A mixed complex [Zn（C5H6N2）（HL）2] （C5H6N2 = 2-aminopyridine, H2L = acetylacetone） has been synthesized and characterized by IR, elemental analysis and X-ray single-crystal diffraction analysis. The crystal belon...A mixed complex [Zn（C5H6N2）（HL）2] （C5H6N2 = 2-aminopyridine, H2L = acetylacetone） has been synthesized and characterized by IR, elemental analysis and X-ray single-crystal diffraction analysis. The crystal belongs to monoclinic, space group P21/c with a = 7.4490（15）, b = 8.2650（17）, c = 27.615（6） A°, β= 101.69（3）°, V = 1664.9（6）A°^3, Z = 4, Mr = 357.70, Dc = 1.427 g/cm^3, F（000） = 744, μ = 1.493 mm^-1, R = 0.0309 and wR = 0.0771. The Zn（Ⅱ） is coordinated by one nitrogen atom from 2-aminopyridine and four oxygen atoms from two acetylacetone anions to furnish a distorted square pyramid geometry. The complex forms a three-dimensional network through intermolecular hydrogen bonds.展开更多
A novel Zn（Ⅱ） complex, [ZnL2（H2O）4]·H2O（1, HL = 2-（nicotinoyloxy）acetic acid）, was synthesized using Zn（OAc）2·2H2O and 2-（nicotinoyloxy）acetic acid as raw materials. Its structure has been eluci...A novel Zn（Ⅱ） complex, [ZnL2（H2O）4]·H2O（1, HL = 2-（nicotinoyloxy）acetic acid）, was synthesized using Zn（OAc）2·2H2O and 2-（nicotinoyloxy）acetic acid as raw materials. Its structure has been elucidated by elemental analysis, IR and single-crystal X-ray diffraction. The structural analysis revealed that complex 1 crystallizes in triclinic, space group P1 and the Zn（Ⅱ） atom is six-coordinated with two N atoms from two different 2-（nicotinoyloxy）acetate anion ligands and four O atoms from coordinated water molecules. Complex 1 forms a 3D network structure by O–H···O hydrogen bonds. The antitumor activities of 2-（nicotinoyloxy）acetic acid ligand and its Zn（Ⅱ） complex were evaluated against human lung adenocarcinoma A549 cells, human hepatoma SMMC-7721 cells and human colon carcinoma Wi Dr cells.展开更多
A new complex has been synthesized with o-methylbenzoyl-benzoic acid（HL） and 1,10-phenanthroline（phen） in the mixture of water and ethanol. It crystallizes in monoclinic, space group C2/c with a = 13.6328（18）, b...A new complex has been synthesized with o-methylbenzoyl-benzoic acid（HL） and 1,10-phenanthroline（phen） in the mixture of water and ethanol. It crystallizes in monoclinic, space group C2/c with a = 13.6328（18）, b = 17.7876（18）, c = 19.998（2）, β = 104.720（4）o, C54H48N4O11Zn, Mr = 994.33, V = 4690.2（9）3, Dc = 1.408 g/cm3, Z = 4, F（000） = 2072, μ（MoKα） = 0.59 mm-1, R = 0.0736 and wR = 0.2029. The crystal structure shows that the zinc ions are coordinated with two oxygen atoms from two HL molecules and four nitrogen atoms from two phen molecules, forming distorted octahedral coordination geometry. The fluorescent and thermal stability properties of the complex are studied. The result shows that it has one fluorescent emission band at around 412 nm. In addition, the complex is stable under 210 ℃.展开更多
