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Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis 被引量:1
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作者 Akira Hokama Takeaki Tomoyose +8 位作者 Yu-ichi Yamamoto Takako Watanabe Tetsuo Hirata Fukunori Kinjo Seiya Kato Koichi Ohshima Hiroshi Uezato Nobuyuki Takasu Jiro Fujita 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第42期6584-6588,共5页
Multiple lymphomatous polyposis (MLP) is an unusual form of non-Hodgkin's lymphoma characterized by polyps throughout the gastrointestinal tract. It has been reported that most MLP are observed in cases with mantl... Multiple lymphomatous polyposis (MLP) is an unusual form of non-Hodgkin's lymphoma characterized by polyps throughout the gastrointestinal tract. It has been reported that most MLP are observed in cases with mantle cell lymphoma of B-cell type. We herein present a case of a 66-year-old man with adult T-cell leukemia/lymphoma (ATLL). Colonoscopy revealed MLP throughout the colon and histopathological findings of ATLL cell infiltration. The patient died despite combination of chemotherapy. The literature of manifestations of colonic involvement of ATLL isreviewed and the importance of endoscopic evaluation to differentiate ATLL intestinal lesions from opportunistic infectious enterocolitis is discussed. 展开更多
关键词 adult t-cell leukemia/lymphoma Multiplelymphomatous polyposis Human t-cell lymphotropicvirus type 1 Strongyloides stercora/is COLONOSCOPY
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Two Cases of Tuberculosis Manifesting as Cutaneous Solitary Mass in Patients with Adult T-Cell Leukemia/Lymphoma
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作者 Monji Koga Masaki Fujita Shinichi Imafuku 《Journal of Tuberculosis Research》 2016年第3期134-139,共6页
Tuberculosis (TB) is a major public health problem worldwide and a large number of fatal cases are still reported. Immunocompetent individuals are naturally susceptible to TB, and immunocompromised patients have a gre... Tuberculosis (TB) is a major public health problem worldwide and a large number of fatal cases are still reported. Immunocompetent individuals are naturally susceptible to TB, and immunocompromised patients have a greater risk of infection. Although patients with adult T-cell leukemia/lymphoma (ATL) are in an immunosuppressed condition, there is only one reported case of TB accompanied with ATL in the English- language literature in the field of dermatology. Here, we report two patients with chronic-type ATL infected with TB manifesting as cutaneous solitary masses. Case 1 was a 58-year-old woman diagnosed with lumbar abscess with pulmonary TB. Case 2 was an 84-year-old woman diagnosed with tuberculous lymphadenitis in the left cervical region. It is important to raise the differential diagnosis of TB and perform tissue culture for acid-fast bacilli as well as Interferon-Gamma release assay test when dermatologists encounter mass lesions in patients with ATL. 展开更多
关键词 TUBERCULOSIS Tuberculous Lymphadenitis IMMUNOSUPPRESSION adult t-cell Leukemia/lymphoma Regulatory t-cell
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人类白血病病毒Ⅰ型致成人T细胞白血病/淋巴瘤的研究进展 被引量:3
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作者 凡琳琳 谈顺 《国际病理科学与临床杂志》 CAS 2010年第4期337-341,共5页
现已证实人类白血病病毒Ⅰ型(human T-cell leukemia virus Type-1,HTLV-Ⅰ)为成人T细胞白血病/淋巴瘤(adult T-cell leukemia/lymphoma,ATLL)的致病病原,在过去的几年中,人们对该肿瘤进行了大量的研究工作并且发现了一些分子遗传学改变... 现已证实人类白血病病毒Ⅰ型(human T-cell leukemia virus Type-1,HTLV-Ⅰ)为成人T细胞白血病/淋巴瘤(adult T-cell leukemia/lymphoma,ATLL)的致病病原,在过去的几年中,人们对该肿瘤进行了大量的研究工作并且发现了一些分子遗传学改变,包括结构基因gag,pol,pro和env,调节基因tax和rex以及最近在pX区域的负股发现的hbz基因和Fra-2等。随着人们对成人T细胞白血病/淋巴瘤相关基因功能的不断探索,该肿瘤的发病机制会更加明确,其临床治疗也会得到进一步的改善。本文对HTLV-Ⅰ及成人T细胞白血病/淋巴瘤近年来的分子遗传学研究结果、临床特征、分子机制及遗传倾向的关系作一介绍。 展开更多
关键词 成人T细胞白血病/淋巴瘤 人类白血病病毒Ⅰ型 基因
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