Purpose–In response to the problem of insufficient traction/braking adhesion force caused by the existence of the third-body medium on the rail surface,this study aims to analyze the utilization of wheel-rail adhesio...Purpose–In response to the problem of insufficient traction/braking adhesion force caused by the existence of the third-body medium on the rail surface,this study aims to analyze the utilization of wheel-rail adhesion coefficient under different medium conditions and propose relevant measures for reasonable and optimized utilization of adhesion to ensure the traction/braking performance and operation safety of trains.Design/methodology/approach–Based on the PLS-160 wheel-rail adhesion simulation test rig,the study investigates the variation patterns of maximum utilized adhesion characteristics on the rail surface under different conditions of small creepage and large slip.Through statistical analysis of multiple sets of experimental data,the statistical distribution patterns of maximum utilized adhesion on the rail surface are obtained,and a method for analyzing wheel-rail adhesion redundancy based on normal distribution is proposed.The study analyzes the utilization of traction/braking adhesion,as well as adhesion redundancy,for different medium under small creepage and large slip conditions.Based on these findings,relevant measures for the reasonable and optimized utilization of adhesion are derived.Findings–When the third-body medium exists on the rail surface,the train should adopt the low-level service braking to avoid the braking skidding by extending the braking distance.Compared with the current adhesion control strategy of small creepage,adopting appropriate strategies to control the train’s adhesion coefficient near the second peak point of the adhesion coefficient-slip ratio curve in large slip can effectively improve the traction/braking adhesion redundancy and the upper limit of adhesion utilization,thereby ensuring the traction/braking performance and operation safety of the train.Originality/value–Most existing studies focus on the wheel-rail adhesion coefficient values and variation patterns under different medium conditions,without considering whether the rail surface with different medium can provide sufficient traction/braking utilized adhesion coefficient for the train.Therefore,there is a risk of traction overspeeding/braking skidding.This study analyzes whether the rail surface with different medium can provide sufficient traction/braking utilized adhesion coefficient for the train and whether there is redundancy.Based on these findings,relevant measures for the reasonable and optimized utilization of adhesion are derived to further ensure operation safety of the train.展开更多
The objective of this paper is to evaluate the Vialit Adhesion Test and its potential for use within performance oriented specifications for seal treatments. Multiple aggregates and emulsions are evaluated with existi...The objective of this paper is to evaluate the Vialit Adhesion Test and its potential for use within performance oriented specifications for seal treatments. Multiple aggregates and emulsions are evaluated with existing test methods and with modified equipment and methods. The results indicate the current test tray is inadequate and that a thicker tray provides better results. Conditioning that incorporated either freeze times between 4 to 8 hours and/or freeze thaw cycles were also found to be improvements to the current conditioning methods. The specified mass of the steel spheres used during the test may be too restrictive in that more economical spheres were tested and did not show differences in aggregate loss.展开更多
Ischemic brain injury causes neuronal death and inflammation.Inflammation activates protein-tyrosine phosphatase 1B(PTP1B).Here,we tested the significance of PTP1B activation in glutamatergic projection neurons on fun...Ischemic brain injury causes neuronal death and inflammation.Inflammation activates protein-tyrosine phosphatase 1B(PTP1B).Here,we tested the significance of PTP1B activation in glutamatergic projection neurons on functional recovery in two models of stroke:by photothrombosis,focal ischemic lesions were induced in the sensorimotor cortex(SM stroke)or in the peri-prefrontal cortex(peri-PFC stroke).Elevated PTP1B expression was detected at 4 days and up to 6 weeks after stroke.While ablation of PTP1B in neurons of neuronal knockout(NKO)mice had no effect on the volume or resorption of ischemic lesions,markedly different effects on functional recovery were observed.SM stroke caused severe sensory and motor deficits(adhesive removal test)in wild type and NKO mice at 4 days,but NKO mice showed drastically improved sensory and motor functional recovery at 8 days.In addition,peri-PFC stroke caused anxiety-like behaviors(elevated plus maze and open field tests),and depression-like behaviors(forced swimming and tail suspension tests)in wild type mice 9 and 28 days after stroke,respectively,with minimal effect on sensory and motor function.Peri-PFC stroke-induced affective disorders were associated with fewer active(FosB+)neurons in the PFC and nucleus accumbens but more FosB+neurons in the basolateral amygdala,compared to sham-operated mice.In contrast,mice with neuronal ablation of PTP1B were protected from anxiety-like and depression-like behaviors and showed no change in FosB+neurons after peri-PFC stroke.Taken together,our study identifies neuronal PTP1B as a key component that hinders sensory and motor functional recovery and also contributes to the development of anxiety-like and depression-like behaviors after stroke.Thus,PTP1B may represent a novel therapeutic target to improve stroke recovery.All procedures for animal use were approved by the Animal Care and Use Committee of the University of Ottawa Animal Care and Veterinary Service(protocol 1806)on July 27,2018.展开更多
