Laparoscopic spleen-preserving total pancreatectomy for the treatment of low-grade malignant pancreatic tumors:Two case reports and review of literature

BACKGROUND Function-preserving pancreatectomy can improve the long-term quality of life of patients with benign or low-grade malignant tumors,such as intraductal papillary mucinous neoplasms(IPMNs)and mucinous cystic neoplasms.However,there is limited literature on laparoscopic spleen-preserving total pancreatectomy(LSpTP)due to technical difficulties.CASE SUMMARY Patient 1 was a 51-year-old male diagnosed with IPMN based on preoperative imaging,showing solid nodules in the pancreatic head and diffuse dilation of the main pancreatic duct with atrophy of the distal pancreas.We performed L-SpTP with preservation of the splenic vessels,and the postoperative pathology report revealed IPMN with invasive carcinoma.Patient 2 was a 60-year-old male with multiple cystic lesions in the pancreatic head and body.L-SpTP was performed,and intraoperatively,the splenic vein was injured and required ligation.Postoperative pathology revealed a mucinous cystic tumor of the pancreas with low-grade dysplasia.Both patients were discharged on postoperative day 7,and there were no major complications during the perioperative period.CONCLUSION We believe that L-SpTP is a safe and feasible treatment for low-grade malignant pancreatic tumors,but more case studies are needed to evaluate its safety,efficacy,and long-term outcomes.

Role of vascular endothelial growth factor in reconstructive surgery after surgical excision of malignant tumor

As a key mediator of normal physiological angiogenesis, vascular endothelial growth factor(VEGF) has been regarded as an emancipator to plastic surgeon, and yet a misfortune to oncology surgeon, due to its singular biological effect. Therefore in some clinical cases, especially for some malignant tumor patients having endured radical surgery and being craving for a reconstructive surgery, VEGF plays a role full of paradoxes. To make a clinical balance, we should find a point to inhibit tumor cell from utilizing VEGF and make a permission to normal tissues to employ it.

Clinicopathological study of malignant peripheral nerve sheath tumors in the head and neck:Case reports and review of literature

BACKGROUND Malignant peripheral nerve sheath tumor(MPNST)is a rare and aggressive soft tissue sarcoma that poses a major diagnostic and therapeutic challenge.CASE SUMMARY We retrospectively reviewed patients with head and neck MPNSTs treated in our hospital from 2000 to 2021.The clinical features,pathological manifestations,treatments,and prognoses were summarized.We also reviewed the literature,focusing on MPNST in the mandible and maxilla.The study population consisted of five women and five men aged 22–75 years(mean age,49 years).Of the 10 patients,7 were initial cases and 3 were recurrent cases.All lesions were sporadic.The most common site was the mandible.The most frequently encountered symptoms were a progressive mass and local swelling.Complete or partial loss of trimethylation at lysine 27 of histone H3(H3K27me3)was evident on staining in four of nine cases(one case was excluded due to lack of tissue for evaluation of loss of H3K27me3).The 2-and 5-year disease-specific survival rates were 86%a nd 43%,respectively.The average survival time was 64 mo.CONCLUSION MPNST is a highly malignant tumor with a poor prognosis,prone to a high risk of recurrence and distant metastasis.Complete surgical resection is the main treatment.

Application of traditional Chinese medicine acupoint needle embedding combined with emotional nursing in patients with gynecological malignant tumors

BACKGROUND Few relevant literature reports on applying acupoint press-needle embedding combined with emotional nursing in patients with a gynecological malignant tumor.AIM To explore the effect of traditional Chinese medicine acupoint needle embedding combined with emotional nursing on chemotherapy-related nausea and vomiting(CINV),cancer-related fatigue(CRF)and psychological state in patients with gynecological malignant tumors.METHODS Retrospective analysis of the clinical information of 84 patients with gynecological malignant tumors treated in our hospital from August 2020 to December 2022 Led to the development of an observation group(n=42)and a control group(n=42)based on various nursing approaches.Ondansetron hydrochloride injection was administered to the individuals in the control group.However,the observation group received emotional nursing based on the control group and acupoint pressneedle embedding of traditional Chinese medicine.Patients in both groups received the chemotherapy regimen of paclitaxel liposome+carbo-platin/cisplatin.For four weeks,both groups intervened.The CINV grade,quality of life,CRF,psychological status and sleep quality scores of the two groups before and RESULTS After intervention,the degree of CINV in the observation group was significantly better than that in the control group.After intervention,the scores of each dimension and total score of FLIE scale were significantly higher than those in the control group.After intervention,the scores of each dimension and total score of Piper Fatigue Scale were significantly lower than those in the control group(P<0.05).After intervention,the scores of avoidance and yield dimensions in the observation group were significantly lower than those in the control group,and the scores of confrontation dimension were significantly higher than those in the control group(P<0.05).After intervention,the sleep quality score of the observation group was significantly lower than that of the control group,and the Karnofsky Performance Status scale score was significantly higher than that of the control group(P<0.05).CONCLUSION The acupuncture point needle embedding of traditional Chinese medicine combined with emotional nursing can further reduce the incidence of chemotherapy-related nausea and vomiting in patients with gynecological malignant tumors,improve the quality of life and the degree of CRF,alleviate the bad psychological state,adopt a positive way to face the disease and treatment,and improve the quality of sleep and quality of life.

