Four-dimensional(4D)printing is an advanced form of three-dimensional(3D)printing with controllable and programmable shape transformation over time.Actuators are used as a controlling factor with multi-stage shape rec...Four-dimensional(4D)printing is an advanced form of three-dimensional(3D)printing with controllable and programmable shape transformation over time.Actuators are used as a controlling factor with multi-stage shape recovery,with emerging opportunities to customize the mechanical properties of bio-inspired structures.The print pattern of shape memory polymer(SMP)fbers strongly afects the achievable resolution,and consequently infuences several other physical and mechanical properties of fabricated actuators.However,the deformations of bio-inspired structures due to actuator layout are more complex because of the presence of the coupling of multi-directional strain.In this study,the initial structure was designed from closed-shell behavior and divided into a general unit and actuator unit,the latter responsible for driving the transformation.Mutual stress confrontation between the actuator and the general unit was considered in the layout thermodynamic model,in order to eliminate the transformation produced by the uncontrolled shape memory behavior of the general unit.Three critical and efective strategies for the layout design of actuators were proposed and then applied to achieve the desired accurate deformation of 3D-printed bilayer structures.Finally,the proposed approach was validated and adopted for fabricating a complex shell-like gripper structure.展开更多
Communication-dependent and software-based distributed energy resources(DERs)are extensively integrated into modern microgrids,providing extensive benefits such as increased distributed controllability,scalability,and...Communication-dependent and software-based distributed energy resources(DERs)are extensively integrated into modern microgrids,providing extensive benefits such as increased distributed controllability,scalability,and observability.However,malicious cyber-attackers can exploit various potential vulnerabilities.In this study,a programmable adaptive security scanning(PASS)approach is presented to protect DER inverters against various power-bot attacks.Specifically,three different types of attacks,namely controller manipulation,replay,and injection attacks,are considered.This approach employs both software-defined networking technique and a novel coordinated detection method capable of enabling programmable and scalable networked microgrids(NMs)in an ultra-resilient,time-saving,and autonomous manner.The coordinated detection method efficiently identifies the location and type of power-bot attacks without disrupting normal NM operations.Extensive simulation results validate the efficacy and practicality of the PASS for securing NMs.展开更多
ERT(electrical resistance tomography) is effective method for visualization of multiphase flows,offering some advantages of rapid response and low cost,so as to explore the transient hydrodynamics.Aiming at this targe...ERT(electrical resistance tomography) is effective method for visualization of multiphase flows,offering some advantages of rapid response and low cost,so as to explore the transient hydrodynamics.Aiming at this target,a fully programmable and reconfigurable FPGA(field programmable gate array)-based Compact PCI(peripheral component interconnect) bus linked sixteen-channel ERT system has been presented.The data acquisition system is carefully designed with function modules of signal generator module;Compact PCI transmission module and data processing module(including data sampling,filtering and demodulating).The processing module incorporates a powerful FPGA with Compact PCI bus for communication,and the measurement process management is conducted in FPGA.Image reconstruction algorithms with different speed and accuracy are also coded for this system.The system has been demonstrated in real time(1400 frames per second for 50 kHz excitation) with signal-noise-ratio above 62 dB and repeatability error below 0.7%.Static experiments have been conducted and the images manifested good resolution relative to the actual object distribution.The parallel ERT system has provided alternative experimental platform for the multiphase flow measurements by the dynamic experiments in terms of concentration and velocity.展开更多
Targeted genome editing is a continually evolving technology employing programmable nucleases to specifically change,insert,or remove a genomic sequence of interest.These advanced molecular tools include meganucleases...Targeted genome editing is a continually evolving technology employing programmable nucleases to specifically change,insert,or remove a genomic sequence of interest.These advanced molecular tools include meganucleases,zinc finger nucleases,transcription activator-like effector nucleases and RNA-guided engineered nucleases(RGENs),which create double-strand breaks at specific target sites in the genome,and repair DNA either by homologous recombination in the presence of donor DNA or via the error-prone non-homologous end-joining mechanism.A recently discovered group of RGENs known as CRISPR/Cas9 gene-editing systems allowed precise genome manipulation revealing a causal association between disease genotype and phenotype,without the need for the reengineering of the specific enzyme when targeting different sequences.CRISPR/Cas9 has been successfully employed as an ex vivo gene-editing tool in embryonic stem cells and patient-derived stem cells to understand pancreatic beta-cell development and function.RNA-guided nucleases also open the way for the generation of novel animal models for diabetes and allow testing the efficiency of various therapeutic approaches in diabetes,as summarized and exemplified in this manuscript.展开更多
