In the past decade,boron neutron capture therapy utilizing an accelerator-based neutron source(ABNS)designed primarily for producing epithermal neutrons has been implemented in the treatment of brain tumors and other ...In the past decade,boron neutron capture therapy utilizing an accelerator-based neutron source(ABNS)designed primarily for producing epithermal neutrons has been implemented in the treatment of brain tumors and other cancers.The specifications for designing an epithermal beam are primarily based on the IAEA-TECODC-1223 report,issued in 2001 for reactor neutron sources.Based on this report,the latest perspectives and clinical requirements,we designed an ABNS capable of adjusting the average neutron beam energy.The design was based on a 2.8 MeV,20 mA proton beam bombarding a lithium target to produce neutrons that were subsequently moderated and tuned through a tunable beam shaping assembly(BSA)which can modify the thicknesses and materials of the coin-shaped moderators,back reflectors,filters,and collimators.The simulation results demonstrated that epithermal neutron beams for deep seated tumor treatment,which were generated by utilizing magnesium fluoride with lengths ranging between 28 and 36 cm as the moderator,possessed a treatment depth of 5.6 cm although the neutron flux peak shifts from 4.5 to 1.0 keV.When utilizing a thinner moderator,a less accelerated beam power can meet the treatment requirements.However,higher powers reduced the treatment time.In contrast,employing a thick moderator can reduce the skin dose.In scenarios that required relatively low energy neutron beams,the removal of the thermal neutron filter can raise the thermal neutron flux at the beam port.And the depth of the dose rate peak could be adjusted between 0.25 and 2.20 cm by combining magnesium fluoride and polyethylene coins of different thicknesses.Hence,this device has a better adaptability for the treatment of superficial tumors.Overall,the tunable BSA provides greater flexibility for clinical treatment than common BSA designs that can only adjust the port size.展开更多
A new muon beam facility,called the Experimental Muon Source(EMuS),was proposed for construction at the China Spallation Neutron Source(CSNS).The design of the complex muon beamlines for the EMuS baseline scheme,which...A new muon beam facility,called the Experimental Muon Source(EMuS),was proposed for construction at the China Spallation Neutron Source(CSNS).The design of the complex muon beamlines for the EMuS baseline scheme,which is based on superconducting solenoids,superferric dipoles and room-temperature magnets,is presented herein.Various muon beams,including surface muons,decay muons and low energy muons,have been developed for multipurpose applications.The optics design and simulation results of the trunk beamline and branch beamlines are presented.With a proton beam power of 25 kW at a standalone target station that consists of a conical graphite target and high-field superconducting solenoids,the muon beam intensity in the trunk beamline varies from 10^(7)/s for surface muons to 10^(10)/s for high-momentum decay muons.And at the endstations,these values vary from 10^(5)/s for surface muons to 10^(8)/s for decay muons.展开更多
A recent experimental finding replicated an earlier research result, both of which demonstrated conflict with a specific Standard Model prediction. The “Muon g - 2” studies have indicated that the degree of muon pre...A recent experimental finding replicated an earlier research result, both of which demonstrated conflict with a specific Standard Model prediction. The “Muon g - 2” studies have indicated that the degree of muon precession predicted by the Model is not the same as observed. The researchers offer many posteriori atheoretical hypotheses as possible explanations of their findings, but no fundamental theoretical understanding of the near discovery is among them. This article describes both an explication for the unexpected result and describes its underlying mechanism based on an existing cosmological theory, the Probabilistic Spacetime Theory. The paper also discusses the potential value of this theory.展开更多