The novel complex [Zn2（Mba）3（Phen）2EtOH）]·ClO4 （Hrnba = methoxybenzoic acid, Phen = 1,10-phenanthroline, EtOH = ethanol） was synthesized by hydrothermal reactions, and its structure was determined by X-ray...The novel complex [Zn2（Mba）3（Phen）2EtOH）]·ClO4 （Hrnba = methoxybenzoic acid, Phen = 1,10-phenanthroline, EtOH = ethanol） was synthesized by hydrothermal reactions, and its structure was determined by X-ray diffraction. The crystal belongs to the triclinic system, space group Pi with a = 1.15362（1）, b = 1.3655（3）, c = 1.61451（1） nm, α= 72.842（2）, β = 83.259（3）, y = 72.083（2）°, V = 2.3112（6） nm3, Z = 2,μ（MoKa） = 11.71 cm-1, F（000） = 1120, R = 0.0552 and wR = 0.1157 （I 〉 2σ（I））. The two centric zinc（H） ions in the complex locate in a distorted octahedral coordination geometry and a distorted trigonal bipyramid coordination geometry, respectively. Two bridging bidentate carboxyl groups and a μ2-O carboxyl group from three methoxybenzoic acids act as the bridge to link two Zn（Ⅱ） ions. The asymmetric units are connected by π-π packing interactions between aromatic rings to form a three-dimensional supramolecular network. The experimental results show a good fluorescence property for the complex.展开更多
A new tetranuclear zinc（II） complex [Zn4（SO4）2（DPPZ）4（HSal）2（OH）2] 1 （DPPZ = dipyrido[3,2-a：2＇,3＇-c]phenazine, H2Sal = salicylic acid） was prepared by using hydrothermal synthesis and characterized by e...A new tetranuclear zinc（II） complex [Zn4（SO4）2（DPPZ）4（HSal）2（OH）2] 1 （DPPZ = dipyrido[3,2-a：2＇,3＇-c]phenazine, H2Sal = salicylic acid） was prepared by using hydrothermal synthesis and characterized by elemental analysis, IR spectrum, thermal gravimetry （TG）, fluorescent emission and single-crystal X-ray diffraction. Its crystal structure is of monoclinic, space group P2 1/c with a = 9.8897（8）, b = 14.2506（12）, c = 26.384（2） ,A, β = 94.8940（10）°, V = 3704.8（5） A3 Z = 2, C86H52N16O16S2Zn4, Mr = 1891.04, Dc = 1.695 g/cm^3, μ= 1.423 mm^-1, F（000） = 1920, GOOF = 1.039, the final R = 0.0358 and wR = 0.0872 for 6038 observed reflections with I 〉 2σ（I）. In 1, ＂cage-like＂ tetranuclear clusters of [Zn4（SO4）2（DPPZ）4（HSal）2（OH）2] are further stacked through π-π interactions to generate a 3D supramolecular network.展开更多
A new Zn（Ⅱ） complex, [Zn（L）2（phen）（H2O）]（1, HL = N-acetyl-L-phenylalanine, phen = 1,10-phenanthroline） has been synthesized and characterized by elemental analysis, IR and X-ray single-crystal diffraction a...A new Zn（Ⅱ） complex, [Zn（L）2（phen）（H2O）]（1, HL = N-acetyl-L-phenylalanine, phen = 1,10-phenanthroline） has been synthesized and characterized by elemental analysis, IR and X-ray single-crystal diffraction analysis. The Zn（Ⅱ） complex belongs to monoclinic, space group P21 with a = 12.6749（13）, b = 5.5965（6）, c = 22.985（2） A, β = 104.296（2）°, V = 1580.0（3） A^3, Z = 2, Mr = 676.02, Dc = 1.421 μg·m^（-3）, μ = 0.833 mm^-1, F（000） = 704, and the final R = 0.0460, wR = 0.0899 for 4422 observed reflections with I 〉 2σ（I）. The molecules form a 1D chained structure by hydrogen bonds. The antitumor activities of Zn（Ⅱ） complex against human hepatoma SMMC-7721 cells, human lung adenocarcinoma A549 cells and human colon carcinoma WiDr cells have also been investigated.展开更多
A novel complex, [Zn（L）]2·H2O（1, H2 L = 4-aminophthalic acid）, has been hydrothermally prepared and characterized by single-crystal X-ray diffraction, IR spectroscopy, elemental analysis and PXRD. Complex 1 c...A novel complex, [Zn（L）]2·H2O（1, H2 L = 4-aminophthalic acid）, has been hydrothermally prepared and characterized by single-crystal X-ray diffraction, IR spectroscopy, elemental analysis and PXRD. Complex 1 crystallizes in monoclinic, space group C2/c with a = 12.4267（6）, b = 7.7482（3）, c = 18.6983（8） A, β = 110.437（3）°, V = 1687.04（13） A3, Z = 4, C16H12N2O9Zn2, Mr = 507.06, Dc = 1.996 g/cm3, μ = 2.903 mm-1, S = 0.989, F（000） = 1016, the final R = 0.0304 and w R = 0.0720 for 12618 observed reflections（I 〉 2σ（I））. Single-crystal X-ray structural analysis reveals that compound 1 features a three-dimensional（3D） framework with 4-connected umc topology. Moreover, the thermogravimetric（TG） analysis and photoluminescent property of 1 were also discussed.展开更多
