Which Neighborhoods Have Easier Access to Online Home Delivery Services?A Spatiotemporal Accessibility Analysis in Nanjing,China

The rise in online home delivery services(OHDS)has had a significant impact on how urban services are supplied and used in recent years.Studies on the spatial accessibility of OHDS are emerging,but few is known about the temporal dimension of OHDS accessibility as well as the geographic and socioeconomic differences in the spatiotemporal accessibility of OHDS.This study measures the spatiotemporal accessibility of four types of OHDS,namely leisure,fresh and convenient,medical,and catering services.The geographic and socioeconomic disparities in the spatiotemporal accessibility of these four types of OHDS are then identified using spatial statistical methods and the Kruskal-Wallis test(K-W test).The case study in Nanjing,China,suggests that:1)spatiotemporal accessibility better reflects the temporal variation of OHDS accessibility and avoids overestimation of OHDS accessibility when only considering its spatial dimension.2)The spatiotemporal accessibility of OHDS varies geographically and socioeconomically.Neighborhoods located in the main city or neighborhoods with higher housing prices,higher population density,and higher point of interest(POI)mix have better OHDS spatiotemporal accessibility.Our study contributes to the understanding of OHDS accessibility from a spatiotemporal perspective,and the empirical insights can assist policymakers in creating intervention plans that take into account variations in OHDS spatiotemporal accessibility.

Al-modified yolk-shell silica particle-supported NiMo catalysts for ultradeep hydrodesulfurization of dibenzothiophene and 4,6-dimethyldibenzothiophene:Efficient accessibility of active sites and suitable acidity

Yolk-shell SiO2 particles(YP)with center-radial meso-channels were fabricated through a simple and effective method.Al-containing YP-supported NiMo catalysts with different Al amounts(NiMo/AYP-x,x=Si/Al molar proportion)were prepared and dibenzothiophene(DBT)and 4,6-dimethyl-dibenzothiophene(4,6-DMDBT)were employed as the probes to evaluate the hydrodesulfurization(HDS)catalytic performance.The as-prepared AYP-x carriers and corresponding catalysts were characterized by some advanced characterizations to obtain deeper correlations between physicochemical properties and the HDS performance.The average pore sizes of series AYP-x supports are above 6.0 nm,which favors the mass transfer of organic sulfides.The cavity between the yolk and the shell is beneficial for the enrichment of S-containing compounds and the accessibility between reactants and active metals.Aluminum embedded into the silica framework could facilitate the formation of Lewis(L)and Brønsted(B)acid sites and adjust the metal-support interaction(MSI).Among all the as-synthesized catalysts,NiMo/AYP-20 catalyst shows the highest HDS activities.The improved HDS activity of NiMo/AYP-20 catalyst is attributed to the perfect combination of excellent structural properties of the yolk-shell mesoporous silica,enhanced acidity,moderate MSI,and good accessibility/dispersion of active components.

Influence of Transportation Accessibility on Urban-rural Income Disparity and Its Spatial Heterogeneity

Transportation accessibility has been treated as an important means of reducing the urban-rural income disparity.However,only a few studies have examined the effects of different types of transportation accessibility on urban-rural income disparity and their spatial heterogeneity.Based on data from 285 prefecture-level(and above)Chinese cities in 2000,2005,2010,2015,and 2020,this study uses spatial econometric models to examine how highway accessibility and railway accessibility influence the urban-rural income disparity and to identify their spatial heterogeneity.The result reveals that highway accessibility and railway accessibility have‘coreperiphery’ring-like circle structures.The urban-rural income disparity exhibits strong spatial clustering effects.Both highway accessibility and railway accessibility are negatively associated with urban-rural income disparity,and the former having a greater effect size.Moreover,there is a substitution effect between highway accessibility and railway accessibility in the whole sample.Furthermore,these associations differ in geographic regions.In the central region,highway accessibility is more important in reducing the urban-rural income disparity,but its effect is weakened with the increase of railway accessibility.In the western region,railway accessibility has a larger effect on narrowing the urban-rural income disparity,and this effect is strengthened by the increase of highway accessibility.We conclude that improving transportation accessibility is conducive to reducing the urban-rural income disparity but its effect is spatial heterogenetic.Highways and railways should be developed in a coordinated manner to promote an integrated transport network system.