In order to investigate the high-temperature performances of the asphalt pavement hot-applied sealant, as well as to reduce failures of the sealant pullout, the softening point test and the flow test(two existing met...In order to investigate the high-temperature performances of the asphalt pavement hot-applied sealant, as well as to reduce failures of the sealant pullout, the softening point test and the flow test(two existing methods for evaluating high-temperature performances) were conducted. It was found that both tests could not accurately reflect the adhesion performances of the sealant at high temperatures. For this purpose, the adhesion test for PSAT(pressure sensitive adhesive tape) has been taken as a reference to develop a device that is suitable for evaluating the adhesion performances, by modifying relevant test parameters according to the road conditions at high temperatures. Thirteen common sealants were tested in the modified adhesion test, softening point test and f low test. The experimental results show that no significant correlation(p〉0.05) exists between the adhesion value, softening point, adhesion value and flow value; while a significant correlation(p〈0.05) exists between the softening point and flow value. The modified adhesion test is efficient in distinguishing the hightemperature adhesion performances of different sealants, and can be used as a standard method for evaluating such performances.展开更多
This paper presents the results of the shear strength(frictional strength) of cemented paste backfillcemented paste backfill(CPB-CPB) and cemented paste backfillerock wall(CPB-rock) interfaces. The frictional be...This paper presents the results of the shear strength(frictional strength) of cemented paste backfillcemented paste backfill(CPB-CPB) and cemented paste backfillerock wall(CPB-rock) interfaces. The frictional behaviors of these interfaces were assessed for the short-term curing times(3 d and 7 d) using a direct shear apparatus RDS-200 from GCTS(Geotechnical Consulting & Testing Systems). The shear(friction) tests were performed at three different constant normal stress levels on flat and smooth interfaces. These tests aimed at understanding the mobilized shear strength at the CPB-rock and CPB-CPB interfaces during and/or after open stope filling(no exposed face). The applied normal stress levels were varied in a range corresponding to the usually measured in-situ horizontal pressures(longitudinal or transverse) developed within paste-filled stopes(uniaxial compressive strength, s c 150 k Pa). Results show that the mobilized shear strength is higher at the CPB-CPB interface than that at the CPB-rock interface. Also, the perfect elastoplastic behaviors observed for the CPB-rock interfaces were not observed for the CPB-CPB interfaces with low cement content which exhibits a strain-hardening behavior. These results are useful to estimate or validate numerical model for pressures determination in cemented backfill stope at short term. The tests were performed on real backfill and granite. The results may help understanding the mechanical behavior of the cemented paste backfill in general and, in particular, analyzing the shear strength at backfillebackfill and backfill-rock interfaces.展开更多
In the process of aeroponics cultivation,the atomizer is one of the most important influencing factors on the cultivation process.This study presented the design of an ultrasonic atomization nozzle using contact charg...In the process of aeroponics cultivation,the atomizer is one of the most important influencing factors on the cultivation process.This study presented the design of an ultrasonic atomization nozzle using contact charging and a root droplet adhesion test rig.The purpose of this study was to reveal the relationship between the main operating parameters of the high-voltage electrostatic ultrasonic atomization nozzle and the atomization effect using droplet adhesion measurements.In this study,the ultrasonic effect of nozzle was achieved by using Laval tube,and the design of the key parameters for the high-voltage electrostatic ultrasonic atomization nozzle were inlet pressure,electrostatic voltage root core electrode material and spray distance;the droplet size variation and root adhesion patterns were obtained through experiments.The best operating parameters were analyzed by using the orthogonal test method,and the droplet deposition distribution of the root system at different scales was investigated in the atomization chamber.The test results revealed that when the root core electrode material was coppe and the nozzle working parameters were at 0.4 MPa of inlet pressure,at 1.75 m the spray distance,at 12 kV of the electrostatic voltage,the root system has the highest droplet adhesion.展开更多
