporia yanbeiensis s.Guo&L.zhou 培养条件 温度 PH值 碳源 氮源
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The Zhou’s Method for Solving the Euler Equidimensional Equation
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作者 Pedro Pablo Cárdenas Alzate Jhon Jairo León Salazar Carlos Alberto Rodríguez Varela 《Applied Mathematics》 2016年第17期2165-2173,共9页
In this work, we apply the Zhou’s method [1] or differential transformation method (DTM) for solving the Euler equidimensional equation. The Zhou’s method may be considered as alternative and efficient for finding t... In this work, we apply the Zhou’s method [1] or differential transformation method (DTM) for solving the Euler equidimensional equation. The Zhou’s method may be considered as alternative and efficient for finding the approximate solutions of initial values problems. We prove superiority of this method by applying them on the some Euler type equation, in this case of order 2 and 3 [2]. The power series solution of the reduced equation transforms into an approximate implicit solution of the original equations. The results agreed with the exact solution obtained via transformation to a constant coefficient equation. 展开更多
关键词 zhous Method Equidimensional Equation Euler Equation DTM
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梓醇-川芎嗪方干预APPswe/PS1dE9双转基因阿尔茨海默病模型小鼠的作用机制研究
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作者 邓楚珺 孟胜喜 +4 位作者 陈慧泽 王兵 李文涛 潘卫东 张云云 《中西医结合心脑血管病杂志》 2023年第13期2412-2417,共6页
目的:探究梓醇-川芎嗪方干预APPswe/PS1dE9双转基因阿尔茨海默病模型小鼠的作用机制。方法:将3月龄C57BL/6J野生型小鼠为对照组(control组),构建阿尔茨海默病模型后,将同月龄APPswe/PS1dE9双转基因小鼠随机分为模型组(model组)、梓醇-... 目的:探究梓醇-川芎嗪方干预APPswe/PS1dE9双转基因阿尔茨海默病模型小鼠的作用机制。方法:将3月龄C57BL/6J野生型小鼠为对照组(control组),构建阿尔茨海默病模型后,将同月龄APPswe/PS1dE9双转基因小鼠随机分为模型组(model组)、梓醇-川芎嗪方低剂量组(CT-L组)、梓醇-川芎嗪方中剂量组(CT-M组)、梓醇-川芎嗪方高剂量(CT-H组)、安理申组,对照组及模型组均给予生理盐水灌胃,各用药组以相应药物灌胃,每日灌胃1次,连续8周。对各组小鼠进行行为学观察,检测各组小鼠海马组织乙酰胆碱酯酶(AChE)、诱导型一氧化氮合酶(iNOS)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、丙二醛(MDA)及血清中β淀粉样蛋白42(Aβ42)。结果:行为学观察:与model组比较,CT-M组、CT-H组、Arceipt组长时程学习和参考记忆能力、自主探究能力、情景识别记忆能力、短期工作记忆能力、条件恐惧记忆能力,缓解焦虑、抑郁状态等7项行为学指标均明显好转(P<0.01);与CT-L组比较,CT-M组、CT-H组、Arceipt组7项行为学指标均明显好转(P<0.05或P<0.01);与CT-M组比较,CT-H组7项行为学指标均明显好转(P<0.05);与Arceipt组比较,CT-H组7项行为学指标均明显好转(P<0.05)。生化检测方面:与model组比较,CT-M组、CT-H组、Arceipt组海马组织SOD、GSH-Px水平均升高,AChE活性、iNOS、IL-6、TNF-α、MDA水平及血清Aβ42水平均降低,差异均有统计学意义(P<0.01);与CT-L组比较,CT-M组、CT-H组、Arceipt组海马组织SOD、GSH-Px水平均升高,AChE活性、iNOS、IL-6、TNF-α、MDA水平及血清Aβ42水平均降低,差异均有统计学意义(P<0.05或P<0.01);与CT-M组比较,CT-H组海马组织SOD、GSH-Px水平均升高(P<0.05),AChE活性、iNOS、IL-6、TNF-α、MDA水平及血清Aβ42水平均降低(P<0.05);与Arceipt组比较,CT-H组海马组织SOD、GSH-Px水平均升高(P<0.05),AChE活性、iNOS、IL-6、TNF-α、MDA水平及血清Aβ42水平均降低(P<0.05)。结论:梓醇-川芎嗪方可以改善阿尔茨海默病模型小鼠的长时程学习和参考记忆能力、自主探究能力、情景识别记忆能力、短期工作记忆能力、条件恐惧记忆能力,缓解焦虑、抑郁状态,且其效应呈剂量依赖性,高剂量梓醇-川芎嗪方优于安理申。其作用机制可能与提高海马组织SOD、GSH-Px水平,降低AChE活性及iNOS、IL-6、TNF-α、MDA、Aβ42水平有关。 展开更多