Oncology and reproductive outcomes over 16 years of malignant ovarian germ cell tumors treated by fertility sparing surgery

BACKGROUND Malignant ovarian germ cell tumors(MOGCT)are rare and frequently occur in women of young and reproductive age and the oncologic and reproductive outcomes after fertility-sparing surgery(FSS)for this disease are still limited.AIM To evaluate the oncology and reproductive outcomes of MOGCT patients who underwent FSS.METHODS All MOGCT patients who underwent FSS defined as the operation with a preserved uterus and at least one side of the ovary at our institute between January 2005 and December 2020 were retrospectively reviewed.RESULTS Sixty-two patients were recruited for this study.The median age was 22 years old and over 77%were nulliparous.The three most common histology findings were immature teratoma(32.2%),dysgerminoma(24.2%),and yolk sac tumor(24.2%).The distribution of stage was as follows;Stage I,74.8%;stage II,9.7%;stage III,11.3%;and stage IV,4.8%.Forty-three(67.7%)patients received adjuvant chemotherapy.With a median follow-up time of 96.3 mo,the 10-year progressionfree survival and overall survival were 82.4%and 91%,respectively.For reproductive outcomes,of 43 patients who received adjuvant chemotherapy,18(41.9%)had normal menstruation,and 17(39.5%)resumed menstruation with a median time of 4 mo.Of about 14 patients who desired to conceive,four were pregnant and delivered good outcomes.Only one case was aborted.Therefore,the successful pregnancy rate was 28.6%CONCLUSION The oncology and reproductive outcomes of MOGCT treated by FSS are excellent.Many patients show a long survival time with normal menstruation.However,the obstetric outcome is not quite satisfactory.

Extrathyroidal Implantation of Thyroid Hyperplastic/neoplastic Cells after Endoscopic Thyroid Surgery

Objective To report a case of the implantation of thyroid hyperplastic or neoplastic tissue after endoscopic thyroidectomy and discuss this complication in aspects of prevalence, pathogenesis, protection, and therapies. Methods A systematic search of literature from the PubMed database was conducted for identifying eligible studies on implantation of thyroid hyperplastic or neoplastic cells after endoscopic thyroid surgery. Results Overall, 5 reported cases on patients suffering from endoscopic thyroid surgery with implantation of thyroid hyperplastic or neoplastic cells were included in the systematic review. Conclusions Unskilled surgeons, rough intraoperative surgical treatment, scarification or rupture of tumor, contamination of instruments, chimney effect, aerosolization of tumor cells may be associated with the implantation after endoscopic thyroidectomy. To minimize the risk of such complication, we should be more meticulous and strict the endoscopic surgery indications.

Advances of Prevention and Nursing of Deep Venous Thrombosis after Gynecological Tumor Operation

Emainly includes deep venous thrombosis(DVT)and pulmonary thromboembolism(PTE).DVT is caused by the thrombogenesis of red blood cells,platelets and fibrous protein which obstructs the venous backflow leading to inflam-matory changes in the wall of the vein.PTE is caused by the caducous blood clots of DVT that runs with the blood to the lungs.Because DVT and PTE are the venous thromboembolic disease process in two stages,the prevention of DVT and PTE is very important for preventing the rapid onset of PTE and high mortality rate of the postoperative complications.The changes of female hormones and the blood concentration and lipid metabolism disorders make venous thromboembolism more likely to occur during pregnancy.Once the pulmonary vessels were blocked,the patients’life would be threatened severely.To find a more effective way to prevent postoperative venous thrombosis in gynecology we review the prevention and treatment of deep venous thrombosis after gynecological surgery in this paper.