This study aimed to investigate the relationship between atmospheric conditions and cosmic ray (CR) muons using daily and monthly CR data collected by the KAAU muon detector in Jeddah, Saudi Arabia between 2007 and 20...This study aimed to investigate the relationship between atmospheric conditions and cosmic ray (CR) muons using daily and monthly CR data collected by the KAAU muon detector in Jeddah, Saudi Arabia between 2007 and 2012. Specifically, the study examined the effects of atmospheric pressure, air temperature, and relative humidity on CR muons at different time scales (annual, seasonal, and monthly). The results of the analysis revealed that atmospheric pressure and air temperature had a negative impact on CR muons, while relative humidity had a positive impact. Although air temperature and relative humidity had small mean values across all time scales, their coefficients varied significantly from month to month and season to season. In addition, the study conducted multivariable correlation analyses for each day, which showed that pressure coefficients had consistently negative mean values, while the temperature and humidity coefficients had varying effects, ranging from positive to negative values. The reasons for the variations in the coefficients are not yet fully understood, but the study proposed several possible terrestrial and extraterrestrial explanations. These findings provide important insights into the complex interactions between the Earth’s atmosphere and cosmic rays, which can contribute to a better understanding of the potential impacts of cosmic rays on the Earth’s climate and environment.展开更多
Muon scattering tomography is believed to be a promising technique for cargo container inspection, owing to the ability of natural muons to penetrate into dense materials and the absence of artificial radiation. In th...Muon scattering tomography is believed to be a promising technique for cargo container inspection, owing to the ability of natural muons to penetrate into dense materials and the absence of artificial radiation. In this work, the material discrimination ability of muon scattering tomography is evaluated based on experiments at the Tsinghua University cosmic ray muon tomography facility,with four materials: flour(as drugs substitute), aluminum,steel, and lead. The features of the different materials could be discriminated with cluster analysis and classifiers based on support vector machine. The overall discrimination precisions for these four materials could reach 70, 95, and 99% with 1-, 5-, and 10-min-long measurement,respectively.展开更多
Muon tomography is a capable imaging technique to measure the geometry of high-Z objects. However,most existed algorithms used in muon tomography have obscured the effects of angular distribution and momentum spectra ...Muon tomography is a capable imaging technique to measure the geometry of high-Z objects. However,most existed algorithms used in muon tomography have obscured the effects of angular distribution and momentum spectra of cosmic ray muons and reduced the spatial resolution. We present a modified multi-group model that takes into account these effects and calibrates the model by the material of lead. Performance tests establish that the model is capable of measuring the thickness of a Pb slab and identifying the material of an unknown slab on a reasonable exposure timescale, in both cases of complete and incomplete angular data. Results show that the modified multi-group model is helpful for improvements in image resolution in real applications.展开更多
基金supported by the National Nature Science Foundation of China(No.1210050454)the program of Chinese Scholarship Council(No.202106280126)。
文摘In the past decade,boron neutron capture therapy utilizing an accelerator-based neutron source(ABNS)designed primarily for producing epithermal neutrons has been implemented in the treatment of brain tumors and other cancers.The specifications for designing an epithermal beam are primarily based on the IAEA-TECODC-1223 report,issued in 2001 for reactor neutron sources.Based on this report,the latest perspectives and clinical requirements,we designed an ABNS capable of adjusting the average neutron beam energy.The design was based on a 2.8 MeV,20 mA proton beam bombarding a lithium target to produce neutrons that were subsequently moderated and tuned through a tunable beam shaping assembly(BSA)which can modify the thicknesses and materials of the coin-shaped moderators,back reflectors,filters,and collimators.The simulation results demonstrated that epithermal neutron beams for deep seated tumor treatment,which were generated by utilizing magnesium fluoride with lengths ranging between 28 and 36 cm as the moderator,possessed a treatment depth of 5.6 cm although the neutron flux peak shifts from 4.5 to 1.0 keV.When utilizing a thinner moderator,a less accelerated beam power can meet the treatment requirements.However,higher powers reduced the treatment time.In contrast,employing a thick moderator can reduce the skin dose.In scenarios that required relatively low energy neutron beams,the removal of the thermal neutron filter can raise the thermal neutron flux at the beam port.And the depth of the dose rate peak could be adjusted between 0.25 and 2.20 cm by combining magnesium fluoride and polyethylene coins of different thicknesses.Hence,this device has a better adaptability for the treatment of superficial tumors.Overall,the tunable BSA provides greater flexibility for clinical treatment than common BSA designs that can only adjust the port size.