关键词 阿尔茨海默病 梓醇-川芎嗪方 APPswe/Ps1dE9双转基因 动物行为学 氧化应激 实验研究
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A Modern Fairyland: On Mr. Zhou Tienong's Visit to Denmark
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作者 Shi Meiqi 《International Understanding》 2013年第3期40-42,共3页
At the invitation of the Danish-Chinese Business Forum(DCBF),Zhou Tienong,Vice-Chairman of the 11thNational People’s Congress Standing Committee and President of CAFIU,led a CAFIU delegation to visit Denmark from Jun... At the invitation of the Danish-Chinese Business Forum(DCBF),Zhou Tienong,Vice-Chairman of the 11thNational People’s Congress Standing Committee and President of CAFIU,led a CAFIU delegation to visit Denmark from June 9thto 12th.When we arrived in Copenhagen at 10:30 pm,looking at the skyline of the copper domes 展开更多
关键词 zhou Tienong’s Visit to Denmark A Modern Fairyland On Mr
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The Zhou’s Method for Solving the White-Dwarfs Equation
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作者 Pedro Pablo Cardenas Alzate William Ardila Uruena 《Applied Mathematics》 2013年第10期28-32,共5页
In this work we apply the differential transformation method (Zhou’s method) or DTM for solving white-dwarfs equation which Chandrasekhar [1] introduced in his study of the gravitational potential of these degenerate... In this work we apply the differential transformation method (Zhou’s method) or DTM for solving white-dwarfs equation which Chandrasekhar [1] introduced in his study of the gravitational potential of these degenerate (white-dwarf) stars. DTM may be considered as alternative and efficient for finding the approximate solutions of the initial values problems. We prove superiority of this method by applying them on the some Lane-Emden type equation, in this case. The power series solution of the reduced equation transforms into an approximate implicit solution of the original equation. 展开更多
关键词 zhous Method DTM Lane-Emden Type Equation White-Dwarfs
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Prof. Zhou Peiyuan, A Shining Star in China's Scientific and Educational Community
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作者 Zhang Daoyi(Institute of Science Popularization, CAST) 《Bulletin of the Chinese Academy of Sciences》 2002年第4期233-244,共12页