文摘Purpose–In response to the problem of insufficient traction/braking adhesion force caused by the existence of the third-body medium on the rail surface,this study aims to analyze the utilization of wheel-rail adhesion coefficient under different medium conditions and propose relevant measures for reasonable and optimized utilization of adhesion to ensure the traction/braking performance and operation safety of trains.Design/methodology/approach–Based on the PLS-160 wheel-rail adhesion simulation test rig,the study investigates the variation patterns of maximum utilized adhesion characteristics on the rail surface under different conditions of small creepage and large slip.Through statistical analysis of multiple sets of experimental data,the statistical distribution patterns of maximum utilized adhesion on the rail surface are obtained,and a method for analyzing wheel-rail adhesion redundancy based on normal distribution is proposed.The study analyzes the utilization of traction/braking adhesion,as well as adhesion redundancy,for different medium under small creepage and large slip conditions.Based on these findings,relevant measures for the reasonable and optimized utilization of adhesion are derived.Findings–When the third-body medium exists on the rail surface,the train should adopt the low-level service braking to avoid the braking skidding by extending the braking distance.Compared with the current adhesion control strategy of small creepage,adopting appropriate strategies to control the train’s adhesion coefficient near the second peak point of the adhesion coefficient-slip ratio curve in large slip can effectively improve the traction/braking adhesion redundancy and the upper limit of adhesion utilization,thereby ensuring the traction/braking performance and operation safety of the train.Originality/value–Most existing studies focus on the wheel-rail adhesion coefficient values and variation patterns under different medium conditions,without considering whether the rail surface with different medium can provide sufficient traction/braking utilized adhesion coefficient for the train.Therefore,there is a risk of traction overspeeding/braking skidding.This study analyzes whether the rail surface with different medium can provide sufficient traction/braking utilized adhesion coefficient for the train and whether there is redundancy.Based on these findings,relevant measures for the reasonable and optimized utilization of adhesion are derived to further ensure operation safety of the train.
文摘The objective of this paper is to evaluate the Vialit Adhesion Test and its potential for use within performance oriented specifications for seal treatments. Multiple aggregates and emulsions are evaluated with existing test methods and with modified equipment and methods. The results indicate the current test tray is inadequate and that a thicker tray provides better results. Conditioning that incorporated either freeze times between 4 to 8 hours and/or freeze thaw cycles were also found to be improvements to the current conditioning methods. The specified mass of the steel spheres used during the test may be too restrictive in that more economical spheres were tested and did not show differences in aggregate loss.
基金This work was supported by grants from the Heart and Stroke Foundation of Canada(Nos.G-13-0002596&G-18-0022157,to HHCNo.G-16-00014085,to AFRS)+2 种基金the Natural Science and Engineering Research Council of Canada(No.RGPIN/06212-2014,to HHC,No.RGPIN/2016-04985,to AFRS)the Canadian Institutes of Health Research(No.201610PJT,to HHC)HHC is also supported by a Mid-Career Investigator Award(No.7506)from the Heart and Stroke Foundation of Ontario.How to cite this article:Cruz SA。
文摘Ischemic brain injury causes neuronal death and inflammation.Inflammation activates protein-tyrosine phosphatase 1B(PTP1B).Here,we tested the significance of PTP1B activation in glutamatergic projection neurons on functional recovery in two models of stroke:by photothrombosis,focal ischemic lesions were induced in the sensorimotor cortex(SM stroke)or in the peri-prefrontal cortex(peri-PFC stroke).Elevated PTP1B expression was detected at 4 days and up to 6 weeks after stroke.While ablation of PTP1B in neurons of neuronal knockout(NKO)mice had no effect on the volume or resorption of ischemic lesions,markedly different effects on functional recovery were observed.SM stroke caused severe sensory and motor deficits(adhesive removal test)in wild type and NKO mice at 4 days,but NKO mice showed drastically improved sensory and motor functional recovery at 8 days.In addition,peri-PFC stroke caused anxiety-like behaviors(elevated plus maze and open field tests),and depression-like behaviors(forced swimming and tail suspension tests)in wild type mice 9 and 28 days after stroke,respectively,with minimal effect on sensory and motor function.Peri-PFC stroke-induced affective disorders were associated with fewer active(FosB+)neurons in the PFC and nucleus accumbens but more FosB+neurons in the basolateral amygdala,compared to sham-operated mice.In contrast,mice with neuronal ablation of PTP1B were protected from anxiety-like and depression-like behaviors and showed no change in FosB+neurons after peri-PFC stroke.Taken together,our study identifies neuronal PTP1B as a key component that hinders sensory and motor functional recovery and also contributes to the development of anxiety-like and depression-like behaviors after stroke.Thus,PTP1B may represent a novel therapeutic target to improve stroke recovery.All procedures for animal use were approved by the Animal Care and Use Committee of the University of Ottawa Animal Care and Veterinary Service(protocol 1806)on July 27,2018.