Mapping and measuring urban-rural inequalities in accessibility to social infrastructures

Equal access to social infrastructures is a fundamental prerequisite for sustainable development,but has long been a great challenge worldwide.Previous studies have primarily focused on the accessibility to social infras-tructures in urban areas across various scales,with less attention to rural areas,where inequality can be more severe.Particularly,few have investigated the disparities of accessibility to social infrastructures between urban and rural areas.Here,using the Changsha-Zhuzhou-Xiangtan urban agglomeration,China,as an example,we investigated the inequality of accessibility in both urban and rural areas,and further compared the urban-rural difference.Accessibility was measured by travel time of residents to infrastructures.We selected four types of social infrastructures including supermarkets,bus stops,primary schools,and health care,which were funda-mentally important to both urban and rural residents.We found large disparities in accessibility between urban and rural areas,ranging from 20 min to 2 h.Rural residents had to spend one to two more hours to bus stops than urban residents,and 20 min more to the other three types of infrastructures.Furthermore,accessibility to multiple infrastructures showed greater urban-rural differences.Rural residents in more than half of the towns had no access to any infrastructure within 15 min,while more than 60%of the urban residents could access to all infrastructures within 15 min.Our results revealed quantitative accessibility gap between urban and rural areas and underscored the necessity of social infrastructures planning to address such disparities.

Accessibility and Fairness of Public Service Facilities from the Perspective of Supply and Demand Coordination: A Case Study of Old Urban Area of Guangzhou City

The accessibility and fairness of public service facilities are important manifestations of the convenience and equality of urban public service resource allocation.Optimizing the layout of urban public service facilities is an inevitable requirement for promoting the construction of people centered cities.This paper takes the old urban area of Guangzhou as the research area,measures the accessibility of multiple types of public service facilities based on an improved two-step floating catchment method,and combines Palma Ratio and location quotient methods to explore the fairness of urban public service facilities from two dimensions:social equity and spatial equity,with supply and demand relationship analysis as the main line.Research has shown that:①there is a significant spatial difference in the accessibility of public service facilities in the old urban areas of Guangzhou,and the comprehensive accessibility is generally higher in the central and southeastern regions of the old urban areas with fewer residential populations;②from the perspective of social equity,the resource allocation of public service facilities in the old urban areas of Guangzhou is in a seriously unfair state(with a fairness index of 2.99),and there are also varying degrees of unfairness within the streets;③from the perspective of spatial equity,the location quotient of public service facilities in the old urban areas of Guangzhou shows a pattern of multil center circles decreasing,indicating a significant spatial mismatch between the accessibility supply side of public service facilities and the demand side of the residential population.The research conclusion will provide scientific basis for optimizing the allocation of urban public service facilities and ensuring the equalization of public services.

Prevalence of Occupational Injury and Knowledge of Post-Exposure Prophylaxis Accessibility among Healthcare Workers in Mogadishu, Somalia