Prof. Zhou Peiyuan (P.Y.Chou) was a celebrated scientist, educationalist and social activist well-known both at home and abroad. He was an outstanding leader in the Chinese science and technology community, a founder ... Prof. Zhou Peiyuan (P.Y.Chou) was a celebrated scientist, educationalist and social activist well-known both at home and abroad. He was an outstanding leader in the Chinese science and technology community, a founder of modern mechanics in China, a fighter dedicated to world peace and an international envoy of peace and goodwill sent by the Chinese people as well as a peopleto-people diplomat for the promotion ofinternational exchange and cooperation in science and technology. 展开更多
关键词 A shining star in China’s scientific and Educational Community zhou Peiyuan sTAR
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Progress in Reform of China's Education and Pro tection of Citizens' Right to Educatio n ——An Interview with Zhou Ji, Minister of Education
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作者 BY OUR STAFF REPORTER 《The Journal of Human Rights》 2004年第3期2-6,共5页
Following is a transcript of an interview by our staff reporter with Zhou Ji, Minister of Education, on a range of questions concerning China's education. These include how China is reforming its education system,... Following is a transcript of an interview by our staff reporter with Zhou Ji, Minister of Education, on a range of questions concerning China's education. These include how China is reforming its education system, what the Chinese Government has done to protect the right of citizens to education, as well as the investment made by the state in education. 展开更多
关键词 Progress in Reform of China’s Education and Pro tection of Citizens An Interview with zhou Ji Right to Educatio n
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Zhou Enlai's Life Story Airson TV
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《China Today》 1998年第6期42-43,共2页
ZhouEnlai'sLifeStoryAirsonTVBystaffreporterZHANGXUEYINGONMarch5,1998,a12-partdocudra-maentitledEnlai.ACentur... ZhouEnlai'sLifeStoryAirsonTVBystaffreporterZHANGXUEYINGONMarch5,1998,a12-partdocudra-maentitledEnlai.ACenturyairedonBTV-1(cha... 展开更多
关键词 zhou Enlai’s Life story Airson TV
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论传承周恩来崇高精神为推进中国式现代化建设提供强大力量
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作者 韩同友 吴登全 任思远 《淮阴师范学院学报(哲学社会科学版)》 2024年第1期21-27,107,共8页
