Background: Flight and cabin crew are known to be at increased risk for atherosclerotic cardiovascular disease (ASCVD). However, ASCVD risks have not yet been compared in flight and cabin crew in low resource settings...Background: Flight and cabin crew are known to be at increased risk for atherosclerotic cardiovascular disease (ASCVD). However, ASCVD risks have not yet been compared in flight and cabin crew in low resource settings like sub-Saharan Africa. Objectives: To assess absolute ASCVD risk estimate and its clinical correlates among flight and cabin crew. Methods: From June 1st 2015 to December 30th 2015, 379 consecutive aviation navigants (Flight crew: 62.5%, pilots: 46.2%, women: 29.6%, Caucasians 23.2%) were enrolled in a cross-sectional survey of ASCVD risk estimate using the Framingham tools. They underwent a physical examination for either initial or renewal medical certificate Class 1 or 2 including blood chemistry, ECG, and echocardiogram as per International Civil Aviation Organization (ICAO) and Civil Aviation Authority (CAA-DRC) medical regulations. We modeled the risk of moderate and high ASCVD estimate in a stepwise logistic regression. Results: Low, moderate and high ASCVD risk estimates were observed respectively in 248 (65.4%), 64 (16.9%), and 67 (17.7%) navigants. Moderate and high ASCVD risk estimates predominated among flight than cabin crew (23.6% vs. 5.6%;p 0.0001 and 28.3% vs. null;p 0.001), low ASCVD risk estimate among cabin than flight crew (94.4% vs. 48.1%;p ≤ 0.001). Low ASCVD risk?estimates.展开更多
This study looks into the influence of cosmic radiation at high altitudes on human bodies. Results reveal that the cytokinesis-block micronuclei (CBMN) and conventional cultured micronuclei in peripheral blood lymphoc...This study looks into the influence of cosmic radiation at high altitudes on human bodies. Results reveal that the cytokinesis-block micronuclei (CBMN) and conventional cultured micronuclei in peripheral blood lymphocytes, serum levels of lipid peroxide, superoxide dismutase, and the total antioxidation capacity by chemical colorimetry all increased significantly in aircrew members. There exists a linear relationship between the CBMN and the average annual effective doses of radiation received or the average annual flying hours. With both of them, a trend shows that the serum lipid peroxide levels increase as well. Either the lipid peroxide or CBMN can sensitively reflect the recent changes in flight load. These findings indicate that cosmic radiation impairs the stability of chromosomes and genome, and induces lipid oxidative damage in aircrews; Lymphocyte CBMN and serum lipid peroxide can be used as monitoring indicators in the cosmic radiation protection for aircrew members.展开更多
目的报道1例飞行人员无明确传染源感染布鲁氏菌病并复习相关文献,旨在提高对布鲁氏菌病的诊疗水平。方法回顾性分析1例无明确传染源的发热飞行人员感染布氏菌病的病历资料,综合相关数据库(中国知网、中华医学期刊数据库、Web of Science...目的报道1例飞行人员无明确传染源感染布鲁氏菌病并复习相关文献,旨在提高对布鲁氏菌病的诊疗水平。方法回顾性分析1例无明确传染源的发热飞行人员感染布氏菌病的病历资料,综合相关数据库(中国知网、中华医学期刊数据库、Web of Science及PubMed数据库)文献结果,总结飞行人员感染布氏杆菌情况。结果本例为41岁男性飞行人员,无明显诱因发热、出汗,测体温波动于37.6℃~39.6℃,近1个月出现午后发热,伴畏寒、乏力,经反复血培养,布鲁氏杆菌凝集试验阳性,虎红平板凝集试验(+)。给予治疗,地面观察期满,综合各专家意见,给予飞行合格结论。检索数据库共有3篇文献是关于飞行人员布氏菌病感染。结论对于此前罹患过布氏菌病的飞行人员应进行复查,单位要分离牲畜及厨余垃圾,从源头上减少飞行人员感染布鲁氏菌病的机会。展开更多
文摘Background: Flight and cabin crew are known to be at increased risk for atherosclerotic cardiovascular disease (ASCVD). However, ASCVD risks have not yet been compared in flight and cabin crew in low resource settings like sub-Saharan Africa. Objectives: To assess absolute ASCVD risk estimate and its clinical correlates among flight and cabin crew. Methods: From June 1st 2015 to December 30th 2015, 379 consecutive aviation navigants (Flight crew: 62.5%, pilots: 46.2%, women: 29.6%, Caucasians 23.2%) were enrolled in a cross-sectional survey of ASCVD risk estimate using the Framingham tools. They underwent a physical examination for either initial or renewal medical certificate Class 1 or 2 including blood chemistry, ECG, and echocardiogram as per International Civil Aviation Organization (ICAO) and Civil Aviation Authority (CAA-DRC) medical regulations. We modeled the risk of moderate and high ASCVD estimate in a stepwise logistic regression. Results: Low, moderate and high ASCVD risk estimates were observed respectively in 248 (65.4%), 64 (16.9%), and 67 (17.7%) navigants. Moderate and high ASCVD risk estimates predominated among flight than cabin crew (23.6% vs. 5.6%;p 0.0001 and 28.3% vs. null;p 0.001), low ASCVD risk estimate among cabin than flight crew (94.4% vs. 48.1%;p ≤ 0.001). Low ASCVD risk?estimates.
基金This work was supported by the Science Foundation of Civil Aviation Administration of China (Grant No. 99-3-3).
文摘This study looks into the influence of cosmic radiation at high altitudes on human bodies. Results reveal that the cytokinesis-block micronuclei (CBMN) and conventional cultured micronuclei in peripheral blood lymphocytes, serum levels of lipid peroxide, superoxide dismutase, and the total antioxidation capacity by chemical colorimetry all increased significantly in aircrew members. There exists a linear relationship between the CBMN and the average annual effective doses of radiation received or the average annual flying hours. With both of them, a trend shows that the serum lipid peroxide levels increase as well. Either the lipid peroxide or CBMN can sensitively reflect the recent changes in flight load. These findings indicate that cosmic radiation impairs the stability of chromosomes and genome, and induces lipid oxidative damage in aircrews; Lymphocyte CBMN and serum lipid peroxide can be used as monitoring indicators in the cosmic radiation protection for aircrew members.
文摘目的报道1例飞行人员无明确传染源感染布鲁氏菌病并复习相关文献,旨在提高对布鲁氏菌病的诊疗水平。方法回顾性分析1例无明确传染源的发热飞行人员感染布氏菌病的病历资料,综合相关数据库(中国知网、中华医学期刊数据库、Web of Science及PubMed数据库)文献结果,总结飞行人员感染布氏杆菌情况。结果本例为41岁男性飞行人员,无明显诱因发热、出汗,测体温波动于37.6℃~39.6℃,近1个月出现午后发热,伴畏寒、乏力,经反复血培养,布鲁氏杆菌凝集试验阳性,虎红平板凝集试验(+)。给予治疗,地面观察期满,综合各专家意见,给予飞行合格结论。检索数据库共有3篇文献是关于飞行人员布氏菌病感染。结论对于此前罹患过布氏菌病的飞行人员应进行复查,单位要分离牲畜及厨余垃圾,从源头上减少飞行人员感染布鲁氏菌病的机会。
