Allylation of terminal epoxides(1)to give the homoallylic alcohols(2)and bishomoallylic alcohols(3)can be carried out successfully by allyl bromide and metallic zinc or tin.The effect of substituents on epoxides was s...Allylation of terminal epoxides(1)to give the homoallylic alcohols(2)and bishomoallylic alcohols(3)can be carried out successfully by allyl bromide and metallic zinc or tin.The effect of substituents on epoxides was studied.展开更多
3-Aryl-l,2,4-benzotriazines were conveniently prepared in moderate to good yields from 1,1-bis（benzotriazol-1- yl）methylarenes with allylsamarium bromide/hexamethylphosphramide （allylSmBr/HMPA）. Preliminary result...3-Aryl-l,2,4-benzotriazines were conveniently prepared in moderate to good yields from 1,1-bis（benzotriazol-1- yl）methylarenes with allylsamarium bromide/hexamethylphosphramide （allylSmBr/HMPA）. Preliminary results in- dicate that HMPA may enhance the reducing ability as well as prohibit the nucleophicility of allylSmBr, thus mak- ing allylSmBr/HMPA as a promising single-electron transfer （SET） reagent.展开更多
文摘Allylation of terminal epoxides(1)to give the homoallylic alcohols(2)and bishomoallylic alcohols(3)can be carried out successfully by allyl bromide and metallic zinc or tin.The effect of substituents on epoxides was studied.
基金Acknowledgement This work was financially supported by National Natural Science Foundation of China （No. 20802070） and the research foundation from Key Laboratory of Synthetic Organic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry （CAS）. We thank Professor Ran Hong at SIOC for helpful discus- sions.
文摘3-Aryl-l,2,4-benzotriazines were conveniently prepared in moderate to good yields from 1,1-bis（benzotriazol-1- yl）methylarenes with allylsamarium bromide/hexamethylphosphramide （allylSmBr/HMPA）. Preliminary results in- dicate that HMPA may enhance the reducing ability as well as prohibit the nucleophicility of allylSmBr, thus mak- ing allylSmBr/HMPA as a promising single-electron transfer （SET） reagent.