基金Funded by the National Natural Science Foundation of China(Nos.51378242 and 51008146)the Transportation Industry Science and Technology Project of Beijing(No.kj2013-2-14)
文摘In order to investigate the high-temperature performances of the asphalt pavement hot-applied sealant, as well as to reduce failures of the sealant pullout, the softening point test and the flow test(two existing methods for evaluating high-temperature performances) were conducted. It was found that both tests could not accurately reflect the adhesion performances of the sealant at high temperatures. For this purpose, the adhesion test for PSAT(pressure sensitive adhesive tape) has been taken as a reference to develop a device that is suitable for evaluating the adhesion performances, by modifying relevant test parameters according to the road conditions at high temperatures. Thirteen common sealants were tested in the modified adhesion test, softening point test and f low test. The experimental results show that no significant correlation(p〉0.05) exists between the adhesion value, softening point, adhesion value and flow value; while a significant correlation(p〈0.05) exists between the softening point and flow value. The modified adhesion test is efficient in distinguishing the hightemperature adhesion performances of different sealants, and can be used as a standard method for evaluating such performances.
文摘This paper presents the results of the shear strength(frictional strength) of cemented paste backfillcemented paste backfill(CPB-CPB) and cemented paste backfillerock wall(CPB-rock) interfaces. The frictional behaviors of these interfaces were assessed for the short-term curing times(3 d and 7 d) using a direct shear apparatus RDS-200 from GCTS(Geotechnical Consulting & Testing Systems). The shear(friction) tests were performed at three different constant normal stress levels on flat and smooth interfaces. These tests aimed at understanding the mobilized shear strength at the CPB-rock and CPB-CPB interfaces during and/or after open stope filling(no exposed face). The applied normal stress levels were varied in a range corresponding to the usually measured in-situ horizontal pressures(longitudinal or transverse) developed within paste-filled stopes(uniaxial compressive strength, s c 150 k Pa). Results show that the mobilized shear strength is higher at the CPB-CPB interface than that at the CPB-rock interface. Also, the perfect elastoplastic behaviors observed for the CPB-rock interfaces were not observed for the CPB-CPB interfaces with low cement content which exhibits a strain-hardening behavior. These results are useful to estimate or validate numerical model for pressures determination in cemented backfill stope at short term. The tests were performed on real backfill and granite. The results may help understanding the mechanical behavior of the cemented paste backfill in general and, in particular, analyzing the shear strength at backfillebackfill and backfill-rock interfaces.
基金financially supported by the National Natural Science Foundation of China Program(Grant No.51975255)Jiangsu Agriculture Science and Technology Innovation Fund(Grant No.CX(18)3048)the“Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions”(Grant No.37,(2014))。
文摘In the process of aeroponics cultivation,the atomizer is one of the most important influencing factors on the cultivation process.This study presented the design of an ultrasonic atomization nozzle using contact charging and a root droplet adhesion test rig.The purpose of this study was to reveal the relationship between the main operating parameters of the high-voltage electrostatic ultrasonic atomization nozzle and the atomization effect using droplet adhesion measurements.In this study,the ultrasonic effect of nozzle was achieved by using Laval tube,and the design of the key parameters for the high-voltage electrostatic ultrasonic atomization nozzle were inlet pressure,electrostatic voltage root core electrode material and spray distance;the droplet size variation and root adhesion patterns were obtained through experiments.The best operating parameters were analyzed by using the orthogonal test method,and the droplet deposition distribution of the root system at different scales was investigated in the atomization chamber.The test results revealed that when the root core electrode material was coppe and the nozzle working parameters were at 0.4 MPa of inlet pressure,at 1.75 m the spray distance,at 12 kV of the electrostatic voltage,the root system has the highest droplet adhesion.