Introduction: Healthcare workers in Mogadishu, Somalia face significant occupational injury risks, particularly needle stick injuries, with 61.1% reporting incidents. This poses a serious threat to their health, leading to infections such as hepatitis B, hepatitis C, and HIV. Despite the high prevalence of injuries, awareness of Post-Exposure Prophylaxis (PEP) accessibility is relatively high, with 84.0% of respondents aware of it. However, there are gaps in knowledge and implementation, as evidenced by variations in availability of PEP. Improving workplace safety measures, providing comprehensive training on injury prevention and PEP protocols, and ensuring consistent availability of PEP in healthcare facilities are crucial steps to safeguard the well-being of healthcare workers in Mogadishu, Somalia. Methods: A cross-sectional study was conducted among hospital workers in Mogadishu, Somalia, focusing on professionals from various healthcare facilities. The study targeted nurses, doctors, laboratory personnel, and pharmacists. Purposive sampling was employed, resulting in a sample size of 383 calculated using Fisher’s sample size formula. Data were collected using coded questionnaires entered into Microsoft Excel 2019 and analyzed with SPSS software to generate frequencies and proportions, presented through frequency tables and pie figures. Results: The study in Mogadishu, Somalia, examined the prevalence of occupational injuries and knowledge of Post-Exposure Prophylaxis (PEP) accessibility among healthcare workers. Findings indicate a high prevalence of injuries, with 61.1% reporting incidents, predominantly needle stick injuries (60.6%). Despite the majority seeking prompt medical attention (72.0%), work-related illnesses affected 53.2% of respondents, notably work-related stress (59.5%). While most received training on injury and illness prevention (68.9%), gaps exist in PEP awareness, with 16.0% unaware of it. Nonetheless, 84.0% were aware, predominantly through health facilities (52.0%). Availability of PEP was reported by 71.3% in healthcare facilities, with variations in shift availability. The majority reported guidelines for PEP use (55.7%). Efforts are needed to bolster PEP awareness and ensure consistent availability in healthcare facilities to safeguard worker health. Conclusion: High prevalence of occupational injuries among healthcare workers, with needle stick injuries being the most common (60.6%). Despite this, 84.0% of respondents were aware of Post-Exposure Prophylaxis (PEP), primarily learning about it from health facilities (52.0%). While 71.3% reported the availability of PEP in their facility, 28.7% noted its unavailability. These results emphasize the need for improved education and accessibility of PEP to mitigate occupational injury risks.

Affordability, Accessibility, and Quality of Maternal Health Care Services and Level of Satisfaction of Mothers in Rural Areas in China

Objective:This study aimed to understand the affordability,accessibility,and quality of maternal and child health services for postpartum mothers,and their impact on satisfaction.Methods:The study utilized the Anderson model and revised the Maternal Pregnancy and Perinatal Health Service Questionnaire.A survey was conducted among 289 mothers aged 20–49 in Feicheng City.Results:Regarding accessibility,most respondents(133)reported that travel time to healthcare services exceeded 60 minutes,while 99 respondents indicated a travel time of 16–30 minutes.The issue of affordability was highlighted,with 86.85%of participants perceiving maternal healthcare services as costly,indicating a significant financial burden.More than 50%of respondents were satisfied with two specific dimensions(P<0.05)regarding the quality of maternal healthcare services.Conclusion:The study found that accessibility,affordability,and quality significantly affect mothers’satisfaction with maternal health services.Future research should focus on developing more suitable service pathways for rural mothers.

Study on the Influence of Lanzhou-Urumqi High-Speed Railway on Regional Accessibility and Economic Development

The Lanzhou-Urumqi high-speed railway is an important part of the railway network connecting Gansu,Qinghai,and Xinjiang,and it is of far-reaching significance in facilitating China’s western development.An accessibility model and a double difference model were built to analyze the impact of the Lanzhou-Urumqi high-speed railway on regional accessibility and economic development of the areas along the line before(2012-2014)and after(2017-2019)its opening.The results show that the regional accessibility remains unchanged before and after the operation of this railway line.However,there is a spatial difference in improvement,that of central cities being better.The opening of the high-speed railway is conducive to driving the overall economic development of the region and promoting the comprehensive and coordinated development of regional economies.

Accessibility and utilization of healthcare services among diabetic patients:Is diabetes a poor man’s ailment?

Diabetes is a non-communicable ailment that has adverse effects on the individual’s overall well-being and productivity in society.The main objective of this study was to examine the empirical literature concerning the association between diabetes and poverty and the accessibility and utilization of medical care services among diabetic patients.The diabetes literature was explored using a literature review approach.This review revealed that diabetes is an ailment that affects all individuals irrespective of socioeconomic status;however,its prevalence is high in low-income countries.Hence,despite the higher prevalence of diabetes in developing countries compared with developed countries,diabetes is not a poor man’s ailment because it affects individuals of all incomes.While the number of diabetic patients that access and utilize diabetes medical care services has increased over the years,some personal and institutional factors still limit patients’access to the use of diabetes care.Also,there is a lacuna in the diabetes literature concerning the extent of utilization of available healthcare services by diabetic patients.

