AIM:To evaluate the efficacy of custom-made soft keratoconus(KC)lenses on corneal aberrations and photic phenomena in two different optical zones in patients with KC.METHODS:Sixty eyes of 42 patients with KC were exam...AIM:To evaluate the efficacy of custom-made soft keratoconus(KC)lenses on corneal aberrations and photic phenomena in two different optical zones in patients with KC.METHODS:Sixty eyes of 42 patients with KC were examined at baseline and after fitting HydroCone(Toris K)soft silicone hydrogel lenses.Best spectacle-corrected visual acuity(BSCVA)and contact lens-corrected visual acuity(CLCVA)were recorded.Lower-and higher-order corneal aberrations(LOAs and HOAs)were measured with and without Toris K lenses and compared in central 4.5 mm and 7 mm zones.Mesopic pupil diameter and subjective photic phenomena were also assessed.RESULTS:Mean CLCVA was significantly improved compared to BSCVA(P<0.0001).Corneal curvature and refractive measurements were found to be significantly reduced by the use of Toris K lenses,except for posterior corneal curvature values.In the 4.5 mm central optical zone,all wavefront aberrations decreased significantly after lens fitting(P<0.0001).In contrast,in the 7 mm(peripheral)optical zone,values for HOAs,spherical and residual aberrations,and optical path differences were increased,while LOAs,trefoil,and quadrifoil coefficients were decreased.The rate of photic phenomena was significantly higher in participants with a pupil size>6.00 mm(85.7%).CONCLUSION:Toris K lenses provide good visual results and a significant reduction in central corneal aberrations in patients with KC but could cause an increase in peripheral aberrations.This practical and nonsurgical approach appears to be an effective method for the visual management of KC.展开更多
离轴反射系统设计的关键环节是确定适用初始结构并进行优化,一般从同轴结构或者专利库中寻找相似的结构开始优化,这往往需要耗费大量的时间。以Seidel像差理论为依据,研究了一种获取离轴四反系统初始结构的设计方法。在设计之初引入视...离轴反射系统设计的关键环节是确定适用初始结构并进行优化,一般从同轴结构或者专利库中寻找相似的结构开始优化,这往往需要耗费大量的时间。以Seidel像差理论为依据,研究了一种获取离轴四反系统初始结构的设计方法。在设计之初引入视场偏置,通过追迹近轴光线给出五种单色像差的初级Seidel像差表示。以Seidel像差绝对值最小化作为目标函数,同时加入对光学和系统结构上的限制条件构建含有约束条件的单目标非线性优化模型,并通过粒子群优化算法进行求解。在此基础上,通过MATLAB调用CODE V API接口,判断此视场偏置情况下是否满足无遮拦的条件,并从中挑选出满足条件的初始结构。设计了一款焦距为1200 mm,视场1.2°×20°,F数为6的离轴四反光学系统,系统结构布局紧凑,成像质量良好,各项指标均满足设计要求。展开更多
文摘AIM:To evaluate the efficacy of custom-made soft keratoconus(KC)lenses on corneal aberrations and photic phenomena in two different optical zones in patients with KC.METHODS:Sixty eyes of 42 patients with KC were examined at baseline and after fitting HydroCone(Toris K)soft silicone hydrogel lenses.Best spectacle-corrected visual acuity(BSCVA)and contact lens-corrected visual acuity(CLCVA)were recorded.Lower-and higher-order corneal aberrations(LOAs and HOAs)were measured with and without Toris K lenses and compared in central 4.5 mm and 7 mm zones.Mesopic pupil diameter and subjective photic phenomena were also assessed.RESULTS:Mean CLCVA was significantly improved compared to BSCVA(P<0.0001).Corneal curvature and refractive measurements were found to be significantly reduced by the use of Toris K lenses,except for posterior corneal curvature values.In the 4.5 mm central optical zone,all wavefront aberrations decreased significantly after lens fitting(P<0.0001).In contrast,in the 7 mm(peripheral)optical zone,values for HOAs,spherical and residual aberrations,and optical path differences were increased,while LOAs,trefoil,and quadrifoil coefficients were decreased.The rate of photic phenomena was significantly higher in participants with a pupil size>6.00 mm(85.7%).CONCLUSION:Toris K lenses provide good visual results and a significant reduction in central corneal aberrations in patients with KC but could cause an increase in peripheral aberrations.This practical and nonsurgical approach appears to be an effective method for the visual management of KC.
文摘离轴反射系统设计的关键环节是确定适用初始结构并进行优化,一般从同轴结构或者专利库中寻找相似的结构开始优化,这往往需要耗费大量的时间。以Seidel像差理论为依据,研究了一种获取离轴四反系统初始结构的设计方法。在设计之初引入视场偏置,通过追迹近轴光线给出五种单色像差的初级Seidel像差表示。以Seidel像差绝对值最小化作为目标函数,同时加入对光学和系统结构上的限制条件构建含有约束条件的单目标非线性优化模型,并通过粒子群优化算法进行求解。在此基础上,通过MATLAB调用CODE V API接口,判断此视场偏置情况下是否满足无遮拦的条件,并从中挑选出满足条件的初始结构。设计了一款焦距为1200 mm,视场1.2°×20°,F数为6的离轴四反光学系统,系统结构布局紧凑,成像质量良好,各项指标均满足设计要求。
