[Objectives]This study aimed to investigate the intervention effects of ethanol extract of Laggera alata(D.Don)Sch.Bip.ex Oliv on cirrhotic rats with ascites.[Methods]A total of 100 male SD rats of SPF grade were used...[Objectives]This study aimed to investigate the intervention effects of ethanol extract of Laggera alata(D.Don)Sch.Bip.ex Oliv on cirrhotic rats with ascites.[Methods]A total of 100 male SD rats of SPF grade were used.Rat models of cirrhosis and ascites were established.After the last administration,the amount of peritoneal fluid was measured,and the blood of each rat tested was collected for determination of serum AST,ALT and ALB levels,serum K+concentration and plasma Ald level.[Results]In ascitic cirrhotic rats,the livers showed obvious enlargement,the surface of the livers was uneven,and nodules were visible.Compared with the blank group,the amount of peritoneal fluid in the model group increased significantly(P<0.01);and compared with the model group,the amounts of peritoneal fluid in the high and medium-dose ethanol extract groups reduced significantly(P<0.01).Compared with the blank group,the serum ALT and AST levels in the model group increased significantly(P<0.01);and compared with the model group,the serum ALT and AST levels in the high-dose ethanol extract group decreased significantly(P<0.05).Compared with the blank group,the serum K+concentration in the positive group reduced(P<0.05);no significant difference was found in serum K+concentration between the ethanol extract administration groups and the blank group(P>0.05).Compared with the blank group,the plasma Ald levels in the high-dose ethanol extract group and the positive group reduced(P<0.05);and there was no significant difference in serum K+concentration between the rest groups and the blank group(P>0.05).[Conclusions]In the ethanol extract administration groups,the amounts of peritoneal fluid significantly reduced,the serum ALT and AST reduced,and the liver functions improved to a certain extent,indicating that the ethanol extract of L.alata(D.Don)Sch.Bip.ex Oliv has a better correction effect on electrolyte disturbances in cirrhotic rats with ascites.展开更多
[Objective] The aim was to study the effect of different treatments on development and growth of Halenia ellipitica D.Don.[Method] Three treatments (urea treatment group, diammonium phosphate treatment group and contr...[Objective] The aim was to study the effect of different treatments on development and growth of Halenia ellipitica D.Don.[Method] Three treatments (urea treatment group, diammonium phosphate treatment group and control group) were set in the experiment with 3 replications to detect plant height,root length, leaf number, branch number, flower number and biomass of Halenia ellipitica D.Don. in all experimental groups.[Result] The leaf number,branch number, flower number and output of crude drug of Halenia ellipitica D.Don. in urea treatment group were more than that of Halenia ellipitica D.Don. in diammonium phosphate treatment group and control group,however,the plant height and root length were not significantly different among all groups.[Conclusion] The urea generated better effect on Halenia ellipitica D.Don. cultivation than that produced by diammonium phosphate treatment.展开更多
A new phenolic constituent along with five known compounds were isolated from Fagopyrum dibotrys (D.Don) Hara. The new compound was characterized as 1,3-dimethoxy-2-O-β-xylo-pyranosyl-5-O-β-glucopyranosyl-benzene, b...A new phenolic constituent along with five known compounds were isolated from Fagopyrum dibotrys (D.Don) Hara. The new compound was characterized as 1,3-dimethoxy-2-O-β-xylo-pyranosyl-5-O-β-glucopyranosyl-benzene, by spectroscopic analysis and enzymatic hydrolysis.展开更多
[Objectives] To establish a method for determining the content of Laggera alata( D. Don) Sch. Bip. Ex Oliv. using caffeic acid the target component,and to compare the content of caffeic acid in the medicinal materials...[Objectives] To establish a method for determining the content of Laggera alata( D. Don) Sch. Bip. Ex Oliv. using caffeic acid the target component,and to compare the content of caffeic acid in the medicinal materials of L. alata in different production areas of Guangxi.[Methods]The content was determined by Inertsil~ODS-3 chromatographic column C_(18)( 4. 60 mm × 250 mm,5 μm,mobile phase: acetonitrile-0. 1% phosphoric acid( 22∶ 78),detection wavelength: 320 nm,flow rate: 1. 0 m L/min,column temperature: 30℃,and injection volume: 10 μL. [Results] The caffeic acid showed a good linear relationship in the range of injection volume of 0. 025 92-0. 259 2 μg( R =0. 999 5). The average recovery rate was 98. 33%( RSD = 1. 85%). L. alata in different production areas of Guangxi contained the caffeic acid,and there was a great difference in the caffeic acid. L. alata in Baise had the highest content of caffeic acid,while that in Guilin had the lowest content of caffeic acid. [Conclusions]This method can accurately determine the content of caffeic acid and is expected provide a scientific basis for the development and utilization of herbal medicine L. alata.展开更多
Brachystemma calycinum D. Don as an important rare medicinal plant, the market prospect is very promising. In this paper, the resource distribution, ecological environment, community structure, domestication of wild c...Brachystemma calycinum D. Don as an important rare medicinal plant, the market prospect is very promising. In this paper, the resource distribution, ecological environment, community structure, domestication of wild cultivar and market demand and status of Brachystemma calycinum were systematically studied, so as to provide a basis for resource development and utilization.展开更多
基金Guangxi Young and Middle-aged University Teachers'Scientific Research Ability Enhancement Project(No.2019KY0341)Foundation of Administration of Traditional Chinese Medicine of Guangxi Zhuang Autonomous Region(No.GZZC2019147)+2 种基金Youth Foundation of Guangxi University of Chinese Medicine(No.2019QN036)University-level Scientific Research Project of Youjiang Medical University for Nationalities(yy2018ky018)Scientific Research Laboratories of National Administration of Traditional Chinese Medicine(Level III):Chemistry and Quality Analysis Laboratory of Chinese(Zhuang)Medicine(Guo Zhong Yi Yao Fa 2009[21]).