GIS-Based Analysis to Identify the Distribution and Accessibility of Urban Green Space in Dhaka Metropolitan City, Bangladesh

Urban Green Space (UGS) plays an important role in minimizing the negative effects of urbanization on city dwellers, which is predominantly factored into the accessibility to UGS. This study elucidated the distribution and accessibility of UGS in Dhaka, Bangladesh considering the paucity of such important scientific studies in the given area. The methodological structure of this study employed a multispectral Landsat satellite image from 2020 for identifying the logically defined UGSs, as well as a minimum proxy distance being the parameter to estimate accessibility to the UGS through a primary survey scheme and literature review. Considering UGS as a public area, we adopted a hybrid (combination of supervised and unsupervised classification) method followed by post-classification for UGS distribution assessment. The unsupervised classification identified the overall distribution of green spaces, whereas the anomalies of generated classes were rectified during the post-classification. Following the study findings, UGS in Dhaka metropolitan city accounts for only 602 ha or 1.9% of the total geographical space, with Ramna thana ranked as the highest contributor of 111 ha. However, in terms of accessibility to the UGS by city residents, 19.9% of the buildings in Dhaka metropolitan city were computed to be within the determined proxy distance of 500 m around the UGS. Also, parallel to UGS distribution, green space in Ramna thana (111 ha) exhibited the highest accessibility rate (64%) to the UGS compared with other thanas in Dhaka metropolitan city. The baseline findings will contribute to the long-term sustainable urban planning and development of more accessible green spaces in the study area.

Dek219 encodes the DICER-LIKE1 protein that affects chromatin accessibility and kernel development in maize

Chromatin accessibility plays a vital role in gene transcriptional regulation.However,the regulatory mechanism of chromatin accessibility,as well as its role in regulating crucial gene expression and kernel development in maize(Zea mays)are poorly understood.In this study,we isolated a maize kernel mutant designated as defective kernel219(dek219),which displays opaque endosperm and embryo abortion.Dek219 encodes the DICER-LIKE1(DCL1)protein,an essential enzyme in mi RNA biogenesis.Loss of function of Dek219 results in significant reductions in the expression levels of most mi RNAs and histone genes.Further research showed that the Heat shock transcription factor17(Hsf17)-Zm00001d016571 module may be one of the factors affecting the expression of histone genes.Assay results for transposase-accessible chromatin sequencing(ATAC-seq)indicated that the chromatin accessibility of dek219 is altered compared with that of wild type(WT),which may regulate the expression of crucial genes in kernel development.By analyzing differentially expressed genes(DEGs)and differentially accessible chromatin regions(ACRs)between WT and dek219,we identified 119 candidate genes that are regulated by chromatin accessibility,including some reported to be crucial genes for kernel development.Taken together,these results suggest that Dek219 affects chromatin accessibility and the expression of crucial genes that are required for maize kernel development.

Chicken chromatin accessibility atlas accelerates epigenetic annotation of birds and gene fine-mapping associated with growth traits

The development of epigenetic maps, such as the ENCODE project in humans, provides resources for gene regulation studies and a reference for research of disease-related regulatory elements. However,epigenetic information, such as a bird-specific chromatin accessibility atlas, is currently lacking for the thousands of bird species currently described.The major genomic difference between birds and mammals is their shorter introns and intergenic distances, which seriously hinders the use of humans and mice as a reference for studying the function of important regulatory regions in birds. In this study, using chicken as a model bird species, we systematically compiled a chicken chromatin accessibility atlas using 53 Assay of Transposase Accessible Chromatin sequencing(ATAC-seq)samples across 11 tissues. An average of 50 ?796open chromatin regions were identified per sample,cumulatively accounting for 20.36% of the chicken genome. Tissue specificity was largely reflected by differences in intergenic and intronic peaks, with specific functional regulation achieved by two mechanisms: recruitment of several sequence-specific transcription factors and direct regulation of adjacent functional genes. By integrating data from genome-wide association studies, our results suggest that chicken body weight is driven by different regulatory variants active in growth-relevant tissues. We propose CAB39L(active in the duodenum), RCBTB1(muscle and liver), and novel long non-coding RNA ENSGALG00000053256(bone) as candidate genes regulating chicken body weight. Overall, this study demonstrates the value of epigenetic data in fine-mapping functional variants and provides a compendium of resources for further research on the epigenetics and evolution of birds and mammals.