周恩来是社会主义现代化建设的开拓者、奠基者和推动者。坚守信仰、对党忠诚、热爱人民、自我革命、勇于担当、严于律己等六个方面是周恩来身上展现出来的崇高精神。周恩来的崇高精神,为中国式现代化筑牢了思想之基、政治之基、力量之... 周恩来是社会主义现代化建设的开拓者、奠基者和推动者。坚守信仰、对党忠诚、热爱人民、自我革命、勇于担当、严于律己等六个方面是周恩来身上展现出来的崇高精神。周恩来的崇高精神,为中国式现代化筑牢了思想之基、政治之基、力量之基、创新之基、实干之基和廉政之基,成为我们推进中国式现代化建设的强大力量。 展开更多
关键词 周恩来 崇高精神 中国式现代化
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周氏红鹿方联合甲磺酸多沙唑嗪缓释片治疗Ⅲ型慢性前列腺炎(湿热瘀阻型)的临床疗效观察
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作者 宋子希 曹宏文 +7 位作者 陈磊 高人杰 王丹 白慧明 李海滨 吴效通 赵文洋 冯懿赓 《中国性科学》 2024年第8期107-111,共5页
目的探讨周氏红鹿方联合甲磺酸多沙唑嗪缓释片治疗Ⅲ型慢性前列腺炎(湿热瘀阻型)的临床效果。方法选取2021年7月至2023年3月上海中医药大学附属龙华医院收治的80例Ⅲ型慢性前列腺炎(湿热瘀阻型)患者作为研究对象。采用随机数字表法分为... 目的探讨周氏红鹿方联合甲磺酸多沙唑嗪缓释片治疗Ⅲ型慢性前列腺炎(湿热瘀阻型)的临床效果。方法选取2021年7月至2023年3月上海中医药大学附属龙华医院收治的80例Ⅲ型慢性前列腺炎(湿热瘀阻型)患者作为研究对象。采用随机数字表法分为治疗组和对照组,每组40例。对照组采用甲磺酸多沙唑嗪缓释片治疗,治疗组在对照组基础上联合周氏红鹿方治疗。比较两组治疗前后美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)及前列腺液常规水平,比较两组临床疗效。结果治疗后,两组NIH-CPSI评分较治疗前显著降低,且治疗组低于对照组,差异具有统计学意义(P<0.05)。两组总有效率比较,差异具有统计学意义(P<0.05)。治疗后,两组白细胞计数(WBC)水平均低于治疗前,且治疗组低于对照组,差异具有统计学意义(P<0.05);治疗后,两组卵磷脂小体水平均增加,且治疗组大于对照组,差异具有统计学意义(P<0.05)。结论周氏红鹿方联合甲磺酸多沙唑嗪缓释片治疗Ⅲ型慢性前列腺炎(湿热瘀阻型)较单独西药的疗效更好,可显著缓解患者的临床症状,改善前列腺液常规水平。 展开更多
关键词 周氏红鹿方 甲磺酸多沙唑嗪缓释片 Ⅲ型慢性前列腺炎 湿热瘀阻型 临床疗效
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石氏温经强腰方结合中药熏蒸治疗腰椎间盘突出症(寒湿痹阻型)临床效果研究 被引量:1
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作者 赵旭涛 俞仲翔 《辽宁中医杂志》 CAS 北大核心 2024年第3期128-131,共4页
目的观察石氏温经强腰方结合中药熏蒸治疗腰椎间盘突出症(寒湿痹阻型)临床效果。方法将该院近1年收治的81例腰椎间盘突出症(寒湿痹阻型)患者纳入研究,根据治疗方法不同将其以随机数字表法分为对照组(40例)与中医组(41例),对照组患者采... 目的观察石氏温经强腰方结合中药熏蒸治疗腰椎间盘突出症(寒湿痹阻型)临床效果。方法将该院近1年收治的81例腰椎间盘突出症(寒湿痹阻型)患者纳入研究,根据治疗方法不同将其以随机数字表法分为对照组(40例)与中医组(41例),对照组患者采取西医常规疗法治疗,中医组患者在对照组患者治疗基础上结合石氏温经强腰方以及中药熏蒸治疗。比较临床治疗效果、治疗前后中医证候积分(腰腿冷痛着重、痛连臀腿、肢体发凉、舌质淡胖等)变化、C反应蛋白(C-reactive protein,CRP)以及肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)等炎症因子水平变化、疼痛量表[视觉模拟疼痛评分法(visual analogue scale,VAS)]评分变化、日本骨科协会评估治疗分数(Japanese Orthopaedic Associationscores,JOA评分)变化、不良反应。结果中医组患者治疗总有效率(95.12%,39/41)比对照组患者(80.00%,32/40)更高(P<0.05);治疗前,两组患者中医证候积分(腰腿冷痛着重、痛连臀腿、肢体发凉、舌质淡胖等)、CRP及TNF-α水平、VAS评分以及JOA评分等指标比较,差异无统计学意义(P>0.05),经治疗后两组患者中医证候积分(腰腿冷痛着重、痛连臀腿、肢体发凉、舌质淡胖等)、CRP及TNF-α水平、VAS评分均显著下降,中医组低于对照组,JOA评分均上升,中医组高于对照组(均P<0.05);对照组患者出现1例恶心,1例呕吐,中医组未见不良反应(P>0.05)。结论石氏温经强腰方结合中药熏蒸治疗腰椎间盘突出症(寒湿痹阻型)临床效果显著,患者症状好转,疼痛减轻,腰椎功能恢复好,且未见不良反应,安全可靠。 展开更多
关键词 腰椎间盘突出症 寒湿痹阻型 石氏温经强腰方 中药熏蒸 JOA评分
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中药Ⅰ号方对APP/PS1双转基因模型小鼠APP代谢的影响 被引量:3
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作者 隋小龙 梁良 +8 位作者 张玲 朱华 徐艳峰 黄澜 徐玉环 韩云林 姚志刚 秦川 邓巍 《中国实验动物学报》 CAS CSCD 2014年第6期49-53,I0004,I0005,共7页
