The hub-driven virtual rail train is a novel urban transportation system that amalgamates the benefits of modern trams and buses.However,this system is plagued by issues such as decreased ride comfort and severe defor...The hub-driven virtual rail train is a novel urban transportation system that amalgamates the benefits of modern trams and buses.However,this system is plagued by issues such as decreased ride comfort and severe deformation of urban roads due to the increase in sprung mass and long-term rolling at the same position.To address these concerns and improve the human-vehicle-road friendliness of the virtual rail train,we propose an Improved Sky-Ground Hook and Acceleration-Driven Damper control(Improved SH-GH-ADD control)strategy for the semi-active suspension system.This control monitors the vibration acceleration signal of the unsprung mass in real-time and selects the mixed Sky-Hook and Acceleration-Driven Damper(SH-ADD)control or the mixed Ground-Hook and Acceleration-Driven Damper(GH-ADD)control based on the positive and negative values of the vibration acceleration of the unsprung mass.The Improved SH-GH-ADD control combines the advantages of SH-ADD control and GH-ADD control to achieve control of the sprung mass and unsprung mass in the full fre-quency band.Finally,through simulation and comparative analysis with traditional SH-ADD,GH-ADD,and mixed SH-GH control,we demonstrate the exceptional performance of the proposed algorithm.展开更多
利用无源车辆ISD(inerter spring damper)悬架系统可有效抑制车身低频振动的特性,结合经典加速度驱动阻尼(acceleration driven damping,ADD)控制可抑制车身中高频振动的特点,提出基于ADD正实网络的车辆ISD悬架综合优化设计方法,将车辆...利用无源车辆ISD(inerter spring damper)悬架系统可有效抑制车身低频振动的特性,结合经典加速度驱动阻尼(acceleration driven damping,ADD)控制可抑制车身中高频振动的特点,提出基于ADD正实网络的车辆ISD悬架综合优化设计方法,将车辆ISD悬架的宽频域振动抑制问题转化为基于ADD网络综合的正实优化控制问题。分别构建一阶和二阶正实网络的悬架动态模型,基于鱼群算法优化悬架结构参数,仿真分析ADD控制与正实网络的耦合作用机理和正实网络阶次对悬架性能的影响。结果表明:悬架的隔振性能随正实网络阶次的升高而提升,ADD网络综合的方法可以有效的实现车辆ISD悬架的宽频域的振动抑制,进一步拓展车辆ISD悬架主动控制的思路。展开更多
目的探讨Beta-adducin（Add2）基因的rs3755351单核苷酸多态性与福建和广东人群中高血压发病的相关性。方法应用MassARRAY-IPLEX技术和基质辅助激光解吸电离飞行时间质谱平台（Matrix-assisted laser desorption/ionization time of fig...目的探讨Beta-adducin（Add2）基因的rs3755351单核苷酸多态性与福建和广东人群中高血压发病的相关性。方法应用MassARRAY-IPLEX技术和基质辅助激光解吸电离飞行时间质谱平台（Matrix-assisted laser desorption/ionization time of fight mass spectrometry,MALDI-TOF-MS）对广东和福建940例高血压患者和944名健康查体者对照进行Add2基因rs3755351位点的基因分型。用χ2检验统计分析病例组和对照组基因型和等位基因的频率;采用非条件Logistic回归分析,计算比值比（OR）和95%CI,评价多态性位点与高血压遗传易感性的相关性。结果 Add2基因rs3755351多态位点有AA,AC和CC三种基因型,在隐性模型中,Add2基因的rs3755351多态位点AA、AC-CC基因型在福建高血压人群中的分布频率为10.5%和89.5%,与对照组（14.2%、85.8%）相比差异有统计学意义（P〈0.05）,与AC或CC基因型相比,携带AA基因型能显著降低患高血压的发病危险（OR=0.65,95%CI：0.43~0.99,P=0.044）;rs3755351的AA、AC和CC基因型在广东高血压人群中的分布频率为15.1%、53.0%和31.8%,与对照组（12.4%、52.4%和35.2%）相比差异无统计学意义（P〉0.05）。结论 Add2基因的rs3755351多态位点与福建人群的高血压遗传易感性相关,与AC或CC基因型相比,携带AA基因型能显著降低患高血压的发病危险;rs3755351在广东人群中未发现与高血压的遗传易感性相关。展开更多
基金This research was funded by Natural Science Foundation of Sichuan Province(2023NSFSC0395)the Sichuan Science and Technology Program(2022ZH CG0061)the SWJTU Science and Technology Innovation Project(2682022CX008).
