Sarcopenia reflects patient frailty and should be routinely assessed due to its high prevalence in cirrhotic patients awaiting liver transplants.Pre-transplant nutritional optimization should be tailored for patients ...Sarcopenia reflects patient frailty and should be routinely assessed due to its high prevalence in cirrhotic patients awaiting liver transplants.Pre-transplant nutritional optimization should be tailored for patients with a definitive diagnosis of sarcopenia,therefore improving functional status at transplant and reducing posttransplant mortality.Hepatologists and transplant surgeons should have raised awareness regarding sarcopenia and the reflected frailty that hinder posttransplant outcomes.The policymakers should also take into account when modifying the organ allocation model that sarcopenia or frailty might become a decisive factor in allocating organs for cirrhotic patients,in order to ensure post-transplant survival and quality of life.展开更多
Component commonality has been cited as a powerful approach for manufacturers to cope with increased component proliferation and to control inventory costs. To fully realize its potential benefits, one needs a clear u...Component commonality has been cited as a powerful approach for manufacturers to cope with increased component proliferation and to control inventory costs. To fully realize its potential benefits, one needs a clear understanding of its impacts on the system. In this paper, the feasibility of using a simulation model to provide a systematic perspective for manufacturing firms to implement a commonality strategy is demonstrated. Alternative commonality strategies including the stage of employing commonality and the allocation policies are simulated. Several interesting results on effects of commonality, allocation policies, and optimal solutions are obtained. We then summarize qualitative insights and managerial implications into the component commonality design and implementation, and inventory management in a general multi-stage assembly system.展开更多
文摘Sarcopenia reflects patient frailty and should be routinely assessed due to its high prevalence in cirrhotic patients awaiting liver transplants.Pre-transplant nutritional optimization should be tailored for patients with a definitive diagnosis of sarcopenia,therefore improving functional status at transplant and reducing posttransplant mortality.Hepatologists and transplant surgeons should have raised awareness regarding sarcopenia and the reflected frailty that hinder posttransplant outcomes.The policymakers should also take into account when modifying the organ allocation model that sarcopenia or frailty might become a decisive factor in allocating organs for cirrhotic patients,in order to ensure post-transplant survival and quality of life.
文摘Component commonality has been cited as a powerful approach for manufacturers to cope with increased component proliferation and to control inventory costs. To fully realize its potential benefits, one needs a clear understanding of its impacts on the system. In this paper, the feasibility of using a simulation model to provide a systematic perspective for manufacturing firms to implement a commonality strategy is demonstrated. Alternative commonality strategies including the stage of employing commonality and the allocation policies are simulated. Several interesting results on effects of commonality, allocation policies, and optimal solutions are obtained. We then summarize qualitative insights and managerial implications into the component commonality design and implementation, and inventory management in a general multi-stage assembly system.