Primary acinic cell carcinoma of the breast: A case report and review of literature

BACKGROUND In the current World Health Organization classification,acinic cell carcinoma(AcCC)of the breast is considered a rare histological subtype of triple-negative breast cancer.Because of the few reports in the literature,data concerning clinical outcomes are limited.Here,we report a case of AcCC of the breast in a 48-year-old woman.A 48-year-old woman with a mass in her right breast came to our hospital for further diagnosis.Mammography and an ultrasound(US)scan showed a mass in the upper inner side of the right breast.She then underwent surgery to resect the mass in her right breast.Postoperative pathological examination revealed that the tumor had abundant acinar-like structures formed by tumor cells with prominent eosinophilic granules in the cytoplasm,consistent with acinar cell carcinoma.The results of immunohistochemical analysis supported the diagnosis of breast acinar cell carcinoma.Two months later,she underwent breast-conserving surgery and sentinel lymph node biopsy.The pTNM stage was T2N0M0.After surgery,the patient received 30 radiotherapy sessions.The patient was followed up for a period of one year,and no recurrence was found.AcCC of the breast is a rare type of malignant tumor.Because it is usually asym-ptomatic and can be detected by imaging studies,routine breast US or mamm-ograms are important.However,there are no characteristic diagnostic imaging findings or clinical manifestations,so immunohistochemical examination is critical for an accurate diagnosis of AcCC of the breast.

A RETROSPECTIVE ANALYSIS OF SURGICAL TREATMENT FOR BREAST MALIGNANT TUMORS

Objective: To review the evolution of the current surgical treatment for breast malignant tumors over the past twenty years in the First Hospital of Jilin University (the former Bethune University of Medical Sciences). Methods: 1195 eligible patients with primary breast malignant tumor diagnosed and surgically treated at the First Teaching Hospital from January 1980 and December 2000 were retrospectively analyzed. Results: The peak frequency was in 40–49 years of age (40.00%), the age of the patients with breast malignant tumors trends to become young. The most common pTNM classification was Stage II. The most common histological type was infiltrating ductal carcinoma (398 patients, 33.31%), and simple carcinoma (279 patients, 23.53%). Modified radical mastectomy was the most common operation procedure performed (779 patients, 65.19%), and was increasingly used while radical mastectomy was adopted decreasingly in recent decade. Conclusion: The variation of operation procedures performed on patients with breast malignant tumors reflected the advance of our understanding of the biology of cancer and the progression of new treatment principles.

Clinical Study of Aminolevulinic Acid-mediated Acid Photodynamic Therapy Combined with Surgical Therapy of Skin Malignant Tumor

The purpose of the study was to analyze the effects of aminolevulinic acid-mediated photodynamic therapy(ALA-PDT)combined with surgery and its prognostic implications.Firstly,70 cases of skin malignant tumors admitted to the dermatology department of our hospital from January 2017 to December 2018 were selected and divided into observation group and control group according to the random number table,with 35 patients in each group.Observation group adopted the ALA-PDT combined with surgery therapy,and control group adopted surgery therapy.Two groups of patients were last follow-up to December 2019.The results showed that the total effective rate of clinical treatment in the observation group was significantly higher than that in the control group(P<0.05),indicating that based on the basis of conventional surgical treatment,combined use of ALA-PDT can effectively improve the clinical therapeutic effect and better promote the patient’s health recovery.Therefore,combined with surgical treatment,ALA-PDT can improve the clinical efficacy of skin malignant tumors with fewer adverse reactions,high safety,low recurrence rate and ideal long-term prognosis.

Psychological Intervention and Nursing Analysis of Gynecological Malignant Tumors during Chemotherapy

Objectives:To explore the clinical effect of psychological intervention and nursing during the chemotherapy of gynecological malignant tumor.Methods:120 patients with gynecologic malignancies were selected as subjects.According to the nursing method,these patients were divided into intervention group and control group,with 60 cases in each group.The patients in the control group were given routine care,and the patients in the observation group were given psychological intervention care on the basis of routine nursing.Before and after treatment,the anxiety and depression of the two groups were compared using the Self-rating Anxiety Scale(SAS)and the Self-rating Depression Scale(SDS).The satisfaction and adverse reactions of the two groups were compared.The results were statistically analyzed.Results:After nursing intervention,the anxiety and depression scores of the intervention group were lower than those of the control group(P<0.05).The incidence of nausea,vomiting and fatigue in the intervention group was significantly lower than that in the control group(P<0.01).There was no significant difference in the symptoms of diarrhea between the two groups(P>0.05).After the treatment,the satisfaction of the intervention group was significantly higher than that of the control group(P<0.05).Conclusions:During the chemotherapy of gynecological malignant tumor patients,psychological intervention nursing can alleviate the anxiety and depression of patients,improve the complications,and improve the satisfaction of patients.It is worthy of clinical application.