A new binuclear Zn^Ⅱ coordination complex,Zn2（bta）（phen）2（Cl）3（1,Hbta = 2-（1Hbenzotriazol-1-yl）acetic acid and phen = 1,10-phenanthroline）,has been synthesized and characterized by single-crystal X-ray diff...A new binuclear Zn^Ⅱ coordination complex,Zn2（bta）（phen）2（Cl）3（1,Hbta = 2-（1Hbenzotriazol-1-yl）acetic acid and phen = 1,10-phenanthroline）,has been synthesized and characterized by single-crystal X-ray diffraction,IR spectroscopy,elemental,and photoluminescent analysis.Complex 1 crystallizes in triclinic system,space group P1 with a = 9.3040（19）,b = 10.694（2）,c =16.841（3） A°,α = 101.18（3）,β = 105.77（3）,γ = 91.72（3）°,V= 1575.8（5） A°3,C（32）H（22）Zn2Cl3N7O2,Mr =773.66,Dc = 1.631 g/cm^3,Z = 2,F（000） = 780,μ = 1.820 mm^-1,the final R = 0.1238 and wR =0.1131.X-ray diffraction analyses indicate that 1 displays two crystallographic independent Zn^Ⅱmetal centers with a distorted tetragonal pyramidal（ZnN4O） and a tetrahedral（ZnNCl3） geometries,respectively.The phen serves as a common N,N＇-bidentate ligand,and the bta^- as a unique N,O-bridged ligand in 1.In the crystal,1 forms a stable 3D supramolecular architecture by trifurcated hydrogen bonding C-H…C1 interactions and C-H…π,π…π stacking.1 showed photo-electric conversion properties.展开更多
The electrospray ionization mass spectrometry investigation showed that the binding sites of [ZnL]^2＋, where L is 2-[bis（2- aminoethyl）amino]ethanol, with oxidized insulin B chain are Phel, His5 and Arg22, which le...The electrospray ionization mass spectrometry investigation showed that the binding sites of [ZnL]^2＋, where L is 2-[bis（2- aminoethyl）amino]ethanol, with oxidized insulin B chain are Phel, His5 and Arg22, which lead to the selective cleavages of the peptide bonds at Phe1-Val2, His5-Leu6, Glu21-Arg22, and Arg22-Gly23 of oxidized insulin B chain.展开更多
A new Zn（II） complex, [ZnL2Br2] （L = triadimenol） was synthesized by the reaction of ZnBr2 with the commercial fungicide of triadimenol, then characterized by elemental analysis, IR spectroscopy and single-crystal...A new Zn（II） complex, [ZnL2Br2] （L = triadimenol） was synthesized by the reaction of ZnBr2 with the commercial fungicide of triadimenol, then characterized by elemental analysis, IR spectroscopy and single-crystal X-ray diffraction. The crystal structure shows that the complex [ZnL2Br2] crystallizes in orthorhombic, Pnam space group with a = 11.263（2）, b = 8.4478（15）, c = 36.125 （7） A, V = 3437.2 （11 ） ,A Z = 4, C28H36Br2C12N604Zn, Mr = 816.72, Dc = 1.578 g/cm3, F（000） = 1648,μ = 3.236 mm-1, the final R = 0.0388 and wR = 0.0879 for 2399 observed reflections with I 〉 2σ（/）. The central metals adopt square plane coordination geometry. And intermolecular hydrogen bonds connect Zn（Ⅱ） into a one-dimensional chain. In addition, the title complex and triadimenol were screened for antifungal activities against four selected fungi using the mycelial growth rate method. The results indicate that the complex synthesized shows better antifungal activities than the ligand triadimenol.展开更多