By using AP-FIM the varity of the ordered degree of Ni_3Al with L1_2 structure with B content was studied. The possibility of boron improving ductility was also discussed from bonding between Ni and Al atoms, and anti...By using AP-FIM the varity of the ordered degree of Ni_3Al with L1_2 structure with B content was studied. The possibility of boron improving ductility was also discussed from bonding between Ni and Al atoms, and antisite defects in Ni_3Al. The extent of ordering is reduced with an increase in boron content and the autisite defects are most obvious for 0.52at.K B-doped sample that has the best ductility. Some results were verified by X-ray diffraction non. The addition of boron not only influences electron environment at grain boundary but also in the interior of Ni_3Al gm ins, the latter is favorable to improve the ductility of Ni_3Al grains.展开更多
There is an increasing interest of using the Programmable arrays for performing different hardware. In this paper we give an alternative approach and the applications of the Programmable Gate Arrays. We show the field...There is an increasing interest of using the Programmable arrays for performing different hardware. In this paper we give an alternative approach and the applications of the Programmable Gate Arrays. We show the field and the domain where they are more adequate and wihch kind of Programmable array is more efficient to apply. The DPGA and the FPGA are both Programmable Gate Array. They have more possibilities then the conventional devices such as 64 bits microprocessor, however a microprocessor coupled with a programmable array has more opportunity and their implementation is increasing. It is impossible to enumerate all possible uses of Programmable Gate Array. However we use the parameters Latency and throughput. Finite State Machine(FSM), control of data path, processor coupled with a programmable array to build up an alternative approach of the devices and their applications.展开更多
基金the National Natural Science Foundation of China(Nos.51805472,51775489,and 51975386)the Natural Science Foundation of Zhejiang Province,China(No.LZ21E050004).
文摘Four-dimensional(4D)printing is an advanced form of three-dimensional(3D)printing with controllable and programmable shape transformation over time.Actuators are used as a controlling factor with multi-stage shape recovery,with emerging opportunities to customize the mechanical properties of bio-inspired structures.The print pattern of shape memory polymer(SMP)fbers strongly afects the achievable resolution,and consequently infuences several other physical and mechanical properties of fabricated actuators.However,the deformations of bio-inspired structures due to actuator layout are more complex because of the presence of the coupling of multi-directional strain.In this study,the initial structure was designed from closed-shell behavior and divided into a general unit and actuator unit,the latter responsible for driving the transformation.Mutual stress confrontation between the actuator and the general unit was considered in the layout thermodynamic model,in order to eliminate the transformation produced by the uncontrolled shape memory behavior of the general unit.Three critical and efective strategies for the layout design of actuators were proposed and then applied to achieve the desired accurate deformation of 3D-printed bilayer structures.Finally,the proposed approach was validated and adopted for fabricating a complex shell-like gripper structure.
基金This work was supported in part by the National Science Foundation,USA(ECCS-2018492,CNS-2006828,ECCS-2002897,and OIA-2040599).
文摘Communication-dependent and software-based distributed energy resources(DERs)are extensively integrated into modern microgrids,providing extensive benefits such as increased distributed controllability,scalability,and observability.However,malicious cyber-attackers can exploit various potential vulnerabilities.In this study,a programmable adaptive security scanning(PASS)approach is presented to protect DER inverters against various power-bot attacks.Specifically,three different types of attacks,namely controller manipulation,replay,and injection attacks,are considered.This approach employs both software-defined networking technique and a novel coordinated detection method capable of enabling programmable and scalable networked microgrids(NMs)in an ultra-resilient,time-saving,and autonomous manner.The coordinated detection method efficiently identifies the location and type of power-bot attacks without disrupting normal NM operations.Extensive simulation results validate the efficacy and practicality of the PASS for securing NMs.