文摘The hub-driven virtual rail train is a novel urban transportation system that amalgamates the benefits of modern trams and buses.However,this system is plagued by issues such as decreased ride comfort and severe deformation of urban roads due to the increase in sprung mass and long-term rolling at the same position.To address these concerns and improve the human-vehicle-road friendliness of the virtual rail train,we propose an Improved Sky-Ground Hook and Acceleration-Driven Damper control(Improved SH-GH-ADD control)strategy for the semi-active suspension system.This control monitors the vibration acceleration signal of the unsprung mass in real-time and selects the mixed Sky-Hook and Acceleration-Driven Damper(SH-ADD)control or the mixed Ground-Hook and Acceleration-Driven Damper(GH-ADD)control based on the positive and negative values of the vibration acceleration of the unsprung mass.The Improved SH-GH-ADD control combines the advantages of SH-ADD control and GH-ADD control to achieve control of the sprung mass and unsprung mass in the full fre-quency band.Finally,through simulation and comparative analysis with traditional SH-ADD,GH-ADD,and mixed SH-GH control,we demonstrate the exceptional performance of the proposed algorithm.
文摘利用无源车辆ISD(inerter spring damper)悬架系统可有效抑制车身低频振动的特性,结合经典加速度驱动阻尼(acceleration driven damping,ADD)控制可抑制车身中高频振动的特点,提出基于ADD正实网络的车辆ISD悬架综合优化设计方法,将车辆ISD悬架的宽频域振动抑制问题转化为基于ADD网络综合的正实优化控制问题。分别构建一阶和二阶正实网络的悬架动态模型,基于鱼群算法优化悬架结构参数,仿真分析ADD控制与正实网络的耦合作用机理和正实网络阶次对悬架性能的影响。结果表明:悬架的隔振性能随正实网络阶次的升高而提升,ADD网络综合的方法可以有效的实现车辆ISD悬架的宽频域的振动抑制,进一步拓展车辆ISD悬架主动控制的思路。
文摘目的探讨Beta-adducin（Add2）基因的rs3755351单核苷酸多态性与福建和广东人群中高血压发病的相关性。方法应用MassARRAY-IPLEX技术和基质辅助激光解吸电离飞行时间质谱平台（Matrix-assisted laser desorption/ionization time of fight mass spectrometry,MALDI-TOF-MS）对广东和福建940例高血压患者和944名健康查体者对照进行Add2基因rs3755351位点的基因分型。用χ2检验统计分析病例组和对照组基因型和等位基因的频率;采用非条件Logistic回归分析,计算比值比（OR）和95%CI,评价多态性位点与高血压遗传易感性的相关性。结果 Add2基因rs3755351多态位点有AA,AC和CC三种基因型,在隐性模型中,Add2基因的rs3755351多态位点AA、AC-CC基因型在福建高血压人群中的分布频率为10.5%和89.5%,与对照组（14.2%、85.8%）相比差异有统计学意义（P〈0.05）,与AC或CC基因型相比,携带AA基因型能显著降低患高血压的发病危险（OR=0.65,95%CI：0.43~0.99,P=0.044）;rs3755351的AA、AC和CC基因型在广东高血压人群中的分布频率为15.1%、53.0%和31.8%,与对照组（12.4%、52.4%和35.2%）相比差异无统计学意义（P〉0.05）。结论 Add2基因的rs3755351多态位点与福建人群的高血压遗传易感性相关,与AC或CC基因型相比,携带AA基因型能显著降低患高血压的发病危险;rs3755351在广东人群中未发现与高血压的遗传易感性相关。
