Natural mortality coefficient (M) was estimated from fish abundance (N) and catch (C) data using a Virtual Population Analysis (VPA) model. Monte Carlo simulations were used to evaluate the impact of different error d...Natural mortality coefficient (M) was estimated from fish abundance (N) and catch (C) data using a Virtual Population Analysis (VPA) model. Monte Carlo simulations were used to evaluate the impact of different error distributions for the simulated data on the estimates of M. Among the four error structures (normal, lognormal, Poisson and gamma), simulations of normally dis-tributed errors produced the most viable estimates for M, with the lowest relative estimation errors (REEs) and median mean absolute deviations (MADs) for the ratio of the true to the estimated Ms. In contrast, the lognormal distribution had the largest REE value. Errors with different coefficients of variation (CV) were added to N and C. In general, when CVs in the data were less than 10%, reliable estimates of M were obtained. For normal and lognormal distributions, the estimates of M were more sensitive to the CVs in N than in C; when only C had error the estimates were close to the true. For Poisson and gamma distributions, opposite results were obtained. For instance, the estimates were more sensitive to the CVs in C than in N, with the largest REE from the scenario of error only in C. Two scenarios of high and low fishing mortality coefficient (F) were generated, and the simulation results showed that the method performed better for the scenario with low F. This method was also applied to the published data for the anchovy (Engraulis japonicus) of the Yellow Sea. Viable estimates of M were obtained for young groups, which may be explained by the fact that the great uncertainties in N and C observed for older Yellow Sea anchovy introduced large variation in the corresponding estimates of M.展开更多
Missing data are always an issue in community-based longitudinal studies, calling into question the representativeness of samples and bias in conclusions, the research has generated. This may be due to the difficulty ...Missing data are always an issue in community-based longitudinal studies, calling into question the representativeness of samples and bias in conclusions, the research has generated. This may be due to the difficulty of implementing random sampling procedures in these studies and/or the inherent difficulty in sampling hard-to-reach segments of the population being studied. In fact, the ability to accurately study hard-to-reach populations in light of potential bias created by missing data remains an open question. In this study, missing data are defined as both failure to interview potential research participants identified in the sampling frame and failure to retain enrolled research participants longitudinally. Using the sample from the Mobile Youth Survey, a multiple-cohort, longitudinal study of adolescents living in highly impoverished neighborhoods in Mobile, Alabama, we examined sample representativeness and dropout to determine whether missing data led to a nonrepresentative, and therefore, biased sample. Results indicate that even though random procedures are not strictly used to draw the sample, (a) the sample appears to be largely representative of the population that was studied, and (b) attrition is largely uncorrelated with characteristics of those who dropped out. This suggests that it is possible to study with validity hard-to reach populations in community settings.展开更多
In studies of HIV, interval-censored data occur naturally. HIV infection time is not usually known exactly, only that it occurred before the survey, within some time interval or has not occurred at the time of the sur...In studies of HIV, interval-censored data occur naturally. HIV infection time is not usually known exactly, only that it occurred before the survey, within some time interval or has not occurred at the time of the survey. Infections are often clustered within geographical areas such as enumerator areas (EAs) and thus inducing unobserved frailty. In this paper we consider an approach for estimating parameters when infection time is unknown and assumed correlated within an EA where dependency is modeled as frailties assuming a normal distribution for frailties and a Weibull distribution for baseline hazards. The data was from a household based population survey that used a multi-stage stratified sample design to randomly select 23,275 interviewed individuals from 10,584 households of whom 15,851 interviewed individuals were further tested for HIV (crude prevalence = 9.1%). A further test conducted among those that tested HIV positive found 181 (12.5%) recently infected. Results show high degree of heterogeneity in HIV distribution between EAs translating to a modest correlation of 0.198. Intervention strategies should target geographical areas that contribute disproportionately to the epidemic of HIV. Further research needs to identify such hot spot areas and understand what factors make these areas prone to HIV.展开更多