基金Supported by the National Natural Science Foundation of China (51176141)the Natural Science Foundation of Tianjin(11JCZDJC22500)
文摘ERT(electrical resistance tomography) is effective method for visualization of multiphase flows,offering some advantages of rapid response and low cost,so as to explore the transient hydrodynamics.Aiming at this target,a fully programmable and reconfigurable FPGA(field programmable gate array)-based Compact PCI(peripheral component interconnect) bus linked sixteen-channel ERT system has been presented.The data acquisition system is carefully designed with function modules of signal generator module;Compact PCI transmission module and data processing module(including data sampling,filtering and demodulating).The processing module incorporates a powerful FPGA with Compact PCI bus for communication,and the measurement process management is conducted in FPGA.Image reconstruction algorithms with different speed and accuracy are also coded for this system.The system has been demonstrated in real time(1400 frames per second for 50 kHz excitation) with signal-noise-ratio above 62 dB and repeatability error below 0.7%.Static experiments have been conducted and the images manifested good resolution relative to the actual object distribution.The parallel ERT system has provided alternative experimental platform for the multiphase flow measurements by the dynamic experiments in terms of concentration and velocity.
基金the Akdeniz University Scientific Research Commission and the Scientific and Technological Research Council of Turkey,No.TUBITAK-215S820.
文摘Targeted genome editing is a continually evolving technology employing programmable nucleases to specifically change,insert,or remove a genomic sequence of interest.These advanced molecular tools include meganucleases,zinc finger nucleases,transcription activator-like effector nucleases and RNA-guided engineered nucleases(RGENs),which create double-strand breaks at specific target sites in the genome,and repair DNA either by homologous recombination in the presence of donor DNA or via the error-prone non-homologous end-joining mechanism.A recently discovered group of RGENs known as CRISPR/Cas9 gene-editing systems allowed precise genome manipulation revealing a causal association between disease genotype and phenotype,without the need for the reengineering of the specific enzyme when targeting different sequences.CRISPR/Cas9 has been successfully employed as an ex vivo gene-editing tool in embryonic stem cells and patient-derived stem cells to understand pancreatic beta-cell development and function.RNA-guided nucleases also open the way for the generation of novel animal models for diabetes and allow testing the efficiency of various therapeutic approaches in diabetes,as summarized and exemplified in this manuscript.
基金This project was supported by the National Nature Science Foundation of China!(Grant No.59831020 and 59895156)
文摘By using AP-FIM the varity of the ordered degree of Ni_3Al with L1_2 structure with B content was studied. The possibility of boron improving ductility was also discussed from bonding between Ni and Al atoms, and antisite defects in Ni_3Al. The extent of ordering is reduced with an increase in boron content and the autisite defects are most obvious for 0.52at.K B-doped sample that has the best ductility. Some results were verified by X-ray diffraction non. The addition of boron not only influences electron environment at grain boundary but also in the interior of Ni_3Al gm ins, the latter is favorable to improve the ductility of Ni_3Al grains.
文摘There is an increasing interest of using the Programmable arrays for performing different hardware. In this paper we give an alternative approach and the applications of the Programmable Gate Arrays. We show the field and the domain where they are more adequate and wihch kind of Programmable array is more efficient to apply. The DPGA and the FPGA are both Programmable Gate Array. They have more possibilities then the conventional devices such as 64 bits microprocessor, however a microprocessor coupled with a programmable array has more opportunity and their implementation is increasing. It is impossible to enumerate all possible uses of Programmable Gate Array. However we use the parameters Latency and throughput. Finite State Machine(FSM), control of data path, processor coupled with a programmable array to build up an alternative approach of the devices and their applications.
