Research on law of acupoints selection for acupuncture treatment of postpartum depression based on data mining method

Objective:To obtain the rules of acupoint use and compatibility methods from RCT literature of acupunctureand moxibustion in the treatment of postpartum depression through data mining,so as to provide effective acupoints for clinical reference.Methods:a total of 557 clinical literatures on acupuncture and moxibustion in the treatment of postpartum depression were retrieved through China knowledge Network Database,Wanfang Database and Chongqing VIP Database,and 44 articles were obtained through inclusion and exclusion criteria.Statistical analysis was carried out with the help of SPSS20.0 and SPSS Modeler18.1.Results:the most commonly used acupuncture points for postpartum depression are Baihui,Taichong,Sanyinjiao,Zusanli,Neiguan,Governor Meridian,foot Jueyin liver Meridian and foot Sun bladder Meridian,which are closely related to the treatment of postpartum depression.most doctors'clinical acupuncture treatment sites are head,limbs and back.The correlation analysis results obtained by SPSS Modeler software are Taichong-Neiguan-Zusanli,Taichong-Neiguan and Neiguan-Zusanli.Finally,the high-frequency acupoints are clustered and classified into four clusters,namely Taichong,Neiguan,Sanyinjiao and Zusanli.Hegu,Sishencong;Baihui,Shenmen;Pishu and Guanyuan.Conclusion:the rule of acupoint use of acupuncture and moxibustion in the treatment of postpartum depression through data mining can provide some reference for the clinical treatment of postpartum depression in the future.

The research on rule of Acupoints and Massage Manipulations selection for Post-ischemic Stroke Constipation based on association rule and entropy clustering analysis

Constipation is a common complication of stroke,and it is increasing year by year,which is worthy of attention.In fact,as an effective treatment for Post-ischemic Stroke Constipation,massage has been recognized by doctors at home and abroad.However,In the known research reports,massage prescriptions are complicated,therefore,a simple and effective massage prescription is urgently needed to effectively guide the clinic and promote it.In this study,we used association rule and entropy clustering analysis methods to mine clinical literature on Post-ischemic Stroke Constipation in 7 databases,and combined with data analysis,traditional chinese massage theory and clinical practice,a core new prescription is summarized.The core new prescription of massage in treating Post-ischemic Stroke Constipation take tonifying spleen,nourishing Qi and generating Body Fluid,promoting Qi,invigorating the circulation of blood and eliminating phlegm as the principle of treatment,which is accord with the pathogenesis of this disease,can better guide the clinical practice and facilitate the popularization and application of massage therapy.

Mechanism of Scalp Acupuncture Combined with Distal Acupoint Selection in the Treatment of Vascular Headache Caused by Hyperactivity of Liver-Yang

The clinical effect of acupuncture on vascular headache caused by hyperactivity of liver-yang has been shown, but the specific mechanism is not yet clear. This paper is intended to discuss the etiology and pathogenesis of vascular headache caused by hyperactivity of liver-yang and the mechanism of acupuncture, so as to provide a certain reference for clinical diagnosis and treatment of scalp acupuncture treatment of vascular headache caused by hyperactivity of liver-yang.

Comparison of clinical efficacy of neddle knife at acupoints selected from recent regions along meridians and according to anatomical structures in treating early and middle stage knee osteoarthritis

Objective:To stimulate tenderness points around knee joint in two metholds-corresponding acupoints selected from recent regions along meridians and anatomical structures,to compare the clinical efficacy of neddle knife of to cure early and middle stage knee osteoarthritis.Method:70 patients were randomly(Random Number Tables)divided into test group(acupoints selected from recent regions along meridians,n=35)and control group(anatomical structures,n=35),who were diagnosed as knee osteoarthritis.Observe the VAS(visual analogue scale),Lysholm,WOMAC(the Western Ontario and McMaster Unive rsities Osteoarthritis Index)and ROM(rang of motion)between two groups in first week,first month,third month after treatment.Recording the degree of improvement of knee joint’s pain,dysfunction and symptoms of osteoarthritis and rang of motion.Results:Within groups,the VAS,Lysholm,WOMAC and ROM were obviously different from pre-therapy scores in the third,sixth and twelfth week post-therapy(P<0.05).Between groups no significant difference were observed in the third week post-therapy about VAS,Lysholm,WOMAC scores(P>0.05).However,there were differences in the sixth,twelfth weeks post-therapy(P<0.05);compared with control group,the ROM of test group were difference in the third,sixth,twelfth weeks post-therapy(P<0.05).Conclusion:The clinical efficacy of stimulating corresponding acupoints tenderness points selected from recent regions along meridians to treat early and middle stage knee osteoarthritis was superior to anatomical structures,which can effectively relieve pain,dysfunction,symptoms of osteoarthritis of knee joint and rang of motion.