目的研究中药I号方对APP/PS1双转基因模型小鼠APP代谢的影响。方法将5月龄APP/PS1双转基因模型小鼠随机分为模型组(vehicle)、中药Ⅰ号方低剂量组(0.6 g/kg)、中剂量组(1.2 g/kg)和高剂量组(2.4 g/kg),并以同窝阴性小鼠作为正常对照组(w... 目的研究中药I号方对APP/PS1双转基因模型小鼠APP代谢的影响。方法将5月龄APP/PS1双转基因模型小鼠随机分为模型组(vehicle)、中药Ⅰ号方低剂量组(0.6 g/kg)、中剂量组(1.2 g/kg)和高剂量组(2.4 g/kg),并以同窝阴性小鼠作为正常对照组(wild-type,WT),每组16只,雌雄各半。给药小鼠每天灌胃一次,模型组和正常对照组分别给予等体积的双蒸水灌胃。给药四个月后,用免疫组化和Western blot检测淀粉样前体蛋白(APP)及其代谢产物和分解酶的变化。结果 Western blot结果显示,与模型组相比,治疗组低剂量、中剂量和高剂量给药组能显著降低APP分解酶(ADAM10和BACE1)(P<0.01)及APP的分解产物的量,如:β-CTF(C99)、α-CTF(C83)、s APPα、s APPβ(P<0.01)。结论中药I号方通过影响APP的分解过程减少淀粉样蛋白(β-amyloid peptide,Aβ)的生成,减少脑内老年斑的沉积。 展开更多
关键词 中药Ⅰ号方 阿尔茨海默病 APP分解酶 APP/Ps1双转基因AD模型小鼠
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周惠芳教授治疗盆腔炎性疾病后遗症经验
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作者 狄丹华 张文燕 周惠芳 《山西中医药大学学报》 2024年第4期440-443,449,共5页
盆腔炎性疾病后遗症(SPID)是感染性疾病,以往称为慢性盆腔炎。周惠芳教授是江苏省名中医,从事妇科临床、教学及科研工作30余年,在治疗SPID方面积累了丰富的临床经验。周惠芳教授认为SPID乃本虚标实之证,总病机为正气已虚而余邪未净,湿... 盆腔炎性疾病后遗症(SPID)是感染性疾病,以往称为慢性盆腔炎。周惠芳教授是江苏省名中医,从事妇科临床、教学及科研工作30余年,在治疗SPID方面积累了丰富的临床经验。周惠芳教授认为SPID乃本虚标实之证,总病机为正气已虚而余邪未净,湿热、瘀滞为发病之标,正虚为发病之本,其中肾虚是核心。扶正祛邪是SPID的治疗总则,急性加重期以清利下焦、化瘀通络为主,自拟益肾清利方;缓解期补肾调周以扶正固本,佐以清利、化瘀。证情重者配合自拟灌肠方灌肠,内服外治,疗效显著。 展开更多
关键词 盆腔炎性疾病后遗症 中医药 名医经验 周惠芳
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周来兴教授胃2方治疗慢性胃炎医案举隅
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作者 王荣坡 潘志明 刘巧丽 《中国中医药现代远程教育》 2024年第8期84-85,共2页
周来兴教授系第三批、第六批全国老中医药专家学术指导老师、福建省名中医、国家基层名老中医,毕生致力于中医药的研究,尤其是脾胃疾病方面。胃2方是周来兴教授从医50余载对脾胃系统疾病深研所得。在临床实践中,该方用于慢性胃炎、胃食... 周来兴教授系第三批、第六批全国老中医药专家学术指导老师、福建省名中医、国家基层名老中医,毕生致力于中医药的研究,尤其是脾胃疾病方面。胃2方是周来兴教授从医50余载对脾胃系统疾病深研所得。在临床实践中,该方用于慢性胃炎、胃食管反流病均取得较满意效果。文章拟通过临床案例进一步说明周来兴教授胃2方对慢性胃炎的治疗作用。 展开更多
关键词 胃脘痛 慢性胃炎 周来兴 胃2方 医案
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基于数据挖掘探讨周继红治疗肺结节术后用药规律
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作者 黄燕玲 苏杉秧 +2 位作者 李文佳 卢相 周继红 《新中医》 CAS 2024年第14期8-13,共6页
目的:探讨周继红主任运用中医药治疗肺结节术后患者的用药特点及组方规律。方法:收集342例肺结节术后治疗处方,构建方药数据库。应用SPSS Modeler 18.0、SPSS Statistics 24.0对处方进行药物频次统计、关联规则分析及系统聚类。结果:共... 目的:探讨周继红主任运用中医药治疗肺结节术后患者的用药特点及组方规律。方法:收集342例肺结节术后治疗处方,构建方药数据库。应用SPSS Modeler 18.0、SPSS Statistics 24.0对处方进行药物频次统计、关联规则分析及系统聚类。结果:共纳入方剂372首,涉及中药194味,使用频次在150次以上(使用频率≥40%)的药物共有11味,具体为炙甘草、茯苓、麸炒白术、当归、黄芪、桔梗、法半夏、陈皮、麦冬、白芍、生地黄。在高频药物中归脾胃经的药物数量最多,达22味(73.3%);其次为归肺与大肠经的药物,有18味(60.0%);归肾经的药物最少,只有4味(13.3%)。关联规则分析(支持度≥10%,置信度≥85%,最大前项数1)得到关联规则71条,炙甘草与茯苓、麸炒白术与黄芪、茯苓与法半夏、炙甘草与当归等组合均为治疗肺结节术后常用药物组合。聚类分析得到7个组合,第1组以理气化痰类药物为主,包括竹茹、麸炒枳实、大枣等;第2组以活血祛瘀类药物为主,包括酒川芎、燀桃仁;第3组仅有1味炙甘草,以祛痰止咳、调和诸药为主要功效;第4组仅有1味茯神,以宁心安神为主要功效;第5组以益气固表类药物为主,包括麸炒白术、黄芪、防风;第6组以健脾养胃、清热散结、健脾利湿类药物为主,包括炒鸡内金、炒麦芽、太子参等;第7组以滋养肺肾、止咳化痰类药物为主,包括百合、玄参、浙贝母等。结论:治疗肺结节术后患者以滋肾补肺、益气固表、行气化痰、活血补血为基本原则,从脾胃论治肺系疾病是其用药特点之一。 展开更多
关键词 肺结节术后 中药处方 数据挖掘 用药规律 周继红
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