Biological activity dressings on wound healing consist of Prionace glauca cartilage type Ⅱ collagen( CII) cartilage,chitosan and polyethylene oxide( PEO). The dressing fibers are successfully obtained by electrospinn...Biological activity dressings on wound healing consist of Prionace glauca cartilage type Ⅱ collagen( CII) cartilage,chitosan and polyethylene oxide( PEO). The dressing fibers are successfully obtained by electrospinning from the acetic acid aqueous solution( 80%, volume fraction). An effective quadric polynomial regression model,including the feed speed( m L/h),the applied voltage( kV) and the nozzle-collector distance( cm),was set up by response surface methodology. By using the optimized process parameters( applied voltage 20 kV,nozzle-collector distance 16. 6 cm and feed speed 0. 70 m L/h),the mean diameter( 230. 34 nm) was reduced by about 10% compared with the original one.展开更多
基金National Science and Technology Major Project of the Ministry of Science and Technology of China(No.2014ZX09J14103-09C-003)
文摘Biological activity dressings on wound healing consist of Prionace glauca cartilage type Ⅱ collagen( CII) cartilage,chitosan and polyethylene oxide( PEO). The dressing fibers are successfully obtained by electrospinning from the acetic acid aqueous solution( 80%, volume fraction). An effective quadric polynomial regression model,including the feed speed( m L/h),the applied voltage( kV) and the nozzle-collector distance( cm),was set up by response surface methodology. By using the optimized process parameters( applied voltage 20 kV,nozzle-collector distance 16. 6 cm and feed speed 0. 70 m L/h),the mean diameter( 230. 34 nm) was reduced by about 10% compared with the original one.
