To study the chemical constituents,the ethanol extract of dried stem of Akebia quinata(Thunb.) Decne.was seperated by dichloromethane,n-butanol in sequence.The n-butanol extract was further isolated by D101 macroporou...To study the chemical constituents,the ethanol extract of dried stem of Akebia quinata(Thunb.) Decne.was seperated by dichloromethane,n-butanol in sequence.The n-butanol extract was further isolated by D101 macroporous resin and silica gel column chromatography.A new triterpene with two known triterpenes were isolated,their structures were identified as 3α,24-dihydroxy-30-norolean-12,20(29)-dien-28-oic acid(Ⅰ),3α,24,29-trihydroxyolean-12-en-28-oic acid(Ⅱ),2α,3β,23-trihydroxyolean-12-en-28-oic acid(Ⅲ).The new compound Ⅱ was nominated as quinatic stem acid.The structures were identified and elucidated by physicochemical properties and spectral analysis.展开更多
Two new triterpenoid saponins, hederagenin 3-O-α-L-arabinopyranosyl-（1→〉2）-α-L-arabinopyranoside named akeboside La （compound 1）, oleanolic acid 3-O-α-L-arabinopyranosyl-（1→〉2）-β-D-glucopyranoside named ...Two new triterpenoid saponins, hederagenin 3-O-α-L-arabinopyranosyl-（1→〉2）-α-L-arabinopyranoside named akeboside La （compound 1）, oleanolic acid 3-O-α-L-arabinopyranosyl-（1→〉2）-β-D-glucopyranoside named akeboside Lb （compound 2）, along with five known saponins, oleanolic acid 3-O-α-L-rhamnopyranosyl-（1→〉2）-α-L- arabinopyranoside （compound 3）, hederagenin 3-O-α-L-rhamnopyranosyl-（1→〉2）-α-L-arabinopyranoside （compound 4）, oleanolic acid 3-O-β-D-xylopyranosyl-（1→〉3）-α-L-rhamnopyranosyl-（1→〉2）-α-L-arabinopyranoside （compound 5）, 3-O-α-L-rhamnopyranosyl-（1→〉2）-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl-（1→〉4）-α-D- glucopyranosyl-（1→〉6）-β-D-glucopyranoside （compound 6）, 3-O-α-L-rhamnopyranosyl-（1→〉2）-α-L-arabinopyranosyl hederagenin 28-α-L-rhamnopyranosyl-（1→〉4）-β-D-glucopyranosyl-（1→〉6）-β-D-glucopyranoside （compound 7） were isolated from the n-butanol part of the 80% ethanol extracts of the dried stems of Akebia quinata （Thunb.） Decne. Compound 5 was isolated from plants of genus Akebia for the first time. The structures were elucidated on the basis of physicochemical properties and spectral data.展开更多
文摘To study the chemical constituents,the ethanol extract of dried stem of Akebia quinata(Thunb.) Decne.was seperated by dichloromethane,n-butanol in sequence.The n-butanol extract was further isolated by D101 macroporous resin and silica gel column chromatography.A new triterpene with two known triterpenes were isolated,their structures were identified as 3α,24-dihydroxy-30-norolean-12,20(29)-dien-28-oic acid(Ⅰ),3α,24,29-trihydroxyolean-12-en-28-oic acid(Ⅱ),2α,3β,23-trihydroxyolean-12-en-28-oic acid(Ⅲ).The new compound Ⅱ was nominated as quinatic stem acid.The structures were identified and elucidated by physicochemical properties and spectral analysis.
文摘Two new triterpenoid saponins, hederagenin 3-O-α-L-arabinopyranosyl-（1→〉2）-α-L-arabinopyranoside named akeboside La （compound 1）, oleanolic acid 3-O-α-L-arabinopyranosyl-（1→〉2）-β-D-glucopyranoside named akeboside Lb （compound 2）, along with five known saponins, oleanolic acid 3-O-α-L-rhamnopyranosyl-（1→〉2）-α-L- arabinopyranoside （compound 3）, hederagenin 3-O-α-L-rhamnopyranosyl-（1→〉2）-α-L-arabinopyranoside （compound 4）, oleanolic acid 3-O-β-D-xylopyranosyl-（1→〉3）-α-L-rhamnopyranosyl-（1→〉2）-α-L-arabinopyranoside （compound 5）, 3-O-α-L-rhamnopyranosyl-（1→〉2）-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl-（1→〉4）-α-D- glucopyranosyl-（1→〉6）-β-D-glucopyranoside （compound 6）, 3-O-α-L-rhamnopyranosyl-（1→〉2）-α-L-arabinopyranosyl hederagenin 28-α-L-rhamnopyranosyl-（1→〉4）-β-D-glucopyranosyl-（1→〉6）-β-D-glucopyranoside （compound 7） were isolated from the n-butanol part of the 80% ethanol extracts of the dried stems of Akebia quinata （Thunb.） Decne. Compound 5 was isolated from plants of genus Akebia for the first time. The structures were elucidated on the basis of physicochemical properties and spectral data.