A potentiometric study on the complexes of His,Gly-His,ALa-His,Gly-Gly and Gly—Gly—Gly with Zn(Ⅱ)and Cd(Ⅱ)has been reported.Small-scale potentiometric titrations were car- ried out to determine stabil ity constant...A potentiometric study on the complexes of His,Gly-His,ALa-His,Gly-Gly and Gly—Gly—Gly with Zn(Ⅱ)and Cd(Ⅱ)has been reported.Small-scale potentiometric titrations were car- ried out to determine stabil ity constants of complexes at 25℃ with I=0.10 mol dm^(-3)(KNO_3).The com- puter programs SUPERQUAD were applied for data treatment with satisfactory results.展开更多
基金This work was supported by Qingdao Science and Technology Plan Items (03-3-nsh-28)
文摘A mixed complex [Zn（C5H6N2）（HL）2] （C5H6N2 = 2-aminopyridine, H2L = acetylacetone） has been synthesized and characterized by IR, elemental analysis and X-ray single-crystal diffraction analysis. The crystal belongs to monoclinic, space group P21/c with a = 7.4490（15）, b = 8.2650（17）, c = 27.615（6） A°, β= 101.69（3）°, V = 1664.9（6）A°^3, Z = 4, Mr = 357.70, Dc = 1.427 g/cm^3, F（000） = 744, μ = 1.493 mm^-1, R = 0.0309 and wR = 0.0771. The Zn（Ⅱ） is coordinated by one nitrogen atom from 2-aminopyridine and four oxygen atoms from two acetylacetone anions to furnish a distorted square pyramid geometry. The complex forms a three-dimensional network through intermolecular hydrogen bonds.
基金supported by the National Natural Science Foundation of China(No.21171132)the Project of Shandong Province Higher Educational Science and Technology Program(J14LC01)Science Foundation of Weifang
文摘A novel Zn（Ⅱ） complex, [ZnL2（H2O）4]·H2O（1, HL = 2-（nicotinoyloxy）acetic acid）, was synthesized using Zn（OAc）2·2H2O and 2-（nicotinoyloxy）acetic acid as raw materials. Its structure has been elucidated by elemental analysis, IR and single-crystal X-ray diffraction. The structural analysis revealed that complex 1 crystallizes in triclinic, space group P1 and the Zn（Ⅱ） atom is six-coordinated with two N atoms from two different 2-（nicotinoyloxy）acetate anion ligands and four O atoms from coordinated water molecules. Complex 1 forms a 3D network structure by O–H···O hydrogen bonds. The antitumor activities of 2-（nicotinoyloxy）acetic acid ligand and its Zn（Ⅱ） complex were evaluated against human lung adenocarcinoma A549 cells, human hepatoma SMMC-7721 cells and human colon carcinoma Wi Dr cells.
基金Supported by the Natural Science Foundation of Hunan Province(No.11JJ9006)Key Project of Science and Technology Plan of Hunan Province(2012FJ2002)the Construct Program of the Key Discipline in Hunan Province
文摘A new complex has been synthesized with o-methylbenzoyl-benzoic acid（HL） and 1,10-phenanthroline（phen） in the mixture of water and ethanol. It crystallizes in monoclinic, space group C2/c with a = 13.6328（18）, b = 17.7876（18）, c = 19.998（2）, β = 104.720（4）o, C54H48N4O11Zn, Mr = 994.33, V = 4690.2（9）3, Dc = 1.408 g/cm3, Z = 4, F（000） = 2072, μ（MoKα） = 0.59 mm-1, R = 0.0736 and wR = 0.2029. The crystal structure shows that the zinc ions are coordinated with two oxygen atoms from two HL molecules and four nitrogen atoms from two phen molecules, forming distorted octahedral coordination geometry. The fluorescent and thermal stability properties of the complex are studied. The result shows that it has one fluorescent emission band at around 412 nm. In addition, the complex is stable under 210 ℃.