Data User Service(DUS)offers you any data on China's population and rclated socioec onomic data--total population,age-sex composition,population density,labour force and more--to help you do demographic research,m...Data User Service(DUS)offers you any data on China's population and rclated socioec onomic data--total population,age-sex composition,population density,labour force and more--to help you do demographic research,make investments in China and so on.展开更多
Real-time monitoring and forecast of large scale active population density is of great significance as it can warn and prevent possible public safety accident caused by abnormal population aggregation.Active populatio...Real-time monitoring and forecast of large scale active population density is of great significance as it can warn and prevent possible public safety accident caused by abnormal population aggregation.Active population is defined as the number of people with their mobile phone powered on.Recently,an unfortunate deadly stampede occurred in Shanghai on December 31th 2014 causing the death of 39 people.We hope that our research can help avoid similar unfortunate accident from happening.In this paper we propose a method for active population density real-time monitoring and forecasting based on data from mobile network operators.Our method is based solely on mobile network operators existing infrastructure and barely requires extra investment,and mobile devices play a very limited role in the process of population locating.Four series forecasting methods,namely Simple Exponential Smoothing(SES),Double exponential smoothing(DES),Triple exponential smoothing(TES)and Autoregressive integrated moving average(ARIMA)are used in our experiments.Our experimental results suggest that we can achieve good forecast result for 135 min in future.展开更多
Cell population data(CPD)is regarded as the fingerprint of a blood cell at a given moment.CPD parameters harbor information associated with cell morphology and can be automatically generated using modern hematological...Cell population data(CPD)is regarded as the fingerprint of a blood cell at a given moment.CPD parameters harbor information associated with cell morphology and can be automatically generated using modern hematological analyzers.Various studies have revealed many unique clinical applications for CPD,especially for infectious diseases,such as sepsis.For example,one monocyte-related CPD parameter is the monocyte distribution width(MDW),which can be generated using a Beckman Coulter hematological analyzer.MDW has received FDA and CE approval for aiding in sepsis diagnosis in adult patients in the emergency department.Additionally,MDW can serve as a diagnostic biomarker in patients infected with SARS-CoV-2.CPD has also been widely explored for possible clinical applications beyond infectious dis-eases,such as for predicting myelodysplastic syndromes,screening for he-matological malignancies,and detecting sterile inflammation.CPD parameter measurements are easily obtained and quite cost-effective,making them practical for clinical use.However,there are some potential drawbacks of CPD parameters.Some pre-analytical conditions can affect CPD values.Further-more,CPD are specific to certain hematological analyzers and the result cannot be transferred between different analyzers.The practical usefulness of CPD reference intervals is also still questionable.In this review,wesummarize the current studies related to CPD and its clinical applications.Additional well-designed clinical studies related to CPD are still expected.展开更多
To clarify the recent trends in prostate-specific antigen (PSA) distribution in men in Japan, we analyzed the PSA distributions of men undergoing PSA-based population screening. We summarized the annual individual d...To clarify the recent trends in prostate-specific antigen (PSA) distribution in men in Japan, we analyzed the PSA distributions of men undergoing PSA-based population screening. We summarized the annual individual data of PSA-based population screening in Kanazawa, Japan, from 2000 to 2011, and analyzed baseline serum PSA values of the participants at the first population screening. Serum PSA distributions were estimated in all participants and those excluding prostate cancer patients according to age. From 2000 to 2011, 19 620 men participated aged 54-69 years old in this screening program. Mean baseline serum PSA level of all participants at the first screening was 2.64 ng m1-1 in 2000, and gradually decreased to approximately 1.30 ng ml-I in 2006. That of participants excluding prostate cancer patients was 1.46 ng m1-1 in 2000, and there was no remarkable change during the study period. The 95t" percentiles in the participants excluding prostate cancer patients detected at the first population screening of men aged 54-59, 60-64, and 65-69 years old were 2.90, 3.60, and 4.50 ng m1-1, respectively. After the commencement of population screening, the proportion of prostate cancer patients with high serum PSA levels decreased. However, there were no changes in serum PSA levels in men without prostate cancer. Age-specific PSA reference level of men without prostate cancer in Japan was similar to that in China and Korea.展开更多