Primary hepatic solitary fibrous tumor with histologically benign and malignant areas

Extrapleural solitary fibrous tumor （SFT） is an uncommon mesenchymal neoplasm, presenting most commonly in the intrathoracic sites but which has been reported at nu- merous extrathoracic locations. The majority of intra-thoracic SFTs are benign, but 10%-15% behave aggressively. We report a case of primary hepatic SFT with histologically benign and ma- lignant areas. A 65-year-old man underwent an abdominal CT scan following a cerebrovascular accident, which demonstrated a sharply demarcated large liver mass with a heterogenous enhancing area and occupying most of the left lobe of the liver. Histological examination following a hemihepatectomy showed an SFT with morphological patterns ranging from benign to malignant areas, including pleomorphism, increased cellularity, herringbone pattern, necrosis and a raised mitotic count. On review of the literature, only an occasional case report with malignant areas in a hepatic SFT was identified. This case highlights that SFT should be included in the differential diagnosis of a hepatic spindle cell lesion, and that on rare occasions, malignant areas can occur in this already uncommon neoplasm.

Endometrial Polyps:Which Patients Should Be Selected for Hysteroscopic Surgery?--A Study Using Data from the Swedish National Quality Registry of Gynecological Surgery

Objective: To illuminate the findings after hysteroscopic surgery of endometrial polyps. Method: Data were extracted from The Swedish National Quality Registry of Gynecological Surgery. Endometrial polyps were identified in 1934 cases in a total of 4512 hysteroscopic operations. Data on all hysteroscopic procedures registered as surgery of endometrial polyps between 1997 and January 2013 were analyzed with logistic regression analysis and effect size was calculated. Main outcome measure was malignancy in endometrial polyps. Results: The most frequently reported symptoms of endometrial polyps were: postmenopausal bleeding, metrorrhagia, pain, and infertility. Among the registered biopsies, there were: 30 malignancies (1.8%), and 41 dysplasias (2.5%). The remaining polyps were benign. Only 1/30 cancer patients were <52 years old (p < 0.001). Among those women with dysplasia, 12/41 (29%) were p = 0.07). All cancer patients at age ≥52 had postmenopausal bleeding. The <52-year-old cancer patient had treatment-resistant bleeding. Increasing weight was a risk factor associated with tissue alterations in endometrial polyps (p = 0.014), controlling for age as a confounding factor. Conclusion: Hysteroscopic surgery should be recommended for women with postmenopausal bleeding and presence of endometrial polyps according to the findings of this study. The results further indicate a low risk of malignancy in premenopausal women <52 years with endometrial polyps. In those cases, it seems to be safe to refrain from surgery.

Evolution-driven crosstalk between glioblastoma and the tumor microenvironment

Glioblastoma(GBM)is a malignant adult brain tumor for which 90%of patients experience recurrence within a year after surgery1.Evolution confers treatment resistance capabilities on tumors2.The diversification of malignant and non-malignant(i.e.,stromal and immune cell)compartments in the tumor microenvironment(TME)during tumor evolution3-7 eventually results in the formation of a complex interaction network that promotes tumor progression.

