With the rapid development of the technology of information network and the era of big data,information technology is now widely used in the field of education.Comprehensive popularity of mobile phones,computers,table...With the rapid development of the technology of information network and the era of big data,information technology is now widely used in the field of education.Comprehensive popularity of mobile phones,computers,tablet computers and portable communication devices and WIFI also facilitate the widespread use of online learning,learning in free time,free learning and other modes.The emergence of microlecture follows the learning mode and trend of modern society,special for young medical students who are highly passionate in accepting new things and have a strong ability in using information technology.In this paper,the necessity and feasibility of self-directed teaching methods related to microlecture and flipped classroom in the teaching in a non-directly affiliated hospital.Using the advantages of the"microlecture and flipped classroom"teaching model,it is possible to improve the learning effect of medical students,construct high-quality online courses,and make quality teaching resources widely shared.展开更多
Objective To investigate the status and trends of nosocomial infection in children’s hospital to provide references for prevention and control of nosocomial infection.Methods The retrospective study was conducted to ...Objective To investigate the status and trends of nosocomial infection in children’s hospital to provide references for prevention and control of nosocomial infection.Methods The retrospective study was conducted to analyze the data of nosocomial infection at Zhejiang University affiliated Children’s Hospital from 2005 to 2014.展开更多
Objective To assess the effect of tetrandrine (Tet) pulmonary targeting microspheres on hypoxic pulmonary hypertension and evaluate its selective action on pulmonary circulation.Methods Twenty rats were exposed to h...Objective To assess the effect of tetrandrine (Tet) pulmonary targeting microspheres on hypoxic pulmonary hypertension and evaluate its selective action on pulmonary circulation.Methods Twenty rats were exposed to hypoxic conditions for 3 weeks. Ten rats were used as normoxic controls. We administered Tet pulmonary targeting microspheres to 10 hypoxic rats and Tet aqueous solution to 10 hypoxic rats and the 10 control rats. Mean pulmonary arterial pressure (mPAP) was measured by a right cardiac catheterization, and mean systemic blood pressure (mSBP) was measured by left femoral catheterization. Results Rats exposed to hypoxia developed pulmonary hypertension. The decrease in mPAP in rats treated with Tet pulmonary targeting microspheres was significantly greater than that in rats receiving Tet aqueous solution (P【0.05), and the effects were longer with Tet pulmonary targeting microspheres. Moreover, Tet pulmonary targeting microspheres, unlike Tet aqueous solution, did not decrease mSBP.Conclusion Tet pulmonary targeting microspheres were more effective than Tet aqueous solution in treating hypoxic pulmonary hypertension and acted selectively on the pulmonary circulation.展开更多
Objective: To study the altering rule of coagulation function at molecular level in patients with secondary brain injury (SBI). Methods: Tissue factor (TF) and tissue factor pathway inhibitor (TFPI) were studied in 32...Objective: To study the altering rule of coagulation function at molecular level in patients with secondary brain injury (SBI). Methods: Tissue factor (TF) and tissue factor pathway inhibitor (TFPI) were studied in 32 patients 1, 2, 3 and 7 days after craniocerebral injury. Repeated cranial CT scans and platelet counts were made simultaneously. Same measurements were done in 30 normal adults except CT scan. Results: No obvious difference was found in age, sex and platelet count between the injured and the normal groups. TFPI/TF decreased markedly in the first week after injury in patients with SBI, but only decreased on the 7th day in the patients without obvious SBI. For the patients who developed delayed intracranial hematoma (DIH) or hematoma enlargement, TF rose only 1 and 2 days after injury, but TFPI had a tendency to rise again after a fall on the 3rd day. For those patients who developed no DIH, TF rose all the time within the 1st week. Conclusions: Decrease of TFPI/TF for a long time, especially within 3 days after injury, may be one of the most important reasons for SBI. High expression of TF for a relative short time and increase of TFPI after a fall within 3 days may be one of the important reasons for DIH or hematoma enlargement.展开更多
基金This work was supported by the Weifang Medical College 2019 University-level Teaching Reform and Research Project(Grant No:2019ZXSJ029).
文摘With the rapid development of the technology of information network and the era of big data,information technology is now widely used in the field of education.Comprehensive popularity of mobile phones,computers,tablet computers and portable communication devices and WIFI also facilitate the widespread use of online learning,learning in free time,free learning and other modes.The emergence of microlecture follows the learning mode and trend of modern society,special for young medical students who are highly passionate in accepting new things and have a strong ability in using information technology.In this paper,the necessity and feasibility of self-directed teaching methods related to microlecture and flipped classroom in the teaching in a non-directly affiliated hospital.Using the advantages of the"microlecture and flipped classroom"teaching model,it is possible to improve the learning effect of medical students,construct high-quality online courses,and make quality teaching resources widely shared.
文摘Objective To investigate the status and trends of nosocomial infection in children’s hospital to provide references for prevention and control of nosocomial infection.Methods The retrospective study was conducted to analyze the data of nosocomial infection at Zhejiang University affiliated Children’s Hospital from 2005 to 2014.
文摘Objective To assess the effect of tetrandrine (Tet) pulmonary targeting microspheres on hypoxic pulmonary hypertension and evaluate its selective action on pulmonary circulation.Methods Twenty rats were exposed to hypoxic conditions for 3 weeks. Ten rats were used as normoxic controls. We administered Tet pulmonary targeting microspheres to 10 hypoxic rats and Tet aqueous solution to 10 hypoxic rats and the 10 control rats. Mean pulmonary arterial pressure (mPAP) was measured by a right cardiac catheterization, and mean systemic blood pressure (mSBP) was measured by left femoral catheterization. Results Rats exposed to hypoxia developed pulmonary hypertension. The decrease in mPAP in rats treated with Tet pulmonary targeting microspheres was significantly greater than that in rats receiving Tet aqueous solution (P【0.05), and the effects were longer with Tet pulmonary targeting microspheres. Moreover, Tet pulmonary targeting microspheres, unlike Tet aqueous solution, did not decrease mSBP.Conclusion Tet pulmonary targeting microspheres were more effective than Tet aqueous solution in treating hypoxic pulmonary hypertension and acted selectively on the pulmonary circulation.
文摘Objective: To study the altering rule of coagulation function at molecular level in patients with secondary brain injury (SBI). Methods: Tissue factor (TF) and tissue factor pathway inhibitor (TFPI) were studied in 32 patients 1, 2, 3 and 7 days after craniocerebral injury. Repeated cranial CT scans and platelet counts were made simultaneously. Same measurements were done in 30 normal adults except CT scan. Results: No obvious difference was found in age, sex and platelet count between the injured and the normal groups. TFPI/TF decreased markedly in the first week after injury in patients with SBI, but only decreased on the 7th day in the patients without obvious SBI. For the patients who developed delayed intracranial hematoma (DIH) or hematoma enlargement, TF rose only 1 and 2 days after injury, but TFPI had a tendency to rise again after a fall on the 3rd day. For those patients who developed no DIH, TF rose all the time within the 1st week. Conclusions: Decrease of TFPI/TF for a long time, especially within 3 days after injury, may be one of the most important reasons for SBI. High expression of TF for a relative short time and increase of TFPI after a fall within 3 days may be one of the important reasons for DIH or hematoma enlargement.
