计算机辅助药物分子设计是现代药物化学研究的重要组成部分,在学术和工业界具有广泛的应用前景。近年来涌现的众多在线工具能够为药物设计教学带来便捷。本文介绍了一系列优秀的免费在线工具,包括Swiss Drug Design、Cavity Plus、Pharm...计算机辅助药物分子设计是现代药物化学研究的重要组成部分,在学术和工业界具有广泛的应用前景。近年来涌现的众多在线工具能够为药物设计教学带来便捷。本文介绍了一系列优秀的免费在线工具,包括Swiss Drug Design、Cavity Plus、Pharm Mapper和ADMETlab,探讨它们在药物分子设计课程中的应用。以环氧合酶2及其抑制剂吲哚美辛为案例,详细展示如何利用这些工具进行药物设计实践。所述方法不仅适用于理论课程的教学演示,还可用于实验课程的实际操作,并可为学生的创新课题研究提供指导。展开更多
The development of social work is to some extent a history of the struggle against poverty. Social work enabled targeted poverty alleviation aims to form a two–way force to implement targeted poverty alleviation poli...The development of social work is to some extent a history of the struggle against poverty. Social work enabled targeted poverty alleviation aims to form a two–way force to implement targeted poverty alleviation policies in a bid to create a new situation featuring top–down policy guidance and bottom–up social engagement. Social work enabled targeted poverty alleviation addresses the bureaucratic defects of government dominance, upgrades the narrow conception of targeted poverty alleviation as individual aid, and pays more attention to the interactions between the poor and environmental elements and the interactions within and between systems from the perspective of eco–system. In practice, this type of poverty alleviation is manifested as social work driven integral specialized poverty alleviation. By organically combining the four systems of subjects, service objects, work processes and implementation results, it advances current targeted poverty alleviation from the mid–shallow level to the deep level. It is expected to fulfill the intrinsic policy objectives of targeted poverty alleviation and explore a supporting system for realizing the modernization of national governance system and capacity in rural areas.展开更多
文摘计算机辅助药物分子设计是现代药物化学研究的重要组成部分,在学术和工业界具有广泛的应用前景。近年来涌现的众多在线工具能够为药物设计教学带来便捷。本文介绍了一系列优秀的免费在线工具,包括Swiss Drug Design、Cavity Plus、Pharm Mapper和ADMETlab,探讨它们在药物分子设计课程中的应用。以环氧合酶2及其抑制剂吲哚美辛为案例,详细展示如何利用这些工具进行药物设计实践。所述方法不仅适用于理论课程的教学演示,还可用于实验课程的实际操作,并可为学生的创新课题研究提供指导。
基金staged research result of "Studies on social work enabled targeted poverty alleviation in linked poverty–stricken regions of northwest China"(16YJA840003)2016 program funded by the Research Base of Humanities and Social Sciences under the Ministry of Education of the PRC
文摘The development of social work is to some extent a history of the struggle against poverty. Social work enabled targeted poverty alleviation aims to form a two–way force to implement targeted poverty alleviation policies in a bid to create a new situation featuring top–down policy guidance and bottom–up social engagement. Social work enabled targeted poverty alleviation addresses the bureaucratic defects of government dominance, upgrades the narrow conception of targeted poverty alleviation as individual aid, and pays more attention to the interactions between the poor and environmental elements and the interactions within and between systems from the perspective of eco–system. In practice, this type of poverty alleviation is manifested as social work driven integral specialized poverty alleviation. By organically combining the four systems of subjects, service objects, work processes and implementation results, it advances current targeted poverty alleviation from the mid–shallow level to the deep level. It is expected to fulfill the intrinsic policy objectives of targeted poverty alleviation and explore a supporting system for realizing the modernization of national governance system and capacity in rural areas.