文摘[Objectives]This study aimed to investigate the intervention effects of ethanol extract of Laggera alata(D.Don)Sch.Bip.ex Oliv on cirrhotic rats with ascites.[Methods]A total of 100 male SD rats of SPF grade were used.Rat models of cirrhosis and ascites were established.After the last administration,the amount of peritoneal fluid was measured,and the blood of each rat tested was collected for determination of serum AST,ALT and ALB levels,serum K+concentration and plasma Ald level.[Results]In ascitic cirrhotic rats,the livers showed obvious enlargement,the surface of the livers was uneven,and nodules were visible.Compared with the blank group,the amount of peritoneal fluid in the model group increased significantly(P<0.01);and compared with the model group,the amounts of peritoneal fluid in the high and medium-dose ethanol extract groups reduced significantly(P<0.01).Compared with the blank group,the serum ALT and AST levels in the model group increased significantly(P<0.01);and compared with the model group,the serum ALT and AST levels in the high-dose ethanol extract group decreased significantly(P<0.05).Compared with the blank group,the serum K+concentration in the positive group reduced(P<0.05);no significant difference was found in serum K+concentration between the ethanol extract administration groups and the blank group(P>0.05).Compared with the blank group,the plasma Ald levels in the high-dose ethanol extract group and the positive group reduced(P<0.05);and there was no significant difference in serum K+concentration between the rest groups and the blank group(P>0.05).[Conclusions]In the ethanol extract administration groups,the amounts of peritoneal fluid significantly reduced,the serum ALT and AST reduced,and the liver functions improved to a certain extent,indicating that the ethanol extract of L.alata(D.Don)Sch.Bip.ex Oliv has a better correction effect on electrolyte disturbances in cirrhotic rats with ascites.
文摘[Objective] The aim was to study the effect of different treatments on development and growth of Halenia ellipitica D.Don.[Method] Three treatments (urea treatment group, diammonium phosphate treatment group and control group) were set in the experiment with 3 replications to detect plant height,root length, leaf number, branch number, flower number and biomass of Halenia ellipitica D.Don. in all experimental groups.[Result] The leaf number,branch number, flower number and output of crude drug of Halenia ellipitica D.Don. in urea treatment group were more than that of Halenia ellipitica D.Don. in diammonium phosphate treatment group and control group,however,the plant height and root length were not significantly different among all groups.[Conclusion] The urea generated better effect on Halenia ellipitica D.Don. cultivation than that produced by diammonium phosphate treatment.
文摘A new phenolic constituent along with five known compounds were isolated from Fagopyrum dibotrys (D.Don) Hara. The new compound was characterized as 1,3-dimethoxy-2-O-β-xylo-pyranosyl-5-O-β-glucopyranosyl-benzene, by spectroscopic analysis and enzymatic hydrolysis.
基金Supported by Project of National Natural Science Foundation(81660701&81260673)Project of Guangxi Graduate Education Innovation(YJS201625)+2 种基金Natural Science Foundation Project of Guangxi(2016GXNSFAA380148&2014GXNSFAA118208)Program of Key Laboratory for Purification and Quality Analysis of TCM Extraction in Guangxi Universities(Gui Jiao Ke Yan[2014]No.6)Laboratory of Chemistry and Quality Analysis in the Third Level Laboratory for Research of TCM(Zhuang)of State Administration of Traditional Chinese Medicine(Guo Zhong Yi Yao Fa[200]No.21)
文摘[Objectives] To establish a method for determining the content of Laggera alata( D. Don) Sch. Bip. Ex Oliv. using caffeic acid the target component,and to compare the content of caffeic acid in the medicinal materials of L. alata in different production areas of Guangxi.[Methods]The content was determined by Inertsil~ODS-3 chromatographic column C_(18)( 4. 60 mm × 250 mm,5 μm,mobile phase: acetonitrile-0. 1% phosphoric acid( 22∶ 78),detection wavelength: 320 nm,flow rate: 1. 0 m L/min,column temperature: 30℃,and injection volume: 10 μL. [Results] The caffeic acid showed a good linear relationship in the range of injection volume of 0. 025 92-0. 259 2 μg( R =0. 999 5). The average recovery rate was 98. 33%( RSD = 1. 85%). L. alata in different production areas of Guangxi contained the caffeic acid,and there was a great difference in the caffeic acid. L. alata in Baise had the highest content of caffeic acid,while that in Guilin had the lowest content of caffeic acid. [Conclusions]This method can accurately determine the content of caffeic acid and is expected provide a scientific basis for the development and utilization of herbal medicine L. alata.
基金Supported by the Special Fund for Major Research Program of Guangxi Province(GKZ1298001-1-8)Medical Treatment and Public Health Research and Development Project of Guangxi Province(S201416-02)~~
文摘Brachystemma calycinum D. Don as an important rare medicinal plant, the market prospect is very promising. In this paper, the resource distribution, ecological environment, community structure, domestication of wild cultivar and market demand and status of Brachystemma calycinum were systematically studied, so as to provide a basis for resource development and utilization.