Using ArcGIS to Study Transportation Accessibility of Cultural Tourism Resources with Wan'an County in Jiangxi Province as an Example

This paper reviews cultural tourist attractions and transportation conditions of Wan'an County in Jiangxi Province,and calculates the accessibility and kernel density of transportation network by using ArcGIS.Through the analysis,it obtains the spatial relationship between the accessibility of Wan an County and the spatial structural characteristics of"one center,two clusters,two verticals and one horizontal"presented by the cultural tourism resources.Based on this,the paper puts forward the transportation development suggestions for the development of cultural tourism for Wan'an County.

Geostatistical Analysis of Accessibility to Secondary Schools in Parts of Benue State

This research studied accessibility to secondary schools in some parts of Benue State. The objective of the study was to determine the level of accessibility to secondary school. The study adopted survey, field observation and measurement to obtain the needed data. The study adopted gravity model as the related theoretical framework. GIS and descriptive statistical techniques were employed to map, visualize and analyze the data. The result shows that accessibility to secondary school in the three Local Government Areas is generally low, though it varies between schools, within and between Local Government Areas. This depicts a very stressful schooling condition for the majority of students, and has far-reaching implications in terms of lack of skilled manpower, inadequate facilities and consequently low standards in the educational system. To ensure effective and valid decision-making, and maintain high standards in the system, it was recommended that equitable and systematic distribution of school facilities should be embraced. Furthermore, more schools should be established in the areas which currently have low accessibility to bridge the accessibility gap and encourage active participation and consistent attendance at schools among the students.

Spatial Accessibility of Emergency Facilities to Road Accident Victims in Federal Capital City

This paper studied the spatial accessibility of emergency facilities to road accident victims in Federal Capital City to determine the sufficiency of existing emergency health care facilities and rescue facilities in servicing accident victims. This is useful for developing means of saving the lives of accident victims in the Federal Fapital City (FCC). The data used comprised of Nigerian Sat II 2013 multispectral imagery (5 m multispectral and 2.5 m Panchromatic) of FCC obtained from the National Space Research and Development Agency (NARSDA), coordinates of seventy (70) accident black spots, five (5) zebra points and sixteen (16) emergency health care facilities obtained from Federal Road Safety Commission (FRSC). ArcGIS 10.0 software was used to display, visualize, identify and extract features from the imagery, and create maps from different layers of the spatial data, choose colors and symbols, create buffer zones, analyze spatial relationships, and design map layouts. Purposeful sampling method was adopted to administer 99 questionnaires to accident victims in the hospitals within the FCC. The spatial data were used to determine the time of rescue, type of rescue and coverage time of rescue operation. The statistical data were used to assess the spatio-temporal distribution of accidents and determine the level of response by the rescue teams. The results show that accident victims have adequate access to health facilities but inadequate access to zebra points, and passers-by have more effective accident response than the government action agencies. Specific points for the creation of additional zebra points were identified through buffering, and the creation of sustainable Good Samaritan programs and training for community persons in first aid were suggested. Meanwhile, further research to determine the impact of time of rescue, type of rescue and category of hospital on the accident victims was suggested.

Accessibility Measures in Modal Choice Models: A Proof of Concept Applied to Freight Transport

Modal choice models applied to interregional or international freight transportation network models are often based on rather coarse origin-destination matrices, containing annual transported tonnages between (sub)regions, for instance. Generally, only basic (sometimes constructed) independent variables (transportation costs or transit times) are used because other variables such as shipment sizes, service frequencies, etc. are not available. Using origin-destination matrices and an assignment model, it is also possible to compute spatial accessibility measures that can further be used as additional explanatory variables. Indeed, several published studies have identified network accessibility as an important element in the mode-choice decision. This paper also shows that the inclusion of an accessibility measure in the utility functions of a logit model substantially improves the performance of a transportation network model, both in the modal choice and the assignment levels of the classical four-step model. Consequently, the assignment of the estimated modal demands results in more accurate estimated traffic on the networks. The model presented in this paper is to be considered as a proof of concept because its workflow should further be streamlined to make it easily useable by modelers.