基金Supported by the Scientific and Technological Program of Hunan Provincial Department of Science and Technology (No. 2010JT4041)Hunan Provincial Department of Education (No. 11C0186)Hunan Provincial Key Discipline Construction and Hunan College Key Laboratory of Functional Organometallic Materials
文摘The novel complex [Zn2（Mba）3（Phen）2EtOH）]·ClO4 （Hrnba = methoxybenzoic acid, Phen = 1,10-phenanthroline, EtOH = ethanol） was synthesized by hydrothermal reactions, and its structure was determined by X-ray diffraction. The crystal belongs to the triclinic system, space group Pi with a = 1.15362（1）, b = 1.3655（3）, c = 1.61451（1） nm, α= 72.842（2）, β = 83.259（3）, y = 72.083（2）°, V = 2.3112（6） nm3, Z = 2,μ（MoKa） = 11.71 cm-1, F（000） = 1120, R = 0.0552 and wR = 0.1157 （I 〉 2σ（I））. The two centric zinc（H） ions in the complex locate in a distorted octahedral coordination geometry and a distorted trigonal bipyramid coordination geometry, respectively. Two bridging bidentate carboxyl groups and a μ2-O carboxyl group from three methoxybenzoic acids act as the bridge to link two Zn（Ⅱ） ions. The asymmetric units are connected by π-π packing interactions between aromatic rings to form a three-dimensional supramolecular network. The experimental results show a good fluorescence property for the complex.
基金Supported by the Natural Science Foundation of Jilin Province (No. 20060516)the Doctoral Foundation of Jilin Normal University (No. 2006006 and No. 2007009)+1 种基金the Science and Technology Institute Foundation of Siping City (No. 2005016)the Subject and Base Construction Foundation of Jilin Normal University (No. 2006041)
文摘A new tetranuclear zinc（II） complex [Zn4（SO4）2（DPPZ）4（HSal）2（OH）2] 1 （DPPZ = dipyrido[3,2-a：2＇,3＇-c]phenazine, H2Sal = salicylic acid） was prepared by using hydrothermal synthesis and characterized by elemental analysis, IR spectrum, thermal gravimetry （TG）, fluorescent emission and single-crystal X-ray diffraction. Its crystal structure is of monoclinic, space group P2 1/c with a = 9.8897（8）, b = 14.2506（12）, c = 26.384（2） ,A, β = 94.8940（10）°, V = 3704.8（5） A3 Z = 2, C86H52N16O16S2Zn4, Mr = 1891.04, Dc = 1.695 g/cm^3, μ= 1.423 mm^-1, F（000） = 1920, GOOF = 1.039, the final R = 0.0358 and wR = 0.0872 for 6038 observed reflections with I 〉 2σ（I）. In 1, ＂cage-like＂ tetranuclear clusters of [Zn4（SO4）2（DPPZ）4（HSal）2（OH）2] are further stacked through π-π interactions to generate a 3D supramolecular network.
基金supported by the National Natural Science Foundation of China(No.21171132)the Project of Shandong Province Higher Educational Science and Technology Program(J14LC01)Science Foundation of Weifang
文摘A new Zn（Ⅱ） complex, [Zn（L）2（phen）（H2O）]（1, HL = N-acetyl-L-phenylalanine, phen = 1,10-phenanthroline） has been synthesized and characterized by elemental analysis, IR and X-ray single-crystal diffraction analysis. The Zn（Ⅱ） complex belongs to monoclinic, space group P21 with a = 12.6749（13）, b = 5.5965（6）, c = 22.985（2） A, β = 104.296（2）°, V = 1580.0（3） A^3, Z = 2, Mr = 676.02, Dc = 1.421 μg·m^（-3）, μ = 0.833 mm^-1, F（000） = 704, and the final R = 0.0460, wR = 0.0899 for 4422 observed reflections with I 〉 2σ（I）. The molecules form a 1D chained structure by hydrogen bonds. The antitumor activities of Zn（Ⅱ） complex against human hepatoma SMMC-7721 cells, human lung adenocarcinoma A549 cells and human colon carcinoma WiDr cells have also been investigated.
基金supported by the National Natural Science Foundation of China(Nos.21171040 and 21302019)excellent organic teaching and research project(No.2013JCJS01)National Undergraduates Innovation Project(201510371010)
文摘A novel complex, [Zn（L）]2·H2O（1, H2 L = 4-aminophthalic acid）, has been hydrothermally prepared and characterized by single-crystal X-ray diffraction, IR spectroscopy, elemental analysis and PXRD. Complex 1 crystallizes in monoclinic, space group C2/c with a = 12.4267（6）, b = 7.7482（3）, c = 18.6983（8） A, β = 110.437（3）°, V = 1687.04（13） A3, Z = 4, C16H12N2O9Zn2, Mr = 507.06, Dc = 1.996 g/cm3, μ = 2.903 mm-1, S = 0.989, F（000） = 1016, the final R = 0.0304 and w R = 0.0720 for 12618 observed reflections（I 〉 2σ（I））. Single-crystal X-ray structural analysis reveals that compound 1 features a three-dimensional（3D） framework with 4-connected umc topology. Moreover, the thermogravimetric（TG） analysis and photoluminescent property of 1 were also discussed.
