Magnetic nanoparticles Fe3O4@SiO2 supported cinchona alkaloids （quinine and quinidine） were successfully synthesized as magnetically recoverable organocatalysts and characterized by FT-IR, XPS, SEM measurements, and...Magnetic nanoparticles Fe3O4@SiO2 supported cinchona alkaloids （quinine and quinidine） were successfully synthesized as magnetically recoverable organocatalysts and characterized by FT-IR, XPS, SEM measurements, and elemental analysis. Their catalytic activity and stereoselectivity were preliminarily evaluated in the asymmetric Michael addition reaction of 1,3-dicarbonyls and maleimides. The supported quinine catalyst exhibited good catalytic efficiency and modest to high enantioselectivity. The magnetic recoverabiliW and recyclability of the catalyst were also examined.展开更多
基金Financial support from the National Natural Science Foundation of China(No. 21472096)
文摘Magnetic nanoparticles Fe3O4@SiO2 supported cinchona alkaloids （quinine and quinidine） were successfully synthesized as magnetically recoverable organocatalysts and characterized by FT-IR, XPS, SEM measurements, and elemental analysis. Their catalytic activity and stereoselectivity were preliminarily evaluated in the asymmetric Michael addition reaction of 1,3-dicarbonyls and maleimides. The supported quinine catalyst exhibited good catalytic efficiency and modest to high enantioselectivity. The magnetic recoverabiliW and recyclability of the catalyst were also examined.