Acupoint selection rules for acupoint application in lung diseases in the post-epidemic era

Objective:To summarize the rules of acupoint selection of acupoint application to prevent and treat lung diseases under the background the post-epidemic era using data-mining technology.Method:The CNKI,Wanfang database,and VIP database were searched for clinical study articles on lung diseases treated by acupoint application published in the past 5 years.Data-eligible papers were extracted to establish a database of acupoint application for lung disease using Microsoft Excel 2019,with the goal of analyzing the frequency of acupoints,acupoint-meridian association,acupoint-location association,specific acupoint frequency,and cluster analysis.Association rules,consisting of acupoints with an application frequency of≥10,were devised by the Apriori algorithm to explore the correlation between acupoint groups and to analyze the rules of the compatibility of acupoint prescriptions.Results:A total of 229 eligible papers met our inclusion criteria.Forty-seven acupoints were applied,for a total frequency of acupoints of 1,035 times.Among these,acupoints for lung diseases were primarily distributed in the back-and-waist and chest-and-abdomen areas.From the analysis of the association rules,we obtained four groups of acupoint association rules based on acupoint clusters with a frequency≥10 and found that Feishu(BL 13),Tiantu(CV 22),Dazhui(GV 14),Dingchuan(EX-B1),and Danzhong(CV 17)constitute the core acupoints of prescriptions for clinical acupoint application to prevent and treat lung diseases.Conclusion:It is clearly shown that the core acupoints are relatively concentrated and that the selected acupoints were mainly locally selected,which could be a matching reference for the long-term prevention and treatment of lung diseases,including COVID-19.

THEORY OF OPPOSITE ACUPOINTS AND ITS CLINICAL APPLICATION

In the light of the position character, acupoints situating on the corresponding medial and lateral sides of the limbs or in the front and back parts of the body trunk are called as “opposite acupoints”. In the present paper, the author expounds its theoretical basis from yin-yang theory, investigates its origin from the location of acupoints and ancient clinical application, and introduces its current application in clinical practice. In addition, the author lists 4 typical cases about treatment of hysteric convulsion, pregnant hypertension, child bed-wetting and leucorrhagia with opposite acupoints. Clinical practice demonstrates that opposite acupoints therapy is fewer in taking acupoints for one session of treatment, simple in operation, and good in the therapeutic effect for treatment of various diseases of different systems in the human body.

Acupoint Selection Standards of Auricular Therapy in the Treatment of Maintenance Hemodialysis Insomnia Based on Data Mining

Background:Insomnia is a high-incidence complication in patients undergoing maintenance hemodialysis(MHD).Auricular therapy can effectively improve sleep with few adverse effects.Acupoint selection affects the impact of auricular therapy.However,there is currently a lack of analysis on the standards of acupoint selection.Our study used data mining technology to investigate the acupoint selection principles and characteristics of auricular therapy for the treatment of MHD-related insomnia.Objective:The objective of the study is to explore the standards of acupoint selection in auricular therapy for the treatment of MHD-related insomnia through data mining technology.Materials and Methods:We searched three English(PubMed,WOS,and Embase)and four Chinese(CNKI,VIP,Wangfang,and CBM)databases for studies on auricular therapy for MHD-related insomnia from self-establishment to November 14,2022.Results:Eighty-one publications were involved,which included 33 acupoints.The most common auricular points in patients with MHD-related insomnia were the Shenmen,heart,and kidney points.More applications involved the visceral,nervous system,and specific acupoints.Five effective clusters and two clusters were obtained through cluster analysis,including specific auricular points for insomnia,such as the multi-dream area,neurasthenia area,deep sleep point,and anterior ear lobe.Complex network analysis showed that the core auricular acupoint combinations for the intervention of MHD-related insomnia were Shenmen with kidney,Shenmen with heart,heart with kidney,heart with Shenmen,and heart and Shenmen with subcortex.Conclusions:The selection of auricular points for the treatment of MHD-related insomnia was guided by the heart theory of traditional Chinese medicine.Clinical treatment attaches importance to the use of the multi-dream area,neurasthenia area,and other acupoints.

