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Aggregation-based analytical chemistry in point-of-care nanosensors
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作者 Yuechun Li Zhaowen Cui +4 位作者 Lunjie Huang Daohong Zhang Yizhong Shen Jie Cheng Jianlong Wang 《Aggregate》 EI CAS 2024年第5期23-85,共63页
It is crucial to realize the point-of-care(POC)testing of harmful analytes,capa-ble of saving limited agricultural resources,assisting environmental remediation,ensuring food safety,and enabling early disease diagnosi... It is crucial to realize the point-of-care(POC)testing of harmful analytes,capa-ble of saving limited agricultural resources,assisting environmental remediation,ensuring food safety,and enabling early disease diagnosis.Compared with other conventional POC sensing strategies,aggregation-based analytical chemistry facil-itates the practical-oriented development of POC nanosensors by altering the aggregation status of nanoprobes through the action of multiple aggregation-induced“forces”originating from the targets.Herein,we have proceeded with a comprehensive review focusing on the aggregation-based analytical chemistry in POC nanosensors,covering aggregation-induced“forces”,aggregation-induced signal transductions,aggregation-induced POC nanosensing strategies,and their applications in biomolecular monitoring,food safety analysis,and environmental monitoring.Finally,challenges existing in practical applications have been fur-ther proposed to improve their sensing applications,and we expect our review can speed up the development of cost-effective,readily deployable,and time-efficient nanosensors through aggregation-based analytical chemistry. 展开更多
关键词 aggregation-based analytical chemistry biomolecular monitoring environmental monitoring food safety analysis point-of-care nanosensors
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