BACKGROUND Allergic cutaneous vasculitis(ACV)is a difficult disease to treat.At present,there is no effective treatment for this condition.Traditionally,immunosuppressants and hormones have been primarily used in its ...BACKGROUND Allergic cutaneous vasculitis(ACV)is a difficult disease to treat.At present,there is no effective treatment for this condition.Traditionally,immunosuppressants and hormones have been primarily used in its management,but the treatment effect is suboptimal,and it has several side effects.CASE SUMMARY We present the case of a 19-year-old woman who presented at our hospital with a four-year history of symmetric skin lesions mainly affecting her lower extremities.She had previously undergone treatment with prednisolone acetate,cetirizine hydrochloride,and loratadine tablets but had not experienced any relief in her condition.Thereafter,she was treated with oral traditional Chinese medicine.Her skin damage gradually improved within two months of treatment initiation.After six months,the skin ulcers had completely subsided.No evidence of skin ulcer recurrence was observed during the subsequent follow-up.This report presents the first case of a female patient who received oral Danggui Sini decoction for the treatment of ACV.CONCLUSION Danggui Sini decoction may be a promising oral treatment for ACV patients.展开更多
Objective:allergic granulomatous vas-culitis is relatively rare in clinic.We aimed to analyze the clinical characteristics of allergic granulomatous vasculi-tis.Methods:collecting allergic granulomatous vasculitis pat...Objective:allergic granulomatous vas-culitis is relatively rare in clinic.We aimed to analyze the clinical characteristics of allergic granulomatous vasculi-tis.Methods:collecting allergic granulomatous vasculitis patients in Taihe Hospital from January 2017 to June 2020,sorting out their general information,system involvement and clinical examination results,and analyzing their clini-cal characteristics.Results:a total of 5 patients diagnosed with allergic granulomatous vasculitis were collected,all with multiple organ involvement,including the skin,re-spiratory system,circulatory system,digestive system,urinary system,and nervous system.Respiratory system involvement was mainly due to decreased lung function;60%manifested as obstructive ventilatory dysfunction.Lung biopsy showed a large amount of eosinophil infil-tration in the interstitium of the alveolar septum,and eo-sinophil and fibrin-like exudation in the alveolar cavity.The circulatory system was mainly affected by myocardi-al damage,and patient two(P2)had pericardial effusion.60%of nervous system involvement was central nervous system involvement,and 40%was peripheral nerve in-volvement.Skin system involvement accounted for 60%.Urinary system involvement was mainly manifested as hematuria and proteinuria.Digestive system involvement was mainly manifested as gastritis,gastric ulcer and other diseases.Conclusion:allergic granulomatous vasculitis is clinically rare.The clinical manifestations are atypical and often involve damage to multiple systems.Clinicians need to fully understand the characteristics of the disease and make comprehensive judgments based on the onset process and examination results to avoid misdiagnosis.展开更多
文摘BACKGROUND Allergic cutaneous vasculitis(ACV)is a difficult disease to treat.At present,there is no effective treatment for this condition.Traditionally,immunosuppressants and hormones have been primarily used in its management,but the treatment effect is suboptimal,and it has several side effects.CASE SUMMARY We present the case of a 19-year-old woman who presented at our hospital with a four-year history of symmetric skin lesions mainly affecting her lower extremities.She had previously undergone treatment with prednisolone acetate,cetirizine hydrochloride,and loratadine tablets but had not experienced any relief in her condition.Thereafter,she was treated with oral traditional Chinese medicine.Her skin damage gradually improved within two months of treatment initiation.After six months,the skin ulcers had completely subsided.No evidence of skin ulcer recurrence was observed during the subsequent follow-up.This report presents the first case of a female patient who received oral Danggui Sini decoction for the treatment of ACV.CONCLUSION Danggui Sini decoction may be a promising oral treatment for ACV patients.
文摘Objective:allergic granulomatous vas-culitis is relatively rare in clinic.We aimed to analyze the clinical characteristics of allergic granulomatous vasculi-tis.Methods:collecting allergic granulomatous vasculitis patients in Taihe Hospital from January 2017 to June 2020,sorting out their general information,system involvement and clinical examination results,and analyzing their clini-cal characteristics.Results:a total of 5 patients diagnosed with allergic granulomatous vasculitis were collected,all with multiple organ involvement,including the skin,re-spiratory system,circulatory system,digestive system,urinary system,and nervous system.Respiratory system involvement was mainly due to decreased lung function;60%manifested as obstructive ventilatory dysfunction.Lung biopsy showed a large amount of eosinophil infil-tration in the interstitium of the alveolar septum,and eo-sinophil and fibrin-like exudation in the alveolar cavity.The circulatory system was mainly affected by myocardi-al damage,and patient two(P2)had pericardial effusion.60%of nervous system involvement was central nervous system involvement,and 40%was peripheral nerve in-volvement.Skin system involvement accounted for 60%.Urinary system involvement was mainly manifested as hematuria and proteinuria.Digestive system involvement was mainly manifested as gastritis,gastric ulcer and other diseases.Conclusion:allergic granulomatous vasculitis is clinically rare.The clinical manifestations are atypical and often involve damage to multiple systems.Clinicians need to fully understand the characteristics of the disease and make comprehensive judgments based on the onset process and examination results to avoid misdiagnosis.
