Background Percutaneous coronary intervention （PCI） is used as a treatment for acute myocardial infarction （AMI）, and one of its major complications is the angiographic no-reflow phenomenon （NR）. Although intra-...Background Percutaneous coronary intervention （PCI） is used as a treatment for acute myocardial infarction （AMI）, and one of its major complications is the angiographic no-reflow phenomenon （NR）. Although intra-aortic balloon pumping （IABP） is sometimes used in such patients to increase the diastolic coronary blood flow, there is little available information regarding the effects of IABP on the angiographic no-reflow phenomenon. Method Twenty-two AMI patient with NR were performed primary PCI between January 2006 and December 2009, of which 12 patients were selected for IABP therapy and the left 10 were selected as the control group by group procedure of odd and even days; We observed the vasoactive substance in both groups on the days of 1, 2, 3, 5, 7, 10 after the different interventions, which include plasma renin activity （PRA）, angiotensin Ⅱ （ANG Ⅱ）, aldosterone （ALD）, adrenaline （E）, and noradrenalin （NE）; In addition, cardiac structure and cardiac ventricle systolic function including left atrium medial diameter （LAMD）, left ventricular medial diameter （LVMD） Finally, left ventricular ejection fraction （LVEF） were evaluated after 10 days, 3 months and 6 months; statistics was taken to analysis. Results According to the time concentration curve, vasoactive substance of the IABP group decreased faster than that of the control group, and this difference had statistical significance （P 〈 0.01 ） ; In terms of LAMD, LVMD, and LVEF, echocardiography difference of the IABP and the control group in 10 days, 3 months, and 6 months also showed statistical significance （P 〈 0.05）. Conclusions IABP can significantly reduce the release of vasoactive substances of NR in patients of primary PCI for AMI; LAMD, LVMD and LVEF in 10 days, 3 months, and 6 months can be improved using this method, which is conducive to recovery of heart function.展开更多
Background Mortality in patients with acute myocardial infarction(AMI)undergoing an intra-aortic balloon pump(IABP)implantation remains high.This study aims to analyze the risk factors and subsequent prognostic impact...Background Mortality in patients with acute myocardial infarction(AMI)undergoing an intra-aortic balloon pump(IABP)implantation remains high.This study aims to analyze the risk factors and subsequent prognostic impact of pulmonary infection in these populations.Methods Data of patients with AMI treated with the IABP between August 2017 and May 2018 was collected retrospectively.A total of 104 AMI patients who underwent the IABP and complicated with postoperative pulmonary infection were assigned to the observation group,meanwhile,73 patients without pulmonary infection were chosen as the control group.The clinical characteristics were compared between two groups of patients,the risk factors and outcomes for the postoperative pulmonary infections were analyzed.Results Pulmonary infection can prolong CCU duration(11.7±8.2 vs.6.5±4.1,P<0.001)and lead to higher in-hospital death(31.5%vs.12.5%,P=0.002).Killip>2 was an independent risk factor for pulmonary infection.In addition,multivariate logistic regression analysis indicated that Killip>2,diabetes,current smoking,and pulmonary infection were independently associated with in-hospital death.Conclusions Postoperative pulmonary infection was a risk factor for poor outcomes in patients with AMI undergoing IABP.It is necessary to take corresponding interventions to reduce the risk of postoperative pulmonary infection.展开更多
文摘Background Percutaneous coronary intervention （PCI） is used as a treatment for acute myocardial infarction （AMI）, and one of its major complications is the angiographic no-reflow phenomenon （NR）. Although intra-aortic balloon pumping （IABP） is sometimes used in such patients to increase the diastolic coronary blood flow, there is little available information regarding the effects of IABP on the angiographic no-reflow phenomenon. Method Twenty-two AMI patient with NR were performed primary PCI between January 2006 and December 2009, of which 12 patients were selected for IABP therapy and the left 10 were selected as the control group by group procedure of odd and even days; We observed the vasoactive substance in both groups on the days of 1, 2, 3, 5, 7, 10 after the different interventions, which include plasma renin activity （PRA）, angiotensin Ⅱ （ANG Ⅱ）, aldosterone （ALD）, adrenaline （E）, and noradrenalin （NE）; In addition, cardiac structure and cardiac ventricle systolic function including left atrium medial diameter （LAMD）, left ventricular medial diameter （LVMD） Finally, left ventricular ejection fraction （LVEF） were evaluated after 10 days, 3 months and 6 months; statistics was taken to analysis. Results According to the time concentration curve, vasoactive substance of the IABP group decreased faster than that of the control group, and this difference had statistical significance （P 〈 0.01 ） ; In terms of LAMD, LVMD, and LVEF, echocardiography difference of the IABP and the control group in 10 days, 3 months, and 6 months also showed statistical significance （P 〈 0.05）. Conclusions IABP can significantly reduce the release of vasoactive substances of NR in patients of primary PCI for AMI; LAMD, LVMD and LVEF in 10 days, 3 months, and 6 months can be improved using this method, which is conducive to recovery of heart function.
文摘Background Mortality in patients with acute myocardial infarction(AMI)undergoing an intra-aortic balloon pump(IABP)implantation remains high.This study aims to analyze the risk factors and subsequent prognostic impact of pulmonary infection in these populations.Methods Data of patients with AMI treated with the IABP between August 2017 and May 2018 was collected retrospectively.A total of 104 AMI patients who underwent the IABP and complicated with postoperative pulmonary infection were assigned to the observation group,meanwhile,73 patients without pulmonary infection were chosen as the control group.The clinical characteristics were compared between two groups of patients,the risk factors and outcomes for the postoperative pulmonary infections were analyzed.Results Pulmonary infection can prolong CCU duration(11.7±8.2 vs.6.5±4.1,P<0.001)and lead to higher in-hospital death(31.5%vs.12.5%,P=0.002).Killip>2 was an independent risk factor for pulmonary infection.In addition,multivariate logistic regression analysis indicated that Killip>2,diabetes,current smoking,and pulmonary infection were independently associated with in-hospital death.Conclusions Postoperative pulmonary infection was a risk factor for poor outcomes in patients with AMI undergoing IABP.It is necessary to take corresponding interventions to reduce the risk of postoperative pulmonary infection.
