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常规QA设备对脊柱转移瘤SRS/SBRT计划的验证及存在问题探讨 被引量:1
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作者 郭逸潇 刘志强 +3 位作者 李鸿岩 冯维贵 张致远 李淑萍 《中国医学物理学杂志》 CSCD 2021年第12期1464-1471,共8页
目的:对比aSi-1200 EPID与Octavius 1500电离室矩阵在6 MV非均整脊柱转移瘤计划验证中的应用,探讨可能存在的问题。方法:23例计划在全局归一方式下以不同标准和阈值行2Dγ通过率(GPR)评估,将治疗计划系统(TPS)中患者数据导入Verisoft软... 目的:对比aSi-1200 EPID与Octavius 1500电离室矩阵在6 MV非均整脊柱转移瘤计划验证中的应用,探讨可能存在的问题。方法:23例计划在全局归一方式下以不同标准和阈值行2Dγ通过率(GPR)评估,将治疗计划系统(TPS)中患者数据导入Verisoft软件重建剂量。引入不同类型和量值的误差:MLC的透射率(TF)和剂量叶片间隙(DLG)、治疗等中心和MU误差,使用GPR方法量化Octavius 1500识别这些误差的灵敏度,并通过评估靶区和危及器官(OARs)剂量学指标变化研究TF和DLG误差的临床意义。结果:与Octavius 1500矩阵相比,EPID方式在同一标准不同阈值下GPR均值更大数据离散程度更小,重建与计算的剂量体积直方图分析表明临床靶区和计划靶区D_(min)、D_(max)和D_(mean)的百分剂量偏差(DD%)较大,其中临床靶区最大DD%值为50.00%、11.31%和-8.71%,计划靶区最大DD%值为-25.86%、9.31%和-8.22%。治疗等中心和+3%、+5%的MU误差都被检测到,所有标准均未检测到TF误差,+0.3 mm的DLG误差只被2%/3 mm的标准检测到。TF值增大0.0236%模型误差和DLG增加0.3 mm模型误差均导致靶区和OARs的剂量增加,其中OARs剂量增加较明显,尤其健侧肺的V_(20)分别增加9.80%和8.85%,脊髓D_(0.1 cc)均增加5.35%。结论:使用GPR方法识别引入误差的MLC模型可靠性不够,提示鉴别TPS问题的根源需要更有效的独立质量保证方法以确保通过TPS计算得出的陡峭剂量梯度的可信度。剂量验证系统软件算法的独立验证研究是有必要的,以确定算法局限性导致的重建剂量不确定性范围。 展开更多
关键词 脊柱转移瘤 aSi-1200 EPID Octavius 1500 剂量验证 透射率 剂量叶片间隙
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Performance Evaluation of the Siemens Electronic Portal Imaging Device for IMRT Plan Verification
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作者 Y. A. M. Yousif A. J. Van Rensburg 《International Journal of Medical Physics, Clinical Engineering and Radiation Oncology》 2015年第3期215-223,共9页
A commercially available amorphous Silicon Electronic Portal imaging device (aSi-EPID) installed onto Siemens Oncor Linear accelerator was evaluated with the objective to be implemented for IMRT quality assurance. EPI... A commercially available amorphous Silicon Electronic Portal imaging device (aSi-EPID) installed onto Siemens Oncor Linear accelerator was evaluated with the objective to be implemented for IMRT quality assurance. EPID properties were investigated;these include reproducibility, dependences between the relative EPID responses and field size, dose rate were studied for both photon beams. To determine the inherent build-up of the EPID, varied thickness of Solid-water was placed onto the detector surface and changes in EPID signals were investigated. EPID measurements were compared with ionization chamber measurements (type 30013) connected to a UNIDOS electrometer (PTW-Freiberg) in Water phantom. The use of EPID dose maps was tested by comparing it with TPS-calculated one for IMRT plan applying gamma criteria of 3%/3mm. The results demonstrated that the aSi-EPID signals were reproducible, and response to the applied MUs were linear up to 100 MUs, and then the response became stable for MUs higher than 200, detector should be calibrated in this range. The results showed a clear dependency on the field size and energy. The dosimetric properties measured in this work shows promise that the aSi-EPID can be used for IMRT verifications. 展开更多
关键词 IMRT asi-epid MONITOR Unit Field-Size DOSE Rate
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