DEVELOPMENT OF CLINICAL STUDIES ON ACUPUNCTURE TREATMENT OF SHOULDER PAIN IN PATIENTS WITH WIND STROKE

In the present paper, the authors review some new results of acupuncture treatment of shoulder pain in stroke patients from ① application of filiform needle with different needling manipulations, ② selection and combination of acupoints, and ③ some special needling methods including point-injection. Generally, if acupuncture therapy is used in combination with other rehabilitation methods, the therapeutic effect of shoulder-pain-relief will be much better. Regarding the acupoint selection, both local acupoints and those of the yang meridians are primarily used in clinical practice. Further studies on treating shoulder pain of hemiplegia based upon the basic theory of TCM are necessary.

OBSERVATION ON TREATMENT OF SCIATICA WITH HOUDING ACUPOINT

In the present paper, the author reports the results of acupuncture of Houding (GV 19) and other acupoints selected along the meridian for treating sciatica. A total of 92 sciatica patients were randomly divided into Houding group (n=62) and control group (n=30). In Houding group, patients were treated mainly with puncturing Houding (GV 19), combined with Huantiao (GB 30) when necessary. In control group, patients were treated with Huantiao (GB 30), Yanglingquan (GB 34) or Zhibian (BL 54), Weizhong (BL 40), Chengshan (BL 57), Kunlun (BL 60), etc. which were selected along the route of meridian. Results indicated that following 10 sessions of treatment, in Houing and control groups, of the 62 and 30 cases, 44 and 15 were basically cured, 18 and 10 were improved, 0 and 5 failed in the treatment, with the total effective rates being 100% and 83,3% respectively. The therapeutic effect of Houding (GV 19) is significantly superior to that of acupoints selected along the meridian.

COMMENTS ON THE STUDY OF ACUPOINT COMBINATION AND REMEDIES FOR TREATMENT OF DIABETES MELLITUS WITH ACUPUNCTURE AND MOXIBUSTION

In the present paper, the author reviews the progresses in the study on acumoxi (acupuncture-moxi-bustion) treatment of diabetes mellitus (DM) from Chinese ancient classical works, Chinese and foreign journals. The therapeutic results reveal that acupuncture treatment of DM is effective in improving DM patients' symptoms via vagal-nerve reflex, regulation of neuroendocrine and immune functions. The author holds that ① correct selection of acupoints in accordance with syndrome differentiation and the related meridians and combined application of acupuncture and Chinese herbal medicines (for oral administration) are the key points for raising the therapeutic effect; and ② acupoint combination and curative methods need to be researched further.

A preliminary discussion on rules of clinical acupoint selection of acupuncture for the treatment of chemotherapy-induced nausea and vomiting

Objective To preliminarily investigate the rules of acupoint selection of acupuncture and moxibustion for the treatment of chemotherapy-induced nausea and vomiting by retrospecting pertinent literature from 1986 to 2013. Methods Literature of clinical studies on acupuncture and moxibustion for the treatment of chemotherapy-induced nausea and vomiting published from 1986 to 2013 in CNKI, Wanfang and VlP databases and in PubMed database were retrieved. Data were analyzed statistically via Excel. Results One hundred and nineteen articles retrieved were related to the study. Based on the current literature analysis, meridians selected for acupuncture and moxibustion on chemotherapy-induced nausea and vomiting were mainly the stomach meridian, the pericardium meridian, the conception vessel, the spleen meridian and bladder meridian; point combination was applied more in prescription, accounting for 73.11%, while single point was applied less, only accounting for 26.89%. There were numerous methods for point combinations, but proximal and distal point combination was the most widely used method, accounting for 20.93%. Meanwhile, main acupoints selected were mostly Zusanli （足三里 ST 36）, Neiguan （内关 PC 6）, Zhongwan （中脘CV12）, Gongsun （公孙SP 4） and Taichong （太冲 LR 3） and point combinations were mainly Shenmen （神门 HT 7）, Geshu （膈俞 BL 17）, PishB （脾俞 BL 20）, Weishu （胃俞 BL 21） and Jianli （建里 CV 11）. Conclusion Acupoints selection on acupuncture and moxibustion for chemotherapy-induced nausea and vomiting shows a certain rules that the meridians selected are mainly stomach meridian, pericardium meridian and conception vessel and acupuncture points selected are normally ST 36, PC 6 and CV 12, proximal and distal point combination is applied more, while single point applied less.