Although China’s urban floating population is mainly concentrated in developed cities,from the central and western cities to the eastern developed cities,but the characteristics of the floating population in differen...Although China’s urban floating population is mainly concentrated in developed cities,from the central and western cities to the eastern developed cities,but the characteristics of the floating population in different cities are significantly different.This paper systematically investigates the spatiotemporal characteristics and influencing factors of the floating population in different levels of cities.The results show that the regional imbalance to further strengthen,accumulation and dispersion trend has become increasingly obvious,liquidity is positively correlated and city level scale,and urban agglomeration and the core city is still polarization center of floating population.Flow range is closely related to urban hierarchy:the higher the intra-urban grade,the more tend to inter-provincial flow;the lower the city grade,the more tend to intra-urban mobility.Short-term(1-2 years)and long-term(more than 7 years)flow-time coexist.The short-term liquidity increases with the city grade,and the long-term liquidity decreases with the city level.Farmers are still the main body of the floating population.Younger age,lower education level,low-skilled,high gender ratio employees are the most basic demographic characteristics of the floating population,although there are differences between different cities.The main reason for affecting the floating population is seeking jobs and doing business.展开更多
Bayesian predictive probability density function is obtained when the underlying pop-ulation distribution is exponentiated and subjective prior is used. The corresponding predictive survival function is then obtained ...Bayesian predictive probability density function is obtained when the underlying pop-ulation distribution is exponentiated and subjective prior is used. The corresponding predictive survival function is then obtained and used in constructing 100(1 – ?)% predictive interval, using one- and two- sample schemes when the size of the future sample is fixed and random. In the random case, the size of the future sample is assumed to follow the truncated Poisson distribution with parameter λ. Special attention is paid to the exponentiated Burr type XII population, from which the data are drawn. Two illustrative examples are given, one of which uses simulated data and the other uses data that represent the breaking strength of 64 single carbon fibers of length 10, found in Lawless [40].展开更多
With the continuous development of urbanization in China,the country’s growing population brings great challenges to urban development.By mastering the refined population spatial distribution in administrative units,...With the continuous development of urbanization in China,the country’s growing population brings great challenges to urban development.By mastering the refined population spatial distribution in administrative units,the quantity and agglomeration of population distribution can be estimated and visualized.It will provide a basis for a more rational urban planning.This paper takes Beijing as the research area and uses a new Luojia1-01 nighttime light image with high resolution,land use type data,Points of Interest(POI)data,and other data to construct the population spatial index system,establishing the index weight based on the principal component analysis.The comprehensive weight value of population distribution in the study area was then used to calculate the street population distribution of Beijing in 2018.Then the population spatial distribution was visualize using GIS technology.After accuracy assessments by comparing the result with the WorldPop data,the accuracy has reached 0.74.The proposed method was validated as a qualified method to generate population spatial maps.By contrast of local areas,Luojia 1-01 data is more suitable for population distribution estimation than the NPP/VIIRS(Net Primary Productivity/Visible infrared Imaging Radiometer)nighttime light data.More geospatial big data and mathematical models can be combined to create more accurate population maps in the future.展开更多
