Alzheimer’s Disease Stage Classification Using a Deep Transfer Learning and Sparse Auto Encoder Method

Alzheimer’s Disease(AD)is a progressive neurological disease.Early diagnosis of this illness using conventional methods is very challenging.Deep Learning(DL)is one of the finest solutions for improving diagnostic procedures’performance and forecast accuracy.The disease’s widespread distribution and elevated mortality rate demonstrate its significance in the older-onset and younger-onset age groups.In light of research investigations,it is vital to consider age as one of the key criteria when choosing the subjects.The younger subjects are more susceptible to the perishable side than the older onset.The proposed investigation concentrated on the younger onset.The research used deep learning models and neuroimages to diagnose and categorize the disease at its early stages automatically.The proposed work is executed in three steps.The 3D input images must first undergo image pre-processing using Weiner filtering and Contrast Limited Adaptive Histogram Equalization(CLAHE)methods.The Transfer Learning(TL)models extract features,which are subsequently compressed using cascaded Auto Encoders(AE).The final phase entails using a Deep Neural Network(DNN)to classify the phases of AD.The model was trained and tested to classify the five stages of AD.The ensemble ResNet-18 and sparse autoencoder with DNN model achieved an accuracy of 98.54%.The method is compared to state-of-the-art approaches to validate its efficacy and performance.

Ultrasound liver tumor segmentation using adaptively regularized kernel-based fuzzy C means with enhanced level set algorithm

Purpose-The purpose of this study is to develop a hybrid algorithm for segmenting tumor from ultrasound images of the liver.Design/methodology/approach-After collecting the ultrasound images,contrast-limited adaptive histogram equalization approach(CLAHE)is applied as preprocessing,in order to enhance the visual quality of the images that helps in better segmentation.Then,adaptively regularized kernel-based fuzzy C means(ARKFCM)is used to segment tumor from the enhanced image along with local ternary pattern combined with selective level set approaches.Findings-The proposed segmentation algorithm precisely segments the tumor portions from the enhanced images with lower computation cost.The proposed segmentation algorithm is compared with the existing algorithms and ground truth values in terms of Jaccard coefficient,dice coefficient,precision,Matthews correlation coefficient,f-score and accuracy.The experimental analysis shows that the proposed algorithm achieved 99.18% of accuracy and 92.17% of f-score value,which is better than the existing algorithms.Practical implications-From the experimental analysis,the proposed ARKFCM with enhanced level set algorithm obtained better performance in ultrasound liver tumor segmentation related to graph-based algorithm.However,the proposed algorithm showed 3.11% improvement in dice coefficient compared to graph-based algorithm.Originality/value-The image preprocessing is carried out using CLAHE algorithm.The preprocessed image is segmented by employing selective level set model and Local Ternary Pattern in ARKFCM algorithm.In this research,the proposed algorithm has advantages such as independence of clustering parameters,robustness in preserving the image details and optimal in finding the threshold value that effectively reduces the computational cost.