灸法用于癌症治疗的选穴规律分析

Objective:To summarize the rules of acupoint selection in treatment of cancer with moxibustion by analyzing the articles of relevant clinical trials in recent years in China,so as to provide the references for acupoint selection of moxibustion for cancer.Methods:The articles of clinical trials for treatment of cancer with moxibustion were retrieved from China National knowledge Infrastructure(CNKI),VIP Chinese Journal Service Platform(VIP)and Wanfang Data Knowledge Service Platform(Wanfang)from 1st January 2015 to 30th June 2021.Using EpiData software,the data were extracted and exported in Excel.The analysis was performed with IBM SPSS Statistics 23 software.Results:A total of 516 articles were collected,including 533 prescriptions with 164 acupoints involved.The high-frequency acupoints were similar among 7 types of cancers and these acupoints mostly acted on supporting the antipathogenic qi,replenishing qi and regulating the spleen and stomach.Regarding meridian tropism,the acupoints from the conception vessel,the governor vessel and bladder meridian were dominant in treatment of cancer with moxibustion.In terms of location distribution,the selected acupoints were generally distributed on the chest,abdomen,lumbar region and the upper back of the body.Based on cancer related symtomes in different systems,the use frequency of Zusanli(ST36)was the highest for the symptoms of the immune,digestive,circulatory and motor systems;that of Feishu(BL13)was the highest for the respiratory system symptoms and that of Guanyuan(CV4)was the highest for the urinary system symptoms.The cluster analysis of high-frequency acupoints showed that the acupoints of moxibustion for cancer generally work on cultivating yang,supporting the antipathogenic qi,strengthening the spleen and harmonizing the stomach,and were selected in association with the clinical symptoms of different cancers.

A survey on the real-world clinical utilization of a traditional acupuncture in Republic of Korea:Sa-am acupuncture

Objective This study investigated the clinical details and usage of Sa-am acupuncture in Korean medicine clinics and explored how practicing Korean medicine doctors(KMDs)think about Sa-am acupuncture.Methods We conducted a questionnaire-based survey of KMDs who utilize Sa-am acupuncture in their practice.The study comprehensively investigated issues related to clinical application of Sa-am acupuncture,needling techniques used during treatment,training methods,and directions for its future improvement.Results We analyzed 572 responses.An average of 50%of the patients visiting Korean medicine clinics were receiving Sa-am acupuncture.The most prevalent indication for Sa-am acupuncture use was digestive disorders.The patients’appetite level and digestive function were most frequently used indicators for selecting acupuncture points.Regarding prescription compositions,Jung-Gyuk formulas were more frequently used than Seung-Gyuk formulas.Inserting the needle along the flow of the channel or against the flow of the channel was most popular.The acupuncture style most frequently used in combination with Sa-am acupuncture was Ashi point acupuncture.Strengths of Sa-am acupuncture included its versatility,easy application,and good outcomes.Limitations included the lack of rigorous education and training programs,difficulty in applying the principles for beginners,and insufficient clinical research evidence.Conclusion In clinics where Sa-am acupuncture is available,KMDs were providing Sa-am acupuncture to about half of their patients.Practitioners were not using all of the tonification and sedation techniques which may be due to time constraints or simply a lack of necessity.Sa-am acupuncture demonstrated high utility in clinical practice and high satisfaction based on the efficacy and safety.More training programs and high-quality research are needed to help expand the use of Sa-am acupuncture.

The rules of acupoint-selection of acupuncture for polycystic ovary syndrome based on data mining

Objective To excavate and analyze the acupoint selection rules of acupuncture for PCOS. Methods A literature search was conducted in databases of Chinese Biomedicine Database（CBM）, Chinese National Knowledge Infrastructure Database（CNKI）, Wanfang Database, Chongqing VIP Chinese Science and Technology Periodical Database（VIP） and Pub Med. All clinical trials evaluating the effects of acupuncture in the treatment of polycystic ovary syndrome（PCOS） were included with or without methods of randomization and/or control. Four authors extracted information and two reviewers recorded information on titles, journals, interventions, main acupoints in selfestablished Excel sheet. Results The top ten acupoints of acupuncture therapy used most frequently were, by turns, Sānyīnjiāo（三阴交 SP 6）, Guānyuán（关元 CV 4）, Zhōngjí（中极 CV 3）, Zǐgōng（子宫 EX-CA 1）, Qìhǎi（气海 CV 6）, Zúsānlǐ（足三里 ST 36）, Shènshù（肾俞 BL 23）, Tiānshū（天枢 ST 25）, Guīlaí（归来 ST 29）, Zhōngwǎn（中脘 CV 12）. Conclusion Our study indicates that modern acupuncture treatment for PCOS is based on selection of specific acupoints according to traditional Chinese acupuncture theory. Points of spleen meridian, stomach meridian and conception vessel are chosen frequently which are most located on the abdomen and the lower limbs. Specific points used most are the front-mu points, the he-sea points, matching points and the back-shu points.