目的旨在建立南京地区不同年龄和性别表观健康成年人白细胞群落参数的参考区间。方法选择2024年1月至4月于南京大学医学院附属鼓楼医院进行体检的1262名健康成人作为研究对象。采用Sysmex XN全自动血细胞分析仪进行血常规检测,同时记录...目的旨在建立南京地区不同年龄和性别表观健康成年人白细胞群落参数的参考区间。方法选择2024年1月至4月于南京大学医学院附属鼓楼医院进行体检的1262名健康成人作为研究对象。采用Sysmex XN全自动血细胞分析仪进行血常规检测,同时记录仪器WDF通道提供的中性粒、淋巴和单核细胞相关的细胞群落参数(cell population data,CPD),统称为白细胞CPD,包括它们的平均侧向散射光强度(NE-SSC、LY-X、MO-X)和分布宽度(NE-WX、LY-WX、MO-WY);平均荧光强度(NE-SFL、LY-Y、MO-Y)和分布宽度(NE-WY、LY-WY、MO-WY);平均前向散射光强度(NE-FSC、LY-Z、MO-Z)和分布宽度(NE-WZ、LY-WZ、MO-WZ)。参照中华人民共和国卫生行业标准(WS/T405-2012)《血细胞分析参考区间》中的推荐方法,分析各项指标在不同年龄及性别间的差异,并得出南京健康成人白细胞CPD的参考区间。结果在男女两性别组内按年龄分组比较发现,LY-WZ、MO-WZ、NE-FCS、NE-WZ不显示年龄和性别上的差异;MO-Z只显示性别差异;LY-Y、LY-Z、MO-X、NE-SSC、NE-WY只在女性组内存在年龄差异;MO-WY、MO-Y、NE-SFL、NE-WX只在男性内存在年龄差异;LY-X、LY-WX、LY-WY、MO-WX在两性别组内均存在年龄差异。以此为依据划分参考区间。结论建立了南京地区白细胞CPD在不同性别和年龄段健康成年人中的参考区间,为疾病的诊断、治疗和预后判断提供重要的实验室参考依据。展开更多
文摘Natural mortality coefficient (M) was estimated from fish abundance (N) and catch (C) data using a Virtual Population Analysis (VPA) model. Monte Carlo simulations were used to evaluate the impact of different error distributions for the simulated data on the estimates of M. Among the four error structures (normal, lognormal, Poisson and gamma), simulations of normally dis-tributed errors produced the most viable estimates for M, with the lowest relative estimation errors (REEs) and median mean absolute deviations (MADs) for the ratio of the true to the estimated Ms. In contrast, the lognormal distribution had the largest REE value. Errors with different coefficients of variation (CV) were added to N and C. In general, when CVs in the data were less than 10%, reliable estimates of M were obtained. For normal and lognormal distributions, the estimates of M were more sensitive to the CVs in N than in C; when only C had error the estimates were close to the true. For Poisson and gamma distributions, opposite results were obtained. For instance, the estimates were more sensitive to the CVs in C than in N, with the largest REE from the scenario of error only in C. Two scenarios of high and low fishing mortality coefficient (F) were generated, and the simulation results showed that the method performed better for the scenario with low F. This method was also applied to the published data for the anchovy (Engraulis japonicus) of the Yellow Sea. Viable estimates of M were obtained for young groups, which may be explained by the fact that the great uncertainties in N and C observed for older Yellow Sea anchovy introduced large variation in the corresponding estimates of M.
文摘Missing data are always an issue in community-based longitudinal studies, calling into question the representativeness of samples and bias in conclusions, the research has generated. This may be due to the difficulty of implementing random sampling procedures in these studies and/or the inherent difficulty in sampling hard-to-reach segments of the population being studied. In fact, the ability to accurately study hard-to-reach populations in light of potential bias created by missing data remains an open question. In this study, missing data are defined as both failure to interview potential research participants identified in the sampling frame and failure to retain enrolled research participants longitudinally. Using the sample from the Mobile Youth Survey, a multiple-cohort, longitudinal study of adolescents living in highly impoverished neighborhoods in Mobile, Alabama, we examined sample representativeness and dropout to determine whether missing data led to a nonrepresentative, and therefore, biased sample. Results indicate that even though random procedures are not strictly used to draw the sample, (a) the sample appears to be largely representative of the population that was studied, and (b) attrition is largely uncorrelated with characteristics of those who dropped out. This suggests that it is possible to study with validity hard-to reach populations in community settings.
文摘In studies of HIV, interval-censored data occur naturally. HIV infection time is not usually known exactly, only that it occurred before the survey, within some time interval or has not occurred at the time of the survey. Infections are often clustered within geographical areas such as enumerator areas (EAs) and thus inducing unobserved frailty. In this paper we consider an approach for estimating parameters when infection time is unknown and assumed correlated within an EA where dependency is modeled as frailties assuming a normal distribution for frailties and a Weibull distribution for baseline hazards. The data was from a household based population survey that used a multi-stage stratified sample design to randomly select 23,275 interviewed individuals from 10,584 households of whom 15,851 interviewed individuals were further tested for HIV (crude prevalence = 9.1%). A further test conducted among those that tested HIV positive found 181 (12.5%) recently infected. Results show high degree of heterogeneity in HIV distribution between EAs translating to a modest correlation of 0.198. Intervention strategies should target geographical areas that contribute disproportionately to the epidemic of HIV. Further research needs to identify such hot spot areas and understand what factors make these areas prone to HIV.