Urban Accessibility in Motorcycle Dependent Cities - Case Study in Ho Chi Minh City, Vietnam

Motorcycle dependent cities have specific characteristics in terms of urban accessibility.A rapid increase in the number of motorcycles and other private motorized modes make transport problems more serious and cause severe capacity problems for the infrastructure systems in these cities.Therefore,it is necessary to optimize the development of different modes to meet travel demand and to ensure accessibility in all urban areas.This paper aims to explore accessibility conditions in Ho Chi Minh City,a typical motorcycle dependent city in Vietnam.Understanding of accessibility could be the key element for urban planning in Ho Chi Minh City in particular and motorcycle dependent cities in general.Then,management measures for motorcycles and competitive modes will be proposed to improve the accessibility conditions and thus support sustainable urban transport development for motorcycle dependent cities.

4例儿童植入式静脉输液港导管断裂原因分析及处理

目的探讨4例儿童植入式静脉输液港导管发生断裂的原因,并总结护理经验。方法2011年3月—2023年1月本科室共植入应用输液港319例,其中4例患儿发生导管断裂,发生率1.3%,4例患儿断裂的输液港均经手术完整取出;对导管发生断裂的原因、识别方法进行分析总结。结果病例1导管断裂位置距离港座6cm,断裂的导管未发生移位;病例2在距离港座7cm处发现导管呈线状裂纹,外观完整无断裂,推注液体时可见裂纹处有液体溢出;病例3导管断裂位置距离港座11cm,断裂的导管未发生移位;病例4导管断裂位置距离港座1cm处,且断裂后导管沿右心房-右肺动脉-右下肺动脉发生移位。输液港导管断裂原因:病例1、3、4有频繁且长时间的颈部、上肢肢体活动;病例2输液港维护不当。输液港拔除术后,病例1、2、4患儿因原发病需继续住院治疗,病例3术后第2天出院。结论导管断裂是输液港临床维护及使用过程中的严重并发症之一,医护人员应重视输液港规范化操作与维护、加强患儿及家长的健康宣教,及时发现异常并处理,其是保障患儿输液港安全使用的重要措施。

元宇宙赋能公共图书馆无障碍服务:壁垒突破、体系构建与路径探究

公共图书馆无障碍服务致力于帮助残障人士等特殊群体享受公共文化服务、共享数字生活,是无障碍环境建设的一部分。元宇宙为公共图书馆无障碍服务提供了新思路,注入了新活力。文章通过阐述公共图书馆无障碍服务在互联网不同阶段的发展与变化,总结元宇宙赋能公共图书馆无障碍服务实现的壁垒突破,构建无障碍服务体系,探究推进路径。公共图书馆无障碍服务建设应多点突破,以用户需求为主导,提供更便捷的均等化服务,在元宇宙相关技术加持下弥合数字鸿沟,促进社会包容。

下行RIS-NOMA的用户集群方法

为提高用户分布非均匀的场景下可重构智能表面(RIS)辅助下行非正交多址(NOMA)通信系统的性能,提出了一种分布式RIS辅助下行NOMA的用户聚类方案。首先,采用自适应几何分布(AGD)聚类算法划分用户集群(UCs),从而为各UC匹配RIS。然后,利用分式规划(FP)方法将非凸最大化频谱效率问题转换为凸优化问题。最后,为UC内用户逐级进行功率分配(PA)与被动波束形成(PB)。仿真结果表明,与谱聚类(SPC)、K均值(K-means)、高斯混合模型(GMM)聚类方案和正交多址(OMA)方案相比,在AGD方案下,功率对频谱效率提升了7%、14%、19%和42%的增益,反射面对频谱效率提升了16%、19%、26%和40%的增益。