手术机器人在妇科恶性肿瘤手术中的临床应用分析

目的:分析探讨机器人辅助下妇科恶性肿瘤手术的安全性、可行性及临床价值。方法:回顾性总结吉林省肿瘤医院2014年10月—2020年3月实施的213例达芬奇机器人妇科恶性肿瘤手术病例,其中宫颈癌122例,子宫内膜癌89例,卵巢癌(补充手术)1例,阴道癌1例。分析患者的临床资料、手术情况及治疗效果,并对手术时间、术中失血量、术后肠道功能恢复时间、膀胱功能恢复时间、腹部切口愈合时间、淋巴结切除数目、术后并发症发生情况(出血、感染、尿潴留、肠梗阻、下肢静脉血栓等)、总住院时间、至少1年的随访结果等指标进行评估。结果:213例手术均顺利完成,无中转开腹或更改术式。无术中并发症(如重要血管大出血,膀胱、输尿管、肠道损伤等)发生。术后出现双侧淋巴囊肿4例,单侧淋巴囊肿10例,其中1例淋巴囊肿感染,经超声穿刺、抗感染后好转,其余经对症处置后减轻;单侧下肢肌间静脉血栓1例,经溶栓治疗后好转;尿潴留1例,经膀胱功能锻炼后导尿管顺利拔出;阴道断端愈合差1例,经阴道消毒、上药后愈合良好。术后规范治疗,随访时间为12~52个月,其中1例宫颈高级别神经内分泌癌患者于术后13个月发生肺转移、锁骨上淋巴结转移,于术后25个月死亡;1例阴道癌患者于治疗结束31个月后复发,后放弃治疗失访;1例卵巢癌补充根治术患者于术后17个月复发,后放弃治疗并死亡。结论:达芬奇机器人手术系统应用于妇科恶性肿瘤手术安全、可行,其微创优势明显,患者创伤小、出血少、恢复快,手术安全性高,具有临床应用价值,值得临床推广。

妇科恶性肿瘤患者家庭照顾负荷现状调查及影响因素分析

目的:分析妇科恶性肿瘤患者家庭照顾负荷现状及影响因素。方法:采用便利抽样方法,选取2022年3月-2024年1月在本院就诊的妇科恶性肿瘤患者的照顾者进行问卷调查。使用照顾负荷问卷(CBI)评估照顾者照顾负荷水平,总分96分,0~32分为CBI较低组,33~96分为CBI较高组。采用单因素及logistic回归分析影响照顾者CBI评分可能影响因素。结果:共发放问卷297份,有效问卷290份,有效率97.6%。290例照顾者的CBI为60.36±5.55分,其中CBI≤32分110例(37.9%),≥33分180例(62.1%)。单因素及多元回归分析显示,照顾者年龄大、文化程度低、月收入低、居住在农村、每日照顾时间长、患者患病时间长、患者年住院次数多是妇科恶性肿瘤患者照顾者CBI评分升高影响因素(P<0.05)。结论:本次调查的妇科肿瘤患者CBI评分较高,照顾负荷相对较重,照顾者年龄大、文化程度低、月收入低、居住农村、每日照顾时间长,以及患者患病时间长、年住院次数多是影响照顾者CBI独立因素。提高恶性肿瘤患者社会及家庭支持,构建基于医院-社区-家庭三元联动的健康管理模式等将有助于缓解恶性肿瘤患者家庭照顾负荷,对恶性肿瘤患者的疾病治疗和康复有重要意义。

基于加速康复外科理念的术前预康复护理模式在妇科肿瘤患者中的应用

目的探讨基于加速康复外科(ERAS)理念的术前预康复护理模式在妇科肿瘤患者中的应用效果。方法选取2022年7月至2023年3月于九江市妇幼保健医院接受手术治疗的50例妇科肿瘤患者为研究对象,采用随机数表法将患者分为对照组和观察组,各25例。对照组采取常规护理,观察组在对照组基础上采取基于ERAS理念的术前预康复护理。比较两组心理状态、术后康复进程以及术后并发症发生率。结果干预前,两组患者焦虑自评量表(SAS)、抑郁自评量表(SDS)评分比较,差异无统计学意义(P>0.05);干预后,两组患者SAS、SDS评分均低于干预前,且观察组患者SAS、SDS评分均低于对照组,差异有统计学意义(P<0.05);观察组患者胃肠通气时间、术后下床平均活动时间、术后首次进食时间和住院时间均短于对照组,差异有统计学意义(P<0.05);观察组患者并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论在妇科肿瘤患者中采取基于ERAS理念的术前预康复护理模式,可有效减少患者负面情绪,降低术后腹胀、尿潴留等并发症发生率,从而促进患者康复。