文摘Data User Service(DUS)offers you any data on China's population and rclated socioec onomic data--total population,age-sex composition,population density,labour force and more--to help you do demographic research,make investments in China and so on.
文摘Real-time monitoring and forecast of large scale active population density is of great significance as it can warn and prevent possible public safety accident caused by abnormal population aggregation.Active population is defined as the number of people with their mobile phone powered on.Recently,an unfortunate deadly stampede occurred in Shanghai on December 31th 2014 causing the death of 39 people.We hope that our research can help avoid similar unfortunate accident from happening.In this paper we propose a method for active population density real-time monitoring and forecasting based on data from mobile network operators.Our method is based solely on mobile network operators existing infrastructure and barely requires extra investment,and mobile devices play a very limited role in the process of population locating.Four series forecasting methods,namely Simple Exponential Smoothing(SES),Double exponential smoothing(DES),Triple exponential smoothing(TES)and Autoregressive integrated moving average(ARIMA)are used in our experiments.Our experimental results suggest that we can achieve good forecast result for 135 min in future.
基金the basic and applied basic research projects of Guangdong Province,Grant/Award Number:2021A1515220040。
文摘Cell population data(CPD)is regarded as the fingerprint of a blood cell at a given moment.CPD parameters harbor information associated with cell morphology and can be automatically generated using modern hematological analyzers.Various studies have revealed many unique clinical applications for CPD,especially for infectious diseases,such as sepsis.For example,one monocyte-related CPD parameter is the monocyte distribution width(MDW),which can be generated using a Beckman Coulter hematological analyzer.MDW has received FDA and CE approval for aiding in sepsis diagnosis in adult patients in the emergency department.Additionally,MDW can serve as a diagnostic biomarker in patients infected with SARS-CoV-2.CPD has also been widely explored for possible clinical applications beyond infectious dis-eases,such as for predicting myelodysplastic syndromes,screening for he-matological malignancies,and detecting sterile inflammation.CPD parameter measurements are easily obtained and quite cost-effective,making them practical for clinical use.However,there are some potential drawbacks of CPD parameters.Some pre-analytical conditions can affect CPD values.Further-more,CPD are specific to certain hematological analyzers and the result cannot be transferred between different analyzers.The practical usefulness of CPD reference intervals is also still questionable.In this review,wesummarize the current studies related to CPD and its clinical applications.Additional well-designed clinical studies related to CPD are still expected.
文摘To clarify the recent trends in prostate-specific antigen (PSA) distribution in men in Japan, we analyzed the PSA distributions of men undergoing PSA-based population screening. We summarized the annual individual data of PSA-based population screening in Kanazawa, Japan, from 2000 to 2011, and analyzed baseline serum PSA values of the participants at the first population screening. Serum PSA distributions were estimated in all participants and those excluding prostate cancer patients according to age. From 2000 to 2011, 19 620 men participated aged 54-69 years old in this screening program. Mean baseline serum PSA level of all participants at the first screening was 2.64 ng m1-1 in 2000, and gradually decreased to approximately 1.30 ng ml-I in 2006. That of participants excluding prostate cancer patients was 1.46 ng m1-1 in 2000, and there was no remarkable change during the study period. The 95t" percentiles in the participants excluding prostate cancer patients detected at the first population screening of men aged 54-59, 60-64, and 65-69 years old were 2.90, 3.60, and 4.50 ng m1-1, respectively. After the commencement of population screening, the proportion of prostate cancer patients with high serum PSA levels decreased. However, there were no changes in serum PSA levels in men without prostate cancer. Age-specific PSA reference level of men without prostate cancer in Japan was similar to that in China and Korea.
文摘Although China’s urban floating population is mainly concentrated in developed cities,from the central and western cities to the eastern developed cities,but the characteristics of the floating population in different cities are significantly different.This paper systematically investigates the spatiotemporal characteristics and influencing factors of the floating population in different levels of cities.The results show that the regional imbalance to further strengthen,accumulation and dispersion trend has become increasingly obvious,liquidity is positively correlated and city level scale,and urban agglomeration and the core city is still polarization center of floating population.Flow range is closely related to urban hierarchy:the higher the intra-urban grade,the more tend to inter-provincial flow;the lower the city grade,the more tend to intra-urban mobility.Short-term(1-2 years)and long-term(more than 7 years)flow-time coexist.The short-term liquidity increases with the city grade,and the long-term liquidity decreases with the city level.Farmers are still the main body of the floating population.Younger age,lower education level,low-skilled,high gender ratio employees are the most basic demographic characteristics of the floating population,although there are differences between different cities.The main reason for affecting the floating population is seeking jobs and doing business.