Acupoint selection rules in treatment of chemotherapy-induced nausea and vomiting with acupuncture and moxibustion

Objective:To analyze the acupoint selection rules in acupuncture treatment for chemotherapy-induced nausea and vomiting(CINV)in China through data mining technology.Methods:The relevant literature on acupuncture treatment for CINV were searched from SinoMed,China National Knowledge Infrastructure(CNKI),Wanfang,VIP and Pubmed databases from the establishment to January 3,2021 and the worksheet was set up for the information extraction of acupuncture-moxibustion prescriptions.Using IBM SPSS Statistics 25.0 and SPSS Modeler 18.0 software,cluster analysis and association rule analysis were conducted to explore the rules of acupoint selection.Results:A total of 179 articles were eligible,including 206 acupuncture prescriptions and 64 acupoints.The total use frequency of acupoints was 784 times.The acupoints with the highest use frequency were Zúsānlǐ(足三里ST36),Zhōngwǎn(中脘CV12)and Nèiguān(内关PC6).The commonly used meridians included stomach meridian of foot-yangming,conception vessel,pericardium meridian of hand-jueyin and bladder meridian of foot-taiyang.The acupoints located on the chest,the abdomen and the lower limbs were mostly selected.Five-shu points and crossing points were highly involved in terms of the specific points.The most common combination was ST36,CV12 and PC6.Conclusion:In treatment of acupuncture for CINV,the acupoints were generally selected from stomach meridian of foot-yangming,conception vessel,pericardium meridian of hand-jueyin.Front-mu points on the chest and the abdomen,the he-sea points and lower he-sea points in the lower limbs are commonly used.The core acupoint prescription of acupuncture for CINV included ST36,CV12 and PC6.

Rules of acupoint and meridian selection in acupuncture-moxibustion for stable angina pectoris

To summarize and analyze the acupoint selection rules in acupuncture-moxibustion for stable angina pectoris. Clinical studies and literature on acupuncture-moxibustion for stable angina pectoris with definite acupoint selection were included through retrieving China National Knowledge Infrastructure（CNKI）,Wanfang Database and VIP in order to analyze the characteristics and rules of acupoint selection in acupuncture-moxibustion treatment for stable angina pectoris. It has been found that the acupoint selection of acupuncture-moxibustion prescriptions for stable angina pectoris focused on specific acupoints.The top 5 acupoints with the highest using frequency included Neiguan（内关PC 6）,Danzhdng（膻中CV17）,Xinshu（心俞BL 15）,Ziusanli（足三里ST 36） and Sanyinjiao（三阴交SP 6）. Acupuncture-moxibustion treatment of stable angina pectoris involved 12 meridians, mainly including the hand-jueyin pericardium meridian, the foot-taiyang bladder meridian, conception vessel, the foot-yangming stomach meridian, the foot-taiyin spleen meridian, and the hand-shaoyin heart meridian, etc., embodying the characteristics and rules of acupoint selection such as ＂highlighting the special treatment effect of acupoints＂ ＂selecting acupoints along the pericardium meridian, bladder meridian and conception vessel, combining the anterior and the posterior acupoints＂, ＂selecting the distal acupoints of spleen and stomach meridians, and focusing on specific acupoints＂, etc.

Acupoint selection rules in acupuncture therapy for postoperative urinary retention after hemorrhoidectomy based on data mining technology