妇科恶性肿瘤患者灵性需求现状及影响因素分析

目的了解妇科恶性肿瘤患者灵性需求现状并分析其影响因素。方法选取2021年10月至2023年10月赣州市人民医院收治的145例妇科恶性肿瘤患者作为研究对象,采用中文版领悟社会支持量表(PSSS)、中文版灵性需求量表(SNS)及一般资料调查表进行调查,根据患者是否存在灵性需求分为需求组(n=107)、对照组(n=38),通过单因素分析、logistic回归分析妇科恶性肿瘤患者灵性需求的影响因素。结果145例妇科恶性肿瘤患者灵性需求评分为(76.94±10.85)分,其中107例存在灵性需求,占比为73.79%;需求组与对照组患者的年龄、婚姻状况、子女数量、居住地、疾病种类、肿瘤分期、固定照顾者比较,差异无统计学意义(P>0.05);两组患者的文化水平、宗教信仰、病程、家庭人均收入及社会支持比较,差异有统计学意义(P<0.05)。logistic回归分析结果提示,专科及以上文化水平(β=1.138,OR=3.119,95%CI=1.098~8.864)、有宗教信仰(β=2.231,OR=10.108,95%CI=1.236~82.627)、病程>12月(β=1.385,OR=3.994,95%CI=1.491~10.698)、家庭人均收入≥4000元(β=1.668,OR=5.408,95%CI=1.443~20.265)及社会支持高(β=1.002,OR=2.724,95%CI=1.109~6.691)是妇科恶性肿瘤患者灵性需求的危险因素(P<0.05)。结论妇科恶性肿瘤患者灵性需求处于中高水平,其水平受患者文化水平、宗教信仰、病程、家庭人均收入及社会支持的影响。

急性冠脉综合征合并恶性肿瘤患者冠脉介入术后的预后分析

目的 分析急性冠脉综合征(ACS)合并恶性肿瘤患者经冠脉介入术后的预后。方法 回顾性分析84例行冠脉介入术治疗的ACS合并恶性肿瘤患者的病历有关资料。在患者行冠脉介入术治疗后进行2年随访,依据患者的临床结局将其分为生存组与死亡组。运用多因素Logistic回归分析模型探究ACS合并恶性肿瘤患者行冠脉介入术治疗后死亡的影响因素。结果 随访2年,84例行冠脉介入术治疗的ACS合并恶性肿瘤患者中,共14例死亡,70例生存。单因素分析显示:年龄、性别、高血压、体重指数(BMI)、陈旧性心肌梗死、高脂血症、血红蛋白(HB)、肠外抗凝治疗与ACS合并恶性肿瘤患者冠脉介入术后死亡无关(P>0.05),糖尿病、吸烟、脑钠肽(BNP)水平、血小板计数(PLT)与ACS合并恶性肿瘤患者冠脉介入术后死亡有关(P<0.05);多因素Logistic回归分析显示:糖尿病(OR=9.167,95%CI=2.311~36.360)、吸烟(OR=16.105,95%CI=3.294~78.734)、BNP水平升高(OR=19.759,95%CI=4.634~359.79)、PLT减少(OR=18.231,95%CI=3.954~230.64)为ACS合并恶性肿瘤患者冠脉介入术后死亡的主要影响因素(P<0.05)。结论 ACS合并恶性肿瘤患者经冠脉介入治疗后死亡率较高,死亡的发生与糖尿病、吸烟、BNP水平升高、PLT减少有关,临床需予以高度重视,并针对性开展医疗干预,以最大程度改善患者预后。

妇科恶性肿瘤患者家庭复原力的潜在剖面分析

目的 基于潜在剖面分析,探讨妇科恶性肿瘤患者家庭复原力的类别特征。方法 采用一般资料调查表、家庭复原力量表、医院焦虑抑郁量表及压力知觉量表对484例妇科恶性肿瘤患者进行调查,采用一般资料调查表对其家属进行调查。结果 潜在剖面分析显示,妇科恶性肿瘤患者的家庭复原力可分为低家庭复原力组(21.07%)、中家庭复原力组(44.63%)和高家庭复原力组(34.30%)3个潜在类别。初中及以下学历、夫妻关系不佳、与其他主要家庭成员关系不佳、家属身体健康状况好及家庭分担照顾者在1人及以下者归属于低家庭复原力组的可能性更大(P<0.05)。低家庭复原力组患者的焦虑抑郁、压力知觉得分最高,高家庭复原力组的焦虑抑郁与压力知觉得分最低(P<0.05)。结论 妇科恶性肿瘤患者的家庭复原力具有明显的异质性,护理人员应根据患者家庭复原力的特征,为患者制订个性化的干预策略,提升其家庭复原力水平。