文摘Bayesian predictive probability density function is obtained when the underlying pop-ulation distribution is exponentiated and subjective prior is used. The corresponding predictive survival function is then obtained and used in constructing 100(1 – ?)% predictive interval, using one- and two- sample schemes when the size of the future sample is fixed and random. In the random case, the size of the future sample is assumed to follow the truncated Poisson distribution with parameter λ. Special attention is paid to the exponentiated Burr type XII population, from which the data are drawn. Two illustrative examples are given, one of which uses simulated data and the other uses data that represent the breaking strength of 64 single carbon fibers of length 10, found in Lawless [40].
基金Under the auspices of Natural Science Foundation of China(No.42071342,31870713)Beijing Natural Science Foundation Program(No.8182038)Fundamental Research Funds for the Central Universities(No.2015ZCQ-LX-01,2018ZY06)。
文摘With the continuous development of urbanization in China,the country’s growing population brings great challenges to urban development.By mastering the refined population spatial distribution in administrative units,the quantity and agglomeration of population distribution can be estimated and visualized.It will provide a basis for a more rational urban planning.This paper takes Beijing as the research area and uses a new Luojia1-01 nighttime light image with high resolution,land use type data,Points of Interest(POI)data,and other data to construct the population spatial index system,establishing the index weight based on the principal component analysis.The comprehensive weight value of population distribution in the study area was then used to calculate the street population distribution of Beijing in 2018.Then the population spatial distribution was visualize using GIS technology.After accuracy assessments by comparing the result with the WorldPop data,the accuracy has reached 0.74.The proposed method was validated as a qualified method to generate population spatial maps.By contrast of local areas,Luojia 1-01 data is more suitable for population distribution estimation than the NPP/VIIRS(Net Primary Productivity/Visible infrared Imaging Radiometer)nighttime light data.More geospatial big data and mathematical models can be combined to create more accurate population maps in the future.
文摘目的旨在建立南京地区不同年龄和性别表观健康成年人白细胞群落参数的参考区间。方法选择2024年1月至4月于南京大学医学院附属鼓楼医院进行体检的1262名健康成人作为研究对象。采用Sysmex XN全自动血细胞分析仪进行血常规检测,同时记录仪器WDF通道提供的中性粒、淋巴和单核细胞相关的细胞群落参数(cell population data,CPD),统称为白细胞CPD,包括它们的平均侧向散射光强度(NE-SSC、LY-X、MO-X)和分布宽度(NE-WX、LY-WX、MO-WY);平均荧光强度(NE-SFL、LY-Y、MO-Y)和分布宽度(NE-WY、LY-WY、MO-WY);平均前向散射光强度(NE-FSC、LY-Z、MO-Z)和分布宽度(NE-WZ、LY-WZ、MO-WZ)。参照中华人民共和国卫生行业标准(WS/T405-2012)《血细胞分析参考区间》中的推荐方法,分析各项指标在不同年龄及性别间的差异,并得出南京健康成人白细胞CPD的参考区间。结果在男女两性别组内按年龄分组比较发现,LY-WZ、MO-WZ、NE-FCS、NE-WZ不显示年龄和性别上的差异;MO-Z只显示性别差异;LY-Y、LY-Z、MO-X、NE-SSC、NE-WY只在女性组内存在年龄差异;MO-WY、MO-Y、NE-SFL、NE-WX只在男性内存在年龄差异;LY-X、LY-WX、LY-WY、MO-WX在两性别组内均存在年龄差异。以此为依据划分参考区间。结论建立了南京地区白细胞CPD在不同性别和年龄段健康成年人中的参考区间,为疾病的诊断、治疗和预后判断提供重要的实验室参考依据。