Objective:To explore the core acupoints and combination rules of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy,and,further to analyze the characteristics of the prescription of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy.Methods:Relevant clinical studies in seven databases were searched systematically from database inception to 1 st October 2020.Based on data mining techniques,the core acupoints,characteristics and combination rules of acupuncture therapy for postoperative urinary retention after hemorrhoidectomy were analyzed comprehensively.Statistics collected and analysis of acupoint selection included the frequency of usage of acupoints,the meridian of acupoints,the location of acupoints and the combination of acupoints.Cluster and association analysis were performed utilizing Excel 13.0 and SPSS 26.0.Results:In the 36 studies included,the most frequently adopted acupoint was Sānyīnjiāo(三阴交 SP6);the most frequently adopted meridian was the foot-taiyin spleen meridian;the most frequently involved location was the lower limbs;and the most frequently adopted combination of acupoints was SP6 and Zhōngjí(中极CV 3).Cluster analysis showed that the acupoints could be divided into three categories:the first group comprised SP6 alone;the second group included CV3,Guānyuán(关元CV4),Yīnlíngquán(阴陵泉SP9) and Zúsānlǐ(足三里ST36);and the third group included Pángguāngshū(膀胱俞BL28),Chéngshān(承山BL57),Tàichōng(太冲LR3),Zhìbiān(秩边 BL54),Tàixī(太溪KI6),Hégǔ(合谷 LI4),Xuèhǎi(血海SP10),Qìhǎi(气海CV6) and Shǔidào(水道ST28).Conclusion:It was found that acupuncture therapy for postoperative urinary retention after hemorrhoidectomy mainly follows the four characteristic rules:the selection of acupoints following the meridian,selection of acupoints at local points,selection of acupoints at distal points and selection of acupoints according to special symptoms.

Research on acupoint selection rules of acupuncture for trigeminal neuralgia based on complex network

Objective:To explore the acupoint selection rules of acupuncture for trigeminal neuralgia(TN) based on complex network.Methods:The articles on clinical research of acupuncture for TN published up to March 2019 were searched from the databases,i.e.CNKI,Wanfang,VIP,PubMed,Web of Science and Science Direct.A prescription database of acupuncture for TN was established.Using complex network,the core acupoints and acupoint selection rules were analyzed for TN treated with acupuncture.Results:A total of 304 articles,including 272 acupoint prescriptions were obtained.The complex network constructed for TN treated with acupuncture was in compliance with the small world effect.Using k-core analytic hierarchy process,36 acupoints were screened,and the total frequency of acupoints is1175.Regarding the meridian distribution,the points of yangming meridians of hand and foot were predominated,accounting for 50.21% of the overall(590/1175).In terms of acupoint location,the acupoints on the head and face were predominated,accounting for 52.51%(617/1175).For the types of acupoint,the specific acupoints were predominated,accounting for 71.32%(838/1175) and the majority was the intersecting points,accounting for 33.87%(398/1175).Based on community structure partition,the treatment of TN with acupuncture was divided into the treatment for symptoms,etiological treatment,and mind regulation.Besides,the supplementary acupoints based on the involved nerve branches of TN and those based on syndrome differentiation were recommended.Conclusion:The core acupoints of acupuncture for TN are Hégu(合谷LI4),Xiaguan(下关ST7),Tàichong(太冲LR3),Fēngchí(风池GB20) and Sìbái(四白ST2).In clinical treatment,the main therapeutics include the local analgesia for the symptoms and etiological treatment,associated with mind regulation.

Professor JIA Chun-sheng's case report and his academic thought of invigorating spleen to nourish original qi

Under the influence of academic theories of numerous physicians of TCM such as Li Gao and Li Zhong-zi in antient China, Professor Jia Chun-sheng proposed the academic thought of tonifying spleen and kidney in combination with acupuncture based on his clinical experience for decades. In clinical practice of acupuncture, Zhongwan （中脘 CV 12）, bilateral Tianshu （天枢 ST 25）, Qihai （气海 CV 6）, Guanyuan （关元 CV4） are often selected to invigorate spleen so as to nourish original qi and to treat both spleen and kidney. The above-mentioned five acupoints form a pattern similar to a star according to their location distribution, so it is called the starlike selection method of acupoints, which attaches importance to spleen and kidney （original qi）. Many diseases, especially internal injuries, are often treated with the starlike acupuncture manipulation combined with acupuncture at other acupoints, which achieves good clinical efficacy.

Four cases of pyonex application by Professor WU Mao-wen

WU Mao-wen, the chief physician, applied intracutaneous pyonex in treatment of various pains, internal medicine diseases, and gynecological diseases. This therapy is not only based on such common methods in TCM as ＂retaining in static＂ and ＂selecting points based on pattern differentiation＂ in clinical point selection, but also extends Zhang Zhong-jing prescription theory to ＂acupoint selection＂ and ＂specialized in macro use＂ in acupoint selection of pyonex. The specific experience includes（1） rational use of specific points in fourteen meridians,（2） skillful use of extra points and empirical points in TCM,（3） holographic point selection, and（4） selection of positive points with painful locality taken as an acupoint. The application of pyonex by physician WU Mao-wen is perfect, professional and safe, without pain, and can significantly improve symptoms, so it is worth being promoted.