Acyldesilylation of 5-trimethylsilyl-2-furancarboxaldehyde with acyl chlorides was investigated and the unexpected 5-acyl-2-dichloromethylfuran were obtained as main products. The expected 5-acyl-2-furancarboxaldehyde...Acyldesilylation of 5-trimethylsilyl-2-furancarboxaldehyde with acyl chlorides was investigated and the unexpected 5-acyl-2-dichloromethylfuran were obtained as main products. The expected 5-acyl-2-furancarboxaldehydes were also found after hydrolyzing of the corresponding dichloro-compounds.展开更多
Naturally occurring 9-(5-pentyl-2-furyl) nonanoic acid which was synthesized through five steps in about 20% overall yield by using 5-trimethylsilyl-2-furancarboxaldehyde as a starling material.
文摘Acyldesilylation of 5-trimethylsilyl-2-furancarboxaldehyde with acyl chlorides was investigated and the unexpected 5-acyl-2-dichloromethylfuran were obtained as main products. The expected 5-acyl-2-furancarboxaldehydes were also found after hydrolyzing of the corresponding dichloro-compounds.
文摘Naturally occurring 9-(5-pentyl-2-furyl) nonanoic acid which was synthesized through five steps in about 20% overall yield by using 5-trimethylsilyl-2-furancarboxaldehyde as a starling material.