基金supported by Guangxi Provincial Department of Education(No.KY2015ZD130)the Natural Science Foundation of Guangxi Province(No.2013GXNSFBA019030)the financial support from the Natural Science Foundation of Qinzhou University(No.2014PY-GJ05)
文摘A new binuclear Zn^Ⅱ coordination complex,Zn2（bta）（phen）2（Cl）3（1,Hbta = 2-（1Hbenzotriazol-1-yl）acetic acid and phen = 1,10-phenanthroline）,has been synthesized and characterized by single-crystal X-ray diffraction,IR spectroscopy,elemental,and photoluminescent analysis.Complex 1 crystallizes in triclinic system,space group P1 with a = 9.3040（19）,b = 10.694（2）,c =16.841（3） A°,α = 101.18（3）,β = 105.77（3）,γ = 91.72（3）°,V= 1575.8（5） A°3,C（32）H（22）Zn2Cl3N7O2,Mr =773.66,Dc = 1.631 g/cm^3,Z = 2,F（000） = 780,μ = 1.820 mm^-1,the final R = 0.1238 and wR =0.1131.X-ray diffraction analyses indicate that 1 displays two crystallographic independent Zn^Ⅱmetal centers with a distorted tetragonal pyramidal（ZnN4O） and a tetrahedral（ZnNCl3） geometries,respectively.The phen serves as a common N,N＇-bidentate ligand,and the bta^- as a unique N,O-bridged ligand in 1.In the crystal,1 forms a stable 3D supramolecular architecture by trifurcated hydrogen bonding C-H…C1 interactions and C-H…π,π…π stacking.1 showed photo-electric conversion properties.
文摘The electrospray ionization mass spectrometry investigation showed that the binding sites of [ZnL]^2＋, where L is 2-[bis（2- aminoethyl）amino]ethanol, with oxidized insulin B chain are Phel, His5 and Arg22, which lead to the selective cleavages of the peptide bonds at Phe1-Val2, His5-Leu6, Glu21-Arg22, and Arg22-Gly23 of oxidized insulin B chain.
基金the National Natural Science Foundation(21373161)New Century Excellent Talents in University of Ministry of Education of China(NCET-12-1047)
文摘A new Zn（II） complex, [ZnL2Br2] （L = triadimenol） was synthesized by the reaction of ZnBr2 with the commercial fungicide of triadimenol, then characterized by elemental analysis, IR spectroscopy and single-crystal X-ray diffraction. The crystal structure shows that the complex [ZnL2Br2] crystallizes in orthorhombic, Pnam space group with a = 11.263（2）, b = 8.4478（15）, c = 36.125 （7） A, V = 3437.2 （11 ） ,A Z = 4, C28H36Br2C12N604Zn, Mr = 816.72, Dc = 1.578 g/cm3, F（000） = 1648,μ = 3.236 mm-1, the final R = 0.0388 and wR = 0.0879 for 2399 observed reflections with I 〉 2σ（/）. The central metals adopt square plane coordination geometry. And intermolecular hydrogen bonds connect Zn（Ⅱ） into a one-dimensional chain. In addition, the title complex and triadimenol were screened for antifungal activities against four selected fungi using the mycelial growth rate method. The results indicate that the complex synthesized shows better antifungal activities than the ligand triadimenol.
文摘A potentiometric study on the complexes of His,Gly-His,ALa-His,Gly-Gly and Gly—Gly—Gly with Zn(Ⅱ)and Cd(Ⅱ)has been reported.Small-scale potentiometric titrations were car- ried out to determine stabil ity constants of complexes at 25℃ with I=0.10 mol dm^(-3)(KNO_3).The com- puter programs SUPERQUAD were applied for data treatment with satisfactory results.