基金supported by the National Natural Science Foundation of China(Nos.11527811 and 12035017).
文摘A new muon beam facility,called the Experimental Muon Source(EMuS),was proposed for construction at the China Spallation Neutron Source(CSNS).The design of the complex muon beamlines for the EMuS baseline scheme,which is based on superconducting solenoids,superferric dipoles and room-temperature magnets,is presented herein.Various muon beams,including surface muons,decay muons and low energy muons,have been developed for multipurpose applications.The optics design and simulation results of the trunk beamline and branch beamlines are presented.With a proton beam power of 25 kW at a standalone target station that consists of a conical graphite target and high-field superconducting solenoids,the muon beam intensity in the trunk beamline varies from 10^(7)/s for surface muons to 10^(10)/s for high-momentum decay muons.And at the endstations,these values vary from 10^(5)/s for surface muons to 10^(8)/s for decay muons.
文摘A recent experimental finding replicated an earlier research result, both of which demonstrated conflict with a specific Standard Model prediction. The “Muon g - 2” studies have indicated that the degree of muon precession predicted by the Model is not the same as observed. The researchers offer many posteriori atheoretical hypotheses as possible explanations of their findings, but no fundamental theoretical understanding of the near discovery is among them. This article describes both an explication for the unexpected result and describes its underlying mechanism based on an existing cosmological theory, the Probabilistic Spacetime Theory. The paper also discusses the potential value of this theory.
文摘This study aimed to investigate the relationship between atmospheric conditions and cosmic ray (CR) muons using daily and monthly CR data collected by the KAAU muon detector in Jeddah, Saudi Arabia between 2007 and 2012. Specifically, the study examined the effects of atmospheric pressure, air temperature, and relative humidity on CR muons at different time scales (annual, seasonal, and monthly). The results of the analysis revealed that atmospheric pressure and air temperature had a negative impact on CR muons, while relative humidity had a positive impact. Although air temperature and relative humidity had small mean values across all time scales, their coefficients varied significantly from month to month and season to season. In addition, the study conducted multivariable correlation analyses for each day, which showed that pressure coefficients had consistently negative mean values, while the temperature and humidity coefficients had varying effects, ranging from positive to negative values. The reasons for the variations in the coefficients are not yet fully understood, but the study proposed several possible terrestrial and extraterrestrial explanations. These findings provide important insights into the complex interactions between the Earth’s atmosphere and cosmic rays, which can contribute to a better understanding of the potential impacts of cosmic rays on the Earth’s climate and environment.
文摘Muon scattering tomography is believed to be a promising technique for cargo container inspection, owing to the ability of natural muons to penetrate into dense materials and the absence of artificial radiation. In this work, the material discrimination ability of muon scattering tomography is evaluated based on experiments at the Tsinghua University cosmic ray muon tomography facility,with four materials: flour(as drugs substitute), aluminum,steel, and lead. The features of the different materials could be discriminated with cluster analysis and classifiers based on support vector machine. The overall discrimination precisions for these four materials could reach 70, 95, and 99% with 1-, 5-, and 10-min-long measurement,respectively.
基金supported by the Science and Technology Development Foundation of CAEP(No.2015B0103014)the National Natural Science Foundation of China(No.11605163)
文摘Muon tomography is a capable imaging technique to measure the geometry of high-Z objects. However,most existed algorithms used in muon tomography have obscured the effects of angular distribution and momentum spectra of cosmic ray muons and reduced the spatial resolution. We present a modified multi-group model that takes into account these effects and calibrates the model by the material of lead. Performance tests establish that the model is capable of measuring the thickness of a Pb slab and identifying the material of an unknown slab on a reasonable exposure timescale, in both cases of complete and incomplete angular data. Results show that the modified multi-group model is helpful for improvements in image resolution in real applications.